| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D M Michaelson, V Dubovik, M Faigon, D Eilam, J Feldo. Decreased density of forebrain cholinergic neurons and disintegration of the spatial organization of behavior in experimental autoimmune dementia (EAD). Annals of the New York Academy of Sciences. vol 695. 1993-12-10. PMID:8239291. |
the results obtained show that production in ead rats of anti-cholinergic nf-h abs similar to those found in ad patients results in a marked decrease in the density of forebrain cholinergic neurons and in derangements in the spatio-temporal organization of their behavior. |
1993-12-10 |
2023-08-12 |
rat |
| M Fusco, G Vantini, N Schiavo, A Zanotti, R Zanoni, L Facci, S D Skape. Gangliosides and neurotrophic factors in neurodegenerative diseases: from experimental findings to clinical perspectives. Annals of the New York Academy of Sciences. vol 695. 1993-12-10. PMID:8239303. |
in particular, it has been demonstrated that nerve growth factor (ngf) exerts a physiological role for forebrain cholinergic neurons, while brain-derived neurotrophic factor (bdnf) seems to play a relevant role in rescuing dopaminergic neurons following damage. |
1993-12-10 |
2023-08-12 |
rat |
| M Fusco, G Vantini, N Schiavo, A Zanotti, R Zanoni, L Facci, S D Skape. Gangliosides and neurotrophic factors in neurodegenerative diseases: from experimental findings to clinical perspectives. Annals of the New York Academy of Sciences. vol 695. 1993-12-10. PMID:8239303. |
the responsiveness of forebrain cholinergic neurons following ngf +/- gm1 was evaluated by assessing choline acetyltransferase (chat) activity in hippocampus, septal area and striatum of behaviorally impaired 24-month-old rats. |
1993-12-10 |
2023-08-12 |
rat |
| V Dubovik, M Faigon, J Feldon, D M Michaelso. Decreased density of forebrain cholinergic neurons in experimental autoimmune dementia. Neuroscience. vol 56. issue 1. 1993-12-07. PMID:8232919. |
decreased density of forebrain cholinergic neurons in experimental autoimmune dementia. |
1993-12-07 |
2023-08-12 |
rat |
| V Dubovik, M Faigon, J Feldon, D M Michaelso. Decreased density of forebrain cholinergic neurons in experimental autoimmune dementia. Neuroscience. vol 56. issue 1. 1993-12-07. PMID:8232919. |
in the present study we examined whether the anti-cholinergic high molecular weight neurofilament subunit immune response of the experimental autoimmune dementia rats affects forebrain cholinergic neurons. |
1993-12-07 |
2023-08-12 |
rat |
| V Dubovik, M Faigon, J Feldon, D M Michaelso. Decreased density of forebrain cholinergic neurons in experimental autoimmune dementia. Neuroscience. vol 56. issue 1. 1993-12-07. PMID:8232919. |
this was performed immunohistochemically utilizing a monoclonal antibody to nerve growth factor receptor, a specific marker of cholinergic neurons in the forebrain. |
1993-12-07 |
2023-08-12 |
rat |
| V Dubovik, M Faigon, J Feldon, D M Michaelso. Decreased density of forebrain cholinergic neurons in experimental autoimmune dementia. Neuroscience. vol 56. issue 1. 1993-12-07. PMID:8232919. |
the decrease in density of forebrain cholinergic neurons in experimental autoimmune dementia rats may mimic pathogenic processes in alzheimer's disease and supports a role for anti-cholinergic high molecular weight neurofilament subunit antibodies in the degeneration of cholinergic neurons in the disease. |
1993-12-07 |
2023-08-12 |
rat |
| D Eilam, H Szechtman, M Faigon, V Dubovik, J Feldon, D M Michaelso. Disintegration of the spatial organization of behavior in experimental autoimmune dementia. Neuroscience. vol 56. issue 1. 1993-12-07. PMID:8232920. |
production of such antibodies in experimental autoimmune dementia rats by prolonged immunization with the torpedo cholinergic high molecular weight neurofilament subunit results in accumulation of antibodies in the septum and hippocampus of the immunized rats, in a marked decrease in the density of forebrain cholinergic neurons, and in memory deficits. |
1993-12-07 |
2023-08-12 |
rat |
| K G Bina, B Rusak, K Semb. Localization of cholinergic neurons in the forebrain and brainstem that project to the suprachiasmatic nucleus of the hypothalamus in rat. The Journal of comparative neurology. vol 335. issue 2. 1993-12-01. PMID:8227520. |
localization of cholinergic neurons in the forebrain and brainstem that project to the suprachiasmatic nucleus of the hypothalamus in rat. |
1993-12-01 |
2023-08-12 |
rat |
| J V Rosenfel. Current issues in neural transplantation. Annals of the Academy of Medicine, Singapore. vol 22. issue 3 Suppl. 1993-11-16. PMID:8215202. |
although foetal forebrain cholinergic and spinal grafts have been performed in animals, these have not yet been attempted for alzheimer's disease, or spinal cord damage respectively in humans. |
1993-11-16 |
2023-08-12 |
human |
| J K Morse, S J Wiegand, K Anderson, Y You, N Cai, J Carnahan, J Miller, P S DiStefano, C A Altar, R M Lindsa. Brain-derived neurotrophic factor (BDNF) prevents the degeneration of medial septal cholinergic neurons following fimbria transection. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 10. 1993-11-12. PMID:8080477. |
to substantiate a potential role for bdnf in the maintenance of forebrain cholinergic neurons in the adult brain, we assessed the ability of bdnf to sustain the phenotype of medial septal cholinergic neurons following a unilateral transection of the fimbria. |
1993-11-12 |
2023-08-12 |
rat |
| G Forloni, R Del Bo, N Angeretti, S Smiroldo, N Gabellini, G Vantin. Nerve growth factor does not influence the expression of beta amyloid precursor protein mRNA in rat brain: in vivo and in vitro studies. Brain research. vol 620. issue 2. 1993-10-14. PMID:8369961. |
these data indicate that the neurotrophic effect of ngf on forebrain cholinergic neurons is not always associated with an alteration of app expression. |
1993-10-14 |
2023-08-12 |
rat |
| K Tanaka, T Tamura, M Kawashima, S Ueda, Y Matsumoto, M Kawata, Y Ogino, T Yamamoto, H Honjo, H Okad. [The histochemical study of the effects of estrogen on the forebrain cholinergic neurons of fetal female rats transplanted into the anterior eye chamber of adult female rats]. Nihon Naibunpi Gakkai zasshi. vol 69. issue 5. 1993-08-18. PMID:8330655. |
[the histochemical study of the effects of estrogen on the forebrain cholinergic neurons of fetal female rats transplanted into the anterior eye chamber of adult female rats]. |
1993-08-18 |
2023-08-12 |
rat |
| M Calaminici, F A Abdulla, J D Sinden, J D Stephenso. Direct evidence for axonal outgrowth from cholinergic grafts to cholinergically-deafferented rat cortex. Neuroreport. vol 4. issue 5. 1993-07-22. PMID:7685643. |
true blue, a retrograde fluorescent tracer, was used to investigate axonal outgrowth after grafting embryonic forebrain cholinergic tissue into the cholinergically-deafferented rat frontal cortex. |
1993-07-22 |
2023-08-12 |
rat |
| M Takashima, M Takita, A Umino, T Nishikawa, H Mitsushio, K Takahash. Modulation of cerebral acetylcholine metabolism by the dorsal diencephalic conduction system in the rat. Neurochemistry international. vol 20. issue 4. 1993-07-15. PMID:1304873. |
these findings suggest that the dorsal diencephalic conduction system may be involved in the integration of the activity of cholinergic neurons in the forebrain and midbrain regions and striatal dopanine neurons may play a role in the modulation of cholinergic neurons. |
1993-07-15 |
2023-08-11 |
rat |
| O S Vinogradova, E S Brazhnik, V S Stafekhina, V F Kitchigin. Acetylcholine, theta-rhythm and activity of hippocampal neurons in the rabbit--II. Septal input. Neuroscience. vol 53. issue 4. 1993-07-08. PMID:8506030. |
these effects of cholinergic drugs were reproduced in animals without medial forebrain bundle. |
1993-07-08 |
2023-08-12 |
rabbit |
| O S Vinogradova, E S Brazhnik, V S Stafekhina, V F Kitchigin. Acetylcholine, theta-rhythm and activity of hippocampal neurons in the rabbit--III. Cortical input. Neuroscience. vol 53. issue 4. 1993-07-08. PMID:8506031. |
cholinergic modulation of single cell responses and field potentials evoked in the hippocampus by electrical stimulation of the perforant path and mossy fibres was investigated in two groups of chronic unanesthetized rabbits--with intact hippocampus and with basally undercut septum (without ascending medial forebrain bundle afferents). |
1993-07-08 |
2023-08-12 |
rabbit |
| E A Werber, J Chapman, A Arlazorof. Brainstem auditory evoked potentials in experimental autoimmune dementia. Neuroscience letters. vol 151. issue 2. 1993-07-08. PMID:8506086. |
cognitive dysfunction may be induced in rats by immunization with cholinergic neuronal antigens and is associated with degeneration of nuclei in the septum and hippocampus and white matter tracts in the forebrain. |
1993-07-08 |
2023-08-12 |
rat |
| D Maysinger, P Piccardo, M Goiny, A C Cuell. Grafting of genetically modified cells: effects of acetylcholine release in vivo. Neurochemistry international. vol 21. issue 4. 1993-06-29. PMID:1303736. |
in this study, microdialysis was used to investigate functional recovery of central cholinergic neurons in the forebrain of rats with cortical devascularizing lesions. |
1993-06-29 |
2023-08-11 |
rat |
| M R Palmer, M Eriksdotter-Nilsson, A Henschen, T Ebendal, L Olso. Nerve growth factor-induced excitation of selected neurons in the brain which is blocked by a low-affinity receptor antibody. Experimental brain research. vol 93. issue 2. 1993-06-16. PMID:8491263. |
our data suggest that forebrain cholinergic neurons may be selectively sensitive to ngf also at the neurophysiological level, responding by excitations, and that ngf upregulates these responses within less than an hour. |
1993-06-16 |
2023-08-12 |
Not clear |