| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tosin A Olasehinde, Oyinlola O Olaoku. The Beneficial Role of Apigenin against Cognitive and Neurobehavioural Dysfunction: A Systematic Review of Preclinical Investigations. Biomedicines. vol 12. issue 1. 2024-01-23. PMID:38255283. |
some of the molecular and biochemical mechanisms of apigenin include activation of the erk/creb/bdnf signalling pathway; modulation of neurotransmitter levels and monoaminergic, cholinergic, dopaminergic and serotonergic systems; inhibition of pro-inflammatory cytokine production; and attenuation of oxidative neuronal damage. |
2024-01-23 |
2024-01-25 |
mouse |
| b' Suzana \\xc5\\xbdunec, Donna Vadlja, Alma Rami\\xc4\\x87, Antonio Zandona, Nikola Marakovi\\xc4\\x87, Iva Brekalo, Ines Primo\\xc5\\xbei\\xc4\\x8d, Maja Katalini\\xc4\\x8. Profiling Novel Quinuclidine-Based Derivatives as Potential Anticholinesterase Drugs: Enzyme Inhibition and Effects on Cell Viability. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203326.' |
the cholinergic system, relying on the neurotransmitter acetylcholine (ach), plays a significant role in muscle contraction, cognition, and autonomic nervous system regulation. |
2024-01-11 |
2024-01-13 |
Not clear |
| Keontae Park, Chang Hyeon Kong, Woo Chang Kang, Mijin Jeon, Won Hyung Lee, Juyeon Lee, Sang Chul Kim, Seo Yun Jung, Jong Hoon Ry. LPC20K modified from krill oil ameliorates the scopolamine-induced cognitive impairment. Behavioural brain research. 2023-12-25. PMID:38145873. |
etiologically, dysfunction of cholinergic neurotransmitter system is prominent in ad. |
2023-12-25 |
2023-12-28 |
Not clear |
| Filippo Basagni, Jose A Ortega, Sine M Bertozzi, Andrea Armirotti, Maria Summa, Rosalia Bertorelli, Manuela Bartolini, Ian R Mellor, Martina Bedeschi, Giovanni Bottegoni, Vittorio Lembo, Anna Minarini, Andrea Cavalli, Michela Rosin. Galantamine-memantine hybrids for Alzheimer's disease: The influence of linker rigidity in biological activity and pharmacokinetic properties. European journal of medicinal chemistry. vol 261. 2023-09-21. PMID:37734258. |
neurodegenerative processes characterizing alzheimer's disease (ad) are strictly related to the impairment of cholinergic and glutamatergic neurotransmitter systems which provoke synaptic loss. |
2023-09-21 |
2023-10-07 |
Not clear |
| Joseph V Martin, Pradip K Sarka. Nongenomic roles of thyroid hormones and their derivatives in adult brain: are these compounds putative neurotransmitters? Frontiers in endocrinology. vol 14. 2023-09-13. PMID:37701902. |
furthermore, thyronines bind specifically to other defined neurotransmitter receptors, including gabaergic, catecholaminergic, glutamatergic, serotonergic and cholinergic systems. |
2023-09-13 |
2023-10-07 |
Not clear |
| Ayokunle Olubode Ademosun, Olufunke Florence Ajeigbe, Bodun Oluwaseun Lawrence, Ganiyu Obo. Modulatory Effects of Cannabis Sativa Co-administration with Tramadol and Codeine on Cognitive Function in Male Rats. Neurotoxicology. 2023-08-31. PMID:37652187. |
this study reported the mechanism behind the neurotoxicity of cnb, tmd, and cde on rats' cognitive, cholinergic, purinergic, and antioxidant enzymes as a consequence of the drastic reduction in cholinesterase enzyme activities leading to neurotransmitter poisoning. |
2023-08-31 |
2023-09-07 |
rat |
| Francisco Nieto-Escamez, Esteban Obrero-Gaitán, Irene Cortés-Pére. Visual Dysfunction in Parkinson's Disease. Brain sciences. vol 13. issue 8. 2023-08-26. PMID:37626529. |
similarly, although the involvement of different neurotransmitter systems is controversial, data about neurochemical alterations related to visual impairments are presented, especially dopaminergic, cholinergic, and serotoninergic systems. |
2023-08-26 |
2023-09-07 |
Not clear |
| Moncef Zoual. Pharmacological and Electroceutical Targeting of the Cholinergic Anti-Inflammatory Pathway in Autoimmune Diseases. Pharmaceuticals (Basel, Switzerland). vol 16. issue 8. 2023-08-26. PMID:37631004. |
in the cholinergic anti-inflammatory pathway, the vagus nerve, its pivotal neurotransmitter acetylcholine, together with the corresponding receptors play a key role in modulating the immune response of mammals. |
2023-08-26 |
2023-09-07 |
Not clear |
| Yaoyao Ren, Shengtao Q. Constituent isoflavones of Puerariae radix as a potential neuroprotector in cognitive impairment: Evidence from preclinical studies. Ageing research reviews. 2023-08-24. PMID:37619620. |
these isoflavones prevent aβ aggregation, inhibit tau hyperphosphorylation, increase cholinergic neurotransmitter levels, reduce neuroinflammation and oxidative stress, improve synaptic plasticity, promote nerve regeneration, and prevent apoptosis. |
2023-08-24 |
2023-09-07 |
Not clear |
| A M Dzhafarova, M B Saidov, N K Klichkhano. The Time Profile of the Effects of Moderate Hypothermia on Synaptic Acetylcholinesterase in Rat Brain. Bulletin of experimental biology and medicine. 2023-07-18. PMID:37462806. |
hypothermia in homeotherms significantly affects the neurotransmitter systems of the brain, including the cholinergic system. |
2023-07-18 |
2023-08-14 |
rat |
| Kurt A Jellinge. Mild cognitive impairment in dementia with Lewy bodies: an update and outlook. Journal of neural transmission (Vienna, Austria : 1996). 2023-07-07. PMID:37418039. |
biomarkers are slowing of the eeg rhythms, atrophy of hippocampus and nucleus basalis of meynert, temporoparietal hypoperfusion, signs of degeneration of the nigrostriatal dopaminergic, cholinergic and other neurotransmitter systems, and inflammation. |
2023-07-07 |
2023-08-14 |
Not clear |
| Aditya Nair, Yue Yang Teo, George J Augustine, Martin Gra. A functional logic for neurotransmitter corelease in the cholinergic forebrain pathway. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 28. 2023-07-03. PMID:37399414. |
a functional logic for neurotransmitter corelease in the cholinergic forebrain pathway. |
2023-07-03 |
2023-08-14 |
Not clear |
| Aditya Nair, Yue Yang Teo, George J Augustine, Martin Gra. A functional logic for neurotransmitter corelease in the cholinergic forebrain pathway. Proceedings of the National Academy of Sciences of the United States of America. vol 120. issue 28. 2023-07-03. PMID:37399414. |
such cholinergic switching between subcircuits provides a potential logic for neurotransmitter corelease in implementing behaviorally relevant computations. |
2023-07-03 |
2023-08-14 |
Not clear |
| Shangwen Jing, Xinyue Wang, Zerong Zhang, Dandan Cao, Kongli Huang, Yuting Wang, Zhuangzhuang Liu, Shijie Su, Qi Wan. Hesperetin attenuates cognitive dysfunction via SIRT6/NLRP3 pathway in scopolamine-induced mice. Metabolic brain disease. 2023-06-29. PMID:37382831. |
the levels of proinflammatory factors, oxidant stress, and the cholinergic neurotransmitter were detected by real-time quantitative fluorescence pcr (rt-qpcr) or biochemical reagent kits. |
2023-06-29 |
2023-08-14 |
mouse |
| Mallikarjuna Nimgampalle, Harshini Chakravarthy, Sapana Sharma, Shruti Shree, Anoop Ramachandra Bhat, Jangampalli Adi Pradeepkiran, Vasudharani Devanatha. Neurotransmitter Systems in the Etiology of Major Neurological Disorders: Emerging Insights and Therapeutic Implications. Ageing research reviews. 2023-06-29. PMID:37385351. |
neurotransmitter systems are classified as cholinergic, glutamatergic, gabaergic, dopaminergic, serotonergic, histaminergic, or aminergic systems, depending on the type of neurotransmitter secreted by the neuron, allowing effector organs to carry out specific functions by sending nerve impulses. |
2023-06-29 |
2023-08-14 |
Not clear |
| G Brand, C Bontempi, L Jacquo. Impact of deep brain stimulation (DBS) on olfaction in Parkinson's disease: Clinical features and functional hypotheses. Revue neurologique. 2023-06-10. PMID:37301657. |
the functional hypotheses also suggest complex mechanisms of cholinergic neurotransmitter interactions involved in these pathways. |
2023-06-10 |
2023-08-14 |
Not clear |
| Alexandra Ure, Georgina R Cox, Richard Haslam, Katrina William. Acetylcholinesterase inhibitors for autistic spectrum disorders. The Cochrane database of systematic reviews. vol 6. 2023-06-02. PMID:37267443. |
acetylcholine is a neurotransmitter for the cholinergic system and has a role in attention, novelty seeking, and memory. |
2023-06-02 |
2023-08-14 |
Not clear |
| Shah Alam Khan, Mohammad Jawaid Akhtar, Urvashee Gogoi, Dhanalekshmi Unnikrishnan Meenakshi, Aparoop Da. An Overview of 1,2,3-triazole-Containing Hybrids and Their Potential Anticholinesterase Activities. Pharmaceuticals (Basel, Switzerland). vol 16. issue 2. 2023-06-01. PMID:37259329. |
acetylcholine (ach) neurotransmitter of the cholinergic system in the brain is involved in learning, memory, stress responses, and cognitive functioning. |
2023-06-01 |
2023-08-14 |
Not clear |
| Meng Zhang, Li-Yuan Liu, Yong Xu, Wen-Zhi Wang, Nian-Zhuang Qiu, Fang-Fang Zhang, Feng Zhang, Xiao-Dan Wang, Wei Chen, Xiao-Yan Xu, Yong-Feng Gao, Mei-Hua Chen, Yu-Qin Li, Han-Ting Zhang, Hao Wan. Imbalance of multiple neurotransmitter pathways leading to depression-like behavior and cognitive dysfunction in the triple transgenic mouse model of Alzheimer disease. Metabolic brain disease. 2023-05-31. PMID:37256468. |
the complex and diverse mechanism appears not only relevant to the imbalance of multiple neurotransmitter pathways, including the transmitters and receptors of the monoaminergic, gabaergic, histaminergic, and cholinergic systems, but also related to the changes in l-arginine and creb signaling molecules. |
2023-05-31 |
2023-08-14 |
mouse |
| Neža Žnidaršič, Malan Štrbenc, Neža Grgurevič, Tomaž Sno. Potential revival of cholinesterase inhibitors as drugs in veterinary medicine. Frontiers in veterinary science. vol 10. 2023-03-20. PMID:36937006. |
the cholinergic system is involved in the regulation of all organ systems and has acetylcholine (ach) as almost its only neurotransmitter. |
2023-03-20 |
2023-08-14 |
Not clear |