| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Anthony D Miller, Charles D Blah. Midbrain muscarinic receptor mechanisms underlying regulation of mesoaccumbens and nigrostriatal dopaminergic transmission in the rat. The European journal of neuroscience. vol 21. issue 7. 2005-07-05. PMID:15869479. |
laterodorsal (ldt) and pedunculopontine (ppt) tegmental nuclei in the mesopontine project cholinergic inputs to the midbrain ventral tegmental area (vta) and substantia nigra pars compacta (snc), respectively, to directly and indirectly influence the activity of dopamine neuronal cells via actions on muscarinic and nicotinic receptors. |
2005-07-05 |
2023-08-12 |
rat |
| Eleni T Tzavara, Frank P Bymaster, Richard J Davis, Mark R Wade, Kenneth W Perry, Jurgen Wess, David L McKinzie, Chris Felder, George G Nomiko. M4 muscarinic receptors regulate the dynamics of cholinergic and dopaminergic neurotransmission: relevance to the pathophysiology and treatment of related CNS pathologies. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 18. issue 12. 2005-04-05. PMID:15231726. |
we also demonstrated impaired homeostatic control of cholinergic activity that leads to increased basal acetylcholine efflux in the midbrain of these animals. |
2005-04-05 |
2023-08-12 |
mouse |
| Miguel Díaz-Hernández, Jesús Sánchez-Nogueiro, Jesús Pintor, M Teresa Miras-Portuga. Interaction between dinucleotide and nicotinic receptors in individual cholinergic terminals. The Journal of pharmacology and experimental therapeutics. vol 311. issue 3. 2005-01-13. PMID:15254146. |
functional ionotropic nucleotidic receptors responding to diadenosine pentaphospate and nicotinic receptors responding to epibatidine coexpress in 19% of the total rat midbrain cholinergic terminals, as determined by the combination of immunological and microfluorimetric techniques. |
2005-01-13 |
2023-08-12 |
rat |
| François J Michel, Julie M Robillard, Louis-Eric Trudea. Regulation of rat mesencephalic GABAergic neurones through muscarinic receptors. The Journal of physiology. vol 556. issue Pt 2. 2004-11-09. PMID:14766941. |
cholinergic neurones, originating from mesopontine nuclei, project profusely in the mesencephalon where they preferentially synapse onto local gabaergic neurones. |
2004-11-09 |
2023-08-12 |
rat |
| Jonathan Dennis Carlson, Robert Paul Iacono, George Maed. Nociceptive excited and inhibited neurons within the pedunculopontine tegmental nucleus and cuneiform nucleus. Brain research. vol 1013. issue 2. 2004-08-25. PMID:15193527. |
the pedunculopontine tegmental nucleus (pptg) is defined by its collection of cholinergic neurons surrounding the lateral portion of the superior cerebellar peduncle at the midbrain pontine junction. |
2004-08-25 |
2023-08-12 |
rat |
| Yael Abreu-Villaça, Frederic J Seidler, Dan Qiao, Charlotte A Tate, Mandy M Cousins, Indira Thillai, Theodore A Slotki. Short-term adolescent nicotine exposure has immediate and persistent effects on cholinergic systems: critical periods, patterns of exposure, dose thresholds. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 28. issue 11. 2004-01-28. PMID:12784097. |
in the cerebral cortex, midbrain, and hippocampus, we assessed nicotinic cholinergic receptor (nachr) binding, choline acetyltransferase (chat) activity, a constitutive marker for cholinergic nerve terminals, and [(3)h]hemicholinium-3 (hc-3) binding to the high-affinity choline transporter, which responds to cholinergic synaptic stimulation. |
2004-01-28 |
2023-08-12 |
rat |
| Tetsuji Yamashita, Tadashi Is. Ca2+-dependent inward current induced by nicotinic receptor activation depends on Ca2+/calmodulin-CaMKII pathway in dopamine neurons. Neuroscience research. vol 47. issue 2. 2003-12-11. PMID:14512147. |
it is well known that midbrain dopamine (da) neurons receive massive projection from cholinergic neurons in the brainstem. |
2003-12-11 |
2023-08-12 |
Not clear |
| Satomi Kasashima, Yoshio Od. Cholinergic neuronal loss in the basal forebrain and mesopontine tegmentum of progressive supranuclear palsy and corticobasal degeneration. Acta neuropathologica. vol 105. issue 2. 2003-04-23. PMID:12536222. |
to characterize the vulnerability of the forebrain and midbrain cholinergic systems in psp and cbd, we performed a comparative study of cholinergic neuronal changes in the nucleus basalis of meynert (nbm) and the laterodorsal tegmental and pedunculopontine tegmental nuclei (ldtgn and pptgn) of brains obtained at autopsy (three cases of psp, one case of cbd and six cases without neurological diseases) by immunohistochemistry for choline acetyltransferase (chat) and gallyas-braak staining. |
2003-04-23 |
2023-08-12 |
Not clear |
| Fu-Ming Zhou, Charles Wilson, John A Dan. Muscarinic and nicotinic cholinergic mechanisms in the mesostriatal dopamine systems. The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 9. issue 1. 2003-04-16. PMID:12580337. |
the midbrain da areas receive cholinergic innervation from the pedunculopontine tegmentum and the laterodorsal pontine tegmentum, whereas the striatum receives dense cholinergic innervation from local interneurons. |
2003-04-16 |
2023-08-12 |
Not clear |
| G L Forster, A J Falcon, A D Miller, G A Heruc, C D Blah. Effects of laterodorsal tegmentum excitotoxic lesions on behavioral and dopamine responses evoked by morphine and d-amphetamine. Neuroscience. vol 114. issue 4. 2003-01-10. PMID:12379238. |
cholinergic and glutamatergic projections from the laterodorsal tegmental nucleus (ldt) in the rat pons excite midbrain dopamine cells to directly modulate forebrain dopamine transmission. |
2003-01-10 |
2023-08-12 |
rat |
| A Tales, T Troscianko, D Lush, J Haworth, G K Wilcock, S R Butle. The pupillary light reflex in aging and Alzheimer's disease. Aging (Milan, Italy). vol 13. issue 6. 2002-08-13. PMID:11845975. |
the impairment is likely to be caused by degeneration in relays in the midbrain but cholinergic deficits in the peripheral parasympathetic pathway cannot be excluded. |
2002-08-13 |
2023-08-12 |
Not clear |
| A D Miller, G L Forster, K M Metcalf, C D Blah. Excitotoxic lesions of the pedunculopontine differentially mediate morphine- and d-amphetamine-evoked striatal dopamine efflux and behaviors. Neuroscience. vol 111. issue 2. 2002-08-13. PMID:11983320. |
cholinergic and glutamatergic cells in the pedunculopontine tegmental nucleus are a principal source of excitatory input to midbrain dopamine neurons projecting to the striatum. |
2002-08-13 |
2023-08-12 |
rat |
| Takeshi Sakura. Roles of orexins in regulation of feeding and wakefulness. Neuroreport. vol 13. issue 8. 2002-07-26. PMID:12060794. |
these neurons project to numerous brain regions, with monoaminergic and cholinergic nuclei of the hypothalamus, midbrain, and pons receiving particularly strong innervations. |
2002-07-26 |
2023-08-12 |
Not clear |
| Pernilla Grillner, Nicola B Mercur. Intrinsic membrane properties and synaptic inputs regulating the firing activity of the dopamine neurons. Behavioural brain research. vol 130. issue 1-2. 2002-05-16. PMID:11864731. |
in the present paper we review electrophysiological data regarding the role of glutamatergic and cholinergic and gabaergic afferent inputs in regulating the midbrain daergic neuronal activity. |
2002-05-16 |
2023-08-12 |
Not clear |
| Miguel Díaz-Hernández, Jesús Pintor, Enrique Castro, M Teresa Miras-Portuga. Co-localisation of functional nicotinic and ionotropic nucleotide receptors in isolated cholinergic synaptic terminals. Neuropharmacology. vol 42. issue 1. 2002-02-20. PMID:11750913. |
the combination of immunological and microfluorimetric techniques has permitted the identification and analysis of the ca2+ influx responses in single rat midbrain cholinergic terminals. |
2002-02-20 |
2023-08-12 |
rat |
| W A Corrigall, K M Coen, J Zhang, K L Adamso. GABA mechanisms in the pedunculopontine tegmental nucleus influence particular aspects of nicotine self-administration selectively in the rat. Psychopharmacology. vol 158. issue 2. 2002-02-13. PMID:11702093. |
the cholinergic neurons of the pptg comprise a prominent projection to midbrain dopamine neurons. |
2002-02-13 |
2023-08-12 |
rat |
| Gina L Forster, John S Yeomans, Junichi Takeuchi, Charles D Blah. M5 muscarinic receptors are required for prolonged accumbal dopamine release after electrical stimulation of the pons in mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 1. 2002-02-04. PMID:11756520. |
midbrain dopamine neurons are activated directly by cholinergic agonists or by stimulation of the cholinergic neurons in the laterodorsal tegmental nucleus (ldt) of the pons in rats. |
2002-02-04 |
2023-08-12 |
mouse |
| Y Yamao, Y Koyama, K Akihiro, K Yukihiko, M Tsunehar. Discrete regions in the laterodorsal tegmental area of the rat regulating the urinary bladder and external urethral sphincter. Brain research. vol 912. issue 2. 2001-12-07. PMID:11532432. |
stimulation of a small area around the ventrolateral edge of the central gray in a plane at the junction of the mesencephalon and pons, where cholinergic neurons in the laterodorsal tegmental nucleus formed the largest mass, induced contraction only of the bladder. |
2001-12-07 |
2023-08-12 |
rat |
| D Nakahara, Y Ishida, M Nakamura, N Furuno, T Nishimor. Intracranial self-stimulation induces Fos expression in GABAergic neurons in the rat mesopontine tegmentum. Neuroscience. vol 106. issue 3. 2001-12-07. PMID:11591463. |
the cholinergic neurons which originate in the mesopontine tegmentum and innervate the midbrain ventral tegmental area have been proposed to play a key role in intracranial self-stimulation reward. |
2001-12-07 |
2023-08-12 |
rat |
| T A Slotkin, M M Cousins, C A Tate, F J Seidle. Persistent cholinergic presynaptic deficits after neonatal chlorpyrifos exposure. Brain research. vol 902. issue 2. 2001-08-09. PMID:11384617. |
we then examined two cholinergic synaptic markers, choline acetyltransferase activity (chat) and [3h]hemicholinium-3 binding (hc-3) in the hippocampus, midbrain, striatum, brainstem and cerebral cortex in the juvenile (pn30) and young adult (pn60). |
2001-08-09 |
2023-08-12 |
rat |