| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ming-Ling Wu, Jou-Fang Den. Serotonin toxicity caused by moclobemide too soon after paroxetine-selegiline. Journal of the Chinese Medical Association : JCMA. vol 72. issue 8. 2009-12-09. PMID:19687003. |
after moclobemide was prescribed in place of paroxetine without a washout period, she quickly developed confusion, agitation, ataxia, diaphoresis, tremor, mydriasis, ocular clonus, hyperreflexia, tachycardia, moderately elevated blood pressure and high fever, symptoms that were consistent with serotonin toxicity. |
2009-12-09 |
2023-08-12 |
Not clear |
| Ming-Ling Wu, Jou-Fang Den. Serotonin toxicity caused by moclobemide too soon after paroxetine-selegiline. Journal of the Chinese Medical Association : JCMA. vol 72. issue 8. 2009-12-09. PMID:19687003. |
this case demonstrates that serotonin toxicity may occur even with small doses of paroxetine, selegiline and moclobemide in combination. |
2009-12-09 |
2023-08-12 |
Not clear |
| Terje Vasskog, Ove Bergersen, Trude Anderssen, Einar Jensen, Trine Egge. Depletion of selective serotonin reuptake inhibitors during sewage sludge composting. Waste management (New York, N.Y.). vol 29. issue 11. 2009-11-12. PMID:19595585. |
sewage and sewage sludge is known to contain pharmaceuticals, and since sewage sludge is often used as fertilizer within agriculture, the reduction of the selective serotonin reuptake inhibitors (ssris) citalopram, sertraline, paroxetine, fluvoxamine and fluoxetine during composting has been investigated. |
2009-11-12 |
2023-08-12 |
Not clear |
| Reiji Yoshimura, Wakako Umene-Nakano, Akihito Suzuki, Nobuhisa Ueda, Kyoko Miyamoto, Atsuko Ikenouchi-Sugita, Hikaru Hori, Koichi Otani, Jun Nakamur. Rapid response to paroxetine is associated with plasma paroxetine levels at 4 but not 8 weeks of treatment, and is independent of serotonin transporter promoter polymorphism in Japanese depressed patients. Human psychopharmacology. vol 24. issue 6. 2009-10-20. PMID:19606452. |
rapid response to paroxetine is associated with plasma paroxetine levels at 4 but not 8 weeks of treatment, and is independent of serotonin transporter promoter polymorphism in japanese depressed patients. |
2009-10-20 |
2023-08-12 |
Not clear |
| Reiji Yoshimura, Wakako Umene-Nakano, Akihito Suzuki, Nobuhisa Ueda, Kyoko Miyamoto, Atsuko Ikenouchi-Sugita, Hikaru Hori, Koichi Otani, Jun Nakamur. Rapid response to paroxetine is associated with plasma paroxetine levels at 4 but not 8 weeks of treatment, and is independent of serotonin transporter promoter polymorphism in Japanese depressed patients. Human psychopharmacology. vol 24. issue 6. 2009-10-20. PMID:19606452. |
in the present study, we investigated the relationship between the serotonin transporter gene linked polymorphic regions (5-httlpr) or plasma paroxetine levels and clinical response to paroxetine in depressed patients. |
2009-10-20 |
2023-08-12 |
Not clear |
| Fibromyalgia: poorly understood; treatments are disappointing. Prescrire international. vol 18. issue 102. 2009-09-28. PMID:19746561. |
the efficacy of selective serotonin reuptake inhibitor antidepressants (fluoxetine, paroxetine and citalopram), serotonin and nonadrenaline reuptake inhibitors (duloxetine and milnacipran) is even less well established. |
2009-09-28 |
2023-08-12 |
Not clear |
| Kush Patel, Wayne J G Hellstro. Central regulation of ejaculation and the therapeutic role of serotonergic agents in premature ejaculation. Current opinion in investigational drugs (London, England : 2000). vol 10. issue 7. 2009-09-22. PMID:19579174. |
the process of ejaculation is under central control, and serotonin (5-ht) is a key mediator; therefore, ssris and tricyclic antidepressants, including paroxetine, sertraline and clomipramine, are commonly used with chronic daily dosing in the treatment of pe. |
2009-09-22 |
2023-08-12 |
Not clear |
| Tierney K Ahrold, Cindy M Mesto. Effects of SNS activation on SSRI-induced sexual side effects differ by SSRI. Journal of sex & marital therapy. vol 35. issue 4. 2009-08-04. PMID:19466669. |
as predicted, women taking ssris, which are highly selective for 5ht(ia) (sertraline, paroxetine), showed improvement in sexual arousal and orgasm. |
2009-08-04 |
2023-08-12 |
Not clear |
| Johnny S W Chan, Deog Joong Kim, Chang Ho Ahn, Ronald S Oosting, Berend Olivie. Clavulanic acid stimulates sexual behaviour in male rats. European journal of pharmacology. vol 609. issue 1-3. 2009-07-13. PMID:19285063. |
to characterize these pro-sexual activities, clavulanic acid was tested in three doses and compared to one dose of a sexually inhibitory dose of the selective serotonin reuptake inhibitor, paroxetine, in sexually-experienced male rats, selected for a moderate level of sexual performance in a standard 30-min test with an oestrus female. |
2009-07-13 |
2023-08-12 |
human |
| Jonathan Shelton, Pascal Bonaventure, Xiaorong Li, Sujin Yun, Timothy Lovenberg, Christine Dugovi. 5-HT7 receptor deletion enhances REM sleep suppression induced by selective serotonin reuptake inhibitors, but not by direct stimulation of 5-HT1A receptor. Neuropharmacology. vol 56. issue 2. 2009-07-01. PMID:18948124. |
three ssris (citalopram, fluoxetine and paroxetine) but not the tricyclic antidepressant desipramine had a significantly stronger rem sleep suppressive effect in 5-ht(7)(-/-) mice compared to 5-ht(7)(+/+) mice. |
2009-07-01 |
2023-08-12 |
mouse |
| Fili Fazzino, Mary Urbina, Nemesio Cedeño, Lucimey Lim. Fluoxetine treatment to rats modifies serotonin transporter and cAMP in lymphocytes, CD4+ and CD8+ subpopulations and interleukins 2 and 4. International immunopharmacology. vol 9. issue 4. 2009-06-25. PMID:19189865. |
serotonin transporter was also labeled with [(3)h]paroxetine, specific binding defined with imipramine. |
2009-06-25 |
2023-08-12 |
rat |
| Fili Fazzino, Mary Urbina, Nemesio Cedeño, Lucimey Lim. Fluoxetine treatment to rats modifies serotonin transporter and cAMP in lymphocytes, CD4+ and CD8+ subpopulations and interleukins 2 and 4. International immunopharmacology. vol 9. issue 4. 2009-06-25. PMID:19189865. |
fluoxetine significantly increased the number of lymphocytes expressing serotonin transporter and elevated the binding of [(3)h]paroxetine. |
2009-06-25 |
2023-08-12 |
rat |
| Cecilie L Licht, Anders B Marcussen, Gregers Wegener, David H Overstreet, Susana Aznar, Gitte M Knudse. The brain 5-HT4 receptor binding is down-regulated in the Flinders Sensitive Line depression model and in response to paroxetine administration. Journal of neurochemistry. vol 109. issue 5. 2009-06-15. PMID:19476548. |
we also determined the regulation of 5-ht(4) receptor binding by 1, 14, and 21 days of paroxetine administration and subchronic 5-ht depletion, and compared this with changes in 5-ht(2a) receptor [(3)h]mdl100907 binding. |
2009-06-15 |
2023-08-12 |
rat |
| Cecilie L Licht, Anders B Marcussen, Gregers Wegener, David H Overstreet, Susana Aznar, Gitte M Knudse. The brain 5-HT4 receptor binding is down-regulated in the Flinders Sensitive Line depression model and in response to paroxetine administration. Journal of neurochemistry. vol 109. issue 5. 2009-06-15. PMID:19476548. |
chronic but not acute paroxetine administration caused a 16-47% down-regulation of 5-ht(4) receptor binding in all regions evaluated including the basal ganglia and hippocampus, while 5-ht depletion increased the 5-ht(4) receptor binding in the dorsal hippocampus, hypothalamus, and lateral globus pallidus. |
2009-06-15 |
2023-08-12 |
rat |
| Cecilie L Licht, Anders B Marcussen, Gregers Wegener, David H Overstreet, Susana Aznar, Gitte M Knudse. The brain 5-HT4 receptor binding is down-regulated in the Flinders Sensitive Line depression model and in response to paroxetine administration. Journal of neurochemistry. vol 109. issue 5. 2009-06-15. PMID:19476548. |
in comparison, the 5-ht(2a) receptor binding was decreased in the frontal and cingulate cortices after chronic paroxetine administration, and markedly reduced in several regions after 5-ht depletion. |
2009-06-15 |
2023-08-12 |
rat |
| Cecilie L Licht, Anders B Marcussen, Gregers Wegener, David H Overstreet, Susana Aznar, Gitte M Knudse. The brain 5-HT4 receptor binding is down-regulated in the Flinders Sensitive Line depression model and in response to paroxetine administration. Journal of neurochemistry. vol 109. issue 5. 2009-06-15. PMID:19476548. |
thus, the 5-ht(4) receptor binding was decreased in the flinders sensitive line depression model and in response to chronic paroxetine administration. |
2009-06-15 |
2023-08-12 |
rat |
| Kristin Watson, Kelly M Summer. Depression in patients with heart failure: clinical implications and management. Pharmacotherapy. vol 29. issue 1. 2009-06-02. PMID:19113796. |
if treatment includes pharmacologic strategies, selective serotonin reuptake inhibitors (especially paroxetine and sertraline), mirtazapine, and nefazodone have the strongest efficacy evidence in this population. |
2009-06-02 |
2023-08-12 |
Not clear |
| Ting-Ting Chang, Chhian-Hui Lêng, Jo Yung-Wei Wu, Sheng-Yu Lee, Yu-Shan Wang, Yi-Chyan Chen, Ru-Band L. Lower side effects of milnacipran than paroxetine in the treatment of major depression disorder among Han Chinese in Taiwan. The Chinese journal of physiology. vol 51. issue 6. 2009-05-29. PMID:19280883. |
the present study compares milnacipran with paroxetine, a selective serotonin reuptake inhibitor (ssri) and which has been used clinically for years to evaluate the efficacy, patient tolerance, and side effects in the treatment of major depression. |
2009-05-29 |
2023-08-12 |
human |
| Toshiyuki Yasui, Masayo Yamada, Hirokazu Uemura, Shu-Ichi Ueno, Shusuke Numata, Tetsuro Ohmori, Naoko Tsuchiya, Masamichi Noguchi, Mitsutoshi Yuzurihara, Yoshio Kase, Minoru Irahar. Changes in circulating cytokine levels in midlife women with psychological symptoms with selective serotonin reuptake inhibitor and Japanese traditional medicine. Maturitas. vol 62. issue 2. 2009-05-06. PMID:19179025. |
the aim of the present study was to compare the effects on serum cytokine concentrations of paroxetine, a selective serotonin re-uptake inhibitor, and kamishoyosan, a japanese traditional medicine, in midlife women with psychological symptoms. |
2009-05-06 |
2023-08-12 |
Not clear |
| Gwenn S Smith, Charles F Reynolds, Patricia R Houck, Mary Amanda Dew, Joshua Ginsberg, Yilong Ma, Benoit H Mulsant, Bruce G Polloc. Cerebral glucose metabolic response to combined total sleep deprivation and antidepressant treatment in geriatric depression: a randomized, placebo-controlled study. Psychiatry research. vol 171. issue 1. 2009-04-29. PMID:19087899. |
a randomized, placebo-controlled study was performed to evaluate whether the onset of the glucose metabolic effects of a selective serotonin reuptake inhibitor (paroxetine) would be accelerated by total sleep deprivation (tsd). |
2009-04-29 |
2023-08-12 |
human |