| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Raymond Mongeau, Cédric B P Martin, Caroline Chevarin, Rafael Maldonado, Michel Hamon, Patricia Robledo, Laurence Lanfume. 5-HT2C receptor activation prevents stress-induced enhancement of brain 5-HT turnover and extracellular levels in the mouse brain: modulation by chronic paroxetine treatment. Journal of neurochemistry. vol 115. issue 2. 2010-11-22. PMID:20796171. |
chronic paroxetine prevented both the anxiogenic effect of m-chlorophenylpiperazine and the inhibitory effect of ro 60-0175 on locomotion and stress-induced increase in 5-ht turnover. |
2010-11-22 |
2023-08-12 |
mouse |
| Raymond Mongeau, Cédric B P Martin, Caroline Chevarin, Rafael Maldonado, Michel Hamon, Patricia Robledo, Laurence Lanfume. 5-HT2C receptor activation prevents stress-induced enhancement of brain 5-HT turnover and extracellular levels in the mouse brain: modulation by chronic paroxetine treatment. Journal of neurochemistry. vol 115. issue 2. 2010-11-22. PMID:20796171. |
the anxiolytic action of chronic paroxetine might be associated with an enhancement of 5-ht neurotransmission caused by a decreased 5-ht(2c) receptor-mediated inhibition of stress-induced increase in 5-ht release. |
2010-11-22 |
2023-08-12 |
mouse |
| Plinio C Casarotto, Felipe V Gomes, Leonardo B M Resstel, Francisco S Guimarãe. Cannabidiol inhibitory effect on marble-burying behaviour: involvement of CB1 receptors. Behavioural pharmacology. vol 21. issue 4. 2010-11-04. PMID:20695034. |
a similar, although larger, decrease was also found after the serotonin selective reuptake inhibitor paroxetine (10 mg/kg, 77% decrease) and the benzodiazepine diazepam (2.5 mg/kg, 84% decrease). |
2010-11-04 |
2023-08-12 |
mouse |
| Vânia R Sela, Camila M Roncon, Hélio Zangrossi, Frederico G Graeff, Elisabeth A Aud. Pindolol potentiates the panicolytic effect of paroxetine in the elevated T-maze. Life sciences. vol 87. issue 13-14. 2010-10-15. PMID:20816996. |
the aim of this study was to examine the interaction between pindolol and the selective serotonin reuptake inhibitor (ssri), paroxetine in rats submitted to the elevated t-maze (etm). |
2010-10-15 |
2023-08-12 |
rat |
| Bibiana M Gay, Marina Prigol, André L Stein, Cristina W Nogueir. Antidepressant-like pharmacological profile of 3-(4-fluorophenylselenyl)-2,5-diphenylselenophene: Involvement of serotonergic system. Neuropharmacology. vol 59. issue 3. 2010-10-14. PMID:20488195. |
the antidepressant-like effect of combined treatment with subeffetive doses of dps and paroxetine, a selective serotonin reuptake inhibitor (ssri) was investigated. |
2010-10-14 |
2023-08-12 |
mouse |
| Thomas I F H Cremers, Eliyahu Dremencov, Fokko J Bosker, Ben H C Westerin. Oxazepam and temazepam attenuate paroxetine-induced elevation of serotonin levels in guinea-pig hippocampus. The international journal of neuropsychopharmacology. vol 13. issue 6. 2010-09-29. PMID:20047712. |
it was found that the acute systemic administration of paroxetine increased extracellular 5-ht levels. |
2010-09-29 |
2023-08-12 |
Not clear |
| Charles Hutchison Keesor West, James Carl Ritchie, Jay Michael Weis. Paroxetine-induced increase in activity of locus coeruleus neurons in adolescent rats: implication of a countertherapeutic effect of an antidepressant. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 35. issue 8. 2010-09-17. PMID:20357759. |
the concern that antidepressant (ad) drugs, especially selective serotonin reuptake inhibitors and paroxetine (par) in particular, can increase suicidality during the early treatment of juvenile patients (children and adolescents) has created a dilemma for clinicians treating depressives. |
2010-09-17 |
2023-08-12 |
rat |
| Mine Kadioglu, Efnan Muci, Rasin Ozyavuz, Ersin Yaris, Murat Kesim, Nuri I Kalyonc. Paroxetine inhibited the relaxations induced by EFS in mice corpus cavernosum: is it a NOS inhibition? Fundamental & clinical pharmacology. vol 24. issue 1. 2010-08-16. PMID:19702694. |
selective serotonin reuptake inhibitors are used in the treatment of psychiatric disorders but are associated with high incidence of sexual dysfunction such as ejaculation disorders by sertraline and fluoxetine, erection disorders by paroxetine. |
2010-08-16 |
2023-08-12 |
mouse |
| V Sawhney, G Thomas, P Webster, R Schillin. Resolution of Brugada-pattern ECG after withdrawal of the selective serotonin reuptake inhibitor paroxetine. Heart (British Cardiac Society). vol 96. issue 14. 2010-08-16. PMID:20478856. |
resolution of brugada-pattern ecg after withdrawal of the selective serotonin reuptake inhibitor paroxetine. |
2010-08-16 |
2023-08-12 |
Not clear |
| F Brambilla, R Dalle Grave, S Calugi, G Marchesini, S Baroni, D Marazzit. Effects of cognitive-behavioral therapy on Eating Disorders: neurotransmitter secretory response to treatment. Psychoneuroendocrinology. vol 35. issue 5. 2010-08-10. PMID:19962832. |
the aim of the study was to see whether or not cbt modifies the secretion of central da (blood homovanillic acid=hva), ne (blood 3-methoxy-4-hydroxy-phenylglycol=mhpg) and the 5-ht transporter (as evaluated by the platelet paroxetine binding=[(3)h]-par-binding), if the physical and psychological effects of cbt correlate with changes of the neurotransmitter secretion; and if the biological effects of cbt are linked to specific psychopathological aspect of the disorders. |
2010-08-10 |
2023-08-12 |
Not clear |
| Young-Min Park, Yeon-Kyung Jun. Manic switch and serotonin syndrome induced by augmentation of paroxetine with methylphenidate in a patient with major depression. Progress in neuro-psychopharmacology & biological psychiatry. vol 34. issue 4. 2010-07-30. PMID:20298736. |
manic switch and serotonin syndrome induced by augmentation of paroxetine with methylphenidate in a patient with major depression. |
2010-07-30 |
2023-08-12 |
Not clear |
| Cecilie Löe Licht, Gitte Moos Knudsen, Trevor Shar. Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels. Neuroscience letters. vol 476. issue 2. 2010-07-30. PMID:20381585. |
effects of the 5-ht(4) receptor agonist rs67333 and paroxetine on hippocampal extracellular 5-ht levels. |
2010-07-30 |
2023-08-12 |
rat |
| Cecilie Löe Licht, Gitte Moos Knudsen, Trevor Shar. Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels. Neuroscience letters. vol 476. issue 2. 2010-07-30. PMID:20381585. |
this microdialysis study evaluated the effect of the 5-ht(4) receptor agonist, rs67333, on extracellular serotonin (5-hydroxytryptamine, 5-ht) and 5-hiaa levels in rat ventral hippocampus during chloral hydrate anaesthesia, and explored the ability of rs67333 to augment the effect of the selective serotonin reuptake inhibitor paroxetine. |
2010-07-30 |
2023-08-12 |
rat |
| Cecilie Löe Licht, Gitte Moos Knudsen, Trevor Shar. Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels. Neuroscience letters. vol 476. issue 2. 2010-07-30. PMID:20381585. |
had no effect on extracellular 5-ht or 5-hiaa levels, while acute paroxetine (0.5mg/kg i.v.) |
2010-07-30 |
2023-08-12 |
rat |
| Cecilie Löe Licht, Gitte Moos Knudsen, Trevor Shar. Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels. Neuroscience letters. vol 476. issue 2. 2010-07-30. PMID:20381585. |
administration of rs67333 80 min after paroxetine caused an additional transient increase in 5-ht levels (to 398+/-52% of baseline). |
2010-07-30 |
2023-08-12 |
rat |
| Cecilie Löe Licht, Gitte Moos Knudsen, Trevor Shar. Effects of the 5-HT(4) receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels. Neuroscience letters. vol 476. issue 2. 2010-07-30. PMID:20381585. |
in conclusion, the 5-ht(4) receptor agonist rs67333 augmented the acute effect of paroxetine on extracellular 5-ht levels in the ventral hippocampus, and after 3 days increased basal hippocampal 5-ht levels. |
2010-07-30 |
2023-08-12 |
rat |
| T Takeuchi, T Owa, T Nishino, C Kame. Assessing anxiolytic-like effects of selective serotonin reuptake inhibitors and serotonin-noradrenaline reuptake inhibitors using the elevated plus maze in mice. Methods and findings in experimental and clinical pharmacology. vol 32. issue 2. 2010-07-26. PMID:20401348. |
the anxiolytic-like effects of selective serotonin reuptake inhibitors (ssris; paroxetine, fluvoxamine) and serotonin-noradrenaline reuptake inhibitors (snris; milnacipran, venlafaxine) were compared with those of benzodiazepines (diazepam, chlordiazepoxide) and tricyclic antidepressants (imipramine, amitriptyline) using the elevated plus maze in mice. |
2010-07-26 |
2023-08-12 |
mouse |
| Hugo R Arias, Dominik Feuerbach, Katarzyna M Targowska-Duda, Megan Russell, Krzysztof Jozwia. Interaction of selective serotonin reuptake inhibitors with neuronal nicotinic acetylcholine receptors. Biochemistry. vol 49. issue 27. 2010-07-20. PMID:20527991. |
we compared the interaction of fluoxetine and paroxetine, two selective serotonin reuptake inhibitors (ssris), with the human (h) alpha4beta2, alpha3beta4, and alpha7 nicotinic acetylcholine receptors (achrs) in different conformational states, using ca(2+) influx, radioligand binding, and molecular docking approaches. |
2010-07-20 |
2023-08-12 |
human |
| Naoki Oishi, Sho Kanzaki, Seiichi Shinden, Hideyuki Saito, Yasuhiro Inoue, Kaoru Ogaw. Effects of selective serotonin reuptake inhibitor on treating tinnitus in patients stratified for presence of depression or anxiety. Audiology & neuro-otology. vol 15. issue 3. 2010-07-07. PMID:19851065. |
we evaluated the effects of a selective serotonin reuptake inhibitor, paroxetine, on treating tinnitus.tinnitus patients stratified for the presence of depression and anxiety were studied retrospectively. |
2010-07-07 |
2023-08-12 |
Not clear |
| Eva L van Donkelaar, Paul A T Kelly, Neil Dawson, Arjan Blokland, Jos Prickaerts, Harry W M Steinbusch, Linda Ferringto. Acute tryptophan depletion potentiates 3,4-methylenedioxymethamphetamine-induced cerebrovascular hyperperfusion in adult male Wistar rats. Journal of neuroscience research. vol 88. issue 7. 2010-06-30. PMID:19998482. |
a significant reduction in paroxetine binding to 5-ht transporter sites in mdma-treated rats indicated 5ht terminal depletion, whereas the plasma trp/sum large neutral amino acids ratio was reduced by 40% following atd. |
2010-06-30 |
2023-08-12 |
rat |