| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hyong-Ho Cho, Francesca Cargnin, Yujin Kim, Bora Lee, Ryuk-Jun Kwon, Heejin Nam, Rongkun Shen, Anthony P Barnes, Jae W Lee, Seunghee Lee, Soo-Kyung Le. Isl1 directly controls a cholinergic neuronal identity in the developing forebrain and spinal cord by forming cell type-specific complexes. PLoS genetics. vol 10. issue 4. 2014-11-24. PMID:24763339. |
here, we investigated the gene regulatory networks that specify the cholinergic neuronal fates in the spinal cord and forebrain, specifically, spinal motor neurons (mns) and forebrain cholinergic neurons (fcns). |
2014-11-24 |
2023-08-13 |
Not clear |
| Hyong-Ho Cho, Francesca Cargnin, Yujin Kim, Bora Lee, Ryuk-Jun Kwon, Heejin Nam, Rongkun Shen, Anthony P Barnes, Jae W Lee, Seunghee Lee, Soo-Kyung Le. Isl1 directly controls a cholinergic neuronal identity in the developing forebrain and spinal cord by forming cell type-specific complexes. PLoS genetics. vol 10. issue 4. 2014-11-24. PMID:24763339. |
conditional inactivation of isl1, a lim homeodomain factor expressed in both differentiating mns and fcns, led to a drastic loss of cholinergic neurons in the developing spinal cord and forebrain. |
2014-11-24 |
2023-08-13 |
Not clear |
| Hyong-Ho Cho, Francesca Cargnin, Yujin Kim, Bora Lee, Ryuk-Jun Kwon, Heejin Nam, Rongkun Shen, Anthony P Barnes, Jae W Lee, Seunghee Lee, Soo-Kyung Le. Isl1 directly controls a cholinergic neuronal identity in the developing forebrain and spinal cord by forming cell type-specific complexes. PLoS genetics. vol 10. issue 4. 2014-11-24. PMID:24763339. |
similarly, in the developing forebrain, the isl1-lhx8-hexamer was recruited to the cholinergic gene battery and promoted cholinergic gene expression. |
2014-11-24 |
2023-08-13 |
Not clear |
| Hyong-Ho Cho, Francesca Cargnin, Yujin Kim, Bora Lee, Ryuk-Jun Kwon, Heejin Nam, Rongkun Shen, Anthony P Barnes, Jae W Lee, Seunghee Lee, Soo-Kyung Le. Isl1 directly controls a cholinergic neuronal identity in the developing forebrain and spinal cord by forming cell type-specific complexes. PLoS genetics. vol 10. issue 4. 2014-11-24. PMID:24763339. |
together, our studies show a shared molecular mechanism that determines the cholinergic neuronal fate in the spinal cord and forebrain, and uncover an important gene regulatory mechanism that directs a specific neurotransmitter identity in vertebrate cns development. |
2014-11-24 |
2023-08-13 |
Not clear |
| Sung Ho Jang, Hyeok Gyu Kwo. Perspectives on the neural connectivity of the fornix in the human brain. Neural regeneration research. vol 9. issue 15. 2014-10-15. PMID:25317154. |
the anterior fornical body has high connectivity with the anterior commissure, and brain areas relevant to cholinergic nuclei (septal forebrain region and brainstem) and memory function (medial temporal lobe). |
2014-10-15 |
2023-08-13 |
human |
| Xiao-rui Cheng, Wen-xia Zhou, Yong-xiang Zhan. The behavioral, pathological and therapeutic features of the senescence-accelerated mouse prone 8 strain as an Alzheimer's disease animal model. Ageing research reviews. vol 13. 2014-10-14. PMID:24269312. |
many studies indicate that samp8 mice harbor the behavioral and histopathological signatures of ad, namely ad-like cognitive and behavioral alterations, neuropathological phenotypes (neuron and dendrite spine loss, spongiosis, gliosis and cholinergic deficits in the forebrain), β-amyloid deposits resembling senile plaques, and aberrant hyperphosphorylation of tau-like neurofibrillary tangles. |
2014-10-14 |
2023-08-12 |
mouse |
| Sung Ho Jang, Hyeok Gyu Kwo. Neural connectivity of the anterior body of the fornix in the human brain: diffusion tensor imaging study. Neuroscience letters. vol 559. 2014-09-28. PMID:24304866. |
the anterior body of the fornix showed high connectivity with the anterior commissure and hypothalamus, and brain areas relevant to cholinergic nuclei (the septal forebrain region and brainstem) and memory function (the medial temporal lobe). |
2014-09-28 |
2023-08-12 |
human |
| Nicolaas I Bohnen, Klaus Jah. Imaging: What can it tell us about parkinsonian gait? Movement disorders : official journal of the Movement Disorder Society. vol 28. issue 11. 2014-05-19. PMID:24132837. |
for example, our preliminary cholinergic imaging studies suggest significant slowing of gait speed when additional forebrain cholinergic denervation occurs in pd. |
2014-05-19 |
2023-08-12 |
Not clear |
| Paweł Matulewicz, Magda Kuśmierczak, Jolanta Orzeł-Gryglewska, Edyta Jurkowlanie. Hippocampal theta rhythm induced by rostral pontine nucleus stimulation in the conditions of pedunculopontine tegmental nucleus inactivation. Brain research bulletin. vol 96. 2014-03-19. PMID:23632212. |
the multi-level regulatory system of theta, based mainly on cholinergic transmission, includes structures from the forebrain to the medulla. |
2014-03-19 |
2023-08-12 |
rat |
| Mohammed Zacky Ariffin, Lai Seong Chang, Han Chow Koh, Chian-Ming Low, Sanjay Khann. An environment-dependent modulation of cortical neural response by forebrain cholinergic neurons in awake rat. Brain research. vol 1513. 2013-12-16. PMID:23562704. |
an environment-dependent modulation of cortical neural response by forebrain cholinergic neurons in awake rat. |
2013-12-16 |
2023-08-12 |
rat |
| Mohammed Zacky Ariffin, Lai Seong Chang, Han Chow Koh, Chian-Ming Low, Sanjay Khann. An environment-dependent modulation of cortical neural response by forebrain cholinergic neurons in awake rat. Brain research. vol 1513. 2013-12-16. PMID:23562704. |
the forebrain cholinergic neurons project to cortex, including the hippocampus and the cingulate cortex (cg). |
2013-12-16 |
2023-08-12 |
rat |
| Mohammed Zacky Ariffin, Lai Seong Chang, Han Chow Koh, Chian-Ming Low, Sanjay Khann. An environment-dependent modulation of cortical neural response by forebrain cholinergic neurons in awake rat. Brain research. vol 1513. 2013-12-16. PMID:23562704. |
we have now examined the effect of destruction of the cholinergic neurons with microinjection of the immunotoxin 192 igg-saporin into the medial septum on the induction of c-fos protein, an index of neuronal synaptic excitation, in the two forebrain areas to varied episodic experiences. |
2013-12-16 |
2023-08-12 |
rat |
| Mohammed Zacky Ariffin, Lai Seong Chang, Han Chow Koh, Chian-Ming Low, Sanjay Khann. An environment-dependent modulation of cortical neural response by forebrain cholinergic neurons in awake rat. Brain research. vol 1513. 2013-12-16. PMID:23562704. |
these findings suggest that the cholinergic modulation of the neural processing in the two forebrain areas varies partly in an environment-dependent fashion affecting ca1 neural activation on repeat exposure to an environment where they had a relatively complex aversive experience while favoring cg neural activation more during novelty. |
2013-12-16 |
2023-08-12 |
rat |
| Mohammad Reza Sepand, Maliheh Soodi, Homa Hajimehdipoor, Masoud Soleimani, Ehsan Sahrae. Comparison of Neuroprotective Effects of Melissa officinalis Total Extract and Its Acidic and Non-Acidic Fractions against A β-Induced Toxicity. Iranian journal of pharmaceutical research : IJPR. vol 12. issue 2. 2013-11-19. PMID:24250617. |
oxidative damage to neurons and loss of cholinergic neurons in forebrain region are observed in this disease. |
2013-11-19 |
2023-08-12 |
Not clear |
| Hayat Harati, Alexandra Barbelivien, Karine Herbeaux, Marc-Antoine Muller, Michel Engeln, Christian Kelche, Jean-Christophe Cassel, Monique Majchrza. Lifelong environmental enrichment in rats: impact on emotional behavior, spatial memory vividness, and cholinergic neurons over the lifespan. Age (Dordrecht, Netherlands). vol 35. issue 4. 2013-10-17. PMID:22592932. |
we assessed lifelong environmental enrichment effects on possible age-related modifications in emotional behaviors, spatial memory acquisition, retrieval of recent and remote spatial memory, and cholinergic forebrain systems. |
2013-10-17 |
2023-08-12 |
rat |
| A N Mamelak, J A Hobso. Dream Bizarreness as the Cognitive Correlate of Altered Neuronal Behavior in REM Sleep. Journal of cognitive neuroscience. vol 1. issue 3. 2013-08-26. PMID:23968505. |
these bifurcations are caused by phasic discharge of pontogeniculooccipital (pgo) neurons during rem sleep, providing a source of cholinergic modulation to the forebrain which could evoke unpredictable network responses. |
2013-08-26 |
2023-08-12 |
Not clear |
| Michel Grothe, Helmut Heinsen, Stefan Teipe. Longitudinal measures of cholinergic forebrain atrophy in the transition from healthy aging to Alzheimer's disease. Neurobiology of aging. vol 34. issue 4. 2013-08-01. PMID:23158764. |
longitudinal measures of cholinergic forebrain atrophy in the transition from healthy aging to alzheimer's disease. |
2013-08-01 |
2023-08-12 |
human |
| Navzer D Engineer, Aage R Møller, Michael P Kilgar. Directing neural plasticity to understand and treat tinnitus. Hearing research. vol 295. 2013-06-24. PMID:23099209. |
the forebrain cholinergic system and the noradrenergic system play a significant role in modulating cortical plasticity. |
2013-06-24 |
2023-08-12 |
rat |
| Lin Feng, Evgeny A Sametsky, Alexander G Gusev, Victor V Uteshe. Responsiveness to nicotine of neurons of the caudal nucleus of the solitary tract correlates with the neuronal projection target. Journal of neurophysiology. vol 108. issue 7. 2013-06-14. PMID:22815399. |
the pbn integrates and relays viscerosensory information primarily to the forebrain, supporting behavioral, emotional, and endocrine responses to visceral events, while the dmv contains parasympathetic preganglionic cholinergic motoneurons that support primarily gastrointestinal reflexes. |
2013-06-14 |
2023-08-12 |
Not clear |
| Nicholas D Leach, Fernando R Nodal, Patricia M Cordery, Andrew J King, Victoria M Baj. Cortical cholinergic input is required for normal auditory perception and experience-dependent plasticity in adult ferrets. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 15. 2013-06-05. PMID:23575862. |
ferrets with cholinergic forebrain lesions were also less able to relearn to localize sound after plugging one ear. |
2013-06-05 |
2023-08-12 |
Not clear |