| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christina L M Jobson, Justine Renard, Hanna Szkudlarek, Laura G Rosen, Brian Pereira, Daniel J Wright, Walter Rushlow, Steven R Laviolett. Adolescent Nicotine Exposure Induces Dysregulation of Mesocorticolimbic Activity States and Depressive and Anxiety-like Prefrontal Cortical Molecular Phenotypes Persisting into Adulthood. Cerebral cortex (New York, N.Y. : 1991). vol 29. issue 7. 2020-09-28. PMID:30124787. |
disturbances in the mesocorticolimbic dopamine (da) system, comprising the prefrontal cortex (pfc), ventral tegmental area (vta), and nucleus accumbens (nac), are correlates of mood and anxiety-related symptoms and this circuitry is strongly influenced by acute or chronic nicotine exposure. |
2020-09-28 |
2023-08-13 |
rat |
| Jennifer B Dwyer, Anjelica Cardenas, Ryan M Franke, YiLing Chen, Yu Bai, James D Belluzzi, Shahrdad Lotfipour, Frances M Lesli. Prenatal nicotine sex-dependently alters adolescent dopamine system development. Translational psychiatry. vol 9. issue 1. 2020-09-21. PMID:31740669. |
we presently show, however, that sustained exposure to low doses of nicotine during fetal development, approximating plasma levels seen clinically with the nicotine patch, produces substantial changes in developing corticostriatal dopamine systems in adolescence. |
2020-09-21 |
2023-08-13 |
Not clear |
| Robert A Waeiss, Christopher P Knight, Gustavo B Carvajal, Richard L Bell, Eric A Engleman, William J McBride, Sheketha R Hauser, Zachary A Rod. Peri-adolescent alcohol consumption increases sensitivity and dopaminergic response to nicotine during adulthood in female alcohol-preferring (P) rats: Alterations to α7 nicotinic acetylcholine receptor expression. Behavioural brain research. vol 376. 2020-09-17. PMID:31473285. |
nicotine microinjected directly into the posterior ventral tegmental area (pvta) stimulates dopamine (da) release in the nucleus accumbens (nac) shell. |
2020-09-17 |
2023-08-13 |
human |
| Alexis E Whitton, Alan I Green, Diego A Pizzagalli, Robert M Roth, Jill M Williams, Mary F Brunett. Potent Dopamine D2 Antagonists Block the Reward-Enhancing Effects of Nicotine in Smokers With Schizophrenia. Schizophrenia bulletin. vol 45. issue 6. 2020-09-16. PMID:30690638. |
potent dopamine d2 antagonists block the reward-enhancing effects of nicotine in smokers with schizophrenia. |
2020-09-16 |
2023-08-13 |
human |
| Alexis E Whitton, Alan I Green, Diego A Pizzagalli, Robert M Roth, Jill M Williams, Mary F Brunett. Potent Dopamine D2 Antagonists Block the Reward-Enhancing Effects of Nicotine in Smokers With Schizophrenia. Schizophrenia bulletin. vol 45. issue 6. 2020-09-16. PMID:30690638. |
antipsychotics that are potent dopamine (da) d2 receptor antagonists have been linked to elevated levels of nicotine dependence in smokers with schizophrenia. |
2020-09-16 |
2023-08-13 |
human |
| Travis E Baker, Yashar Zeighami, Alain Dagher, Clay B Holroy. Smoking Decisions: Altered Reinforcement Learning Signals Induced by Nicotine State. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 22. issue 2. 2020-08-25. PMID:29982681. |
alterations in dopamine signaling play a key role in reinforcement learning and nicotine addiction, but the relationship between these two processes has not been well characterized. |
2020-08-25 |
2023-08-13 |
Not clear |
| Renee F Keller, Tina Kazemi, Andrei Dragomir, Yasemin M Akay, Metin Aka. Comparison between dopaminergic and non-dopaminergic neurons in the VTA following chronic nicotine exposure during pregnancy. Scientific reports. vol 9. issue 1. 2020-07-27. PMID:30679632. |
several studies have shown that nicotine produces long-lasting effects on gene expression within many brain regions, including the ventral tegmental area (vta), which is the origin of dopaminergic neurons and the dopamine reward pathway. |
2020-07-27 |
2023-08-13 |
rat |
| Jordan M Buck, Heidi C O'Neill, Jerry A Stitze. Developmental nicotine exposure elicits multigenerational disequilibria in proBDNF proteolysis and glucocorticoid signaling in the frontal cortices, striata, and hippocampi of adolescent mice. Biochemical pharmacology. vol 168. 2020-07-06. PMID:31404529. |
modeling the multigenerational effects of smoking during pregnancy and nursing in the first- (f1) and second- (f2) generation adolescent offspring of oral nicotine-treated female c57bl/6j mice, we have previously reported that dne precipitates intergenerational transmission of nicotine preference, hyperactivity and impulsivity-like behaviors, altered rhythmicity of home cage activity, corticostriatal nicotinic acetylcholine receptor and dopamine transporter dysfunction, and corticostriatal global dna methylome deficits. |
2020-07-06 |
2023-08-13 |
mouse |
| Mohammad-Reza Zarrindast, Fatemeh Khakpa. The modulatory role of nicotine on cognitive and non-cognitive functions. Brain research. vol 1710. 2020-06-25. PMID:30529105. |
furthermore, the effect of nicotine in modulation of cognitive and non-cognitive functions can produce by other neurochemical systems such as opioid, dopamine, glutamate, cannabinoids, gaba and serotonin as well as nitric oxide. |
2020-06-25 |
2023-08-13 |
Not clear |
| András Buzás, Péter Bokor, Beáta Balangó, Dávid Pintér, Miklós Palotai, Balázs Simon, Krisztina Csabafi, Gyula Telegdy, Gyula Szabó, Zsolt Bagos. Changes in striatal dopamine release and locomotor activity following acute withdrawal from chronic nicotine are mediated by CRF1, but not CRF2, receptors. Brain research. vol 1706. 2020-05-29. PMID:30722977. |
changes in striatal dopamine release and locomotor activity following acute withdrawal from chronic nicotine are mediated by crf1, but not crf2, receptors. |
2020-05-29 |
2023-08-13 |
rat |
| András Buzás, Péter Bokor, Beáta Balangó, Dávid Pintér, Miklós Palotai, Balázs Simon, Krisztina Csabafi, Gyula Telegdy, Gyula Szabó, Zsolt Bagos. Changes in striatal dopamine release and locomotor activity following acute withdrawal from chronic nicotine are mediated by CRF1, but not CRF2, receptors. Brain research. vol 1706. 2020-05-29. PMID:30722977. |
the aim of the present study was to investigate the participation of corticotropin-releasing factor (crf) receptors (crf1 and crf2) in the alterations of the dorsal and ventral striatal dopamine release and the vertical and horizontal locomotor activity observed in rats following chronic nicotine treatment and consequent acute withdrawal. |
2020-05-29 |
2023-08-13 |
rat |
| Yuan-Hao Chen, Bon-Jour Lin, Tsung-Hsun Hsieh, Tung-Tai Kuo, Jonathan Miller, Yu-Ching Chou, Eagle Yi-Kung Huang, Barry J Hoffe. Differences in Nicotine Encoding Dopamine Release between the Striatum and Shell Portion of the Nucleus Accumbens. Cell transplantation. vol 28. issue 3. 2020-04-30. PMID:29807460. |
differences in nicotine encoding dopamine release between the striatum and shell portion of the nucleus accumbens. |
2020-04-30 |
2023-08-13 |
rat |
| Yuan-Hao Chen, Bon-Jour Lin, Tsung-Hsun Hsieh, Tung-Tai Kuo, Jonathan Miller, Yu-Ching Chou, Eagle Yi-Kung Huang, Barry J Hoffe. Differences in Nicotine Encoding Dopamine Release between the Striatum and Shell Portion of the Nucleus Accumbens. Cell transplantation. vol 28. issue 3. 2020-04-30. PMID:29807460. |
the aim of this work was to determine the effect of nicotine desensitization on dopamine (da) release in the dorsal striatum and shell of the nucleus accumbens (nac) from brain slices. |
2020-04-30 |
2023-08-13 |
rat |
| Yuan-Hao Chen, Bon-Jour Lin, Tsung-Hsun Hsieh, Tung-Tai Kuo, Jonathan Miller, Yu-Ching Chou, Eagle Yi-Kung Huang, Barry J Hoffe. Differences in Nicotine Encoding Dopamine Release between the Striatum and Shell Portion of the Nucleus Accumbens. Cell transplantation. vol 28. issue 3. 2020-04-30. PMID:29807460. |
in vitro fast-scan cyclic voltammetry analysis was used to evaluate dopamine release in the dorsal striatum and the nac shell of sprague-dawley rats after infusion of nicotine, a nicotinic acetylcholine receptor (nachr) antagonist mecamylamine (mec), and an α4β2 cholinergic receptor antagonist (dhβe). |
2020-04-30 |
2023-08-13 |
rat |
| Taryn E Grieder, Morgane Besson, Geith Maal-Bared, Stéphanie Pons, Uwe Maskos, Derek van der Koo. β2* nAChRs on VTA dopamine and GABA neurons separately mediate nicotine aversion and reward. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 51. 2020-04-01. PMID:31776253. |
β2* nachrs on vta dopamine and gaba neurons separately mediate nicotine aversion and reward. |
2020-04-01 |
2023-08-13 |
Not clear |
| Taryn E Grieder, Morgane Besson, Geith Maal-Bared, Stéphanie Pons, Uwe Maskos, Derek van der Koo. β2* nAChRs on VTA dopamine and GABA neurons separately mediate nicotine aversion and reward. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 51. 2020-04-01. PMID:31776253. |
evidence shows that the neurotransmitter dopamine mediates the rewarding effects of nicotine and other drugs of abuse, while nondopaminergic neural substrates mediate the negative motivational effects. |
2020-04-01 |
2023-08-13 |
Not clear |
| Federica Bono, Veronica Mutti, Paola Savoia, Alessandro Barbon, Arianna Bellucci, Cristina Missale, Chiara Fiorentin. Nicotine prevents alpha-synuclein accumulation in mouse and human iPSC-derived dopaminergic neurons through activation of the dopamine D3- acetylcholine nicotinic receptor heteromer. Neurobiology of disease. vol 129. 2020-03-24. PMID:31051233. |
nicotine prevents alpha-synuclein accumulation in mouse and human ipsc-derived dopaminergic neurons through activation of the dopamine d3- acetylcholine nicotinic receptor heteromer. |
2020-03-24 |
2023-08-13 |
mouse |
| Federica Bono, Veronica Mutti, Paola Savoia, Alessandro Barbon, Arianna Bellucci, Cristina Missale, Chiara Fiorentin. Nicotine prevents alpha-synuclein accumulation in mouse and human iPSC-derived dopaminergic neurons through activation of the dopamine D3- acetylcholine nicotinic receptor heteromer. Neurobiology of disease. vol 129. 2020-03-24. PMID:31051233. |
we recently found that in mouse dopaminergic neurons, the heteromer formed by the dopamine d3 receptor (d3r) and the β2 subunit of acetylcholine nicotinic receptor (nachr) exerts neurotrophic effects when activated by nicotine, leading to neurons with enlarged cell bodies and increased dendrite arborization. |
2020-03-24 |
2023-08-13 |
mouse |
| Devon DiPalma, Amir H Rezvani, Blair Willette, Corinne Wells, Susan Slade, Brandon J Hall, Edward D Levi. Persistent attenuation of nicotine self-administration in rats by co-administration of chronic nicotine infusion with the dopamine D Pharmacology, biochemistry, and behavior. vol 176. 2020-02-25. PMID:30419272. |
persistent attenuation of nicotine self-administration in rats by co-administration of chronic nicotine infusion with the dopamine d tobacco addiction each year causes millions of deaths worldwide. |
2020-02-25 |
2023-08-13 |
rat |
| Devon DiPalma, Amir H Rezvani, Blair Willette, Corinne Wells, Susan Slade, Brandon J Hall, Edward D Levi. Persistent attenuation of nicotine self-administration in rats by co-administration of chronic nicotine infusion with the dopamine D Pharmacology, biochemistry, and behavior. vol 176. 2020-02-25. PMID:30419272. |
nicotine increases the release of a variety of neurotransmitters, including dopamine and serotonin. |
2020-02-25 |
2023-08-13 |
rat |