Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Susan E Maloney, Michael A Rieger, Ream Al-Hasani, Michael R Bruchas, David F Wozniak, Joseph D Doughert. Loss of CELF6 RNA binding protein impairs cocaine conditioned place preference and contextual fear conditioning. Genes, brain, and behavior. vol 18. issue 7. 2020-01-16. PMID:31215739. |
characterization of celf6 gene expression showed high levels in monoaminergic populations such as the dopaminergic midbrain populations. |
2020-01-16 |
2023-08-13 |
mouse |
Fanpeng Zhao, Sandra L Siedlak, Sandy L Torres, Qian Xu, Beisha Tang, Xiongwei Zh. Conditional Haploinsufficiency of β-Catenin Aggravates Neuronal Damage in a Paraquat-Based Mouse Model of Parkinson Disease. Molecular neurobiology. vol 56. issue 7. 2020-01-14. PMID:30519817. |
the canonical wnt pathway is critical for both the development and adulthood survival and homeostatic maintenance of the midbrain dopaminergic (da) neurons. |
2020-01-14 |
2023-08-13 |
mouse |
Shanzheng Yang, Enrique M Toledo, Pedro Rosmaninho, Changgeng Peng, Per Uhlén, Diogo S Castro, Ernest Arena. A Zeb2-miR-200c loop controls midbrain dopaminergic neuron neurogenesis and migration. Communications biology. vol 1. 2020-01-11. PMID:30271956. |
zeb2 is a homeodomain transcription factor that plays pleiotropic functions during embryogenesis, but its role for midbrain dopaminergic (mda) neuron development is unknown. |
2020-01-11 |
2023-08-13 |
Not clear |
Hiromi Sano, Atsushi Namb. The effects of zonisamide on L-DOPA-induced dyskinesia in Parkinson's disease model mice. Neurochemistry international. vol 124. 2019-12-24. PMID:30639196. |
parkinson's disease (pd) is a neurodegenerative disorder caused by the loss of dopaminergic neurons in the midbrain and shows motor dysfunctions. |
2019-12-24 |
2023-08-13 |
mouse |
Karim Fifel, Johanna H Meijer, Tom Deboe. Circadian and Homeostatic Modulation of Multi-Unit Activity in Midbrain Dopaminergic Structures. Scientific reports. vol 8. issue 1. 2019-12-20. PMID:29773830. |
circadian and homeostatic modulation of multi-unit activity in midbrain dopaminergic structures. |
2019-12-20 |
2023-08-13 |
mouse |
Anne C Trutti, Martijn J Mulder, Bernhard Hommel, Birte U Forstman. Functional neuroanatomical review of the ventral tegmental area. NeuroImage. vol 191. 2019-12-20. PMID:30710678. |
although dopamine-producing midbrain structures are bordering, they show significant differences in structure and function that argue for a distinction when studying the functions of the dopaminergic midbrain, especially by means of neuroimaging. |
2019-12-20 |
2023-08-13 |
Not clear |
Sharmili Edwin Thanarajah, Sandra Iglesias, Bojana Kuzmanovic, Lionel Rigoux, Klaas E Stephan, Jens C Brüning, Marc Tittgemeye. Modulation of midbrain neurocircuitry by intranasal insulin. NeuroImage. vol 194. 2019-12-20. PMID:30914385. |
here, we used intranasal administration and task-free functional mri in humans to assess time- and dose-dependent effects of insulin on functional connectivity of the dopaminergic midbrain - and how these effects varied depending on systemic insulin sensitivity as measured by homa-ir. |
2019-12-20 |
2023-08-13 |
human |
Sharmili Edwin Thanarajah, Sandra Iglesias, Bojana Kuzmanovic, Lionel Rigoux, Klaas E Stephan, Jens C Brüning, Marc Tittgemeye. Modulation of midbrain neurocircuitry by intranasal insulin. NeuroImage. vol 194. 2019-12-20. PMID:30914385. |
it suggests that altered insulin sensitivity may impact on dopaminergic projections of the midbrain and might underlie the dysregulation of reward-related and motivational behaviour in obesity and diabetes. |
2019-12-20 |
2023-08-13 |
human |
Aman Chandra Kaushik, Deeksha Gautam, Asma Sindhoo Nangraj, Dong-Qing Wei, Shakti Sah. Protection of Primary Dopaminergic Midbrain Neurons Through Impact of Small Molecules Using Virtual Screening of GPR139 Supported by Molecular Dynamic Simulation and Systems Biology. Interdisciplinary sciences, computational life sciences. vol 11. issue 2. 2019-12-20. PMID:31177377. |
protection of primary dopaminergic midbrain neurons through impact of small molecules using virtual screening of gpr139 supported by molecular dynamic simulation and systems biology. |
2019-12-20 |
2023-08-13 |
Not clear |
Aman Chandra Kaushik, Deeksha Gautam, Asma Sindhoo Nangraj, Dong-Qing Wei, Shakti Sah. Protection of Primary Dopaminergic Midbrain Neurons Through Impact of Small Molecules Using Virtual Screening of GPR139 Supported by Molecular Dynamic Simulation and Systems Biology. Interdisciplinary sciences, computational life sciences. vol 11. issue 2. 2019-12-20. PMID:31177377. |
gpr139 has been found to have effective physiological role in primary dopaminergic midbrain neurons and in central nervous system. |
2019-12-20 |
2023-08-13 |
Not clear |
Aman Chandra Kaushik, Deeksha Gautam, Asma Sindhoo Nangraj, Dong-Qing Wei, Shakti Sah. Protection of Primary Dopaminergic Midbrain Neurons Through Impact of Small Molecules Using Virtual Screening of GPR139 Supported by Molecular Dynamic Simulation and Systems Biology. Interdisciplinary sciences, computational life sciences. vol 11. issue 2. 2019-12-20. PMID:31177377. |
recent reports suggested that the ligand of gpr139 protein inhibits the growth of primary dopaminergic midbrain neurons in central nervous system. |
2019-12-20 |
2023-08-13 |
Not clear |
Satoshi Okuyama, Tomoko Kanzaki, Yoshimi Kotani, Mako Katoh, Atsushi Sawamoto, Mitsunari Nakajima, Yoshiko Furukaw. Continual Treatment with the Peels of Citrus kawachiensis (Kawachi Bankan) Protects against Dopaminergic Neuronal Cell Death in a Lipopolysaccharide-Induced Model of Parkinson's Disease. Journal of nutritional science and vitaminology. vol 65. issue 2. 2019-12-19. PMID:31061292. |
our previous study showed that the subcutaneous administration of auraptene (aur) suppresses inflammatory responses including the hyperactivation of microglia in the substantia nigra (sn) of the midbrain of lipopolysaccharide-induced parkinson's disease (pd)-like mice, as well as inhibits dopaminergic neuronal cell death in this region. |
2019-12-19 |
2023-08-13 |
mouse |
Katja Baur, Arian Hach, Rick E Bernardi, Rainer Spanagel, Hilmar Bading, C Peter Bengtso. c-Fos marking of identified midbrain neurons coactive after nicotine administration in-vivo. The Journal of comparative neurology. vol 526. issue 13. 2019-12-16. PMID:29888787. |
complex circuitry interconnecting dopaminergic and cholinergic regions of the midbrain and mesopontine tegmentum are critical for nicotine associated reward. |
2019-12-16 |
2023-08-13 |
mouse |
Reiho Tsutsumi, Yuria Hori, Takahiro Seki, Yuki Kurauchi, Masahiro Sato, Mutsumi Oshima, Akinori Hisatsune, Hiroshi Katsuk. Involvement of exosomes in dopaminergic neurodegeneration by microglial activation in midbrain slice cultures. Biochemical and biophysical research communications. vol 511. issue 2. 2019-12-16. PMID:30803759. |
involvement of exosomes in dopaminergic neurodegeneration by microglial activation in midbrain slice cultures. |
2019-12-16 |
2023-08-13 |
Not clear |
Reiho Tsutsumi, Yuria Hori, Takahiro Seki, Yuki Kurauchi, Masahiro Sato, Mutsumi Oshima, Akinori Hisatsune, Hiroshi Katsuk. Involvement of exosomes in dopaminergic neurodegeneration by microglial activation in midbrain slice cultures. Biochemical and biophysical research communications. vol 511. issue 2. 2019-12-16. PMID:30803759. |
in the present study, we investigated whether exosomes are involved in dopaminergic neurodegeneration triggered by microglial activation in midbrain slice cultures. |
2019-12-16 |
2023-08-13 |
Not clear |
Jan Kamiński, Adam N Mamelak, Kurtis Birch, Clayton P Mosher, Michele Tagliati, Ueli Rutishause. Novelty-Sensitive Dopaminergic Neurons in the Human Substantia Nigra Predict Success of Declarative Memory Formation. Current biology : CB. vol 28. issue 9. 2019-11-25. PMID:29657115. |
this process depends on hippocampal novelty signals, but it remains unknown how midbrain dopaminergic neurons are modulated by declarative-memory-based information. |
2019-11-25 |
2023-08-13 |
human |
Jennifer M Wenzel, Erik B Oleson, Willard N Gove, Anthony B Cole, Utsav Gyawali, Hannah M Dantrassy, Rebecca J Bluett, Dilyan I Dryanovski, Garret D Stuber, Karl Deisseroth, Brian N Mathur, Sachin Patel, Carl R Lupica, Joseph F Chee. Phasic Dopamine Signals in the Nucleus Accumbens that Cause Active Avoidance Require Endocannabinoid Mobilization in the Midbrain. Current biology : CB. vol 28. issue 9. 2019-11-25. PMID:29681476. |
dopaminergic control of avoidance requires endocannabinoids (ecbs), as perturbing ecb signaling in the midbrain disrupts avoidance, which is rescued by optical stimulation of da neurons. |
2019-11-25 |
2023-08-13 |
Not clear |
Sawaguch. The role of D1-dopamine receptors in working memory-guided movements mediated by frontal cortical areas. Parkinsonism & related disorders. vol 7. issue 1. 2019-11-20. PMID:11008191. |
like the striatum, the frontal motor cortices receive dopaminergic fibers from midbrain dopamine cells and contain high levels of dopamine receptors. |
2019-11-20 |
2023-08-12 |
monkey |
S Raypor. Glutamate is a cotransmitter in ventral midbrain dopamine neurons. Parkinsonism & related disorders. vol 7. issue 3. 2019-11-20. PMID:11331197. |
so it is surprising that the ventral midbrain dopamine neurons, which give rise to the dopaminergic pathway, may themselves also be glutamatergic. |
2019-11-20 |
2023-08-12 |
rat |
Stephen M Stahl, Anton J M Lonne. The Mechanism of Drug-induced Akathsia. CNS spectrums. 2019-11-20. PMID:21406165. |
several lines of evidence suggest that akathisia can be attributed to low activity of dopaminergic projections from the midbrain to the ventral striatum. |
2019-11-20 |
2023-08-12 |
Not clear |