Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
L Won, B Ghetti, B Heller, A Helle. In vitro evidence that the reduction in mesencephalic dopaminergic neurons in the weaver heterozygote is not due to a failure in target cell interaction. Experimental brain research. vol 115. issue 1. 1997-09-12. PMID:9224846. |
since the coculture of +/+ striatum with wv/+ mesencephalon did not appear to rescue wv/+ dopaminergic neurons in the aggregates as compared to wv/+ striatum and, wv/+ striatum proved to be a perfectly adequate target for +/+ mesencephalic dopaminergic neurons, it appears that the effect of the wv gene is on the dopaminergic neurons themselves. |
1997-09-12 |
2023-08-12 |
mouse |
D J Surmeier, S T Kita. State-dependent regulation of neuronal excitability by dopamine. Nihon shinkei seishin yakurigaku zasshi = Japanese journal of psychopharmacology. vol 17. issue 2. 1997-09-04. PMID:9201732. |
since the discovery that the loss of the dopaminergic innervation of the striatum resulted in parkinson's disease, physiologists have attempted to understand the role of dopamine on striatal activity. |
1997-09-04 |
2023-08-12 |
Not clear |
J Pascual, M Misieg. [Neurochemistry of Parkinson's disease and parkinsonism plus]. Revista de neurologia. vol 25 Suppl 2. 1997-09-04. PMID:9280680. |
presynaptic dopaminergic markers are reduced over the striatum in all these degenerative parkinsonisms, dopamine receptor changes being more heterogeneous. |
1997-09-04 |
2023-08-12 |
Not clear |
R Bles. [PET and SPECT in Parkinson's disease]. Revista de neurologia. vol 25 Suppl 2. 1997-09-04. PMID:9280681. |
using spect has been demonstrated marked differences of the da transporters located on dopaminergic terminals in the striatum in healthy controls and pd patients. |
1997-09-04 |
2023-08-12 |
Not clear |
C Dugast, P Brun, F Sotty, B Renaud, M F Suaud-Chagn. On the involvement of a tonic dopamine D2-autoinhibition in the regulation of pulse-to-pulse-evoked dopamine release in the rat striatum in vivo. Naunyn-Schmiedeberg's archives of pharmacology. vol 355. issue 6. 1997-08-27. PMID:9205955. |
the dopamine overflow evoked by trains of electrical stimulation pulses applied to the ascending dopaminergic pathway was measured with continuous amperometry in the striatum of anesthetised rats. |
1997-08-27 |
2023-08-12 |
rat |
O Márin, W J Smeets, A Gonzále. Basal ganglia organization in amphibians: development of striatal and nucleus accumbens connections with emphasis on the catecholaminergic inputs. The Journal of comparative neurology. vol 383. issue 3. 1997-08-26. PMID:9205046. |
moreover, the dopaminergic fibers reach the striatum earlier than the nucleus accumbens, and they precede markedly the development of the efferent connections of both brain structures. |
1997-08-26 |
2023-08-12 |
Not clear |
H Yamaguchi, A Aiba, K Nakamura, K Nakao, H Sakagami, K Goto, H Kondo, M Katsuk. Dopamine D2 receptor plays a critical role in cell proliferation and proopiomelanocortin expression in the pituitary. Genes to cells : devoted to molecular & cellular mechanisms. vol 1. issue 2. 1997-08-06. PMID:9140068. |
it has been suggested that the dopaminergic system is involved in the inhibitory control of secretion of pituitary hormones and in the regulation of motor function in the striatum. |
1997-08-06 |
2023-08-12 |
mouse |
P Calabresi, A Pisani, D Centonze, G Bernard. Synaptic plasticity and physiological interactions between dopamine and glutamate in the striatum. Neuroscience and biobehavioral reviews. vol 21. issue 4. 1997-08-05. PMID:9195611. |
moreover, we will also describe the function of the striatum in the integration of glutamatergic and dopaminergic inputs to produce long-term changes of synaptic efficacy (long-term depression, long-term potentiation). |
1997-08-05 |
2023-08-12 |
Not clear |
A E Pollack, S M Turgeon, J S Fin. Apomorphine priming alters the response of striatal outflow pathways to D2 agonist stimulation in 6-hydroxydopamine-lesioned rats. Neuroscience. vol 79. issue 1. 1997-08-04. PMID:9178866. |
changes in striatal outflow, particularly in the striato-nigro-entopeduncular pathway, may contribute to alterations in d2-dependent motor responses observed after chronic dopaminergic stimulation in the dopamine-depleted striatum. |
1997-08-04 |
2023-08-12 |
rat |
R L Watt. The role of dopamine agonists in early Parkinson's disease. Neurology. vol 49. issue 1 Suppl 1. 1997-08-04. PMID:9222273. |
because they act on postsynaptic dopamine receptors of the striatum, dopamine agonists act independent of the synthetic dopaminergic enzyme system and are not dependent on degenerating presynaptic neurons in the substantia nigra. |
1997-08-04 |
2023-08-12 |
Not clear |
K Krobert, I Lopez-Colberg, L A Cunningha. Astrocytes promote or impair the survival and function of embryonic ventral mesencephalon co-grafts: effects of astrocyte age and expression of recombinant brain-derived neurotrophic factor. Experimental neurology. vol 145. issue 2 Pt 1. 1997-07-31. PMID:9217087. |
in culture, primary astrocytes derived from postnatal day 0 (p0) rat striatum and transduced with the bdnf vector increased the survival of embryonic day 15 (e15) dopaminergic vm neurons by approximately threefold and reduced the loss of dopaminergic neurons following 6-ohda treatment by approximately 20%. |
1997-07-31 |
2023-08-12 |
rat |
Z Walker, D C Costa, A G Janssen, R W Walker, G Livingstone, C L Katon. Dementia with lewy bodies: a study of post-synaptic dopaminergic receptors with iodine-123 iodobenzamide single-photon emission tomography. European journal of nuclear medicine. vol 24. issue 6. 1997-07-30. PMID:9169566. |
iodine-123 iodobenzamide single-photon emission tomography (ibzm-spet) measures post-synaptic dopamine d2 neuroreceptor availability in the corpus striatum, but is nevertheless a method for assessing the integrity of the nigrostriatal dopaminergic pathway. |
1997-07-30 |
2023-08-12 |
human |
D J Doudet, G L Chan, J E Holden, K S Morrison, R J Wyatt, T J Rut. Effects of catechol-O-methyltransferase inhibition on the rates of uptake and reversibility of 6-fluoro-L-Dopa trapping in MPTP-induced parkinsonism in monkeys. Neuropharmacology. vol 36. issue 3. 1997-07-24. PMID:9175615. |
the uptake rate constant and the loss rate constant that expresses the reversibility of the uptake process of 6-[18f]fluoro-l-dopa (fdopa) were measured by positron emission tomography in the striatum of normal rhesus monkeys and in monkeys with unilateral lesions of the dopaminergic nigro-striatal pathway, induced by intracarotid injection of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp). |
1997-07-24 |
2023-08-12 |
monkey |
I Strömberg, L Björklund, P Förande. The age of striatum determines the pattern and extent of dopaminergic innervation: a nigrostriatal double graft study. Cell transplantation. vol 6. issue 3. 1997-07-21. PMID:9171161. |
the age of striatum determines the pattern and extent of dopaminergic innervation: a nigrostriatal double graft study. |
1997-07-21 |
2023-08-12 |
Not clear |
I Strömberg, L Björklund, P Förande. The age of striatum determines the pattern and extent of dopaminergic innervation: a nigrostriatal double graft study. Cell transplantation. vol 6. issue 3. 1997-07-21. PMID:9171161. |
in animal models of parkinson's disease, transplanted fetal mesencephalic dopaminergic neurons can innervate the dopamine-depleted host brain, but it is unclear why large portions of the host striatum are left uninnervated. |
1997-07-21 |
2023-08-12 |
Not clear |
I Strömberg, L Björklund, P Förande. The age of striatum determines the pattern and extent of dopaminergic innervation: a nigrostriatal double graft study. Cell transplantation. vol 6. issue 3. 1997-07-21. PMID:9171161. |
during normal development, the dopaminergic innervation first occurs in the form of a dense patchy pattern in the striatum, followed by a widespread nerve fiber network. |
1997-07-21 |
2023-08-12 |
Not clear |
I Strömberg, L Björklund, P Förande. The age of striatum determines the pattern and extent of dopaminergic innervation: a nigrostriatal double graft study. Cell transplantation. vol 6. issue 3. 1997-07-21. PMID:9171161. |
in conclusion, grafted dopaminergic neurons preferably innervate mature striatum with a widespread sparse nerve fiber network, while the innervation of the immature striatum occurs in the form of dense patches. |
1997-07-21 |
2023-08-12 |
Not clear |
I Strömberg, L Björklund, P Förande. The age of striatum determines the pattern and extent of dopaminergic innervation: a nigrostriatal double graft study. Cell transplantation. vol 6. issue 3. 1997-07-21. PMID:9171161. |
once the widespread growth pattern is initiated, the presence of immature striatum does not change the dopaminergic growth pattern. |
1997-07-21 |
2023-08-12 |
Not clear |
L Rioux, P A Frohna, J N Joyce, J S Schneide. The effects of chronic levodopa treatment on pre- and postsynaptic markers of dopaminergic function in striatum of parkinsonian monkeys. Movement disorders : official journal of the Movement Disorder Society. vol 12. issue 2. 1997-07-17. PMID:9087972. |
the effects of chronic levodopa treatment on pre- and postsynaptic markers of dopaminergic function in striatum of parkinsonian monkeys. |
1997-07-17 |
2023-08-12 |
monkey |
W Y Chang, R A Webste. Effect of L-dopa alone and with benserazide on the spontaneous activity of striatal neurones in normal and 6-hydroxydopamine-lesioned rats. British journal of pharmacology. vol 121. issue 2. 1997-07-16. PMID:9154345. |
this study also shows the chronic levodopa/pdi treatment reduces the compensating increased activity of surviving dopaminergic neurones and the functional supersensitivity to dopamine and suggests that the long term administration of levodopa may reduce its own utilization and activity in the striatum and in the treatment of parkinson's disease [corrected]. |
1997-07-16 |
2023-08-12 |
rat |