| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A R Bentivoglio, M C Altavista, R Granata, A Albanes. Genetically determined cholinergic deficiency in the forebrain of C57BL/6 mice. Brain research. vol 637. issue 1-2. 1994-06-16. PMID:8180796. |
this study demonstrates that a deficiency of forebrain cholinergic neurons occurs in c57bl/6 (c57) mice, a strain characterized by poor learning capabilities. |
1994-06-16 |
2023-08-12 |
mouse |
| A R Bentivoglio, M C Altavista, R Granata, A Albanes. Genetically determined cholinergic deficiency in the forebrain of C57BL/6 mice. Brain research. vol 637. issue 1-2. 1994-06-16. PMID:8180796. |
as compared to the dba strain, c57 mice had a reduced number of forebrain cholinergic neurons. |
1994-06-16 |
2023-08-12 |
mouse |
| A R Bentivoglio, M C Altavista, R Granata, A Albanes. Genetically determined cholinergic deficiency in the forebrain of C57BL/6 mice. Brain research. vol 637. issue 1-2. 1994-06-16. PMID:8180796. |
these data show that c57 mice can be regarded as a genetic mutant, whose phenotype is characterized by a reduced number of forebrain cholinergic neurons and by cognitive abnormalities. |
1994-06-16 |
2023-08-12 |
mouse |
| C Eva, M Fusco, R Brusa, N Schiavo, S Ricci Gamalero, G Vantini, E Genazzan. Intracerebroventricular administration of nerve growth factor affects muscarinic cholinergic receptors in the cerebral cortex of neonatal rats. Neurochemistry international. vol 24. issue 1. 1994-04-21. PMID:8130736. |
the repeated intracerebroventricular administration of nerve growth factor (5 micrograms/2.5 microliters) to neonatal rats induced the activation of choline acetyltransferase in forebrain cholinergic neurons that was paralleled by a concomitant change in the density of muscarinic cholinergic receptors in the cerebral cortex. |
1994-04-21 |
2023-08-12 |
rat |
| R De Simone, L Alo. Influence of ethanol consumption on brain nerve growth factor and its target cells in developing and adult rodents. Annali dell'Istituto superiore di sanita. vol 29. issue 1. 1994-04-11. PMID:8129266. |
the results indicate that the damaging effect of alcohol on forebrain cholinergic neurons is also associated with impairment of central ngf-target structures. |
1994-04-11 |
2023-08-12 |
rat |
| W Wallace, V Haroutunia. Using the subcortically lesioned rat cortex to understand the physiological role of amyloid precursor protein. Behavioural brain research. vol 57. issue 2. 1994-04-06. PMID:8117425. |
these models have been useful for the investigation of some discrete aspects of alzheimer's disease, including deficits in forebrain cholinergic activity and the resulting cognitive deficits. |
1994-04-06 |
2023-08-12 |
mouse |
| A C Granholm, C Bäckman, F Bloom, T Ebendal, G A Gerhardt, B Hoffer, L Mackerlova, L Olson, S Söderström, L R Walu. NGF and anti-transferrin receptor antibody conjugate: short and long-term effects on survival of cholinergic neurons in intraocular septal transplants. The Journal of pharmacology and experimental therapeutics. vol 268. issue 1. 1994-03-10. PMID:8301587. |
we describe a new molecular carrier system that allows for the transport of nerve growth factor (ngf) across the blood-brain barrier (bbb), as assessed by trophic effects on intraocular forebrain transplants that contain central cholinergic neurons. |
1994-03-10 |
2023-08-12 |
rat |
| I Gritti, L Mainville, B E Jone. Projections of GABAergic and cholinergic basal forebrain and GABAergic preoptic-anterior hypothalamic neurons to the posterior lateral hypothalamus of the rat. The Journal of comparative neurology. vol 339. issue 2. 1994-03-04. PMID:8300907. |
in the present study, descending projections of the gabaergic and cholinergic neurons were investigated to the lateral posterior hypothalamus (lhp) through which the medial forebrain bundle passes and where another major forebrain source of subcortical afferents is situated. |
1994-03-04 |
2023-08-12 |
rat |
| V V Raevskii, C Tegetmayer, A A Trifono. Does the destruction of catecholaminergic neurons in newborn rats influence the modulator function of the cholinergic system? Neuroscience and behavioral physiology. vol 23. issue 6. 1994-02-24. PMID:8290031. |
it was demonstrated that destruction of the ca system in newborn rats increases the reactivity of neurons somatosensory cortex to sensory stimulation, has no influence on the modulating effect of the cholinergic system, of the forebrain, and leads to intensification of the modulating influence of applied ach [2]. |
1994-02-24 |
2023-08-12 |
rat |
| G Tsai, B S Slusher, L Sim, J T Coyl. Immunocytochemical distribution of N-acetylaspartylglutamate in the rat forebrain and glutamatergic pathways. Journal of chemical neuroanatomy. vol 6. issue 5. 1994-02-10. PMID:7903856. |
co-localization of naag-li to cholinergic systems of the forebrain was quite extensive with the exception of the striatal local circuit neurons. |
1994-02-10 |
2023-08-12 |
rat |
| Y Ichitani, M Tanaka, H Okamura, Y Ibat. Cholinergic neurons contain Calbindin-D28k in the monkey medial septal nucleus and nucleus of the diagonal band: an immunocytochemical study. Brain research. vol 625. issue 2. 1994-02-08. PMID:8275315. |
the distribution patterns of choline acetyltransferase (cat), as a marker for cholinergic neurons, and calbindin-d28k (cabp) immunoreactivities in the forebrain basal ganglia of the japanese monkey macaca fuscata were compared. |
1994-02-08 |
2023-08-12 |
cat |
| J K Robinson, J N Crawle. Intraseptal galanin potentiates scopolamine impairment of delayed nonmatching to sample. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 12. 1994-01-12. PMID:7504722. |
these findings raise the possibility that endogenous galanin may exacerbate cognitive impairments associated with forebrain cholinergic deficits. |
1994-01-12 |
2023-08-12 |
rat |
| S Aspley, K C Fon. Galanin fails to alter both acquisition of a two trial per day water maze task and neurochemical markers of cholinergic or serotonergic neurones in adult rats. Brain research. vol 622. issue 1-2. 1994-01-06. PMID:7694768. |
the co-existence of galanin with acetylcholine in ventral forebrain neurones combined with evidence that galanin attenuates cholinergic function and is present in senile plaques in alzheimer's disease all implicate this neuropeptide in the regulation of cognition. |
1994-01-06 |
2023-08-12 |
rat |
| S Aspley, K C Fon. Galanin fails to alter both acquisition of a two trial per day water maze task and neurochemical markers of cholinergic or serotonergic neurones in adult rats. Brain research. vol 622. issue 1-2. 1994-01-06. PMID:7694768. |
this study simultaneously examines the effect of galanin on acquisition in a morris water maze and post-training markers of cholinergic and serotonergic forebrain neurones thought to be involved in cognition. |
1994-01-06 |
2023-08-12 |
rat |
| A C Cuell. Trophic responses of forebrain cholinergic neurons: a discussion. Progress in brain research. vol 98. 1994-01-06. PMID:8248516. |
trophic responses of forebrain cholinergic neurons: a discussion. |
1994-01-06 |
2023-08-12 |
Not clear |
| S B Dunnett, H C Fibige. Role of forebrain cholinergic systems in learning and memory: relevance to the cognitive deficits of aging and Alzheimer's dementia. Progress in brain research. vol 98. 1994-01-06. PMID:8248529. |
role of forebrain cholinergic systems in learning and memory: relevance to the cognitive deficits of aging and alzheimer's dementia. |
1994-01-06 |
2023-08-12 |
Not clear |
| D M Armstrong, R Sheffield, G Buzsaki, K S Chen, L B Hersh, B Nearing, F H Gag. Morphologic alterations of choline acetyltransferase-positive neurons in the basal forebrain of aged behaviorally characterized Fisher 344 rats. Neurobiology of aging. vol 14. issue 5. 1994-01-04. PMID:8247228. |
prior to sacrifice and morphometric analyses of forebrain cholinergic neurons all rats underwent behavioral characterization in a spatial learning task using the morris water maze. |
1994-01-04 |
2023-08-12 |
rat |
| D M Armstrong, R Sheffield, G Buzsaki, K S Chen, L B Hersh, B Nearing, F H Gag. Morphologic alterations of choline acetyltransferase-positive neurons in the basal forebrain of aged behaviorally characterized Fisher 344 rats. Neurobiology of aging. vol 14. issue 5. 1994-01-04. PMID:8247228. |
quantitative assessment of the size and density of choline acetyltransferase (chat)-positive neurons throughout the basal forebrain revealed a significant enlargement of forebrain cholinergic neurons within 27-month-old nonimpaired rats compared to 6-month-old rats and 27- and 33-month-old impaired animals. |
1994-01-04 |
2023-08-12 |
rat |
| D M Armstrong, R Sheffield, G Buzsaki, K S Chen, L B Hersh, B Nearing, F H Gag. Morphologic alterations of choline acetyltransferase-positive neurons in the basal forebrain of aged behaviorally characterized Fisher 344 rats. Neurobiology of aging. vol 14. issue 5. 1994-01-04. PMID:8247228. |
although the significance of enlarged forebrain cholinergic neurons is unclear, we discuss the possibility that within aged rodents neuronal swelling is an active event and represents an early manifestation of the aging process and may constitute a restorative and/or compensatory event in that these rats are relatively asymptomatic with respect to their behavioral deficits. |
1994-01-04 |
2023-08-12 |
rat |
| D M Michaelson, V Dubovik, M Faigon, D Eilam, J Feldo. Decreased density of forebrain cholinergic neurons and disintegration of the spatial organization of behavior in experimental autoimmune dementia (EAD). Annals of the New York Academy of Sciences. vol 695. 1993-12-10. PMID:8239291. |
decreased density of forebrain cholinergic neurons and disintegration of the spatial organization of behavior in experimental autoimmune dementia (ead). |
1993-12-10 |
2023-08-12 |
rat |