Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
Toshiyasu Matsui, Takahiro Nakata, Yasushi Kobayash. Localization of organic cation transporter 2 (OCT2) in monoaminergic and cholinergic axon terminals of the mouse brain. Neuroscience letters. vol 633. 2017-07-27. PMID:27651065. |
together, our results demonstrated that the polyspecific cation transporter oct2 is distributed in cholinergic and monoaminergic terminals in various forebrain regions, suggesting that oct2 could play a role in regulating presynaptic reuptake and recycling of choline and monoamines. |
2017-07-27 |
2023-08-13 |
mouse |
L Aloe, M L Rocco, E Stigliano, F Angelini, M Iacoangeli, V Frari, F Salvinell. Nasal HPpSIS administration enhances NGF and tumor suppressor protein, p73 in human brain cancer tissues: preliminary data. European review for medical and pharmacological sciences. vol 21. issue 3. 2017-07-26. PMID:28239803. |
we have recently reported that nasal administration of high-pressure isotonic physiological saline solution (hppsis) enhances the level of ngf and the expression of ngf receptors in neurons of the olfactory bulbs and forebrain cholinergic neurons of laboratory animals. |
2017-07-26 |
2023-08-13 |
human |
Tristan Hedrick, Bethanny Danskin, Rylan S Larsen, Doug Ollerenshaw, Peter Groblewski, Matthew Valley, Shawn Olsen, Jack Water. Characterization of Channelrhodopsin and Archaerhodopsin in Cholinergic Neurons of Cre-Lox Transgenic Mice. PloS one. vol 11. issue 5. 2017-07-18. PMID:27243816. |
in most mice from these crosses, we observed expression of chr2 and arch in only cholinergic neurons in the basal forebrain and in other putative cholinergic neurons in the forebrain. |
2017-07-18 |
2023-08-13 |
mouse |
Richard L Dot. Olfactory dysfunction in neurodegenerative diseases: is there a common pathological substrate? The Lancet. Neurology. vol 16. issue 6. 2017-06-30. PMID:28504111. |
for example, the amount of damage to forebrain neurotransmitter and neuromodulator circuits, most notably those involving cholinergic transmission, appears to be correlated with quantitative smell test scores across a wide range of neurodegenerative diseases. |
2017-06-30 |
2023-08-13 |
Not clear |
Kathryn C Allaway, Robert Machol. Developmental specification of forebrain cholinergic neurons. Developmental biology. vol 421. issue 1. 2017-06-06. PMID:27847324. |
developmental specification of forebrain cholinergic neurons. |
2017-06-06 |
2023-08-13 |
Not clear |
Kathryn C Allaway, Robert Machol. Developmental specification of forebrain cholinergic neurons. Developmental biology. vol 421. issue 1. 2017-06-06. PMID:27847324. |
striatal cholinergic interneurons and basal forebrain cholinergic projection neurons, which together comprise the forebrain cholinergic system, regulate attention, memory, reward pathways, and motor activity through the neuromodulation of multiple brain circuits. |
2017-06-06 |
2023-08-13 |
Not clear |
Kathryn C Allaway, Robert Machol. Developmental specification of forebrain cholinergic neurons. Developmental biology. vol 421. issue 1. 2017-06-06. PMID:27847324. |
all forebrain cholinergic projection neurons and interneurons appear to share a common developmental origin in the embryonic ventral telencephalon, a region that also gives rise to gabaergic projection neurons and interneurons. |
2017-06-06 |
2023-08-13 |
Not clear |
N K Isaev, E V Stelmashook, E E Genrikh. Role of Nerve Growth Factor in Plasticity of Forebrain Cholinergic Neurons. Biochemistry. Biokhimiia. vol 82. issue 3. 2017-03-22. PMID:28320270. |
role of nerve growth factor in plasticity of forebrain cholinergic neurons. |
2017-03-22 |
2023-08-13 |
Not clear |
Maria Florencia Iulita, Filippo Caraci, Augusto Claudio Cuell. A Link Between Nerve Growth Factor Metabolic Deregulation and Amyloid-β-Driven Inflammation in Down Syndrome. CNS & neurological disorders drug targets. vol 15. issue 4. 2016-12-30. PMID:26996175. |
in the mature and fully differentiated central nervous system, the phenotype of forebrain cholinergic neurons and their nerve terminals in cortex and hippocampus depend on the continuous endogenous supply of nerve growth factor (ngf). |
2016-12-30 |
2023-08-13 |
Not clear |
Marzia Soligo, Virginia Protto, Fulvio Florenzano, Luisa Bracci-Laudiero, Fabrizio De Benedetti, Antonio Chiaretti, Luigi Mann. The mature/pro nerve growth factor ratio is decreased in the brain of diabetic rats: Analysis by ELISA methods. Brain research. vol 1624. 2016-08-10. PMID:26282349. |
nerve growth factor (ngf) is essential for the survival and functional maintenance of forebrain cholinergic neurons projecting mainly to the cortex and hippocampus. |
2016-08-10 |
2023-08-13 |
human |
Luigi Aloe, Maria Luisa Rocco, Bijorn Omar Balzamino, Alessandra Micer. Nerve Growth Factor: A Focus on Neuroscience and Therapy. Current neuropharmacology. vol 13. issue 3. 2016-08-09. PMID:26411962. |
nerve growth factor (ngf) is the firstly discovered and best characterized neurotrophic factor, known to play a critical protective role in the development and survival of sympathetic, sensory and forebrain cholinergic neurons. |
2016-08-09 |
2023-08-13 |
human |
Hanna Bielarczyk, Agnieszka Jankowska-Kulawy, Corinna Höfling, Anna Ronowska, Sylwia Gul-Hinc, Steffen Roßner, Reinhard Schliebs, Tadeusz Pawelczyk, Andrzej Szutowic. AβPP-Transgenic 2576 Mice Mimic Cell Type-Specific Aspects of Acetyl-CoA-Linked Metabolic Deficits in Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 48. issue 4. 2016-08-03. PMID:26402099. |
activities of pyruvate dehydrogenase complex, choline acetyltransferase, and several enzymes of acetyl-coa and energy metabolism were found to be unchanged in both forebrain mitochondria and synaptosomes of tg2576 mice, indicating preservation of structural integrity at least in cholinergic neuronal cells. |
2016-08-03 |
2023-08-13 |
mouse |
Stefan M Brudzynsk. Pharmacology of Ultrasonic Vocalizations in adult Rats: Significance, Call Classification and Neural Substrate. Current neuropharmacology. vol 13. issue 2. 2016-07-06. PMID:26411761. |
negative emotional states are associated with emission of 22 khz vocalizations that could be induced by aversive situations, muscarinic cholinergic activation of limbic areas of medial diencephalon and forebrain, and are mediated by m2 muscarinic receptors. |
2016-07-06 |
2023-08-13 |
rat |
H Scott Swartzwelder, Shawn K Acheson, Kelsey M Miller, Hannah G Sexton, Wen Liu, Fulton T Crews, Mary-Louise Rishe. Adolescent Intermittent Alcohol Exposure: Deficits in Object Recognition Memory and Forebrain Cholinergic Markers. PloS one. vol 10. issue 11. 2016-06-17. PMID:26529506. |
adolescent intermittent alcohol exposure: deficits in object recognition memory and forebrain cholinergic markers. |
2016-06-17 |
2023-08-13 |
rat |
H Scott Swartzwelder, Shawn K Acheson, Kelsey M Miller, Hannah G Sexton, Wen Liu, Fulton T Crews, Mary-Louise Rishe. Adolescent Intermittent Alcohol Exposure: Deficits in Object Recognition Memory and Forebrain Cholinergic Markers. PloS one. vol 10. issue 11. 2016-06-17. PMID:26529506. |
a separate group of animals was used to assess the density of cholinergic neurons in forebrain areas ch1-4 using immunohistochemistry. |
2016-06-17 |
2023-08-13 |
rat |
Armin Raznahan, YanHe Lue, Frank Probst, Deanna Greenstein, Jay Giedd, Christina Wang, Jason Lerch, Ronald Swerdlof. Triangulating the sexually dimorphic brain through high-resolution neuroimaging of murine sex chromosome aneuploidies. Brain structure & function. vol 220. issue 6. 2016-06-15. PMID:25146308. |
we then harness anatomical variation across all four karyotype groups in our study--xo, xx, xy and xxy--to create an agnostic data-driven segmentation of the mouse brain into five distributed clusters which (1) recover fundamental properties of brain organization with high spatial precision, (2) define two previously uncharacterized systems of relative volume excess in females vs. males ("forebrain cholinergic" and "cerebelo-pontine-thalamo-cortical"), and (3) adopt stereotyped spatial motifs which delineate ordered gradients of sex chromosome and gonadal influences on volumetric brain development. |
2016-06-15 |
2023-08-13 |
mouse |
b' Ra\\xc3\\xbal Pe\\xc3\\xb1as-Cazorla, M Teresa Vilar\\xc3\\xb. Serotonin 5-HT4 receptors and forebrain cholinergic system: receptor expression in identified cell populations. Brain structure & function. vol 220. issue 6. 2016-06-15. PMID:25183542.' |
serotonin 5-ht4 receptors and forebrain cholinergic system: receptor expression in identified cell populations. |
2016-06-15 |
2023-08-13 |
rat |
Bin Liu, Carrie H Croy, Stephen A Hitchcock, Jennifer R Allen, Zhigang Rao, David Evans, Mark G Bures, David L McKinzie, Marla Leigh Watt, G Stuart Gregory, Marvin M Hansen, Paul J Hoogestraat, James A Jamison, Fese M Okha-Mokube, Robert E Stratford, William Turner, Frank Bymaster, Christian C Felde. Design and synthesis of N-[6-(Substituted Aminoethylideneamino)-2-Hydroxyindan-1-yl]arylamides as selective and potent muscarinic M₁ agonists. Bioorganic & medicinal chemistry letters. vol 25. issue 19. 2016-05-24. PMID:26299349. |
the observation that cholinergic deafferentation of circuits projecting from forebrain basal nuclei to frontal and hippocampal circuits occurs in alzheimer's disease has led to drug-targeting of muscarinic m1 receptors to alleviate cognitive symptoms. |
2016-05-24 |
2023-08-13 |
Not clear |
Matteo Fornai, Carolina Pellegrini, Luca Antonioli, Cristina Segnani, Chiara Ippolito, Elisabetta Barocelli, Vigilio Ballabeni, Gaia Vegezzi, Zainab Al Harraq, Fabio Blandini, Giovanna Levandis, Silvia Cerri, Corrado Blandizzi, Nunzia Bernardini, Rocchina Colucc. Enteric Dysfunctions in Experimental Parkinson's Disease: Alterations of Excitatory Cholinergic Neurotransmission Regulating Colonic Motility in Rats. The Journal of pharmacology and experimental therapeutics. vol 356. issue 2. 2016-05-06. PMID:26582732. |
this study examined the impact of central dopaminergic denervation, induced by injection of 6-hydroxydopamine (6-ohda) into the medial forebrain bundle, on distal colonic excitatory cholinergic neuromotor activity in rats. |
2016-05-06 |
2023-08-13 |
rat |
Daniel Bertrand, Chih-Hung L Lee, Dorothy Flood, Fabrice Marger, Diana Donnelly-Robert. Therapeutic Potential of α7 Nicotinic Acetylcholine Receptors. Pharmacological reviews. vol 67. issue 4. 2016-05-04. PMID:26419447. |
progress in the fields of neuroscience and molecular biology has identified the forebrain cholinergic system as being important in many higher order brain functions. |
2016-05-04 |
2023-08-13 |
human |