| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Maria Eriksdotter, Sumonto Mitr. Gene and cell therapy for the nucleus basalis of Meynert with NGF in Alzheimer's disease. Handbook of clinical neurology. vol 179. 2021-07-28. PMID:34225964. |
since there is a lack of ngf and its receptors in the ad forebrain, the hypothesis is that local delivery of ngf to the nbm could revive the cholinergic circuitry and thereby restore cognitive functions. |
2021-07-28 |
2023-08-13 |
Not clear |
| Nicole E Chambers, Michael Coyle, Jordan Sergio, Kathryn Lanza, Carolyn Saito, Brent Topping, Stewart D Clark, Christopher Bisho. Effects of pedunculopontine nucleus cholinergic lesion on gait and dyskinesia in hemiparkinsonian rats. The European journal of neuroscience. vol 53. issue 8. 2021-06-30. PMID:33426708. |
sprague-dawley rats were assigned to one unilaterally lesioned group: sham lesion, ppn cholinergic lesion with diphtheria urotensin ii fusion toxin, medial forebrain bundle dopamine lesion with 6-hydroxydopamine, or dual acetylcholine and dopamine lesion. |
2021-06-30 |
2023-08-13 |
rat |
| Rok Berlot, Zvezdan Pirtošek, Simon Brezovar, Blaž Koritnik, Stefan J Teipel, Michel J Grothe, Nicola J Ra. Cholinergic basal forebrain and hippocampal structure influence visuospatial memory in Parkinson's disease. Brain imaging and behavior. 2021-06-27. PMID:34176042. |
these findings are consistent with the recent hypothesis that forebrain cholinergic system degeneration results in cognitive deficits via cholinergic denervation, and subsequent structural degeneration, of its target regions. |
2021-06-27 |
2023-08-13 |
Not clear |
| Rok Berlot, Blaž Koritnik, Zvezdan Pirtošek, Nicola J Ra. Preserved cholinergic forebrain integrity reduces structural connectome vulnerability in mild cognitive impairment. Journal of the neurological sciences. vol 425. 2021-05-25. PMID:33865078. |
preserved cholinergic forebrain integrity reduces structural connectome vulnerability in mild cognitive impairment. |
2021-05-25 |
2023-08-13 |
Not clear |
| Kathryn C Allaway, William Muñoz, Robin Tremblay, Mia Sherer, Jacob Herron, Bernardo Rudy, Robert Machold, Gordon Fishel. Cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain. eLife. vol 9. 2021-03-18. PMID:33355093. |
cellular birthdate predicts laminar and regional cholinergic projection topography in the forebrain. |
2021-03-18 |
2023-08-13 |
mouse |
| Elena I Zakharova, Zinaida I Storozheva, Andrey T Proshin, Mikhail Yu Monakov, Alexander M Dudchenk. Opposite Pathways of Cholinergic Mechanisms of Hypoxic Preconditioning in the Hippocampus: Participation of Nicotinic α7 Receptors and Their Association with the Baseline Level of Startle Prepulse Inhibition. Brain sciences. vol 11. issue 1. 2021-01-26. PMID:33374246. |
(5) conclusion: we substantiate that in rats with low and high ppi two opposite hippocampal cholinergic mechanisms are involved in hypoxic preconditioning, and both are implemented by forebrain projections via nicotinic α7 receptors. |
2021-01-26 |
2023-08-13 |
rat |
| Elena I Zakharova, Zinaida I Storozheva, Andrey T Proshin, Mikhail Yu Monakov, Alexander M Dudchenk. Opposite Pathways of Cholinergic Mechanisms of Hypoxic Preconditioning in the Hippocampus: Participation of Nicotinic α7 Receptors and Their Association with the Baseline Level of Startle Prepulse Inhibition. Brain sciences. vol 11. issue 1. 2021-01-26. PMID:33374246. |
possible causes of association between general protective adaptation, hbh, ppi, forebrain cholinergic system and hippocampus are discussed. |
2021-01-26 |
2023-08-13 |
rat |
| Ricardo Nitrin. Rationale for launching a new journa. Dementia & neuropsychologia. vol 1. issue 1. 2020-10-01. PMID:29213360. |
the acquisition of data on the anatomy of the cholinergic pathways, including the localization of the nuclei of the basal prosencephalon and the routes of their projections, established an important milestone. |
2020-10-01 |
2023-08-13 |
human |
| Eliasz Engelhardt, Denise Madeira Moreira, Jerson Lak. Vascular dementia and the cholinergic pathways. Dementia & neuropsychologia. vol 1. issue 1. 2020-10-01. PMID:29213361. |
the acquisition of data on the anatomy of the cholinergic pathways, including the localization of the nuclei of the basal prosencephalon and the routes of their projections, established an important milestone. |
2020-10-01 |
2023-08-13 |
human |
| Kurt R Lehner, Harold A Silverman, Meghan E Addorisio, Ashbeel Roy, Mohammed A Al-Onaizi, Yaakov Levine, Peder S Olofsson, Sangeeta S Chavan, Robert Gros, Neil M Nathanson, Yousef Al-Abed, Christine N Metz, Vania F Prado, Marco A M Prado, Kevin J Tracey, Valentin A Pavlo. Forebrain Cholinergic Signaling Regulates Innate Immune Responses and Inflammation. Frontiers in immunology. vol 10. 2020-09-24. PMID:31024522. |
forebrain cholinergic signaling regulates innate immune responses and inflammation. |
2020-09-24 |
2023-08-13 |
mouse |
| Kurt R Lehner, Harold A Silverman, Meghan E Addorisio, Ashbeel Roy, Mohammed A Al-Onaizi, Yaakov Levine, Peder S Olofsson, Sangeeta S Chavan, Robert Gros, Neil M Nathanson, Yousef Al-Abed, Christine N Metz, Vania F Prado, Marco A M Prado, Kevin J Tracey, Valentin A Pavlo. Forebrain Cholinergic Signaling Regulates Innate Immune Responses and Inflammation. Frontiers in immunology. vol 10. 2020-09-24. PMID:31024522. |
here, utilizing selective genetic and pharmacological approaches, we studied the role of forebrain cholinergic signaling in the regulation of peripheral immune function and inflammation. |
2020-09-24 |
2023-08-13 |
mouse |
| Kurt R Lehner, Harold A Silverman, Meghan E Addorisio, Ashbeel Roy, Mohammed A Al-Onaizi, Yaakov Levine, Peder S Olofsson, Sangeeta S Chavan, Robert Gros, Neil M Nathanson, Yousef Al-Abed, Christine N Metz, Vania F Prado, Marco A M Prado, Kevin J Tracey, Valentin A Pavlo. Forebrain Cholinergic Signaling Regulates Innate Immune Responses and Inflammation. Frontiers in immunology. vol 10. 2020-09-24. PMID:31024522. |
these findings reveal that forebrain cholinergic neurons regulate innate immune responses and inflammation, suggesting the possibility that in diseases associated with cholinergic dysfunction, including alzheimer's disease this anti-inflammatory regulation can be impaired. |
2020-09-24 |
2023-08-13 |
mouse |
| Kurt R Lehner, Harold A Silverman, Meghan E Addorisio, Ashbeel Roy, Mohammed A Al-Onaizi, Yaakov Levine, Peder S Olofsson, Sangeeta S Chavan, Robert Gros, Neil M Nathanson, Yousef Al-Abed, Christine N Metz, Vania F Prado, Marco A M Prado, Kevin J Tracey, Valentin A Pavlo. Forebrain Cholinergic Signaling Regulates Innate Immune Responses and Inflammation. Frontiers in immunology. vol 10. 2020-09-24. PMID:31024522. |
these results also suggest novel anti-inflammatory approaches based on targeting forebrain cholinergic signaling in sepsis and other disorders characterized by immune dysregulation. |
2020-09-24 |
2023-08-13 |
mouse |
| Martin Sarter, Cindy Lusti. Forebrain Cholinergic Signaling: Wired and Phasic, Not Tonic, and Causing Behavior. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 4. 2020-07-23. PMID:31969489. |
forebrain cholinergic signaling: wired and phasic, not tonic, and causing behavior. |
2020-07-23 |
2023-08-13 |
Not clear |
| Tímea Téglás, Zoltán Németh, Ákos Koller, Eddy A Van der Zee, Paul G M Luiten, Csaba Nyaka. Effects of Long-Term Moderate Intensity Exercise on Cognitive Behaviors and Cholinergic Forebrain in the Aging Rat. Neuroscience. vol 411. 2020-02-04. PMID:31146009. |
effects of long-term moderate intensity exercise on cognitive behaviors and cholinergic forebrain in the aging rat. |
2020-02-04 |
2023-08-13 |
rat |
| Tímea Téglás, Zoltán Németh, Ákos Koller, Eddy A Van der Zee, Paul G M Luiten, Csaba Nyaka. Effects of Long-Term Moderate Intensity Exercise on Cognitive Behaviors and Cholinergic Forebrain in the Aging Rat. Neuroscience. vol 411. 2020-02-04. PMID:31146009. |
since learning and memory are closely associated with cholinergic forebrain function chat fiber density after exercise training was assessed in hippocampus, and motor- and somatosensory cortical areas. |
2020-02-04 |
2023-08-13 |
rat |
| Tímea Téglás, Zoltán Németh, Ákos Koller, Eddy A Van der Zee, Paul G M Luiten, Csaba Nyaka. Effects of Long-Term Moderate Intensity Exercise on Cognitive Behaviors and Cholinergic Forebrain in the Aging Rat. Neuroscience. vol 411. 2020-02-04. PMID:31146009. |
in conclusion, chronic exercise attenuates the age-related decline in cognitive and motor behaviors as well as age-related cholinergic fiber reduction, reduces malformations of cholinergic forebrain innervation. |
2020-02-04 |
2023-08-13 |
rat |
| Lukas Scheef, Michel J Grothe, Alexander Koppara, Marcel Daamen, Henning Boecker, Hans Biersack, Hans H Schild, Michael Wagner, Stefan Teipel, Frank Jesse. Subregional volume reduction of the cholinergic forebrain in subjective cognitive decline (SCD). NeuroImage. Clinical. vol 21. 2019-12-11. PMID:30555006. |
subregional volume reduction of the cholinergic forebrain in subjective cognitive decline (scd). |
2019-12-11 |
2023-08-13 |
human |
| H. Hodges, S. Thrasher, J.A. Gra. Improved radial maze performance induced by the benzodiazepine antagonist ZK 93 426 in lesioned and alcohol-treated rats. Behavioural pharmacology. vol 1. issue 1. 2019-11-20. PMID:11175386. |
effects of the benzodiazepine receptor antagonist zk 93 426 were examined in two groups of rats with long lasting radial maze impairments caused by either ibotenic acid lesions to cholinergic forebrain projections or 28 weeks of alcohol treatment. |
2019-11-20 |
2023-08-12 |
rat |
| G.A. Grigoryan, J.A. Gray, T. Rashid, A. Chadwick, H. Hodge. Conditionally immortal neuroepithelial stem cell grafts restore spatial learning in rats with lesions at the source of cholinergic forebrain projections cholinergic forebrain projections Conditionally immortal neuroepithelial stem cell grafts restore spatial leaming in rats with lesions at the source of cholinergic forebrain projections. Restorative neurology and neuroscience. vol 17. issue 4. 2019-11-20. PMID:11490086. |
conditionally immortal neuroepithelial stem cell grafts restore spatial learning in rats with lesions at the source of cholinergic forebrain projections cholinergic forebrain projections conditionally immortal neuroepithelial stem cell grafts restore spatial leaming in rats with lesions at the source of cholinergic forebrain projections. |
2019-11-20 |
2023-08-12 |
human |