| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Emilie Werlen, Matthew W Jone. Modulating the map: dopaminergic tuning of hippocampal spatial coding and interactions. Progress in brain research. vol 219. 2016-10-31. PMID:26072240. |
salient events activate the midbrain dopaminergic system and have important impacts on various aspects of mnemonic function, including the stability of hippocampus-dependent memories. |
2016-10-31 |
2023-08-13 |
Not clear |
| HongNa Yang, Jing Wang, Feng Wang, XiaoDun Liu, Heng Chen, WeiMing Duan, TingYu Q. Dopaminergic Neuronal Differentiation from the Forebrain-Derived Human Neural Stem Cells Induced in Cultures by Using a Combination of BMP-7 and Pramipexole with Growth Factors. Frontiers in neural circuits. vol 10. 2016-10-31. PMID:27147976. |
transplantation of dopaminergic (da) neurons is considered to be the most promising therapeutic strategy for replacing degenerated dopamine cells in the midbrain of parkinson's disease (pd), thereby restoring normal neural circuit function and slow clinical progression of the disease. |
2016-10-31 |
2023-08-13 |
human |
| Rachel J Sizemore, Rong Zhang, Naili Lin, Liping Goddard, Timothy Wastney, Louise C Parr-Brownlie, John N J Reynolds, Dorothy E Oorscho. Marked differences in the number and type of synapses innervating the somata and primary dendrites of midbrain dopaminergic neurons, striatal cholinergic interneurons, and striatal spiny projection neurons in the rat. The Journal of comparative neurology. vol 524. issue 5. 2016-10-24. PMID:26355230. |
marked differences in the number and type of synapses innervating the somata and primary dendrites of midbrain dopaminergic neurons, striatal cholinergic interneurons, and striatal spiny projection neurons in the rat. |
2016-10-24 |
2023-08-13 |
rat |
| Rachel J Sizemore, Rong Zhang, Naili Lin, Liping Goddard, Timothy Wastney, Louise C Parr-Brownlie, John N J Reynolds, Dorothy E Oorscho. Marked differences in the number and type of synapses innervating the somata and primary dendrites of midbrain dopaminergic neurons, striatal cholinergic interneurons, and striatal spiny projection neurons in the rat. The Journal of comparative neurology. vol 524. issue 5. 2016-10-24. PMID:26355230. |
elucidating the link between cellular activity and goal-directed behavior requires a fuller understanding of the mechanisms underlying burst firing in midbrain dopaminergic neurons and those that suppress activity during aversive or non-rewarding events. |
2016-10-24 |
2023-08-13 |
rat |
| Rachel J Sizemore, Rong Zhang, Naili Lin, Liping Goddard, Timothy Wastney, Louise C Parr-Brownlie, John N J Reynolds, Dorothy E Oorscho. Marked differences in the number and type of synapses innervating the somata and primary dendrites of midbrain dopaminergic neurons, striatal cholinergic interneurons, and striatal spiny projection neurons in the rat. The Journal of comparative neurology. vol 524. issue 5. 2016-10-24. PMID:26355230. |
these data from identified neurons are pivotal for interpreting their electrophysiological responses to afferent activity and for generating realistic computer models of neuronal networks of striatal and midbrain dopaminergic function. |
2016-10-24 |
2023-08-13 |
rat |
| Lisa Wagenführ, Anne Karen Meyer, Lara Marrone, Alexander Storc. Oxygen Tension Within the Neurogenic Niche Regulates Dopaminergic Neurogenesis in the Developing Midbrain. Stem cells and development. vol 25. issue 3. 2016-10-20. PMID:26577812. |
oxygen tension within the neurogenic niche regulates dopaminergic neurogenesis in the developing midbrain. |
2016-10-20 |
2023-08-13 |
Not clear |
| Lisa Wagenführ, Anne Karen Meyer, Lara Marrone, Alexander Storc. Oxygen Tension Within the Neurogenic Niche Regulates Dopaminergic Neurogenesis in the Developing Midbrain. Stem cells and development. vol 25. issue 3. 2016-10-20. PMID:26577812. |
oxygen tension is an important factor controlling stem cell proliferation and maintenance in various stem cell populations with a particular relevance in midbrain dopaminergic progenitors. |
2016-10-20 |
2023-08-13 |
Not clear |
| Lisa Wagenführ, Anne Karen Meyer, Lara Marrone, Alexander Storc. Oxygen Tension Within the Neurogenic Niche Regulates Dopaminergic Neurogenesis in the Developing Midbrain. Stem cells and development. vol 25. issue 3. 2016-10-20. PMID:26577812. |
however, all available studies on oxygen effects in dopaminergic neuroprogenitors were performed in vitro and thus it remains unclear whether tissue oxygen tension in the embryonic midbrain is also relevant for the regulation of dopaminergic neurogenesis in vivo. |
2016-10-20 |
2023-08-13 |
Not clear |
| Lisa Wagenführ, Anne Karen Meyer, Lara Marrone, Alexander Storc. Oxygen Tension Within the Neurogenic Niche Regulates Dopaminergic Neurogenesis in the Developing Midbrain. Stem cells and development. vol 25. issue 3. 2016-10-20. PMID:26577812. |
we thus dissect here the effects of oxygen tension in combination with hif-1α conditional knockout on dopaminergic neurogenesis by using a novel experimental design allowing for the control of oxygen tension within the microenvironment of the neurogenic niche of the murine fetal midbrain in vivo. |
2016-10-20 |
2023-08-13 |
Not clear |
| Lisa Wagenführ, Anne Karen Meyer, Lara Marrone, Alexander Storc. Oxygen Tension Within the Neurogenic Niche Regulates Dopaminergic Neurogenesis in the Developing Midbrain. Stem cells and development. vol 25. issue 3. 2016-10-20. PMID:26577812. |
the microenvironment of the midbrain dopaminergic neurogenic niche was detected as hypoxic with oxygen tensions below 1.1%. |
2016-10-20 |
2023-08-13 |
Not clear |
| Lisa Wagenführ, Anne Karen Meyer, Lara Marrone, Alexander Storc. Oxygen Tension Within the Neurogenic Niche Regulates Dopaminergic Neurogenesis in the Developing Midbrain. Stem cells and development. vol 25. issue 3. 2016-10-20. PMID:26577812. |
fetal midbrain hypoxia hampered the generation of dopaminergic neurons and is accompanied with restricted fetal midbrain development. |
2016-10-20 |
2023-08-13 |
Not clear |
| Lisa Wagenführ, Anne Karen Meyer, Lara Marrone, Alexander Storc. Oxygen Tension Within the Neurogenic Niche Regulates Dopaminergic Neurogenesis in the Developing Midbrain. Stem cells and development. vol 25. issue 3. 2016-10-20. PMID:26577812. |
our study provides the initial framework for future studies on molecular mechanisms mediating oxygen regulation of dopaminergic neurogenesis within the fetal midbrain as its natural environment. |
2016-10-20 |
2023-08-13 |
Not clear |
| Ting-Yi Wang, Kiara F Bruggeman, Jessica A Kauhausen, Alexandra L Rodriguez, David R Nisbet, Clare L Paris. Functionalized composite scaffolds improve the engraftment of transplanted dopaminergic progenitors in a mouse model of Parkinson's disease. Biomaterials. vol 74. 2016-10-19. PMID:26454047. |
in vitro we confirmed the ability of the scaffolds to support ventral midbrain (vm) dopamine progenitors, and provide sustained delivery of gdnf - capable of eliciting effects on cell survival and dopaminergic axon growth. |
2016-10-19 |
2023-08-13 |
mouse |
| Venissa Machado, Tanja Zöller, Abdelraheim Attaai, Björn Spitta. Microglia-Mediated Neuroinflammation and Neurotrophic Factor-Induced Protection in the MPTP Mouse Model of Parkinson's Disease-Lessons from Transgenic Mice. International journal of molecular sciences. vol 17. issue 2. 2016-10-19. PMID:26821015. |
parkinson's disease (pd) is a neurodegenerative disease characterised by histopathological and biochemical manifestations such as loss of midbrain dopaminergic (da) neurons and decrease in dopamine levels accompanied by a concomitant neuroinflammatory response in the affected brain regions. |
2016-10-19 |
2023-08-13 |
mouse |
| Venissa Machado, Tanja Zöller, Abdelraheim Attaai, Björn Spitta. Microglia-Mediated Neuroinflammation and Neurotrophic Factor-Induced Protection in the MPTP Mouse Model of Parkinson's Disease-Lessons from Transgenic Mice. International journal of molecular sciences. vol 17. issue 2. 2016-10-19. PMID:26821015. |
moreover, we highlight the contribution of neurotrophic factors as endogenous and/or exogenous molecules to slow the progression of midbrain dopaminergic (mda) neurons and further discuss the potential of combined therapeutic approaches employing neuroinflammation modifying agents and neurotrophic factors. |
2016-10-19 |
2023-08-13 |
mouse |
| R Rumpel, O Baron, A Ratzka, M-L Schröder, M Hohmann, A Effenberg, P Claus, C Groth. Increased innervation of forebrain targets by midbrain dopaminergic neurons in the absence of FGF-2. Neuroscience. vol 314. 2016-10-13. PMID:26642808. |
increased innervation of forebrain targets by midbrain dopaminergic neurons in the absence of fgf-2. |
2016-10-13 |
2023-08-13 |
mouse |
| R Rumpel, O Baron, A Ratzka, M-L Schröder, M Hohmann, A Effenberg, P Claus, C Groth. Increased innervation of forebrain targets by midbrain dopaminergic neurons in the absence of FGF-2. Neuroscience. vol 314. 2016-10-13. PMID:26642808. |
fgf-2 is essential for survival of midbrain dopaminergic (da) neurons and is responsible for their dysplasia and disease-related degeneration. |
2016-10-13 |
2023-08-13 |
mouse |
| Shi-Bin Li, Dan Du, Mazahir T Hasan, Georg Köh. D4 Receptor Activation Differentially Modulates Hippocampal Basal and Apical Dendritic Synapses in Freely Moving Mice. Cerebral cortex (New York, N.Y. : 1991). vol 26. issue 2. 2016-10-11. PMID:25270308. |
furthermore, cell type-specific expression of mcherry in datcre mice generated fluorescence in dorsal ca1 that was highest in lacunosum moleculare and similar in or/rad, indicating that midbrain dopaminergic fibers distribute evenly in or/rad. |
2016-10-11 |
2023-08-13 |
mouse |
| G van der Plasse, R van Zessen, M C M Luijendijk, H Erkan, G D Stuber, G M J Ramakers, R A H Ada. Modulation of cue-induced firing of ventral tegmental area dopamine neurons by leptin and ghrelin. International journal of obesity (2005). vol 39. issue 12. 2016-09-27. PMID:26183405. |
midbrain dopaminergic activity in response to reward-predicting environmental stimuli drives reward-seeking and motivated behavior for food rewards. |
2016-09-27 |
2023-08-13 |
human |
| Carmen Cavada Martíne. [THE THALAMIC DOPAMINERGIC SYSTEM. A NOVEL SYSTEM IN THE PRIMATE BRAIN]. Anales de la Real Academia Nacional de Medicina. vol 131. issue 1. 2016-09-15. PMID:27386678. |
the origin of thalamic dopamine is multiple; it includes dopaminergic nuclei in the hypothalamus, periaqueductal gray, ventral mesencephalon and lateral parabrachial nucleus. |
2016-09-15 |
2023-08-13 |
human |