| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Satoru Nakai, Tsuyoshi Hirose, Yasufumi Uwahodo, Takeshi Imaoka, Hiroshi Okazaki, Takashi Miwa, Masami Nakai, Sakiko Yamada, Bob Dunn, Kevin D Burris, Perry B Molinoff, Katsura Tottori, C Anthony Altar, Tetsuro Kikuch. Diminished catalepsy and dopamine metabolism distinguish aripiprazole from haloperidol or risperidone. European journal of pharmacology. vol 472. issue 1-2. 2004-04-23. PMID:12860477. |
catalepsy and changes in striatal and limbic dopamine metabolism were investigated in mice after oral administration of aripiprazole, haloperidol, and risperidone. |
2004-04-23 |
2023-08-12 |
mouse |
| Satoru Nakai, Tsuyoshi Hirose, Yasufumi Uwahodo, Takeshi Imaoka, Hiroshi Okazaki, Takashi Miwa, Masami Nakai, Sakiko Yamada, Bob Dunn, Kevin D Burris, Perry B Molinoff, Katsura Tottori, C Anthony Altar, Tetsuro Kikuch. Diminished catalepsy and dopamine metabolism distinguish aripiprazole from haloperidol or risperidone. European journal of pharmacology. vol 472. issue 1-2. 2004-04-23. PMID:12860477. |
the subtle effects of aripiprazole on striatal and limbic dopamine metabolism, and the decrease in catalepsy with chronic administration, illustrate fundamental differences in dopamine neurochemical actions and behavioral sequelae of aripiprazole compared to haloperidol or risperidone. |
2004-04-23 |
2023-08-12 |
mouse |
| Hitoshi Takahashi, Takio Sugita, Keizo Yoshida, Hisashi Higuchi, Tetsuo Shimiz. Effect of quetiapine in the treatment of panic attacks in patients with schizophrenia: 3 case reports. The Journal of neuropsychiatry and clinical neurosciences. vol 16. issue 1. 2004-04-05. PMID:14990767. |
the authors describe three schizophrenic patients who suffered from panic attacks and experienced marked improvement of these episodes after switching to quetiapine from their previous antipsychotics (haloperidol, bromperidol, and risperidone), which have high dopamine antagonistic properties such as haloperidol, bromperidol, and risperidone. |
2004-04-05 |
2023-08-12 |
Not clear |
| Patricia A Broderick, David N Rahni, Yueping Zho. Acute and subacute effects of risperidone and cocaine on accumbens dopamine and serotonin release using in vivo microvoltammetry on line with open-field behavior. Progress in neuro-psychopharmacology & biological psychiatry. vol 27. issue 6. 2004-01-05. PMID:14499322. |
acute and subacute effects of risperidone and cocaine on accumbens dopamine and serotonin release using in vivo microvoltammetry on line with open-field behavior. |
2004-01-05 |
2023-08-12 |
human |
| Kjell Erlandsson, Rodrigo A Bressan, Rachel S Mulligan, Peter J Ell, Vincent J Cunningham, Lyn S Pilowsk. Analysis of D2 dopamine receptor occupancy with quantitative SPET using the high-affinity ligand [123I]epidepride: resolving conflicting findings. NeuroImage. vol 19. issue 3. 2003-09-09. PMID:12880845. |
dopamine d(2) receptor occupancy by the atypical antipsychotic drug risperidone was evaluated. |
2003-09-09 |
2023-08-12 |
Not clear |
| Craig R Rush, William W Stoops, Lon R Hays, Paul E A Glaser, Lon S Hay. Risperidone attenuates the discriminative-stimulus effects of d-amphetamine in humans. The Journal of pharmacology and experimental therapeutics. vol 306. issue 1. 2003-07-24. PMID:12676890. |
after acquiring the discrimination (i.e., > or = 80% correct responding on four consecutive days), the effects of a range of doses of d-amphetamine (0, 2.5, 5, 10, and 15 mg), alone and after pretreatment with risperidone (0 and 1 mg), a d2 dopamine and 5-hydroxytryptamine (5-ht)2 serotonin antagonist, were assessed. |
2003-07-24 |
2023-08-12 |
Not clear |
| Hans O Kalkman, Erika Loetsche. alpha2C-Adrenoceptor blockade by clozapine and other antipsychotic drugs. European journal of pharmacology. vol 462. issue 1-3. 2003-07-02. PMID:12591093. |
therefore, the antagonistic potencies of the antipsychotics clozapine, chlorpromazine, risperidone, olanzapine, haloperidol, quetiapine, ziprasidone, iloperidone and aripiprazole were quantified using cell lines expressing the recombinant human alpha(2c)-adrenoceptor, alpha(2a)-adrenoceptor, or dopamine d(2l) receptor. |
2003-07-02 |
2023-08-12 |
human |
| Robert R Conley, Deanna L Kell. Current status of antipsychotic treatment. Current drug targets. CNS and neurological disorders. vol 1. issue 2. 2003-06-18. PMID:12769630. |
the second generation antipsychotics (sgas), clozapine, risperidone, olanzapine, quetiapine and ziprasidone all have relatively high serotonin to dopamine binding ratios. |
2003-06-18 |
2023-08-12 |
Not clear |
| Yoshito Kamijo, Kazui Soma, Tomonori Nagai, Katsuyoshi Kurihara, Takashi Ohwad. Acute massive pulmonary thromboembolism associated with risperidone and conventional phenothiazines. Circulation journal : official journal of the Japanese Circulation Society. vol 67. issue 1. 2003-06-13. PMID:12520151. |
in 5 cases, chlorpromazine and other phenothiazines had been prescribed, whereas in 2 cases, risperidone, a mixed serotonin 5ht(2a) and dopamine d(2) receptor antagonist, had been taken for 40 days and 6 days, respectively. |
2003-06-13 |
2023-08-12 |
Not clear |
| Junji Ichikawa, Zhu Li, Jin Dai, Herbert Y Meltze. Atypical antipsychotic drugs, quetiapine, iloperidone, and melperone, preferentially increase dopamine and acetylcholine release in rat medial prefrontal cortex: role of 5-HT1A receptor agonism. Brain research. vol 956. issue 2. 2003-04-22. PMID:12445705. |
preferential increases in both cortical dopamine (da) and acetylcholine (ach) release have been proposed to distinguish the atypical antipsychotic drugs (apds) clozapine, olanzapine, risperidone and ziprasidone from typical apds such as haloperidol. |
2003-04-22 |
2023-08-12 |
rat |
| G J E Schmitt, E M Meisenzahl, S Dresel, K Tatsch, B Rossmüller, T Frodl, U W Preuss, K Hahn, H J Mölle. Striatal dopamine D2 receptor binding of risperidone in schizophrenic patients as assessed by 123I-iodobenzamide SPECT: a comparative study with olanzapine. Journal of psychopharmacology (Oxford, England). vol 16. issue 3. 2003-04-07. PMID:12236625. |
striatal dopamine d2 receptor binding of risperidone in schizophrenic patients as assessed by 123i-iodobenzamide spect: a comparative study with olanzapine. |
2003-04-07 |
2023-08-12 |
human |
| Sathapana Kongsamut, Jiesheng Kang, Xiao-Liang Chen, Joachim Roehr, David Ramp. A comparison of the receptor binding and HERG channel affinities for a series of antipsychotic drugs. European journal of pharmacology. vol 450. issue 1. 2003-04-01. PMID:12176106. |
of the other drugs tested (ziprasidone, quetiapine, risperidone and olanzapine), olanzapine displayed the greatest selectivity for dopamine d(2) and 5-ht(2a) receptor binding (100-1000-fold) compared to its herg channel ic(50). |
2003-04-01 |
2023-08-12 |
human |
| Miyuki Ota, Keiji Mori, Akira Nakashima, Yoko S Kaneko, Kentaro Fujiwara, Mitsuyasu Itoh, Akio Nagasaka, Akira Ot. Peripheral injection of risperidone, an atypical antipsychotic, alters the bodyweight gain of rats. Clinical and experimental pharmacology & physiology. vol 29. issue 11. 2003-03-05. PMID:12366389. |
risperidone is an atypical antipsychotic drug that possesses 5-hydroxytryptamine 5-ht2 receptor antagonism combined with milder dopamine d2 receptor antagonism. |
2003-03-05 |
2023-08-12 |
rat |
| Junji Ichikawa, Young Chul Chung, Zhu Li, Jin Dai, Herbert Y Meltze. Cholinergic modulation of basal and amphetamine-induced dopamine release in rat medial prefrontal cortex and nucleus accumbens. Brain research. vol 958. issue 1. 2003-02-25. PMID:12468043. |
since atypical apds such as clozapine, olanzapine, risperidone, ziprasidone and quetiapine, increase brain acetylcholine as well as dopamine (da) release in a region-specific manner, their effects on cholinergic and dopaminergic neurotransmission may also contribute to various actions of these drugs. |
2003-02-25 |
2023-08-12 |
rat |
| Norio Yasui-Furukori, Tsuyoshi Kondo, Akihito Suzuki, Kazuo Mihara, Sunao Kanek. Comparison of prolactin concentrations between haloperidol and risperidone treatments in the same female patients with schizophrenia. Psychopharmacology. vol 162. issue 1. 2003-01-02. PMID:12107619. |
however, from a purely pharmacological point of view, prolactin response per drug concentration was more sensitive during haloperidol treatment than risperidone treatment, probably resulting from the potent and selective antagonistic effect of haloperidol on dopamine d(2) receptor, compared with the broader pharmacological spectrum of risperidone. |
2003-01-02 |
2023-08-12 |
human |
| Stephen R Wachtel, Amanda Ortengren, Harriet de Wi. The effects of acute haloperidol or risperidone on subjective responses to methamphetamine in healthy volunteers. Drug and alcohol dependence. vol 68. issue 1. 2002-11-05. PMID:12167550. |
the goal of this study was to examine the effects of haloperidol, a drug that primarily blocks dopamine receptors, and risperidone, a drug that blocks both dopamine and serotonin receptors, on the physiological and subjective effects of methamphetamine in healthy volunteers. |
2002-11-05 |
2023-08-12 |
human |
| A Baghdadli, V Gonnier, C Aussillou. [Review of psychopharmacological treatments in adolescents and adults with autistic disorders]. L'Encephale. vol 28. issue 3 Pt 1. 2002-10-29. PMID:12091786. |
risperidone (dopamine and serotonine antagonist): among several studies only few have been controlled. |
2002-10-29 |
2023-08-12 |
Not clear |
| Yasuhiko Yamada, Yoshiyuki Ohno, Yoshifumi Nakashima, Masato Fukuda, Risa Takayanagi, Hitoshi Sato, Fumito Tsuchiya, Yasufumi Sawada, Tatsuji Ig. Prediction and assessment of extrapyramidal side effects induced by risperidone based on dopamine D(2) receptor occupancy. Synapse (New York, N.Y.). vol 46. issue 1. 2002-10-16. PMID:12211096. |
prediction and assessment of extrapyramidal side effects induced by risperidone based on dopamine d(2) receptor occupancy. |
2002-10-16 |
2023-08-12 |
Not clear |
| Yasuhiko Yamada, Yoshiyuki Ohno, Yoshifumi Nakashima, Masato Fukuda, Risa Takayanagi, Hitoshi Sato, Fumito Tsuchiya, Yasufumi Sawada, Tatsuji Ig. Prediction and assessment of extrapyramidal side effects induced by risperidone based on dopamine D(2) receptor occupancy. Synapse (New York, N.Y.). vol 46. issue 1. 2002-10-16. PMID:12211096. |
in the present study, we attempted to predict the risk of extrapyramidal side effects of a selective monoaminergic antagonist, risperidone, by analyzing the correlation between the dopamine d(2) receptor occupancy and the degree of extrapyramidal side effects of the drug. |
2002-10-16 |
2023-08-12 |
Not clear |
| Jenifer S Hoy, Bruce Alexande. Rabbit syndrome secondary to risperidone. Pharmacotherapy. vol 22. issue 4. 2002-10-11. PMID:11939686. |
this uncommon extrapyramidal side effect is characterized by rhythmic movements of the mouth and may be caused by typical antipsychotics and risperidone secondary to blockade of dopamine d2 receptors. |
2002-10-11 |
2023-08-12 |
rabbit |