| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anu Planken, Lille Kurvits, Ene Reimann, Liis Kadastik-Eerme, Külli Kingo, Sulev Kõks, Pille Tab. Looking beyond the brain to improve the pathogenic understanding of Parkinson's disease: implications of whole transcriptome profiling of Patients' skin. BMC neurology. vol 17. issue 1. 2017-02-27. PMID:28068941. |
parkinson's disease is a progressive neurodegenerative disease, characterized by symptoms of motor impairment, resulting from the loss of dopaminergic neurons in the midbrain, however non-neuronal symptoms are also common. |
2017-02-27 |
2023-08-13 |
Not clear |
| Ben Wu, Kaifu Xiao, Zhuohua Zhang, Long M. Altered Expression of BioMed research international. vol 2016. 2017-02-10. PMID:27872856. |
altered expression of parkinson's disease (pd) is a severe neurodegenerative disorder caused by progressive loss of dopaminergic neurons in the substantia nigra pars compacta of the midbrain. |
2017-02-10 |
2023-08-13 |
Not clear |
| Ben Newland, Paul Wolff, Dezhong Zhou, Wei Wang, Hong Zhang, Anne Rosser, Wenxin Wang, Carsten Werne. Synthesis of ROS scavenging microspheres from a dopamine containing poly(β-amino ester) for applications for neurodegenerative disorders. Biomaterials science. vol 4. issue 3. 2017-02-06. PMID:26756041. |
furthermore, the concentrations required for radical scavenging were shown to be non-toxic towards dopaminergic sh-sy5y cells as well as primary astrocytes and primary embryonic rat ventral midbrain cultures. |
2017-02-06 |
2023-08-13 |
rat |
| Mohammad Jodeiri Farshbaf, Mahboobeh Forouzanfar, Kamran Ghaedi, Abbas Kiani-Esfahani, Maryam Peymani, Alireza Shoaraye Nejati, Tayebeh Izadi, Khadijeh Karbalaie, Maryam Noorbakhshnia, Soheila Rahgozar, Hossein Baharvand, Mohammad Hossein Nasr-Esfahan. Nurr1 and PPARγ protect PC12 cells against MPP(+) toxicity: involvement of selective genes, anti-inflammatory, ROS generation, and antimitochondrial impairment. Molecular and cellular biochemistry. vol 420. issue 1-2. 2017-02-06. PMID:27435855. |
parkinson's disease (pd) can degenerate dopaminergic (da) neurons in midbrain, substantia-nigra pars compacta. |
2017-02-06 |
2023-08-13 |
Not clear |
| Paul D Dodson, Jakob K Dreyer, Katie A Jennings, Emilie C J Syed, Richard Wade-Martins, Stephanie J Cragg, J Paul Bolam, Peter J Magil. Representation of spontaneous movement by dopaminergic neurons is cell-type selective and disrupted in parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 15. 2017-01-31. PMID:27001837. |
midbrain dopaminergic neurons are essential for appropriate voluntary movement, as epitomized by the cardinal motor impairments arising in parkinson's disease. |
2017-01-31 |
2023-08-13 |
mouse |
| Paul D Dodson, Jakob K Dreyer, Katie A Jennings, Emilie C J Syed, Richard Wade-Martins, Stephanie J Cragg, J Paul Bolam, Peter J Magil. Representation of spontaneous movement by dopaminergic neurons is cell-type selective and disrupted in parkinsonism. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 15. 2017-01-31. PMID:27001837. |
by recording and labeling individual neurons in behaving mice, we show that the representation of brief spontaneous movements in the firing of identified midbrain dopaminergic neurons is cell-type selective. |
2017-01-31 |
2023-08-13 |
mouse |
| Hongjun Xie, Jie W. Silica nanoparticles induce alpha-synuclein induction and aggregation in PC12-cells. Chemico-biological interactions. vol 258. 2017-01-31. PMID:27613482. |
amyloid aggregates of α-synuclein in dopaminergic neurons of the midbrain are considered the hallmark of pd. |
2017-01-31 |
2023-08-13 |
Not clear |
| Yining Chen, Laura E Matheson, Jon T Sakat. Mechanisms underlying the social enhancement of vocal learning in songbirds. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 24. 2017-01-26. PMID:27247385. |
furthermore, social interactions that rapidly enhanced learning increased the activity of noradrenergic and dopaminergic midbrain neurons. |
2017-01-26 |
2023-08-13 |
Not clear |
| Hanne Schevernels, Klaas Bombeke, Ruth M Krebs, C Nico Boehle. Preparing for (valenced) action: The role of differential effort in the orthogonalized go/no-go task. Psychophysiology. vol 53. issue 2. 2017-01-18. PMID:26481327. |
functional magnetic resonance imaging results from this task showed that typical areas of the "reward network," like the dopaminergic midbrain and the striatum, predominantly encode action rather than valence, displaying enhanced activity when preparing for action (go) compared to inaction (no-go). |
2017-01-18 |
2023-08-13 |
Not clear |
| E Mäkinen, J Joutsa, J Isotalo, V Kaasine. No relevant midbrain atrophy in Parkinson's disease. Acta neurologica Scandinavica. vol 134. issue 5. 2017-01-17. PMID:27265349. |
to investigate whether significant midbrain atrophy is present in parkinson's disease (pd), and if so, whether it can be used as a marker of striatal dopaminergic degeneration. |
2017-01-17 |
2023-08-13 |
Not clear |
| Ninuo Xia, Pengbo Zhang, Fang Fang, Zhengyuan Wang, Megan Rothstein, Benjamin Angulo, Rosaria Chiang, James Taylor, Renee A Reijo Per. Transcriptional comparison of human induced and primary midbrain dopaminergic neurons. Scientific reports. vol 6. 2017-01-16. PMID:26842779. |
transcriptional comparison of human induced and primary midbrain dopaminergic neurons. |
2017-01-16 |
2023-08-13 |
human |
| Kaneyasu Nishimura, Daisuke Doi, Bumpei Samata, Shigeo Murayama, Tsuyoshi Tahara, Hirotaka Onoe, Jun Takahash. Estradiol Facilitates Functional Integration of iPSC-Derived Dopaminergic Neurons into Striatal Neuronal Circuits via Activation of Integrin α5β1. Stem cell reports. vol 6. issue 4. 2017-01-11. PMID:26997644. |
here, using wheat-germ agglutinin-based transsynaptic tracing, we show that integrin α5 is selectively expressed in striatal neurons that are innervated by midbrain dopaminergic (da) neurons. |
2017-01-11 |
2023-08-13 |
human |
| Judit Zsuga, Gabor Tajti, Csaba Papp, Bela Juhasz, Rudolf Gesztely. FNDC5/irisin, a molecular target for boosting reward-related learning and motivation. Medical hypotheses. vol 90. 2017-01-06. PMID:27063080. |
in the current article, we compile evidence in support of a link between exercise and the mesocortico-limbic system by elucidating interactions on the axis of muscle - irisin - brain derived neurotrophic factor (bdnf) - and dopaminergic function of the midbrain. |
2017-01-06 |
2023-08-13 |
Not clear |
| Hisaaki Namba, Takeshi Okubo, Hiroyuki Naw. Perinatal Exposure to Neuregulin-1 Results in Disinhibition of Adult Midbrain Dopaminergic Neurons: Implication in Schizophrenia Modeling. Scientific reports. vol 6. 2017-01-04. PMID:26935991. |
perinatal exposure to neuregulin-1 results in disinhibition of adult midbrain dopaminergic neurons: implication in schizophrenia modeling. |
2017-01-04 |
2023-08-13 |
mouse |
| Krystal L Parker, Youngcho Kim, Stephanie L Alberico, Eric B Emmons, Nandakumar S Narayana. Optogenetic approaches to evaluate striatal function in animal models of Parkinson disease. Dialogues in clinical neuroscience. vol 18. issue 1. 2017-01-02. PMID:27069384. |
here, we focus on how optogenetics has been used over the last decade to probe striatal circuits that are involved in parkinson disease, a neurodegenerative condition involving motor and cognitive abnormalities resulting from degeneration of midbrain dopaminergic neurons. |
2017-01-02 |
2023-08-13 |
human |
| Wen Li, Elisabet Englund, Håkan Widner, Bengt Mattsson, Danielle van Westen, Jimmy Lätt, Stig Rehncrona, Patrik Brundin, Anders Björklund, Olle Lindvall, Jia-Yi L. Extensive graft-derived dopaminergic innervation is maintained 24 years after transplantation in the degenerating parkinsonian brain. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 23. 2016-12-23. PMID:27140603. |
clinical trials using cells derived from embryonic ventral mesencephalon have shown that transplanted dopaminergic neurons can survive and function in the long term, as demonstrated by in vivo brain imaging using (18)f-fluorodopa and (11)c-raclopride positron emission tomography. |
2016-12-23 |
2023-08-13 |
Not clear |
| Vincent Didone, Sébastien Masson, Caroline Quoilin, Vincent Seutin, Etienne Quertemon. Correlation between ethanol behavioral sensitization and midbrain dopamine neuron reactivity to ethanol. Addiction biology. vol 21. issue 2. 2016-12-20. PMID:25545401. |
at the end of the sensitization procedure, extracellular recordings were made from dopaminergic neurons in midbrain slices from these mice. |
2016-12-20 |
2023-08-13 |
mouse |
| Huiqing Wang, Yongyi Ye, Zhiyuan Zhu, Liqian Mo, Chunnan Lin, Qifu Wang, Haoyuan Wang, Xin Gong, Xiaozheng He, Guohui Lu, Fengfei Lu, Shizhong Zhan. MiR-124 Regulates Apoptosis and Autophagy Process in MPTP Model of Parkinson's Disease by Targeting to Bim. Brain pathology (Zurich, Switzerland). vol 26. issue 2. 2016-12-19. PMID:25976060. |
parkinson's disease (pd) is the most prevalent movement disorder characterized by selective loss of midbrain dopaminergic (da) neurons. |
2016-12-19 |
2023-08-13 |
mouse |
| Ying Huang, Judith Mylius, Henning Scheich, Michael Brosc. Tonic effects of the dopaminergic ventral midbrain on the auditory cortex of awake macaque monkeys. Brain structure & function. vol 221. issue 2. 2016-12-14. PMID:25433449. |
tonic effects of the dopaminergic ventral midbrain on the auditory cortex of awake macaque monkeys. |
2016-12-14 |
2023-08-13 |
monkey |
| Ying Huang, Judith Mylius, Henning Scheich, Michael Brosc. Tonic effects of the dopaminergic ventral midbrain on the auditory cortex of awake macaque monkeys. Brain structure & function. vol 221. issue 2. 2016-12-14. PMID:25433449. |
this study shows that ongoing electrical stimulation of the dopaminergic ventral midbrain can modify neuronal activity in the auditory cortex of awake primates for several seconds. |
2016-12-14 |
2023-08-13 |
monkey |