| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Eleni Roussa, Michael Wiehle, Nicole Dünker, Steffen Becker-Katins, Oliver Oehlke, Kerstin Krieglstei. Transforming growth factor beta is required for differentiation of mouse mesencephalic progenitors into dopaminergic neurons in vitro and in vivo: ectopic induction in dorsal mesencephalon. Stem cells (Dayton, Ohio). vol 24. issue 9. 2006-10-06. PMID:16741229. |
transforming growth factor beta is required for differentiation of mouse mesencephalic progenitors into dopaminergic neurons in vitro and in vivo: ectopic induction in dorsal mesencephalon. |
2006-10-06 |
2023-08-12 |
mouse |
| Eleni Roussa, Michael Wiehle, Nicole Dünker, Steffen Becker-Katins, Oliver Oehlke, Kerstin Krieglstei. Transforming growth factor beta is required for differentiation of mouse mesencephalic progenitors into dopaminergic neurons in vitro and in vivo: ectopic induction in dorsal mesencephalon. Stem cells (Dayton, Ohio). vol 24. issue 9. 2006-10-06. PMID:16741229. |
together, the results clearly demonstrate that tgf-beta2 and tgf-beta3 are essential signals for differentiation of midbrain progenitors toward neuronal fate and dopaminergic phenotype. |
2006-10-06 |
2023-08-12 |
mouse |
| Gonçalo Castelo-Branco, Ernest Arena. Function of Wnts in dopaminergic neuron development. Neuro-degenerative diseases. vol 3. issue 1-2. 2006-10-06. PMID:16909030. |
dopaminergic (da) neurons in the ventral midbrain (vm) are one of the major cell types lost in parkinson's disease (pd). |
2006-10-06 |
2023-08-12 |
Not clear |
| Johannes Schwarz, Sigrid C Schwarz, Alexander Storc. Developmental perspectives on human midbrain-derived neural stem cells. Neuro-degenerative diseases. vol 3. issue 1-2. 2006-10-06. PMID:16909036. |
the replacement of dopaminergic (da) neurons in patients with parkinson's disease via implantation of embryonic midbrain tissue was taken from animal experiments to clinical applications. |
2006-10-06 |
2023-08-12 |
human |
| A L McCormack, J G Atienza, J W Langston, D A Di Mont. Decreased susceptibility to oxidative stress underlies the resistance of specific dopaminergic cell populations to paraquat-induced degeneration. Neuroscience. vol 141. issue 2. 2006-10-04. PMID:16677770. |
co-localization studies revealed that calbindin-d28k immunoreactivity overlapped with tyrosine hydroxylase labeling and that, after paraquat administration, (i) the vast majority of midbrain 4-hydroxy-2-nonenal-immunoreactive cells were dopaminergic (tyrosine hydroxylase-immunoreactive), (ii) tyrosine hydroxylase/4-hydroxy-2-nonenal-positive neurons were much more prevalent in a9 than a10, and (iii) all calbindin-d28k-containing neurons were characterized by lack of lipid peroxidation (4-hydroxy-2-nonenal immunoreactivity). |
2006-10-04 |
2023-08-12 |
mouse |
| A L McCormack, J G Atienza, J W Langston, D A Di Mont. Decreased susceptibility to oxidative stress underlies the resistance of specific dopaminergic cell populations to paraquat-induced degeneration. Neuroscience. vol 141. issue 2. 2006-10-04. PMID:16677770. |
results in this paraquat model emphasize that, despite sharing a similar dopaminergic phenotype, different groups of midbrain neurons vary dramatically in their vulnerability to injury. |
2006-10-04 |
2023-08-12 |
mouse |
| M Chalimoniuk, N Lukacova, J Marsala, J Langfor. Alterations of the expression and activity of midbrain nitric oxide synthase and soluble guanylyl cyclase in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinsonism in mice. Neuroscience. vol 141. issue 2. 2006-10-04. PMID:16716528. |
7-nitroindazole prevented a significant increase in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced midbrain guanosine 3',5'-cyclic monophosphate level and neurodegeneration of dopaminergic neurons. |
2006-10-04 |
2023-08-12 |
mouse |
| Przemysław Nowak, Łukasz Labus, Richard M Kostrzewa, Ryszard Bru. DSP-4 prevents dopamine receptor priming by quinpirole. Pharmacology, biochemistry, and behavior. vol 84. issue 1. 2006-10-02. PMID:16675001. |
because 1) dopaminergic neurons originate in midbrain nuclei (substantia nigra and ventral tegmental area), and 2) noradrenergic neurons originate in pontine (locus coeruleus) and medullary areas, it might be presumed that these two monoaminergic systems are independent, not interdependent. |
2006-10-02 |
2023-08-12 |
rat |
| I R Winship, J M P Pakan, K G Todd, D R Wong-Wyli. A comparison of ventral tegmental neurons projecting to optic flow regions of the inferior olive vs. the hippocampal formation. Neuroscience. vol 141. issue 1. 2006-09-28. PMID:16698184. |
the ventral tegmental area (catecholaminergic group a10) is a midbrain region characterized by concentrated dopaminergic immunoreactivity. |
2006-09-28 |
2023-08-12 |
Not clear |
| Cristina M Bäckman, Nasir Malik, Yajun Zhang, Lufei Shan, Alex Grinberg, Barry J Hoffer, Heiner Westphal, Andreas C Toma. Characterization of a mouse strain expressing Cre recombinase from the 3' untranslated region of the dopamine transporter locus. Genesis (New York, N.Y. : 2000). vol 44. issue 8. 2006-09-28. PMID:16865686. |
the dopamine transporter (dat) is highly expressed in dopaminergic neurons of the ventral mesencephalon and regulates neurotransmission by transporting da back into the presynaptic terminals. |
2006-09-28 |
2023-08-12 |
mouse |
| Fengming Yue, Li Cui, Kohei Johkura, Naoko Ogiwara, Katsunori Sasak. Induction of midbrain dopaminergic neurons from primate embryonic stem cells by coculture with sertoli cells. Stem cells (Dayton, Ohio). vol 24. issue 7. 2006-09-27. PMID:16822882. |
induction of midbrain dopaminergic neurons from primate embryonic stem cells by coculture with sertoli cells. |
2006-09-27 |
2023-08-12 |
mouse |
| b' S O Talanov, V F Sahach, M M Oleshko, V O Ma\\xc4\\xads\'ky\\xc4\\xa. [Inhibitors of mitochondrial permeability transition pore prevent apoptosis of dopaminergic neurons in the mesencephalon]. Fiziolohichnyi zhurnal (Kiev, Ukraine : 1994). vol 52. issue 4. 2006-09-26. PMID:16958211.' |
[inhibitors of mitochondrial permeability transition pore prevent apoptosis of dopaminergic neurons in the mesencephalon]. |
2006-09-26 |
2023-08-12 |
Not clear |
| Juliane Hamann, Hans Rommelspacher, Alexander Storch, Heinz Reichmann, Gabriele Gill. Neurotoxic mechanisms of 2,9-dimethyl-beta-carbolinium ion in primary dopaminergic culture. Journal of neurochemistry. vol 98. issue 4. 2006-09-21. PMID:16787411. |
here, we investigated the mechanism of cell death in primary dopaminergic cultures of the mouse mesencephalon mediated by 2,9-me(2)nh(+). |
2006-09-21 |
2023-08-12 |
mouse |
| Aya Sasaki, Tatyana D Sotnikova, Raul R Gainetdinov, Erich D Jarvi. Social context-dependent singing-regulated dopamine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 35. 2006-09-21. PMID:16943558. |
like the mammalian striatum, the songbird striatum receives dense dopaminergic input from the midbrain ventral tegmental area-substantia nigra pars compacta complex. |
2006-09-21 |
2023-08-12 |
Not clear |
| Ikuko Mizuta, Wataru Satake, Yuko Nakabayashi, Chiyomi Ito, Satoko Suzuki, Yoshio Momose, Yoshitaka Nagai, Akira Oka, Hidetoshi Inoko, Jiro Fukae, Yuko Saito, Motoji Sawabe, Shigeo Murayama, Mitsutoshi Yamamoto, Nobutaka Hattori, Miho Murata, Tatsushi Tod. Multiple candidate gene analysis identifies alpha-synuclein as a susceptibility gene for sporadic Parkinson's disease. Human molecular genetics. vol 15. issue 7. 2006-09-19. PMID:16500997. |
parkinson's disease (pd), one of the most common human neurodegenerative diseases, is characterized by the loss of dopaminergic neurons in the substantia nigra of the midbrain. |
2006-09-19 |
2023-08-12 |
human |
| Cristina M Bäckman, Lufei Shan, Ya Jun Zhang, Barry J Hoffer, Sherry Leonard, Juan C Troncoso, Paul Vonsatel, Andreas C Toma. Gene expression patterns for GDNF and its receptors in the human putamen affected by Parkinson's disease: a real-time PCR study. Molecular and cellular endocrinology. vol 252. issue 1-2. 2006-09-12. PMID:16644101. |
glial cell line-derived neurotrophic factor (gdnf), a member of the transforming growth factor-beta superfamily, is a potent trophic factor for dopaminergic neurons of the ventral midbrain, which are known to degenerate during parkinson's disease (pd). |
2006-09-12 |
2023-08-12 |
human |
| Annette Møller Dall, Jens Zimme. Development of DARPP-32-positive parts of fetal pig ganglionic eminence and ventral mesencephalon in organotypic slice co-cultures. Experimental neurology. vol 200. issue 1. 2006-09-05. PMID:16529743. |
neurons from the fetal pig dopaminergic ventral mesencephalon (vm) and basal ganglia anlage (the ganglionic eminence) were co-cultured as organotypic slice cultures to study the development of the two interconnected brain areas. |
2006-09-05 |
2023-08-12 |
Not clear |
| Annette Møller Dall, Jens Zimme. Development of DARPP-32-positive parts of fetal pig ganglionic eminence and ventral mesencephalon in organotypic slice co-cultures. Experimental neurology. vol 200. issue 1. 2006-09-05. PMID:16529743. |
this was used (a) to study the developmental expression of the striatal marker protein, dopamine and adenosine 3,5-monophosphate regulated phospho-protein (darpp-32) in the two parts and (b) to compare innervations of the two parts by tyrosine hydroxylase (th)-positive, dopaminergic fibers from co-cultured slices of the ventral mesencephalon. |
2006-09-05 |
2023-08-12 |
Not clear |
| Sangmi Chung, Byoung-Soo Shin, Michelle Hwang, Thomas Lardaro, Un Jung Kang, Ole Isacson, Kwang-Soo Ki. Neural precursors derived from embryonic stem cells, but not those from fetal ventral mesencephalon, maintain the potential to differentiate into dopaminergic neurons after expansion in vitro. Stem cells (Dayton, Ohio). vol 24. issue 6. 2006-08-25. PMID:16543488. |
neural precursors derived from embryonic stem cells, but not those from fetal ventral mesencephalon, maintain the potential to differentiate into dopaminergic neurons after expansion in vitro. |
2006-08-25 |
2023-08-12 |
mouse |
| Sangmi Chung, Byoung-Soo Shin, Michelle Hwang, Thomas Lardaro, Un Jung Kang, Ole Isacson, Kwang-Soo Ki. Neural precursors derived from embryonic stem cells, but not those from fetal ventral mesencephalon, maintain the potential to differentiate into dopaminergic neurons after expansion in vitro. Stem cells (Dayton, Ohio). vol 24. issue 6. 2006-08-25. PMID:16543488. |
neural precursors (nps) derived from ventral mesencephalon (vm) normally generate dopaminergic (da) neurons in vivo but lose their potential to differentiate into da neurons during mitogenic expansion in vitro, hampering their efficient use as a transplantable and experimental cell source. |
2006-08-25 |
2023-08-12 |
mouse |