| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J H Kordower, E Y Chen, J R Sladek, E J Mufso. trk-immunoreactivity in the monkey central nervous system: forebrain. The Journal of comparative neurology. vol 349. issue 1. 1995-03-16. PMID:7852624. |
these data indicate that both cholinergic and, possibly, noncholinergic forebrain neurons express the protein for the high-affinity trk receptor, which transduces the signal mediating the trophic effects of neurotrophins. |
1995-03-16 |
2023-08-12 |
monkey |
| F J Seidler, E S Albright, S E Lappi, T A Slotki. In search of a mechanism for receptor-mediated neurobehavioral teratogenesis by nicotine: catecholamine release by nicotine in immature rat brain regions. Brain research. Developmental brain research. vol 82. issue 1-2. 1995-03-09. PMID:7842497. |
nicotine did not stimulate catecholamine release at birth, but developed the capacity to do so in parallel with the ontogeny of nicotinic cholinergic receptors in the midbrain+brainstem and in the forebrain. |
1995-03-09 |
2023-08-12 |
human |
| C G van Eden, A Rinken. Lesion induced expression of low-affinity NGF-binding protein (p75) immunoreactivity after neonatal and adult aspiration lesions of the rat dorsomedial prefrontal cortex. Brain research. Developmental brain research. vol 82. issue 1-2. 1995-03-09. PMID:7842504. |
between 3 and 5 days after the operation, the greatest abundance of these fibers was found in the ventrorostral areas of the forebrain and along the pathways of cortical projections of the cholinergic cell groups. |
1995-03-09 |
2023-08-12 |
rat |
| J C Day, C S Tham, H C Fibige. Dopamine depletion attenuates amphetamine-induced increases of cortical acetylcholine release. European journal of pharmacology. vol 263. issue 3. 1995-03-03. PMID:7843266. |
these results point to an important role for forebrain dopamine in the regulation of cortically projecting cholinergic neurons and fail to support the hypothesis that the ascending noradrenergic projections of the locus coeruleus are significantly involved. |
1995-03-03 |
2023-08-12 |
rat |
| J R Leonard, D O Maris, M S Grad. Fluid percussion injury causes loss of forebrain choline acetyltransferase and nerve growth factor receptor immunoreactive cells in the rat. Journal of neurotrauma. vol 11. issue 4. 1995-02-27. PMID:7837279. |
cholinergic forebrain neurons are recognized for their role in memory. |
1995-02-27 |
2023-08-12 |
human |
| J R Leonard, D O Maris, M S Grad. Fluid percussion injury causes loss of forebrain choline acetyltransferase and nerve growth factor receptor immunoreactive cells in the rat. Journal of neurotrauma. vol 11. issue 4. 1995-02-27. PMID:7837279. |
we tested the hypothesis that forebrain cholinergic neurons are vulnerable to fluid percussion injury (fpi), a model of human tbi. |
1995-02-27 |
2023-08-12 |
human |
| L Ratnakumari, I A Qureshi, R F Butterwort. Evidence for cholinergic neuronal loss in brain in congenital ornithine transcarbamylase deficiency. Neuroscience letters. vol 178. issue 1. 1995-02-06. PMID:7816342. |
these results suggest that a loss of forebrain cholinergic neurons is a feature of congenital otc deficiency in these mutants. |
1995-02-06 |
2023-08-12 |
mouse |
| S M Brudzynsk. Ultrasonic vocalization induced by intracerebral carbachol in rats: localization and a dose-response study. Behavioural brain research. vol 63. issue 2. 1995-01-25. PMID:7999296. |
the results suggest that the cholinergic input into the mediobasal forebrain may play a physiological role in initiating and emitting the 22 khz ultrasonic vocalization in rats, and that changes in call duration, intensity and bandwidth may be involved in conveying information for conspecifics. |
1995-01-25 |
2023-08-12 |
rat |
| Y Koyama, T Toga, Y Kayama, A Sat. Regulation of regional blood flow in the laterodorsal thalamus by ascending cholinergic nerve fibers from the laterodorsal tegmental nucleus. Neuroscience research. vol 20. issue 1. 1995-01-05. PMID:7984342. |
the laterodorsal tegmental nucleus (ldt) is the largest aggregation in the brainstem of cholinergic neurons whose axons reach the thalamus as part of a diffuse projection to the forebrain. |
1995-01-05 |
2023-08-12 |
rat |
| W Fische. Nerve growth factor reverses spatial memory impairments in aged rats. Neurochemistry international. vol 25. issue 1. 1994-12-20. PMID:7950969. |
aged rats, displaying impairments in spatial learning and memory associated with marked cellular atrophy of forebrain cholinergic neurons, received intracerebroventricular infusions of the neurotrophin nerve growth factor (ngf), or vehicle. |
1994-12-20 |
2023-08-12 |
rat |
| S Rossner, J R Perez-Polo, R G Wiley, R Schliebs, V Big. Differential expression of immediate early genes in distinct layers of rat cerebral cortex after selective immunolesion of the forebrain cholinergic system. Journal of neuroscience research. vol 38. issue 3. 1994-11-16. PMID:7932863. |
differential expression of immediate early genes in distinct layers of rat cerebral cortex after selective immunolesion of the forebrain cholinergic system. |
1994-11-16 |
2023-08-12 |
rat |
| W Fischer, A Sirevaag, S J Wiegand, R M Lindsay, A Björklun. Reversal of spatial memory impairments in aged rats by nerve growth factor and neurotrophins 3 and 4/5 but not by brain-derived neurotrophic factor. Proceedings of the National Academy of Sciences of the United States of America. vol 91. issue 18. 1994-10-04. PMID:8078930. |
aged rats, displaying impairments in spatial learning and memory associated with marked cellular atrophy of forebrain cholinergic neurons, received intracerebroventricular infusions of one of the four neurotrophins nerve growth factor (ngf), brain-derived neurotrophic factor (bdnf), neurotrophin 3 (nt-3), or neurotrophin 4/5 (nt-4/5), or a combination of ngf and bdnf, or vehicle. |
1994-10-04 |
2023-08-12 |
rat |
| J L Venero, B Knüsel, K D Beck, F Heft. Expression of neurotrophin and trk receptor genes in adult rats with fimbria transections: effect of intraventricular nerve growth factor and brain-derived neurotrophic factor administration. Neuroscience. vol 59. issue 4. 1994-09-12. PMID:8058122. |
in the forebrain, specific hybridization labeling for trka messenger rna showed an identical pattern to that of choline acetyltransferase messenger rna, supporting the view that trka expression is confined to the cholinergic population in the basal forebrain and the cholinergic interneurons in the striatum. |
1994-09-12 |
2023-08-12 |
rat |
| C Scali, F Casamenti, M Pazzagli, L Bartolini, G Pepe. Nerve growth factor increases extracellular acetylcholine levels in the parietal cortex and hippocampus of aged rats and restores object recognition. Neuroscience letters. vol 170. issue 1. 1994-08-25. PMID:8041485. |
these findings indicate that both ach levels and memory impairment are improved in aged rats by ngf treatment and suggest that there is a relationship between object recognition and the activity of the forebrain cholinergic system. |
1994-08-25 |
2023-08-12 |
rat |
| A M Pallera, J B Schweitzer, A A Book, R G Wile. 192 IgG-saporin causes a major loss of synaptic content in rat olfactory bulb. Experimental neurology. vol 127. issue 2. 1994-08-17. PMID:8033966. |
an immunotoxin composed of a monoclonal antibody that recognizes the p75 nerve growth factor (ngf) receptor disulfide-linked to the ribosome-inactivating protein saporin selectively eliminates p75-expressing cholinergic neurons in the basal forebrain, while sparing other neurons in the forebrain, both cholinergic and noncholinergic. |
1994-08-17 |
2023-08-12 |
rat |
| G Richter-Levin, V Greenberger, M Sega. The effects of general and restricted serotonergic lesions on hippocampal electrophysiology and behavior. Brain research. vol 642. issue 1-2. 1994-08-16. PMID:8032871. |
depletion of the forebrain serotonergic system was found in previous studies to induce an increased excitability of the dentate gyrus (dg) granule cells and, when combined with a cholinergic deficiency, to impair spatial learning. |
1994-08-16 |
2023-08-12 |
rat |
| C A Kitt, C Höhmann, J T Coyle, D L Pric. Cholinergic innervation of mouse forebrain structures. The Journal of comparative neurology. vol 341. issue 1. 1994-07-15. PMID:8006218. |
cholinergic innervation of mouse forebrain structures. |
1994-07-15 |
2023-08-12 |
mouse |
| C A Kitt, C Höhmann, J T Coyle, D L Pric. Cholinergic innervation of mouse forebrain structures. The Journal of comparative neurology. vol 341. issue 1. 1994-07-15. PMID:8006218. |
the results of this study provide the basis for examining the effects of transgenes and age on forebrain cholinergic systems. |
1994-07-15 |
2023-08-12 |
mouse |
| J M Lee, E R Ross, A Gower, J M Paris, R Martensson, S A Loren. Spatial learning deficits in the aged rat: neuroanatomical and neurochemical correlates. Brain research bulletin. vol 33. issue 5. 1994-06-21. PMID:8186994. |
therefore, either the cholinergic cell loss in the septum is unrelated to the acquisition of spatial learning measured by the morris water maze, or it is a permissive effect along with specific alterations in forebrain dopaminergic and serotonergic systems, particularly in the medial frontal cortex and n. accumbens. |
1994-06-21 |
2023-08-12 |
rat |
| A R Bentivoglio, M C Altavista, R Granata, A Albanes. Genetically determined cholinergic deficiency in the forebrain of C57BL/6 mice. Brain research. vol 637. issue 1-2. 1994-06-16. PMID:8180796. |
genetically determined cholinergic deficiency in the forebrain of c57bl/6 mice. |
1994-06-16 |
2023-08-12 |
mouse |