| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| E Gould, N J Woolf, L L Butche. Postnatal development of cholinergic neurons in the rat: I. Forebrain. Brain research bulletin. vol 27. issue 6. 1992-03-24. PMID:1664779. |
postnatal development of cholinergic neurons in the rat: i. forebrain. |
1992-03-24 |
2023-08-11 |
rat |
| E Gould, N J Woolf, L L Butche. Postnatal development of cholinergic neurons in the rat: I. Forebrain. Brain research bulletin. vol 27. issue 6. 1992-03-24. PMID:1664779. |
the postnatal development of cholinergic projection and local-circuit neurons in the rat forebrain was examined by use of choline acetyltransferase (chat) immunohistochemistry and acetylcholinesterase (ache) histochemistry. |
1992-03-24 |
2023-08-11 |
rat |
| E Gould, N J Woolf, L L Butche. Postnatal development of cholinergic neurons in the rat: I. Forebrain. Brain research bulletin. vol 27. issue 6. 1992-03-24. PMID:1664779. |
cholinergic neurons in all forebrain regions also underwent an initial stage of progressive soma and proximal-dendrite hypertrophy, which peaked during the third postnatal week, followed by a period of cell-body and dendritic shrinkage that persisted into the fifth postnatal week when adult configurations were reached. |
1992-03-24 |
2023-08-11 |
rat |
| H Hodges, Y Allen, T Kershaw, P L Lantos, J A Gray, J Sinde. Effects of cholinergic-rich neural grafts on radial maze performance of rats after excitotoxic lesions of the forebrain cholinergic projection system--I. Amelioration of cognitive deficits by transplants into cortex and hippocampus but not into basal forebrain. Neuroscience. vol 45. issue 3. 1992-03-04. PMID:1775235. |
effects of cholinergic-rich neural grafts on radial maze performance of rats after excitotoxic lesions of the forebrain cholinergic projection system--i. amelioration of cognitive deficits by transplants into cortex and hippocampus but not into basal forebrain. |
1992-03-04 |
2023-08-11 |
rat |
| H Hodges, Y Allen, T Kershaw, P L Lantos, J A Gray, J Sinde. Effects of cholinergic-rich neural grafts on radial maze performance of rats after excitotoxic lesions of the forebrain cholinergic projection system--I. Amelioration of cognitive deficits by transplants into cortex and hippocampus but not into basal forebrain. Neuroscience. vol 45. issue 3. 1992-03-04. PMID:1775235. |
after ibotenate (10.0 mg/ml) lesions to the nucleus basalis and medial septal regions, at the source of the cortical and hippocampal branches of the forebrain cholinergic projection system, rats displayed long-lasting stable impairment in reference and working memory in both spatial (place) and associative (cue) radial maze tasks. |
1992-03-04 |
2023-08-11 |
rat |
| H Hodges, Y Allen, T Kershaw, P L Lantos, J A Gray, J Sinde. Effects of cholinergic-rich neural grafts on radial maze performance of rats after excitotoxic lesions of the forebrain cholinergic projection system--I. Amelioration of cognitive deficits by transplants into cortex and hippocampus but not into basal forebrain. Neuroscience. vol 45. issue 3. 1992-03-04. PMID:1775235. |
the equipotency of grafts within each terminal region suggests also that there may be a considerable degree of functional cooperation between the two branches of the forebrain cholinergic projection system. |
1992-03-04 |
2023-08-11 |
rat |
| H Hodges, Y Allen, J Sinden, P L Lantos, J A Gra. Effects of cholinergic-rich neural grafts on radial maze performance of rats after excitotoxic lesions of the forebrain cholinergic projection system--II. Cholinergic drugs as probes to investigate lesion-induced deficits and transplant-induced functional recovery. Neuroscience. vol 45. issue 3. 1992-03-04. PMID:1775236. |
effects of cholinergic-rich neural grafts on radial maze performance of rats after excitotoxic lesions of the forebrain cholinergic projection system--ii. |
1992-03-04 |
2023-08-11 |
rat |
| H Sakaguchi, N Sait. Developmental change of cholinergic activity in the forebrain of the zebra finch during song learning. Brain research. Developmental brain research. vol 62. issue 2. 1992-02-26. PMID:1769101. |
developmental change of cholinergic activity in the forebrain of the zebra finch during song learning. |
1992-02-26 |
2023-08-11 |
Not clear |
| S R McGurk, E D Levin, L L Butche. Impairment of radial-arm maze performance in rats following lesions involving the cholinergic medial pathway: reversal by arecoline and differential effects of muscarinic and nicotinic antagonists. Neuroscience. vol 44. issue 1. 1992-02-21. PMID:1770993. |
although numerous studies have suggested that pathways deriving from the basal nuclear complex of the forebrain are critical for the cholinergic modulation of learning and memory, most have focussed on the septohippocampal projection, and none have specifically targeted the medial or lateral systems. |
1992-02-21 |
2023-08-11 |
rat |
| S Dunnet. Cholinergic grafts, memory and ageing. Trends in neurosciences. vol 14. issue 8. 1992-01-28. PMID:1721745. |
the transplantation technique enhances our understanding of the involvement of forebrain cholinergic systems in normal cognitive functions (including memory) and of the role of cholinergic degeneration in the dysfunctions associated with ageing. |
1992-01-28 |
2023-08-11 |
human |
| S Dunnet. Cholinergic grafts, memory and ageing. Trends in neurosciences. vol 14. issue 8. 1992-01-28. PMID:1721745. |
it is unlikely, however, that these observations will extend to a therapeutic strategy for dementia using neural transplantation, because the human diseases (at least in the case of alzheimer's disease and multi-infarct dementia) involve widespread degeneration of other populations of cortical neurones that are not so amenable to functional transplantation as the diffuse forebrain cholinergic systems. |
1992-01-28 |
2023-08-11 |
human |
| C R Gerfe. Substance P (neurokinin-1) receptor mRNA is selectively expressed in cholinergic neurons in the striatum and basal forebrain. Brain research. vol 556. issue 1. 1991-12-03. PMID:1718557. |
thus, in the rat forebrain the substance p receptor appears to be expressed selectively by cholinergic neurons. |
1991-12-03 |
2023-08-11 |
rat |
| J D Oh, L L Butcher, N J Wool. Thyroid hormone modulates the development of cholinergic terminal fields in the rat forebrain: relation to nerve growth factor receptor. Brain research. Developmental brain research. vol 59. issue 2. 1991-11-18. PMID:1655305. |
thyroid hormone modulates the development of cholinergic terminal fields in the rat forebrain: relation to nerve growth factor receptor. |
1991-11-18 |
2023-08-11 |
rat |
| J D Oh, L L Butcher, N J Wool. Thyroid hormone modulates the development of cholinergic terminal fields in the rat forebrain: relation to nerve growth factor receptor. Brain research. Developmental brain research. vol 59. issue 2. 1991-11-18. PMID:1655305. |
these cells also do not demonstrate ngf-r. we conclude from these experiments (1) that cholinergic fiber plexuses eventually exhibiting chat positivity in the telencephalon demonstrate ngf-r prior to the cholinergic synthetic enzyme, (2) that susceptibility to thyroid hormone manipulations may involve sensitivity to ngf, at least in some forebrain cholinergic systems and (3) that the effects of thyroid hormone imbalances on brain cholinergic neurons are regionally selective. |
1991-11-18 |
2023-08-11 |
rat |
| A C Cuello, L Garofalo, D Maysinge. Evidence for nerve growth factor-ganglioside interaction in forebrain cholinergic neurons. Acta neurobiologiae experimentalis. vol 50. issue 4-5. 1991-11-13. PMID:2130661. |
evidence for nerve growth factor-ganglioside interaction in forebrain cholinergic neurons. |
1991-11-13 |
2023-08-11 |
Not clear |
| A C Cuello, L Garofalo, D Maysinge. Evidence for nerve growth factor-ganglioside interaction in forebrain cholinergic neurons. Acta neurobiologiae experimentalis. vol 50. issue 4-5. 1991-11-13. PMID:2130661. |
cholinergic neurons of the forebrain respond trophically to nerve growth factor (ngf) in some experimental circumstances. |
1991-11-13 |
2023-08-11 |
Not clear |
| J A Sim, W H Griffit. Muscarinic agonists block a late-afterhyperpolarization in medial septum/diagonal band neurons in vitro. Neuroscience letters. vol 129. issue 1. 1991-11-05. PMID:1681481. |
these forebrain nuclei contain both cholinergic and noncholinergic neurons that project to the cortex and hippocampus and are involved in many cortical functions. |
1991-11-05 |
2023-08-11 |
Not clear |
| H Yunshao, Y Zhibin, C Yic. Effect of nerve growth factor on the lesioned septohippocampal cholinergic system of aged rats. Brain research. vol 552. issue 1. 1991-11-04. PMID:1655166. |
moreover, these findings suggest that the responses of basal forebrain cholinergic neurons to ngf treatment varies with time after the lesion and imply that the ngf administration can promote the collateral sprouting from spared cholinergic fibers after the lesion in the aged forebrain. |
1991-11-04 |
2023-08-11 |
rat |
| S Ikegami, I Nihonmatsu, H Kawamur. Transplantation of ventral forebrain cholinergic neurons to the hippocampus ameliorates impairment of radial-arm maze learning in rats with AF64A treatment. Brain research. vol 548. issue 1-2. 1991-09-19. PMID:1868334. |
transplantation of ventral forebrain cholinergic neurons to the hippocampus ameliorates impairment of radial-arm maze learning in rats with af64a treatment. |
1991-09-19 |
2023-08-11 |
rat |
| J C Lauterborn, P J Isackson, C M Gal. Nerve growth factor mRNA-containing cells are distributed within regions of cholinergic neurons in the rat basal forebrain. The Journal of comparative neurology. vol 306. issue 3. 1991-09-11. PMID:1865003. |
it has been proposed that nerve growth factor (ngf) provides critical trophic support for the cholinergic neurons of the basal forebrain and that it becomes available to these neurons by retrograde transport from distant forebrain targets. |
1991-09-11 |
2023-08-11 |
rat |