| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A D Zurn, F Werre. Development of CNS cholinergic neurons in vitro: selective effects of CNTF and LIF on neurons from mesencephalic cranial motor nuclei. Developmental biology. vol 163. issue 2. 1994-07-05. PMID:7911111. |
we report here that cntf and lif increase choline acetyltransferase (chat) activity three- to fourfold in cultures from the ventral mesencephalon (vm) containing cholinergic neurons from cranial motor nuclei and the pedunculopontine nucleus, but decrease tyrosine hydroxylase activity to 50-60% of control values. |
1994-07-05 |
2023-08-12 |
Not clear |
| M Takashima, M Takita, A Umino, T Nishikawa, H Mitsushio, K Takahash. Modulation of cerebral acetylcholine metabolism by the dorsal diencephalic conduction system in the rat. Neurochemistry international. vol 20. issue 4. 1993-07-15. PMID:1304873. |
these findings suggest that the dorsal diencephalic conduction system may be involved in the integration of the activity of cholinergic neurons in the forebrain and midbrain regions and striatal dopanine neurons may play a role in the modulation of cholinergic neurons. |
1993-07-15 |
2023-08-11 |
rat |
| O G Nilsson, G Leanza, C Rosenblad, D A Lappi, R G Wiley, A Björklun. Spatial learning impairments in rats with selective immunolesion of the forebrain cholinergic system. Neuroreport. vol 3. issue 11. 1993-02-16. PMID:1482757. |
chat activity associated with other cholinergic neurone systems in the brain (striatum, mesencephalon, spinal cord), was left virtually unaffected. |
1993-02-16 |
2023-08-11 |
rat |
| E M Sorenson, V A Chiappinell. Localization of 3H-nicotine, 125I-kappa-bungarotoxin, and 125I-alpha-bungarotoxin binding to nicotinic sites in the chicken forebrain and midbrain. The Journal of comparative neurology. vol 323. issue 1. 1992-12-22. PMID:1430311. |
we have previously localized cholinergic cell bodies and fibers within the midbrain of the chicken with choline acetyltransferase immunohistochemistry. |
1992-12-22 |
2023-08-11 |
rat |
| E M Sorenson, V A Chiappinell. Localization of 3H-nicotine, 125I-kappa-bungarotoxin, and 125I-alpha-bungarotoxin binding to nicotinic sites in the chicken forebrain and midbrain. The Journal of comparative neurology. vol 323. issue 1. 1992-12-22. PMID:1430311. |
in a continuing effort to characterize the central cholinergic system, the present study examines the distribution of various nicotinic acetylcholine receptors in the forebrain and midbrain of the chicken. |
1992-12-22 |
2023-08-11 |
rat |
| J Grenhoff, T H Svensso. Nicotinic and muscarinic components of rat brain dopamine synthesis stimulation induced by physostigmine. Naunyn-Schmiedeberg's archives of pharmacology. vol 346. issue 4. 1992-12-01. PMID:1436125. |
the role of a putative cholinergic control of ascending midbrain dopamine neurons was studied with biochemical methods in the unanaesthetized male albino rat. |
1992-12-01 |
2023-08-11 |
rat |
| R Chen, S E Robinso. The effect of cobrotoxin on cholinergic neurons in the mouse. Life sciences. vol 51. issue 13. 1992-10-09. PMID:1522750. |
these results suggest that the activity of hippocampal and midbrain cholinergic neurons is suppressed by ct, whereas the activity of striatal and thalamic cholinergic neurons is increased by ct at a time when a maximum analgesic response to ct is expressed. |
1992-10-09 |
2023-08-11 |
mouse |
| T L Steininger, D B Rye, B H Waine. Afferent projections to the cholinergic pedunculopontine tegmental nucleus and adjacent midbrain extrapyramidal area in the albino rat. I. Retrograde tracing studies. The Journal of comparative neurology. vol 321. issue 4. 1992-09-18. PMID:1380518. |
afferent projections to the cholinergic pedunculopontine tegmental nucleus and adjacent midbrain extrapyramidal area in the albino rat. |
1992-09-18 |
2023-08-11 |
rat |
| E Garcia-Rill, D L Davies, R D Skinner, J A Biedermann, C McHalffe. Fibroblast growth factor-induced increased survival of cholinergic mesopontine neurons in culture. Brain research. Developmental brain research. vol 60. issue 2. 1991-10-21. PMID:1893568. |
basic fibroblast growth factor (bfgf) was found to increase the survival of immunocytochemically-identified cholinergic mesopontine neurons in dissociated cell cultures of embryonic rat midbrain. |
1991-10-21 |
2023-08-11 |
rat |
| J P Bolam, C M Francis, Z Henderso. Cholinergic input to dopaminergic neurons in the substantia nigra: a double immunocytochemical study. Neuroscience. vol 41. issue 2-3. 1991-09-13. PMID:1678502. |
sections of perfusion-fixed mesencephalon were incubated first to reveal choline acetyltransferase immunoreactivity to label the cholinergic terminals and then tyrosine hydroxylase immunoreactivity to label the dopaminergic neurons. |
1991-09-13 |
2023-08-11 |
rat |
| F S Lo, S M Lu, S M Sherma. Intracellular and extracellular in vivo recording of different response modes for relay cells of the cat's lateral geniculate nucleus. Experimental brain research. vol 83. issue 2. 1991-05-31. PMID:2022242. |
we also electrically stimulated the parabrachial region of the midbrain, which provides a mostly cholinergic innervation to the lateral geniculate nucleus. |
1991-05-31 |
2023-08-11 |
cat |
| S Brené, N Lindefors, M Herrera-Marschitz, H Persso. Expression of dopamine D2 receptor and choline acetyltransferase mRNA in the dopamine deafferented rat caudate-putamen. Experimental brain research. vol 83. issue 1. 1991-04-16. PMID:2150048. |
after a unilateral lesion of midbrain dopamine neurons, no change in the level of either d2r or chat mrna were seen in the large size intrinsic cholinergic neurons in caudate-putamen. |
1991-04-16 |
2023-08-11 |
rat |
| J V Lee, H C Akunne, K F Solima. Involvement of the brain cholinergic system in the rapid development of tolerance to glucose-induced analgesia. Archives internationales de pharmacodynamie et de therapie. vol 306. 1991-04-12. PMID:2076047. |
in an attempt to correlate changes in the cholinergic enzymes with glucose-induced analgesia, choline acetyltransferase and acetylcholinesterase activities were determined in the cerebral cortex, bulbus olfactorius, midbrain, hypothalamus, hippocampus, cerebellum, pons and medulla oblongata in control rats and rats treated with a single dose of glucose (10 g/kg) or two doses of glucose. |
1991-04-12 |
2023-08-11 |
rat |
| B Knüsel, J W Winslow, A Rosenthal, L E Burton, D P Seid, K Nikolics, F Heft. Promotion of central cholinergic and dopaminergic neuron differentiation by brain-derived neurotrophic factor but not neurotrophin 3. Proceedings of the National Academy of Sciences of the United States of America. vol 88. issue 3. 1991-03-08. PMID:1992488. |
to assess the selectivity of the effect of rhbdnf on cholinergic neurons, its actions were tested in cultures of ventral mesencephalon containing dopaminergic cells. |
1991-03-08 |
2023-08-11 |
human |
| A E Hallanger, S D Price, H J Lee, T L Steininger, B H Waine. Ultrastructure of cholinergic synaptic terminals in the thalamic anteroventral, ventroposterior, and dorsal lateral geniculate nuclei of the rat. The Journal of comparative neurology. vol 299. issue 4. 1990-12-28. PMID:2243163. |
the principal relay nuclei of the thalamus receive their cholinergic innervation from two midbrain cholinergic groups: the pedunculopontine tegmental nucleus and the laterodorsal tegmental nucleus. |
1990-12-28 |
2023-08-11 |
rat |
| N J Woolf, J B Harrison, J S Buchwal. Cholinergic neurons of the feline pontomesencephalon. II. Ascending anatomical projections. Brain research. vol 520. issue 1-2. 1990-11-14. PMID:2207647. |
a pontomesencephalic origin of cholinergic innervation to virtually every nucleus of the diencephalon, as well as to various midbrain and basal telencephalic sites was indicated in the cats with lesions, in which the optical density of chat-immunoreactivity was significantly decreased as compared to controls. |
1990-11-14 |
2023-08-11 |
cat |
| C G Frondoza, S Logan, G Forloni, J T Coyl. Production and characterization of monoclonal antibodies to N-acetyl-aspartyl-glutamate. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. vol 38. issue 4. 1990-04-30. PMID:2319120. |
these mab stained many nuclei of the medulla-pons and midbrain, mitral cells in the olfactory bulb, pyramidal neurons in sensorimotor cortex, locus ceruleus, and several cholinergic cranial nuclei. |
1990-04-30 |
2023-08-11 |
mouse |
| J S Buchwald, R J Erwin, S Read, D Van Lancker, J L Cumming. Midlatency auditory evoked responses: differential abnormality of P1 in Alzheimer's disease. Electroencephalography and clinical neurophysiology. vol 74. issue 5. 1989-10-19. PMID:2476296. |
this p1 abnormality suggests that the midbrain cholinergic cells in ad may be dysfunctional. |
1989-10-19 |
2023-08-11 |
human |
| K Niijima, M Yoshid. Activation of mesencephalic dopamine neurons by chemical stimulation of the nucleus tegmenti pedunculopontinus pars compacta. Brain research. vol 451. issue 1-2. 1989-07-31. PMID:3251582. |
these facts indicate: (1) the tpc-derived circling behavior is mediated by the dopamine system, (2) the chemical stimulation of tpc by ka might produce an activation of midbrain dopamine neurons by excitatory tpc efferents to the dopamine neurons and enhance the dopamine turnover in the nucleus accumbens as well as in the striatum, (3) the excitatory tpc efferents may be muscarinic cholinergic in accordance with previous reports. |
1989-07-31 |
2023-08-11 |
rat |
| E M Sorenson, D Parkinson, J L Dahl, V A Chiappinell. Immunohistochemical localization of choline acetyltransferase in the chicken mesencephalon. The Journal of comparative neurology. vol 281. issue 4. 1989-06-06. PMID:2708587. |
choline acetyltransferase, a specific marker for cholinergic neurons, has been immunohistochemically localized in the mesencephalon and in the caudal diencephalon of the chicken. |
1989-06-06 |
2023-08-11 |
rat |