Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
D N Abrous, E M Torres, S B Dunnet. Dopaminergic grafts implanted into the neonatal or adult striatum: comparative effects on rotation and paw reaching deficits induced by subsequent unilateral nigrostriatal lesions in adulthood. Neuroscience. vol 54. issue 3. 1993-08-19. PMID:8332254. |
dopaminergic grafts implanted into the neonatal or adult striatum: comparative effects on rotation and paw reaching deficits induced by subsequent unilateral nigrostriatal lesions in adulthood. |
1993-08-19 |
2023-08-12 |
rat |
S N Schiffmann, J J Vanderhaeghe. Caffeine regulates neurotensin and cholecystokinin messenger RNA expression in the rat striatum. Neuroscience. vol 54. issue 3. 1993-08-19. PMID:8332255. |
disruption of nigrostriatal dopaminergic transmission results in a dramatic increase in neurotensin messenger rna and in an induction of cholecystokinin messenger rna in the striatum. |
1993-08-19 |
2023-08-12 |
rat |
S N Schiffmann, J J Vanderhaeghe. Caffeine regulates neurotensin and cholecystokinin messenger RNA expression in the rat striatum. Neuroscience. vol 54. issue 3. 1993-08-19. PMID:8332255. |
we therefore concluded that in the intact striatum normally innervated by dopaminergic fibers, caffeine, probably acting through a presynaptic a2 receptor, induced a relative dopamine depletion which in turn led to the induction of neurotensin and cholecystokinin expression in subsets of striatal neurons. |
1993-08-19 |
2023-08-12 |
rat |
J N DaSilva, M R Kilbourn, E F Domin. In vivo imaging of monoaminergic nerve terminals in normal and MPTP-lesioned primate brain using positron emission tomography (PET) and [11C]tetrabenazine. Synapse (New York, N.Y.). vol 14. issue 2. 1993-08-18. PMID:8332945. |
radioligand uptake into brain is rapid, and at short time periods (10-30 minutes) the higher uptake and retention of the radiotracer in the more densely dopaminergic innervated striatum is clearly visualized. |
1993-08-18 |
2023-08-12 |
monkey |
A Töröcsik, A Rakovska, T Görcs, E S Viz. Effect of neurotensin and immunneutralization with anti-neurotensin-serum on dopaminergic-cholinergic interaction in the striatum. Brain research. vol 612. issue 1-2. 1993-08-13. PMID:8101133. |
these findings indicate that, using field stimulation when dopaminergic, cholinergic and nt-containing neurons are stimulated in concert, nt is capable of releasing both ach and da in the striatum, but its effect on ach release is masked unless the d2 receptor-mediated tonic inhibitory effect of da released from the nigro-striatal pathway is attenuated. |
1993-08-13 |
2023-08-12 |
rat |
S Leonard, D Luthman, J Logel, J Luthman, C Antle, R Freedman, B Hoffe. Acidic and basic fibroblast growth factor mRNAs are increased in striatum following MPTP-induced dopamine neurofiber lesion: assay by quantitative PCR. Brain research. Molecular brain research. vol 18. issue 4. 1993-08-12. PMID:7686995. |
we have found that mptp treatment results in a loss of 95% of dopaminergic function and is accompanied by an increase in expression of both afgf and bfgf in the striatum at 1 week post-lesion. |
1993-08-12 |
2023-08-12 |
mouse |
b' R R Ga\\xc4\\xadnetdinov, I I Miroshnichenko, V S Kudrin, M B Bogdanov, V M Pogorelov, E A Budygin, G I Kovalev, K S Raevski\\xc4\\xa. [A comparative study of the neurochemical profiles of carbidine stereoisomers]. Eksperimental\'naia i klinicheskaia farmakologiia. vol 56. issue 1. 1993-08-12. PMID:8100728.' |
the effects of cis- and trans-isomers of atypical neuroleptic carbidine on the synthesis of dopamine and its autoreceptor regulation in the striatum and nucleus accumbens of rats were examined by blocking decarboxylase of l-aromatic amino acids and interrupting the nerve impulse flow in the dopaminergic neurons. |
1993-08-12 |
2023-08-12 |
rat |
E Arnauld, J Arsaut, J Demotes-Mainar. Functional heterogeneity of the caudate-putamen as revealed by c-fos induction in response to D1 receptor activation. Brain research. Molecular brain research. vol 18. issue 4. 1993-08-12. PMID:8326829. |
these results suggest a functional heterogeneity in the cp in response to dopaminergic drugs, which could reflect the anatomical or neurochemical heterogeneity of the striatum itself and its neuroanatomical connections. |
1993-08-12 |
2023-08-12 |
mouse |
A Macaya, R E Burk. Effect of striatal lesion with quinolinate on the development of substantia nigra dopaminergic neurons: a quantitative morphological analysis. Developmental neuroscience. vol 14. issue 5-6. 1993-07-30. PMID:1363970. |
we conclude that the adult number of sn dopaminergic neurons depends on developmental support by the striatum. |
1993-07-30 |
2023-08-11 |
rat |
R Dimova, J Vuillet, A Nieoullon, L Kerkerian-Le Gof. Ultrastructural features of the choline acetyltransferase-containing neurons and relationships with nigral dopaminergic and cortical afferent pathways in the rat striatum. Neuroscience. vol 53. issue 4. 1993-07-08. PMID:7685068. |
ultrastructural features of the choline acetyltransferase-containing neurons and relationships with nigral dopaminergic and cortical afferent pathways in the rat striatum. |
1993-07-08 |
2023-08-12 |
rat |
R Dimova, J Vuillet, A Nieoullon, L Kerkerian-Le Gof. Ultrastructural features of the choline acetyltransferase-containing neurons and relationships with nigral dopaminergic and cortical afferent pathways in the rat striatum. Neuroscience. vol 53. issue 4. 1993-07-08. PMID:7685068. |
the aim of this study was first to specify the morphology and neuronal environment of the large cholinergic neurons, and second to determine the distribution and mode of termination of the corticostriatal and dopaminergic inputs on these neurons in the rat striatum. |
1993-07-08 |
2023-08-12 |
rat |
J P Herman, F Rouge-Pont, M Le Moal, D N Abrou. Mechanisms of amphetamine-induced rotation in rats with unilateral intrastriatal grafts of embryonic dopaminergic neurons: a pharmacological and biochemical analysis. Neuroscience. vol 53. issue 4. 1993-07-08. PMID:8099430. |
implantation of embryonic dopaminergic neurons into the lesioned striatum leads to a compensation of this rotation. |
1993-07-08 |
2023-08-12 |
rat |
J P Herman, F Rouge-Pont, M Le Moal, D N Abrou. Mechanisms of amphetamine-induced rotation in rats with unilateral intrastriatal grafts of embryonic dopaminergic neurons: a pharmacological and biochemical analysis. Neuroscience. vol 53. issue 4. 1993-07-08. PMID:8099430. |
in a second experiment, dopamine release was monitored by microdialysis in the graft-bearing and the contralateral normal striatum of awake, behaving animals following the administration of amphetamine to test whether the observed rotation could be explained by a higher than normal dopamine release from the implanted dopaminergic neurons. |
1993-07-08 |
2023-08-12 |
rat |
A Bal, M Savasta, M Chritin, F Mennicken, D N Abrous, M Le Moal, C Feuerstein, J P Herma. Transplantation of fetal nigral cells reverses the increase of preproenkephalin mRNA levels in the rat striatum caused by 6-OHDA lesion of the dopaminergic nigrostriatal pathway: a quantitative in situ hybridization study. Brain research. Molecular brain research. vol 18. issue 3. 1993-06-24. PMID:8497184. |
transplantation of fetal nigral cells reverses the increase of preproenkephalin mrna levels in the rat striatum caused by 6-ohda lesion of the dopaminergic nigrostriatal pathway: a quantitative in situ hybridization study. |
1993-06-24 |
2023-08-12 |
rat |
A Bal, M Savasta, M Chritin, F Mennicken, D N Abrous, M Le Moal, C Feuerstein, J P Herma. Transplantation of fetal nigral cells reverses the increase of preproenkephalin mRNA levels in the rat striatum caused by 6-OHDA lesion of the dopaminergic nigrostriatal pathway: a quantitative in situ hybridization study. Brain research. Molecular brain research. vol 18. issue 3. 1993-06-24. PMID:8497184. |
the implantation of embryonic dopaminergic neurons into the denervated striatum led to a complete reversal of this increase and, in grafted animals, levels of ppe mrna were at control values. |
1993-06-24 |
2023-08-12 |
rat |
J E Ahlsko. Cerebral transplantation for Parkinson's disease: current progress and future prospects. Mayo Clinic proceedings. vol 68. issue 6. 1993-06-22. PMID:8497136. |
recently, several us and european centers reported substantial clinical improvement after fetal dopaminergic mesencephalon was grafted into the striatum of patients with parkinson's disease. |
1993-06-22 |
2023-08-12 |
human |
Y Miyagi, T Morioka, M Otsuka, M Fuku. Striatal glucose metabolism and [18F]fluorodopa uptake in a patient with tumor-induced hemiparkinsonism. Neurosurgery. vol 32. issue 5. 1993-06-17. PMID:8492861. |
these data suggest that the tumor may have impaired synaptic function of the striatum as a whole, giving rise to contralateral hemiparkinsonism without an impairment of the presynaptic dopaminergic nerve terminals in the striatum. |
1993-06-17 |
2023-08-12 |
Not clear |
W J Florijn, A H Mulder, D H Versteeg, W H Gispe. Adrenocorticotropin/alpha-melanocyte-stimulating hormone (ACTH/MSH)-like peptides modulate adenylate cyclase activity in rat brain slices: evidence for an ACTH/MSH receptor-coupled mechanism. Journal of neurochemistry. vol 60. issue 6. 1993-06-15. PMID:8388034. |
lesioning of the dopaminergic projections to the striatum did not result in a diminished effect of [nle4,d-phe7]alpha-msh on [3h]cyclic amp accumulation, which indicates that the acth/msh receptor-stimulated adenylate cyclase is not located on striatal dopaminergic terminals. |
1993-06-15 |
2023-08-12 |
rat |
M Hadjiconstantinou, T A Wemlinger, C P Sylvia, J P Hubble, N H Nef. Aromatic L-amino acid decarboxylase activity of mouse striatum is modulated via dopamine receptors. Journal of neurochemistry. vol 60. issue 6. 1993-06-15. PMID:8492125. |
we conclude that aaad is modulated in striatum via dopaminergic receptors. |
1993-06-15 |
2023-08-12 |
mouse |
K Campbell, P Kalén, K Wictorin, C Lundberg, R J Mandel, A Björklun. Characterization of GABA release from intrastriatal striatal transplants: dependence on host-derived afferents. Neuroscience. vol 53. issue 2. 1993-06-11. PMID:8098510. |
the dopamine denervating lesion resulted in an increased k(+)-evoked gaba overflow both in the intact (+76%) and the grafted striata (+181%), suggesting that the tonic dopaminergic inhibitory control of gaba release, seen in the intact striatum, is also present in the grafted striata. |
1993-06-11 |
2023-08-12 |
rat |