| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Y Wong, G T Liberatore, G A Donnan, D W Howell. Expression of brain-derived neurotrophic factor and TrkB neurotrophin receptors after striatal injury in the mouse. Experimental neurology. vol 148. issue 1. 1998-01-07. PMID:9398452. |
brain-derived neurotrophic factor (bdnf) promotes the survival and differentiation of nigral dopaminergic neurons and supports the activity of dopaminergic cells grafted into the striatum. |
1998-01-07 |
2023-08-12 |
mouse |
| J Y Wong, G T Liberatore, G A Donnan, D W Howell. Expression of brain-derived neurotrophic factor and TrkB neurotrophin receptors after striatal injury in the mouse. Experimental neurology. vol 148. issue 1. 1998-01-07. PMID:9398452. |
we know that striatal injury is followed by long-term stimulation of dopaminergic activity in the striatum, could bdnf play a role in this phenomenon? |
1998-01-07 |
2023-08-12 |
mouse |
| J Y Wong, G T Liberatore, G A Donnan, D W Howell. Expression of brain-derived neurotrophic factor and TrkB neurotrophin receptors after striatal injury in the mouse. Experimental neurology. vol 148. issue 1. 1998-01-07. PMID:9398452. |
one week after physical injury to the striatum of c57/black mice, just before dopaminergic activation becomes obvious, in situ hybridization on coronal sections through mouse striatum reveals that bdnf mrna expression increases significantly before returning to basal levels within 1 month. |
1998-01-07 |
2023-08-12 |
mouse |
| J Y Wong, G T Liberatore, G A Donnan, D W Howell. Expression of brain-derived neurotrophic factor and TrkB neurotrophin receptors after striatal injury in the mouse. Experimental neurology. vol 148. issue 1. 1998-01-07. PMID:9398452. |
when combined with observations of dopaminergic activation after striatal injury and the neuroprotective effects of bdnf introduced into the striatum, our findings suggest that bdnf and trkbtk- do indeed play a role in dopaminergic regeneration and repair. |
1998-01-07 |
2023-08-12 |
mouse |
| C N Svendsen, M A Caldwell, J Shen, M G ter Borg, A E Rosser, P Tyers, S Karmiol, S B Dunnet. Long-term survival of human central nervous system progenitor cells transplanted into a rat model of Parkinson's disease. Experimental neurology. vol 148. issue 1. 1998-01-07. PMID:9398456. |
progenitor cells were isolated from the developing human central nervous system (cns), induced to divide using a combination of epidermal growth factor and fibroblast growth factor-2, and then transplanted into the striatum of adult rats with unilateral dopaminergic lesions. |
1998-01-07 |
2023-08-12 |
human |
| A Ho, M Blu. Regulation of astroglial-derived dopaminergic neurotrophic factors by interleukin-1 beta in the striatum of young and middle-aged mice. Experimental neurology. vol 148. issue 1. 1998-01-07. PMID:9398477. |
regulation of astroglial-derived dopaminergic neurotrophic factors by interleukin-1 beta in the striatum of young and middle-aged mice. |
1998-01-07 |
2023-08-12 |
mouse |
| A Ho, M Blu. Regulation of astroglial-derived dopaminergic neurotrophic factors by interleukin-1 beta in the striatum of young and middle-aged mice. Experimental neurology. vol 148. issue 1. 1998-01-07. PMID:9398477. |
interleukin-1 beta (il-1 beta) can induce dopaminergic axonal sprouting in the denervated striatum of parkinsonian animals. |
1998-01-07 |
2023-08-12 |
mouse |
| V Chaparro-Huerta, C Beas-Zárate, M U Guerrero, A Feria-Velasc. Nitric oxide involvement in regulating the dopamine transport in the striatal region of rat brain. Neurochemistry international. vol 31. issue 4. 1998-01-06. PMID:9308011. |
results support the hypothesis related to the participation of no on da transport possibly synthesized at the dopaminergic (daergic) terminals in the striatum; also that l-arg concentration may determine alternative mechanisms to regulate the daergic activity at the striatum. |
1998-01-06 |
2023-08-12 |
rat |
| H Shibaguchi, Y Kataoka, S Koizumi, M Kohzuma, M Obana, A Himeno, K Yamashita, K Taniyam. Nitric oxide participates in the stimulatory and neurotoxic action of endothelin on rat striatal dopaminergic neurons. Cellular and molecular neurobiology. vol 17. issue 5. 1998-01-02. PMID:9353589. |
thus, no may work as a promoter in mediation of the stimulatory and neurotoxic action of et-3 on the striatal dopaminergic system, presumably by interacting with interneurons in the striatum. |
1998-01-02 |
2023-08-12 |
rat |
| E Tolosa, F Valldeoriol. Mid-stage parkinsonism with mild motor fluctuations. Clinical neuropharmacology. vol 17 Suppl 2. 1997-12-29. PMID:9358192. |
treatment strategies in patients with mid-stage parkinsonism and mild fluctuations are primarily directed toward enhancing dopaminergic transmission in the striatum. |
1997-12-29 |
2023-08-12 |
Not clear |
| T Abekawa, T Ohmori, T Koyam. Tolerance to the neurotoxic effect of methamphetamine in rats behaviorally sensitized to methamphetamine or amphetamine. Brain research. vol 767. issue 1. 1997-12-23. PMID:9365013. |
a series of experiments was conducted to examine whether rats behaviorally sensitized to methamphetamine (ma) would show supersensitivity or tolerance to the ma-induced neurotoxic effects on dopaminergic and serotonergic nerve terminals in the striatum (st), nucleus accumbens (na) and medial frontal cortex (mfc). |
1997-12-23 |
2023-08-12 |
rat |
| H Mann, B Ladenheim, H Hirata, T H Moran, J L Cade. Differential toxic effects of methamphetamine (METH) and methylenedioxymethamphetamine (MDMA) in multidrug-resistant (mdr1a) knockout mice. Brain research. vol 769. issue 2. 1997-12-23. PMID:9374204. |
the toxic effects of methamphetamine (meth) (2.5, 5.0 and 10.0 mg/kg) and methylenedioxymethamphetamine (mdma) (5.0, 10.0 and 20.0 mg/kg) on dopaminergic systems were assessed in the striatum and of the nucleus accumbens in mdr1a wild-type and knockout mice. |
1997-12-23 |
2023-08-12 |
mouse |
| U Wüllner, D G Standaert, C M Testa, J B Penney, A B Youn. Differential expression of kainate receptors in the basal ganglia of the developing and adult rat brain. Brain research. vol 768. issue 1-2. 1997-12-18. PMID:9369318. |
glur6 was highly expressed in the striatum and subthalamic nucleus and to a lesser extent in the substantia nigra pars reticulata, while no hybridization signal was detectable in the large, presumably dopaminergic neurons of the substantia nigra pars compacta. |
1997-12-18 |
2023-08-12 |
rat |
| A Takahashi, H Ishimaru, Y Ikarashi, E Kishi, Y Maruyam. Comprehensive analysis of neurotransmitters and their metabolites including acetylcholine and choline in rat brain nuclei. Brain research. Brain research protocols. vol 1. issue 1. 1997-12-16. PMID:9385049. |
for example, dopaminergic neuron mediated control of cholinergic interneuron in the striatum and dopaminergic regulation of cortical ach release have been documented. |
1997-12-16 |
2023-08-12 |
rat |
| O Lindval. Neural transplantation: a hope for patients with Parkinson's disease. Neuroreport. vol 8. issue 14. 1997-11-26. PMID:9331903. |
current research strategies to develop neural transplantation as a treatment for pd include (i) to increase da neuron survival and density and extent of the dopaminergic reinnervation in the striatum; (ii) to implant da neurons in denervated regions outside the caudate-putamen and to reconstruct the nigrostriatal pathway; and (iii) to find other sources of cells suitable for grafting. |
1997-11-26 |
2023-08-12 |
human |
| F Gonon, B Bloc. Kinetics and geometry of the excitatory dopaminergic transmission in the rat striatum in vivo. Advances in pharmacology (San Diego, Calif.). vol 42. 1997-11-25. PMID:9327866. |
kinetics and geometry of the excitatory dopaminergic transmission in the rat striatum in vivo. |
1997-11-25 |
2023-08-12 |
rat |
| b' S Ferr\\xc3\\xa. Adenosine-dopamine interactions in the ventral striatum. Implications for the treatment of schizophrenia. Psychopharmacology. vol 133. issue 2. 1997-11-20. PMID:9342776.' |
on the other hand, adenosine antagonists, like caffeine, produce similar effects to increased dopaminergic neurotransmission in the striatum. |
1997-11-20 |
2023-08-12 |
Not clear |
| M A Cenci, K Campbell, A Björklun. Glutamic acid decarboxylase gene expression in the dopamine-denervated striatum: effects of intrastriatal fetal nigral transplants or chronic apomorphine treatment. Brain research. Molecular brain research. vol 48. issue 1. 1997-11-10. PMID:9379836. |
the results show that fetal dopaminergic grafts in the dopamine-denervated striatum restore an inhibitory control on gad67 gene expression in the host neurons and also counteract the up-regulation of gad67 mrna levels induced by chronic apomorphine treatment. |
1997-11-10 |
2023-08-12 |
rat |
| J A Rodríguez-Gómez, M Romero-Ramos, M L Vizuete, J L Venero, J Cano, A Machad. Increased activity and expression of tyrosine hydroxylase in the rat substantia nigra after chronic treatment with nomifensine. Molecular pharmacology. vol 52. issue 4. 1997-11-10. PMID:9380027. |
these results suggest that long-lasting inhibition of the high affinity da uptake system triggers long term regulatory, compensatory mechanisms in the cell body region to preserve normal dopaminergic function in the terminal field in striatum. |
1997-11-10 |
2023-08-12 |
rat |
| S W Tang, D M Helmeste, H Fang, M Li, R Vu, W Bunney, S Potkin, E G Jone. Differential labeling of dopamine and sigma sites by [3H]nemonapride and [3H]raclopride in postmortem human brains. Brain research. vol 765. issue 1. 1997-11-06. PMID:9310388. |
we applied the nemonapride-raclopride subtraction method to postmortem, non-schizophrenic human striatum to examine the variation in dopaminergic receptor binding labeled by these ligands. |
1997-11-06 |
2023-08-12 |
human |