| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria I Lazarova, Lyubka P Tancheva, Krasimira N Tasheva, Petko N Denev, Diamara N Uzunova, Miroslava O Stefanova, Elina R Tsvetanova, Almira P Georgieva, Reni E Kalfi. Effects of Sideritis scardica Extract on Scopolamine-Induced Learning and Memory Impairment in Mice. Journal of Alzheimer's disease : JAD. 2023-03-06. PMID:36872784. |
the neurodegenerative process in alzheimer's disease, one of the most common types of dementia worldwide, mostly affects the cholinergic neurotransmitter system and, to a lesser extent, the monoaminergic one. |
2023-03-06 |
2023-08-14 |
mouse |
| Kevin R Duque, Joaquin A Vizcarra, Emily J Hill, Alberto J Espa. Disease-modifying vs symptomatic treatments: Splitting over lumping. Handbook of clinical neurology. vol 193. 2023-02-21. PMID:36803811. |
while this convergent approach has resulted in important successes in trials of symptomatic therapies, largely aimed at correcting common neurotransmitter deficiencies (e.g., cholinergic deficiency in alzheimer's disease or dopaminergic deficiency in parkinson's disease), it has been consistently futile in trials of neuroprotective or disease-modifying interventions. |
2023-02-21 |
2023-08-14 |
human |
| Kristin R Anderson, Peter J Rogu, Talulla B Palumbo, Julie M Miw. Abnormal response to chronic social defeat stress and fear extinction in a mouse model of cholinergic dysregulation. Research square. 2023-02-13. PMID:36778356. |
the cholinergic neurotransmitter system drives attention to salient stimuli, such as stressors, and aids in orchestrating the proper neural and behavioral response. |
2023-02-13 |
2023-08-14 |
mouse |
| Hu-Jiang Shi, Shuang Wang, Xin-Ping Wang, Rui-Xin Zhang, Li-Juan Zh. Hippocampus: Molecular, Cellular, and Circuit Features in Anxiety. Neuroscience bulletin. 2023-01-21. PMID:36680709. |
studies of hippocampal neurotransmitter systems, including glutamatergic, gabaergic, cholinergic, dopaminergic, and serotonergic systems, have contributed to the interpretation of the underlying neural mechanisms of anxiety. |
2023-01-21 |
2023-08-14 |
Not clear |
| Ashok Chakraborty, Anil Diwa. Depression and Parkinson's disease: a Chicken-Egg story. AIMS neuroscience. vol 9. issue 4. 2023-01-20. PMID:36660077. |
in addition, it may involve other neurotransmitter systems such as the noradrenergic, serotonergic, cholinergic and noradrenergic systems as well. |
2023-01-20 |
2023-08-14 |
Not clear |
| Júlia L B Simões, Leilane D Sobierai, Inayá F Leal, Miriam V R Dos Santos, João Victor Coiado, Margarete D Bagatin. Action of the purinergic and cholinergic anti-inflammatory pathways on oxidative stress in patients with Alzheimer's disease in the context of the COVID-19 pandemic. Neuroscience. 2022-12-16. PMID:36526078. |
the cholinergic system, through neurons and the neurotransmitter acetylcholine (ach), modulates various physiological pathways, such as the response to stress, sleep and wakefulness, sensory information, and the cognitive system. |
2022-12-16 |
2023-08-14 |
Not clear |
| Sophia B Gibson, Elan Ness-Cohn, Erik C Anderse. Benzimidazoles cause lethality by inhibiting the function of Caenorhabditis elegans neuronal beta-tubulin. International journal for parasitology. Drugs and drug resistance. vol 20. 2022-11-04. PMID:36332489. |
subsetting neuronal expression of ben-1 based on the neurotransmitter system further restricted ben-1 function in cholinergic neurons to cause bz susceptibility. |
2022-11-04 |
2023-08-14 |
caenorhabditis_elegans |
| Faisal Alosaimi, Jackson Tyler Boonstra, Sonny Tan, Yasin Temel, Ali Jahanshah. The role of neurotransmitter systems in mediating deep brain stimulation effects in Parkinson's disease. Frontiers in neuroscience. vol 16. 2022-10-24. PMID:36278000. |
furthermore, ample preclinical and clinical evidence indicates that dbs influences neurotransmitter dynamics in pd, particularly the effects of subthalamic nucleus (stn) dbs on striatal dopaminergic and glutamatergic systems; pallidum dbs on striatal dopaminergic and gabaergic systems; pedunculopontine nucleus dbs on cholinergic systems; and stn-dbs on locus coeruleus (lc) noradrenergic system. |
2022-10-24 |
2023-08-14 |
Not clear |
| Yuanyan Zi, Justin R Barker, Hugh J MacIsaac, Ruihan Zhang, Robin Gras, Ying-Chih Chiang, Yuan Zhou, Fangchi Lu, Wenwen Cai, Chunxiao Sun, Xuexiu Chan. Identification of neurotoxic compounds in cyanobacteria exudate mixtures. The Science of the total environment. 2022-10-08. PMID:36208737. |
cholinergic, dopaminergic and serotonergic neurotransmitter systems). |
2022-10-08 |
2023-08-14 |
Not clear |
| Sushmaa Chandralekha Selvakumar, K Auxzilia Preethi, Deusdedit Tusubira, Durairaj Seka. MicroRNAs in the epigenetic regulation of disease progression in Parkinson's disease. Frontiers in cellular neuroscience. vol 16. 2022-10-03. PMID:36187290. |
however, other neurotransmitter systems like serotoninergic, glutamatergic, noradrenergic, adrenergic, cholinergic, tryptaminergic, and peptidergic appear to be affected as well. |
2022-10-03 |
2023-08-14 |
Not clear |
| Kholoud I Eissa, Mona M Kamel, Lamia W Mohamed, Asmaa E Kassa. Development of new Alzheimer's disease drug candidates using donepezil as a key model. Archiv der Pharmazie. 2022-09-23. PMID:36149034. |
it is a pathologically complicated, multifactorial disease characterized by β-amyloid precipitation, β-amyloid oligomer production, decrease in cholinergic function, and dysregulation of other neurotransmitter systems. |
2022-09-23 |
2023-08-14 |
Not clear |
| Ombretta Paladino, Arianna Moranda, Carla Falug. Spatiotemporal role of muscarinic signaling in early chick development: exposure to cholinomimetic agents by a mathematical model. Cell biology and toxicology. 2022-09-13. PMID:36098822. |
awareness is growing that, besides several neurotoxic effects, cholinomimetic drugs able to interfere the cholinergic neurotransmitter system may exert a teratogen effect in developing embryos of vertebrate and invertebrate organisms. |
2022-09-13 |
2023-08-14 |
chicken |
| Omkar N Athavale, Leo K Cheng, Alys R Clark, Recep Avci, Peng D. Mathematical Modeling of Gastric Slow Waves During Electrical Field Stimulation. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2022. 2022-09-10. PMID:36086185. |
a 21 % reduction in slow wave amplitude occurred when the cholinergic pathway was blocked, compared to a 46% reduction when no neurotransmitter pathways were blocked. |
2022-09-10 |
2023-08-14 |
Not clear |
| Saiko Okamoto, Mihoko Ishizawa, Satoki Inoue, Hideaki Sakuramot. Use of Automated Infrared Pupillometry to Predict Delirium in the Intensive Care Unit: A Prospective Observational Study. SAGE open nursing. vol 8. 2022-09-09. PMID:36081493. |
disturbances in the sympathetic neurons, including cholinergic neurons, have been reported to cause delirium by upsetting the balance of neurotransmitter synthesis, release, and inactivation. |
2022-09-09 |
2023-08-14 |
Not clear |
| Angeliki Zarkali, Andrea I Luppi, Emmanuel A Stamatakis, Suzanne Reeves, Peter McColgan, Louise-Ann Leyland, Andrew J Lees, Rimona S Wei. Changes in dynamic transitions between integrated and segregated states underlie visual hallucinations in Parkinson's disease. Communications biology. vol 5. issue 1. 2022-09-08. PMID:36075964. |
the regional energy needed for this transition was correlated with regional neurotransmitter density and gene expression for serotoninergic, gabaergic, noradrenergic and cholinergic, but not dopaminergic, receptors. |
2022-09-08 |
2023-08-14 |
Not clear |
| Elena E Vaiman, Natalia A Shnayder, Aiperi K Khasanova, Anna I Strelnik, Arseny J Gayduk, Mustafa Al-Zamil, Margarita R Sapronova, Natalia G Zhukova, Daria A Smirnova, Regina F Nasyrov. Pathophysiological Mechanisms of Antipsychotic-Induced Parkinsonism. Biomedicines. vol 10. issue 8. 2022-08-26. PMID:36009557. |
one of the causes of dip is the disruption of neurotransmitter interactions that regulate the signaling pathways of the dopaminergic, cholinergic, gabaergic, adenosinergic, endocannabinoid, and other neurotransmitter systems. |
2022-08-26 |
2023-08-14 |
Not clear |
| Yasir Hasan Siddique, Falaq Naz, Rahul, Himanshi Varshne. Comparative study of rivastigmine and galantamine on the transgenic Current research in pharmacology and drug discovery. vol 3. 2022-08-22. PMID:35992376. |
the accumulation of amyloid plaques and neurofibrillary tangles leads to the loss of neurons including the cholinergic neurons thus decreasing the levels of acetylcholine (a neurotransmitter). |
2022-08-22 |
2023-08-14 |
Not clear |
| Cyril Lhopitallier, Charlotte Perrault, Frédéric Chauveau, Françoise Saurini, Sylvie Berrard, Sylvie Granon, Alexis Faur. Characterization of social behavior in young and middle-aged ChAT-IRES-Cre mouse. PloS one. vol 17. issue 8. 2022-08-04. PMID:35925937. |
however, these data were obtained in mutant mice that also present alterations of several neurotransmitter systems, in addition to the cholinergic system. |
2022-08-04 |
2023-08-14 |
mouse |
| Correction to: Cholinergic neurotransmitter system: a potential marker for post-stroke cognitive recovery. Brain : a journal of neurology. 2022-08-02. PMID:35918789. |
correction to: cholinergic neurotransmitter system: a potential marker for post-stroke cognitive recovery. |
2022-08-02 |
2023-08-14 |
Not clear |
| Wenchao Li, Chun Zhang, Yang Yang Wang, Lifei Xiao, Yan Feng, Xianhao Huo, Chaofan Wang, Yu Sun, Feng Wang, Tao Su. Alterations of RNAs in the insula related to cocaine-induced condition place preference in adolescent mice. Biochemical and biophysical research communications. vol 621. 2022-07-12. PMID:35820280. |
a total of 198 differentially expressed genes (deg) that functioned in synaptic transmission, cholinergic, developmental process, neurotransmitter metabolic process, drug catabolism, cellular response to drug, map kinase activity, ceramidase activity, and drug resistance were significantly enriched. |
2022-07-12 |
2023-08-14 |
mouse |