| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lesley J Scott, Sohita Dhillo. Risperidone: a review of its use in the treatment of irritability associated with autistic disorder in children and adolescents. Paediatric drugs. vol 9. issue 5. 2008-01-11. PMID:17927305. |
risperidone (risperdal), a psychotropic atypical antipsychotic agent, is thought to act via dopamine d(2) and serotonin (5-ht [5-hydroxytryptamine])(2a) receptor antagonism. |
2008-01-11 |
2023-08-12 |
Not clear |
| Dayong Wang, Yukihiro Noda, Yuan Zhou, Atsumi Nitta, Hiroshi Furukawa, Toshitaka Nabeshim. Synergistic effect of combined treatment with risperidone and galantamine on phencyclidine-induced impairment of latent visuospatial learning and memory: Role of nAChR activation-dependent increase of dopamine D1 receptor-mediated neurotransmission. Neuropharmacology. vol 53. issue 3. 2007-12-06. PMID:17632185. |
synergistic effect of combined treatment with risperidone and galantamine on phencyclidine-induced impairment of latent visuospatial learning and memory: role of nachr activation-dependent increase of dopamine d1 receptor-mediated neurotransmission. |
2007-12-06 |
2023-08-12 |
mouse |
| Dayong Wang, Yukihiro Noda, Yuan Zhou, Atsumi Nitta, Hiroshi Furukawa, Toshitaka Nabeshim. Synergistic effect of combined treatment with risperidone and galantamine on phencyclidine-induced impairment of latent visuospatial learning and memory: Role of nAChR activation-dependent increase of dopamine D1 receptor-mediated neurotransmission. Neuropharmacology. vol 53. issue 3. 2007-12-06. PMID:17632185. |
combined treatment with galantamine and risperidone, at low, ineffective doses (both at 0.05 mg/kg) showed a synergistic effect to reverse cognitive impairment and increase extracellular concentration of dopamine in the mpfc. |
2007-12-06 |
2023-08-12 |
mouse |
| Dayong Wang, Yukihiro Noda, Yuan Zhou, Atsumi Nitta, Hiroshi Furukawa, Toshitaka Nabeshim. Synergistic effect of combined treatment with risperidone and galantamine on phencyclidine-induced impairment of latent visuospatial learning and memory: Role of nAChR activation-dependent increase of dopamine D1 receptor-mediated neurotransmission. Neuropharmacology. vol 53. issue 3. 2007-12-06. PMID:17632185. |
the study indicates that galantamine and risperidone may have synergistic effect on the cognitive impairments in schizophrenia patients by synergistically promoting the nachr activation-dependent increase of dopamine d1 receptor-mediated neurotransmission. |
2007-12-06 |
2023-08-12 |
mouse |
| Shaun Jordan, Karen Regardie, Janelle L Johnson, Ruoyan Chen, Junichi Kambayashi, Robert McQuade, Hisashi Kitagawa, Yoshihiro Tadori, Tetsuro Kikuch. In vitro functional characteristics of dopamine D2 receptor partial agonists in second and third messenger-based assays of cloned human dopamine D2Long receptor signalling. Journal of psychopharmacology (Oxford, England). vol 21. issue 6. 2007-10-18. PMID:17092971. |
these drug effects on ca(2+) mobilization and erk2 phosphoprotein expression were mediated through dopamine hd(2l) receptors, as they all were blocked by (-)raclopride, whereas (-)raclopride and other dopamine d(2) receptor antagonists (haloperidol, risperidone, ziprasidone, olanzapine, clozapine and quetiapine) were inactive on their own in both assays. |
2007-10-18 |
2023-08-12 |
human |
| Taylor Moran-Gates, Christopher Grady, Young Shik Park, Ross J Baldessarini, Frank I Taraz. Effects of risperidone on dopamine receptor subtypes in developing rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 17. issue 6-7. 2007-06-13. PMID:17175142. |
accordingly, we studied the effects of repeated treatment of risperidone on dopamine receptors in brain regions of juvenile rat. |
2007-06-13 |
2023-08-12 |
rat |
| Taylor Moran-Gates, Christopher Grady, Young Shik Park, Ross J Baldessarini, Frank I Taraz. Effects of risperidone on dopamine receptor subtypes in developing rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 17. issue 6-7. 2007-06-13. PMID:17175142. |
levels of dopamine receptors (d(1), d(2), d(3), d(4)) in forebrain regions of juvenile rats were quantified after 3 weeks of treatment with three different doses of risperidone (0.3, 1.0 and 3.0 mg/kg) and compared findings to those in adult rats treated with risperidone (3.0 mg/kg/day) previously. |
2007-06-13 |
2023-08-12 |
rat |
| Taylor Moran-Gates, Christopher Grady, Young Shik Park, Ross J Baldessarini, Frank I Taraz. Effects of risperidone on dopamine receptor subtypes in developing rat brain. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 17. issue 6-7. 2007-06-13. PMID:17175142. |
the findings indicate dose-dependent effects of risperidone on dopamine receptors in developing animals, and that juvenile animals are more sensitive than adults to the cerebral effects of risperidone. |
2007-06-13 |
2023-08-12 |
rat |
| Dayong Wang, Yukihiro Noda, Yuan Zhou, Atsumi Nitta, Hiroshi Furukawa, Toshitaka Nabeshim. Synergistic effect of galantamine with risperidone on impairment of social interaction in phencyclidine-treated mice as a schizophrenic animal model. Neuropharmacology. vol 52. issue 4. 2007-06-01. PMID:17313962. |
at non-effective doses by themselves, co-administration of galantamine (0.05mg/kg) and risperidone (0.05mg/kg) showed synergistic effects on pcp-induced impairments of social interaction and dopamine release in the medial prefrontal cortex (mpfc). |
2007-06-01 |
2023-08-12 |
mouse |
| Dayong Wang, Yukihiro Noda, Yuan Zhou, Atsumi Nitta, Hiroshi Furukawa, Toshitaka Nabeshim. Synergistic effect of galantamine with risperidone on impairment of social interaction in phencyclidine-treated mice as a schizophrenic animal model. Neuropharmacology. vol 52. issue 4. 2007-06-01. PMID:17313962. |
we conclude that galantamine may have synergistic effect with risperidone on the negative symptom of social withdrawal in schizophrenia, which is mediated by dopamine-d(1) receptors in the mpfc through nachr activation-increased dopamine release. |
2007-06-01 |
2023-08-12 |
mouse |
| Maiko Sato, Yukio Ago, Ken Koda, Shigeo Nakamura, Toshiyuki Kawasaki, Akemichi Baba, Toshio Matsud. Role of postsynaptic serotonin1A receptors in risperidone-induced increase in acetylcholine release in rat prefrontal cortex. European journal of pharmacology. vol 559. issue 2-3. 2007-05-09. PMID:17258195. |
on the other hand, local application of risperidone (3 and 10 microm), the 5-ht1a receptor agonist 8-hydroxy-2-(di-n-propylamino)tetralin (1 and 10 microm), and the dopamine d4 receptor antagonist 3-(4-(4-iodophenyl)piperazine-1-yl)methyl-1h-pyrrolo[2,3-b]pyridine (1 and 10 microm) into the cortex did not affect acetylcholine release in the prefrontal cortex. |
2007-05-09 |
2023-08-12 |
rat |
| P Murali Doraiswamy, Gisela Schott, Kristina Star, Ralph Edwards, Bruno Mueller-Oerlinghause. Atypical antipsychotics and pituitary neoplasms in the WHO database. Psychopharmacology bulletin. vol 40. issue 1. 2007-05-02. PMID:17285098. |
amisulpride and risperidone are potent dopamine d2 receptor blocking atypical antipsychotics that can cause hyperprolactinemia. |
2007-05-02 |
2023-08-12 |
mouse |
| Pietro Gareri, Pasquale De Fazio, Salvatore De Fazio, Norma Marigliano, Guido Ferreri Ibbadu, Giovambattista De Sarr. Adverse effects of atypical antipsychotics in the elderly: a review. Drugs & aging. vol 23. issue 12. 2007-05-01. PMID:17154659. |
new antipsychotics, such as amisulpride, clozapine, olanzapine, risperidone, quetiapine, ziprasidone, zotepine and aripiprazole, may interact with both dopamine and serotonin receptors. |
2007-05-01 |
2023-08-12 |
Not clear |
| Shinya Uchida, Yasuhiro Kato, Kazufumi Hirano, Yoshiyuki Kagawa, Shizuo Yamad. Brain neurotransmitter receptor-binding characteristics in rats after oral administration of haloperidol, risperidone and olanzapine. Life sciences. vol 80. issue 17. 2007-05-01. PMID:17316700. |
the present study was conducted to characterize the binding of neurotransmitter receptors (dopamine d(2), serotonin 5-ht(2), histamine h(1), adrenaline alpha(1) and muscarine m(l) receptors) in the rat's brain after the oral administration of haloperidol, risperidone, and olanzapine. |
2007-05-01 |
2023-08-12 |
rat |
| Mahendra Bishnoi, Anil Kumar, Kanwaljit Chopra, Shrinivas K Kulkarn. Comparative neurochemical changes associated with chronic administration of typical and atypical neuroleptics: implications in tardive dyskinesia. Indian journal of experimental biology. vol 45. issue 2. 2007-04-10. PMID:17375557. |
chronic administration of atypical neuroleptics clozapine and risperidone resulted in the decrease in extracellular concentration of dopamine and norepinephrine but the effect was less significant as compared to typical drugs. |
2007-04-10 |
2023-08-12 |
rat |
| M Reimold, C Solbach, S Noda, J-E Schaefer, M Bartels, M Beneke, H-J Machulla, R Bares, T Glaser, H Wormstal. Occupancy of dopamine D(1), D (2) and serotonin (2A) receptors in schizophrenic patients treated with flupentixol in comparison with risperidone and haloperidol. Psychopharmacology. vol 190. issue 2. 2007-03-30. PMID:17111172. |
occupancy of dopamine d(1), d (2) and serotonin (2a) receptors in schizophrenic patients treated with flupentixol in comparison with risperidone and haloperidol. |
2007-03-30 |
2023-08-12 |
Not clear |
| M Reimold, C Solbach, S Noda, J-E Schaefer, M Bartels, M Beneke, H-J Machulla, R Bares, T Glaser, H Wormstal. Occupancy of dopamine D(1), D (2) and serotonin (2A) receptors in schizophrenic patients treated with flupentixol in comparison with risperidone and haloperidol. Psychopharmacology. vol 190. issue 2. 2007-03-30. PMID:17111172. |
in vitro data show comparable affinity to dopamine d(2), d(1) and 5-ht(2a) receptors and recently, flx showed to be not inferior to risperidone in schizophrenic patients with predominant negative symptomatology, which was implicated with flupentixol's interaction with 5-ht(2a) and/or d(1) receptors. |
2007-03-30 |
2023-08-12 |
Not clear |
| Ana M Catafau, Iluminada Corripio, Victor Pérez, Juan Carlos Martin, Alain Schotte, Ignasi Carrió, Enric Alvare. Dopamine D2 receptor occupancy by risperidone: implications for the timing and magnitude of clinical response. Psychiatry research. vol 148. issue 2-3. 2007-02-12. PMID:17059881. |
dopamine d2 receptor occupancy by risperidone: implications for the timing and magnitude of clinical response. |
2007-02-12 |
2023-08-12 |
Not clear |
| Ana M Catafau, Iluminada Corripio, Victor Pérez, Juan Carlos Martin, Alain Schotte, Ignasi Carrió, Enric Alvare. Dopamine D2 receptor occupancy by risperidone: implications for the timing and magnitude of clinical response. Psychiatry research. vol 148. issue 2-3. 2007-02-12. PMID:17059881. |
the objective of the study is to investigate whether dopamine d2 receptor occupancy by risperidone and plasma levels over time can account for therapeutic efficacy and the latency period to response. |
2007-02-12 |
2023-08-12 |
Not clear |
| Dineshree V Naiker, Stanley V Catts, Vibeke S Catts, Kuldip S Bedi, Lesley J Bryan-Lluk. Dose determination of haloperidol, risperidone and olanzapine using an in vivo dopamine D2-receptor occupancy method in the rat. European journal of pharmacology. vol 540. issue 1-3. 2006-12-11. PMID:16730699. |
dose determination of haloperidol, risperidone and olanzapine using an in vivo dopamine d2-receptor occupancy method in the rat. |
2006-12-11 |
2023-08-12 |
rat |