| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H Nagasawa, H Tanji, M Itoh, Y Itoyam. [PET study using 6-[18F]-fluorodopa in Parkinson's disease]. Nihon rinsho. Japanese journal of clinical medicine. vol 55. issue 1. 1997-03-26. PMID:9014452. |
pet study using fdopa revealed presynaptic dopaminergic function in the striatum of nigrostriatal system of the human brain and many studies have performed to clarify the pathogenesis of parkinson's disease. |
1997-03-26 |
2023-08-12 |
human |
| J Booij, G Tissingh, G J Boer, J D Speelman, J C Stoof, A G Janssen, E C Wolters, E A van Roye. [123I]FP-CIT SPECT shows a pronounced decline of striatal dopamine transporter labelling in early and advanced Parkinson's disease. Journal of neurology, neurosurgery, and psychiatry. vol 62. issue 2. 1997-03-20. PMID:9048712. |
the main neuropathological feature in parkinson's disease is a severe degeneration of the dopaminergic neurons in the substantia nigra resulting in a loss of dopamine (da) transporters in the striatum. |
1997-03-20 |
2023-08-12 |
Not clear |
| K X Huang, J R Walter. Dopaminergic regulation of AP-1 transcription factor DNA binding activity in rat striatum. Neuroscience. vol 75. issue 3. 1997-03-19. PMID:8951871. |
dopaminergic regulation of ap-1 transcription factor dna binding activity in rat striatum. |
1997-03-19 |
2023-08-12 |
rat |
| K X Huang, J R Walter. Dopaminergic regulation of AP-1 transcription factor DNA binding activity in rat striatum. Neuroscience. vol 75. issue 3. 1997-03-19. PMID:8951871. |
moreover, the findings provide evidence that the loss of dopaminergic input to the striatum, as occurs in parkinson's disease, induces long-lasting alterations in the regulation of striatal gene expression which may contribute to the disease's progress. |
1997-03-19 |
2023-08-12 |
rat |
| M Poltorak, J R Williams, K D Moore, W J Free. Changes in L1 antigen expression in the rat striatum after substantia nigra lesions. Journal of neural transplantation & plasticity. vol 6. issue 1. 1997-03-19. PMID:8959552. |
in the present study, we examined the effects of dopaminergic deafferentation of the striatum on l1 expression. |
1997-03-19 |
2023-08-12 |
rat |
| E Pérez-Navarro, E Arenas, J Reiriz, N Calvo, J Alberc. Glial cell line-derived neurotrophic factor protects striatal calbindin-immunoreactive neurons from excitotoxic damage. Neuroscience. vol 75. issue 2. 1997-03-14. PMID:8931001. |
however, gdnf messenger rna expression in the striatum starts several days before dopaminergic and other afferent neurons reach the striatum, suggesting additional trophic effects of this factor on striatal neurons. |
1997-03-14 |
2023-08-12 |
rat |
| M Irifune, T Sato, T Nishikawa, T Masuyama, M Nomoto, T Fukuda, M Kawahar. Hyperlocomotion during recovery from isoflurane anesthesia is associated with increased dopamine turnover in the nucleus accumbens and striatum in mice. Anesthesiology. vol 86. issue 2. 1997-03-13. PMID:9054265. |
dopaminergic mechanisms within the nucleus accumbens and striatum play an important role in the control of locomotor activity, and a change in dopamine turnover depends essentially on a change in impulse flow in the dopamine neurons. |
1997-03-13 |
2023-08-12 |
mouse |
| N D Volkow, G J Wang, J S Fowler, J Logan, R Hitzemann, Y S Ding, N Pappas, C Shea, K Piscan. Decreases in dopamine receptors but not in dopamine transporters in alcoholics. Alcoholism, clinical and experimental research. vol 20. issue 9. 1997-03-12. PMID:8986209. |
because d2 receptors in striatum are mainly localized in gamma-aminobutyric acid (gaba) cells these results provide evidence of gabaergic involvement in the dopaminergic abnormalities seen in alcoholics. |
1997-03-12 |
2023-08-12 |
Not clear |
| P Stathis, K Antoniou, Z Papadopoulou-Daifotis, M N Rimikis, D Varono. Risperidone: a novel antipsychotic with many "atypical" properties? Psychopharmacology. vol 127. issue 3. 1997-03-11. PMID:8912395. |
the acute and chronic administration effects of risperidone (ris), a mixed 5ht2/d2 receptor antagonist, versus haloperidol (hal) on dopaminergic and serotoninergic activity were investigated in the rat prefrontal cortex (pfc), and the whole striatum (str) as well as separately, in dorsal striatum (strd) and nucleus accumbens (acb). |
1997-03-11 |
2023-08-12 |
rat |
| N D Volkow, Y S Ding, J S Fowler, G J Wan. Cocaine addiction: hypothesis derived from imaging studies with PET. Journal of addictive diseases. vol 15. issue 4. 1997-03-11. PMID:8943582. |
we postulate that periodic and frequent stimulation of the dopaminergic system secondary to chronic use of cocaine favors activation of a circuit that involves the orbitofrontal cortex, cingulate gyrus, thalamus and striatum. |
1997-03-11 |
2023-08-12 |
human |
| T Tawara, T Fukushima, N Hojo, A Isobe, K Shiwaku, T Setogawa, Y Yaman. Effects of paraquat on mitochondrial electron transport system and catecholamine contents in rat brain. Archives of toxicology. vol 70. issue 9. 1997-03-07. PMID:8831909. |
these results suggest that paraquat after crossing the blood-brain barrier might be reduced to the radical in rat brain, which may damage the brain tissue, especially dopaminergic neurons in striatum. |
1997-03-07 |
2023-08-12 |
rat |
| R J Cabrera, C E Navarr. Progesterone in vitro increases NMDA-evoked [3H] dopamine release from striatal slices in proestrus rats. Neuropharmacology. vol 35. issue 2. 1997-03-05. PMID:8734486. |
the dopaminergic nerve terminals in rat striatum appear to be an important target for progesterone (pg) and the excitatory amino acid glutamate. |
1997-03-05 |
2023-08-12 |
rat |
| R J Cabrera, C E Navarr. Progesterone in vitro increases NMDA-evoked [3H] dopamine release from striatal slices in proestrus rats. Neuropharmacology. vol 35. issue 2. 1997-03-05. PMID:8734486. |
these results indicate a specific action of pg on dopaminergic terminals mediated by nmda receptors and suggest a close interaction between glutamate and dopamine systems in the striatum, apparently modulated by progesterone. |
1997-03-05 |
2023-08-12 |
rat |
| S P Siva. Dopaminergic regulation of postnatal development of dynorphin neurons in rat striatum. Neuropeptides. vol 30. issue 1. 1997-03-05. PMID:8868307. |
dopaminergic regulation of postnatal development of dynorphin neurons in rat striatum. |
1997-03-05 |
2023-08-12 |
rat |
| J Ułas, C W Cotma. Dopaminergic denervation of striatum results in elevated expression of NR2A subunit. Neuroreport. vol 7. issue 11. 1997-02-28. PMID:8905666. |
dopaminergic denervation of striatum results in elevated expression of nr2a subunit. |
1997-02-28 |
2023-08-12 |
rat |
| J Ułas, C W Cotma. Dopaminergic denervation of striatum results in elevated expression of NR2A subunit. Neuroreport. vol 7. issue 11. 1997-02-28. PMID:8905666. |
we therefore studied the effect of dopaminergic denervation of the rat striatum (unilateral 6-ohda lesions of the medial forebrain bundle) on nmda receptors. |
1997-02-28 |
2023-08-12 |
rat |
| K V Baev, K A Greene, F F Marciano, A G Shetter, A N Lieberman, R F Spetzle. Novel heuristics of functional neural networks: implications for future strategies in functional neurosurgery. Stereotactic and functional neurosurgery. vol 65. issue 1-4. 1997-02-27. PMID:8916326. |
a hypothesis is proposed that (a) the skeletomotor basal ganglia-thalamocortical loop functions as a model of the behavior of the body and the environment, and that (b) dopaminergic neurons of the substantia nigra pars compacta comprise the substrates of an error distribution system projecting to the striatum. |
1997-02-27 |
2023-08-12 |
Not clear |
| J H Ryu, K Yanai, X L Zhao, T Watanab. The effect of dopamine D1 receptor stimulation on the up-regulation of histamine H3-receptors following destruction of the ascending dopaminergic neurones. British journal of pharmacology. vol 118. issue 3. 1997-02-14. PMID:8762081. |
these results strongly suggest that the expression of histamine h3-receptors in the striatum and substantia nigra is influenced through d1-receptors by tonic nigrostriatal dopaminergic inputs. |
1997-02-14 |
2023-08-12 |
rat |
| J J Dally, J A Temlett, S A Greenfiel. Differential release of acetylcholinesterase in vivo, from the guinea pig substantia nigra compared to the caudate putamen following dopamine depletion. Neuropharmacology. vol 35. issue 5. 1997-02-13. PMID:8887965. |
the results from this study are discussed in the light of a regulatory mechanism for acetylcholinesterase release from the striatum, which may come into operation depending on the extent of destruction of dopaminergic nigrostriatal neurones. |
1997-02-13 |
2023-08-12 |
Not clear |
| G Pezzoli, O Strada, V Silani, A Zecchinelli, L Perbellini, F Javoy-Agid, P Ghidoni, E D Motti, T Masini, G Scarlato, Y Agid, E C Hirsc. Clinical and pathological features in hydrocarbon-induced parkinsonism. Annals of neurology. vol 40. issue 6. 1997-02-13. PMID:9007099. |
pathological examination and immunohistochemical analysis of the brain revealed severe and widespread dopaminergic neuronal loss, associated with severe gliosis, in the substantia nigra, and almost complete loss of tyrosine hydroxylase immunostaining in the striatum. |
1997-02-13 |
2023-08-12 |
Not clear |