| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tomasz Tuzimski, Anna Petruczyni. Determination of Anti-Alzheimer's Disease Activity of Selected Plant Ingredients. Molecules (Basel, Switzerland). vol 27. issue 10. 2022-05-28. PMID:35630702. |
one of the most important therapeutic strategies is controlling the level of acetylcholine-a neurotransmitter in cholinergic synapses-by blocking the degradation of acetylcholine using acetylcholinesterase inhibitors such as tacrine, galantamine, donepezil and rivastigmine. |
2022-05-28 |
2023-08-13 |
Not clear |
| Isaac Oluwatobi Akefe, Victoria Aderonke Adegoke, Ibrahim Yusuf Lamidi, Matthew Phillip Ameh, Enokela Shaibu Idoga, Simon Azubuike Ubah, Itopa Etudaye Ajay. Myrtenal mitigates streptozotocin-induced spatial memory deficit via improving oxido inflammatory, cholinergic and neurotransmitter functions in mice. Current research in pharmacology and drug discovery. vol 3. 2022-05-16. PMID:35570857. |
myrtenal mitigates streptozotocin-induced spatial memory deficit via improving oxido inflammatory, cholinergic and neurotransmitter functions in mice. |
2022-05-16 |
2023-08-13 |
mouse |
| Isaac Oluwatobi Akefe, Victoria Aderonke Adegoke, Ibrahim Yusuf Lamidi, Matthew Phillip Ameh, Enokela Shaibu Idoga, Simon Azubuike Ubah, Itopa Etudaye Ajay. Myrtenal mitigates streptozotocin-induced spatial memory deficit via improving oxido inflammatory, cholinergic and neurotransmitter functions in mice. Current research in pharmacology and drug discovery. vol 3. 2022-05-16. PMID:35570857. |
data from this study demonstrated that the administration of streptozotocin (stz) impaired spatial memory and induced alterations in markers of oxido-inflammatory response, cholinergic function, cytoarchitecture, and neurotransmitter levels in mice hippocampus. |
2022-05-16 |
2023-08-13 |
mouse |
| Sarah Könemann, Melissa von Wyl, Colette Vom Ber. Zebrafish Larvae Rapidly Recover from Locomotor Effects and Neuromuscular Alterations Induced by Cholinergic Insecticides. Environmental science & technology. 2022-05-16. PMID:35575681. |
owing to the importance of acetylcholine as a neurotransmitter, many insecticides target the cholinergic system. |
2022-05-16 |
2023-08-13 |
zebrafish |
| Karoline Martins Dos Santos Larangeira, Davi José de Almeida Moraes, Melina Pires da Silva, Vagner Roberto Antune. Exercise Training and Chemogenetic Activation of the Dorsal Motor Nucleus of the Vagus Rescue the Changes in the Hepatic Vein Glucose Concentration by Central Action of Insulin in SHR. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554371. |
here we aimed to investigate whether the deficiency of central action of insulin to control the hvgc of shr is due to a dysfunction in the cholinergic neurotransmission in the dmnv and which putative neurotransmitter could play a role in this circuitry. |
2022-05-13 |
2023-08-13 |
rat |
| Fatemeh Geranmaye. Cholinergic neurotransmitter system: a potential marker for post-stroke cognitive recovery. Brain : a journal of neurology. 2022-04-19. PMID:35438715. |
cholinergic neurotransmitter system: a potential marker for post-stroke cognitive recovery. |
2022-04-19 |
2023-08-13 |
Not clear |
| Shefali Chaudhary, Simon Zhornitsky, Herta H Chao, Christopher H van Dyck, Chiang-Shan R L. Emotion Processing Dysfunction in Alzheimer's Disease: An Overview of Behavioral Findings, Systems Neural Correlates, and Underlying Neural Biology. American journal of Alzheimer's disease and other dementias. vol 37. 2022-03-31. PMID:35357236. |
finally, the reviewed studies implicating major neurotransmitter systems in anxiety and depression in ad supported altered cholinergic and noradrenergic signaling in ad emotional disorders. |
2022-03-31 |
2023-08-13 |
Not clear |
| Maia A Burjanadze, Manana G Dashniani, Revaz O Solomonia, Gela V Beselia, Lia Tsverava, Vincenzo Lagani, Nino C Chkhikvishvili, Temur L Naneishvili, Lali B Kruashvili, Mariam R Chighladz. Age-related changes in medial septal cholinergic and GABAergic projection neurons and hippocampal neurotransmitter receptors: relationship with memory impairment. Experimental brain research. 2022-03-31. PMID:35357523. |
age-related changes in medial septal cholinergic and gabaergic projection neurons and hippocampal neurotransmitter receptors: relationship with memory impairment. |
2022-03-31 |
2023-08-13 |
rat |
| Ying Xia, Eamonn Eeles, Jurgen Fripp, Donna Pinsker, Paul Thomas, Melissa Latter, Vincent Doré, Amir Fazlollahi, Pierrick Bourgeat, Victor L Villemagne, Elizabeth J Coulson, Stephen Ros. Reduced cortical cholinergic innervation measured using [ NeuroImage. Clinical. vol 34. 2022-03-28. PMID:35344804. |
reduced cortical cholinergic innervation measured using [ dysfunction of the cholinergic basal forebrain (bf) neurotransmitter system, including cholinergic axon denervation of the cortex, plays an important role in cognitive decline and dementia. |
2022-03-28 |
2023-08-13 |
Not clear |
| Zhi-Ru Chen, Jia-Bao Huang, Shu-Long Yang, Fen-Fang Hon. Role of Cholinergic Signaling in Alzheimer's Disease. Molecules (Basel, Switzerland). vol 27. issue 6. 2022-03-26. PMID:35335180. |
acetylcholine, a neurotransmitter secreted by cholinergic neurons, is involved in signal transduction related to memory and learning ability. |
2022-03-26 |
2023-08-13 |
Not clear |
| Marta Kopańska, Anna Łagowska, Barbara Kuduk, Agnieszka Banaś-Ząbczy. Acrylamide Neurotoxicity as a Possible Factor Responsible for Inflammation in the Cholinergic Nervous System. International journal of molecular sciences. vol 23. issue 4. 2022-02-26. PMID:35216144. |
within the cholinergic system, there are cholinergic neurons, anatomical cholinergic structures, the neurotransmitter acetylcholine (ach) and cholinergic receptors. |
2022-02-26 |
2023-08-13 |
Not clear |
| Marta Kopańska, Anna Łagowska, Barbara Kuduk, Agnieszka Banaś-Ząbczy. Acrylamide Neurotoxicity as a Possible Factor Responsible for Inflammation in the Cholinergic Nervous System. International journal of molecular sciences. vol 23. issue 4. 2022-02-26. PMID:35216144. |
the cellular molecular mechanism for inhibiting cytokine synthesis is attributed to acetylcholine (ach), the major vagal neurotransmitter, and the α7 nicotinic receptor (α7nachr) subunit is a key receptor for the cholinergic anti-inflammatory pathway. |
2022-02-26 |
2023-08-13 |
Not clear |
| David L Sultzer, Aaron C Lim, Hailey L Gordon, Brandon C Yarns, Rebecca J Melros. Cholinergic receptor binding in unimpaired older adults, mild cognitive impairment, and Alzheimer's disease dementia. Alzheimer's research & therapy. vol 14. issue 1. 2022-02-08. PMID:35130968. |
cholinergic neurotransmitter system dysfunction contributes to cognitive impairment in alzheimer's disease and other syndromes. |
2022-02-08 |
2023-08-13 |
Not clear |
| Christian Fillafer, Yana S Koll, Matthias F Schneide. Lipid Membrane State Change by Catalytic Protonation and the Implications for Synaptic Transmission. Membranes. vol 12. issue 1. 2022-01-21. PMID:35054529. |
in cholinergic synapses, the neurotransmitter acetylcholine (ach) is rapidly hydrolyzed by esterases to choline and acetic acid (ah). |
2022-01-21 |
2023-08-13 |
Not clear |
| Ana Sofía Vallés, Francisco J Barrante. Dendritic spine membrane proteome and its alterations in autistic spectrum disorder. Advances in protein chemistry and structural biology. vol 128. 2022-01-17. PMID:35034726. |
since cholinergic neurotransmission participates in the regulation of cognitive function (attention, memory, learning processes, cognitive flexibility, social interactions) brain acetylcholine receptors are likely to play an important role in the dysfunctional synapses in asd, either directly or indirectly via the modulatory functions exerted on other neurotransmitter receptor proteins and spine-resident proteins. |
2022-01-17 |
2023-08-13 |
Not clear |
| Ayland C Letsinger, Zhenglin Gu, Jerrel L Yake. α7 nicotinic acetylcholine receptors in the hippocampal circuit: taming complexity. Trends in neurosciences. 2021-12-17. PMID:34916082. |
cholinergic innervation of the hippocampus uses the neurotransmitter acetylcholine (ach) to coordinate neuronal circuit activity while simultaneously influencing the function of non-neuronal cell types. |
2021-12-17 |
2023-08-13 |
Not clear |
| Hong-Bo Zhao, Li-Man Liu, Ning Yu, Yan Zhu, Ling Mei, Jin Chen, Chun Lian. Efferent neurons control hearing sensitivity and protect hearing from noise through the regulation of gap junctions between cochlear supporting cells. Journal of neurophysiology. 2021-12-15. PMID:34907797. |
moc nerve fibers are cholinergic and acetylcholine (ach) is a primary neurotransmitter. |
2021-12-15 |
2023-08-13 |
Not clear |
| Stefano Loizzo, Roberto Rimondini, Gabriele Campana, Andrea Fortuna, Zaira Maroccia, Alessandro Martorana, Giacomo Koc. C57BL/6J and DBA/2J strains present opposite sex differences in flash visual evoked potential latency: A possible confusing factor in gender studies on neurological diseases' transgenic models. Brain research bulletin. vol 176. 2021-12-10. PMID:34391824. |
the cholinergic neurotransmitter system in the brain is crucial in processing information related to cognitive, behavioral, and motor functions. |
2021-12-10 |
2023-08-13 |
mouse |
| b' K Szmicsekov\\xc3\\xa1, L Bies Piv\\xc3\\xa1\\xc4\\x8dkov\\xc3\\xa1, Z Kili\\xc3\\xa1nov\\xc3\\xa1, \\xc4\\xbd Slobodov\\xc3\\xa1, P K\\xc5\\x99enek, A Hrabovsk\\xc3\\xa. Aortic butyrylcholinesterase is reduced in spontaneously hypertensive rats. Physiological research. vol 70. issue 5. 2021-12-09. PMID:34505519.' |
despite the fact that vessels have sparse cholinergic innervation, acetylcholine (ach), the primary neurotransmitter of parasympathetic nervous system, has been commonly used in physiological experiments to assess vascular function. |
2021-12-09 |
2023-08-13 |
rat |
| Aren van Waarde, Sofia Marcolini, Peter Paul de Deyn, Rudi A J O Dierck. PET Agents in Dementia: An Overview. Seminars in nuclear medicine. vol 51. issue 3. 2021-12-02. PMID:33500121. |
classified by the target which the agents visualize, seven groups of tracers can be distinguished, namely radiopharmaceuticals for: (1) misfolded proteins (ß-amyloid, tau, α-synuclein), (2) neuroinflammation (overexpression of translocator protein), (3) elements of the cholinergic system, (4) elements of monoamine neurotransmitter systems, (5) synaptic density, (6) cerebral energy metabolism (glucose transport/ hexokinase), and (7) various other proteins. |
2021-12-02 |
2023-08-13 |
Not clear |