| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Russell W Brown, Marjorie A Schlitt, Alex S Owens, Caitlynn C DePreter, Elizabeth D Cummins, Seth L Kirby, W Drew Gill, Katherine C Burges. Effects of Environmental Enrichment on Nicotine Sensitization in Rats Neonatally Treated with Quinpirole: Analyses of Glial Cell Line-Derived Neurotrophic Factor and Implications towards Schizophrenia. Developmental neuroscience. vol 40. issue 1. 2018-10-16. PMID:29444518. |
the current study analyzed the effects of environmental enrichment versus isolation housing on the behavioral sensitization to nicotine in the neonatal quinpirole (nq; dopamine d2-like agonist) model of dopamine d2 receptor supersensitivity, a rodent model of schizophrenia. |
2018-10-16 |
2023-08-13 |
rat |
| Marta Napierała, Joanna Bogusiewicz, Jolanta Enko, Ewa Flore. [Nicotine and caffeine: influence on dopaminergic transmission]. Przeglad lekarski. vol 73. issue 10. 2018-09-07. PMID:29689686. |
disorders of the productionand release of dopamine can bethe base of the pathomechanism ofmany diseases.both nicotine and caffeine arepsychomotor stimulants. |
2018-09-07 |
2023-08-13 |
Not clear |
| Ana C Dutra-Tavares, Juliana O Silva, André L Nunes-Freitas, Vinícius M S Guimarães, Ulisses C Araújo, Ellen P S Conceição, Egberto G Moura, Patrícia C Lisboa, Cláudio C Filgueiras, Alex C Manhães, Yael Abreu-Villaça, Anderson Ribeiro-Carvalh. Maternal undernutrition during lactation alters nicotine reward and DOPAC/dopamine ratio in cerebral cortex in adolescent mice, but does not affect nicotine-induced nAChRs upregulation. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 65. 2018-09-05. PMID:29054611. |
the goal of this study was to investigate the effects of undernutrition during lactation on the nicotine susceptibility indexed via conditioned place preference (cpp), on dopamine content and turnover and on nicotine-induced nicotinic cholinergic receptor (nachr) upregulation in the cerebral cortex, midbrain and hippocampus of adolescent mice. |
2018-09-05 |
2023-08-13 |
mouse |
| Jose I Juncosa, Kenji Takaya, Hoang V Le, Matthew J Moschitto, Pathum M Weerawarna, Romila Mascarenhas, Dali Liu, Stephen L Dewey, Richard B Silverma. Design and Mechanism of (S)-3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ-Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction. Journal of the American Chemical Society. vol 140. issue 6. 2018-07-17. PMID:29381352. |
in vivo studies in freely moving rats showed that 5 was dramatically superior to cpp-115 in suppressing the release of dopamine in the corpus striatum, which occurs subsequent to either an acute cocaine or nicotine challenge. |
2018-07-17 |
2023-08-13 |
rat |
| Dolores B Vazquez-Sanroman, Reyna D Monje, Michael T Bard. Nicotine self-administration remodels perineuronal nets in ventral tegmental area and orbitofrontal cortex in adult male rats. Addiction biology. vol 22. issue 6. 2018-07-16. PMID:27549591. |
nicotine, a major psychoactive component of tobacco smoke, alters gamma-aminobutyric acid (gaba) modulation of dopamine neurons in the ventral tegmental area (vta). |
2018-07-16 |
2023-08-13 |
rat |
| Robert J Wickham, Eric J Nunes, Shannon Hughley, Phillip Silva, Sofia N Walton, Jinwoo Park, Nii A Add. Evaluating oral flavorant effects on nicotine self-administration behavior and phasic dopamine signaling. Neuropharmacology. vol 128. 2018-07-13. PMID:28943284. |
evaluating oral flavorant effects on nicotine self-administration behavior and phasic dopamine signaling. |
2018-07-13 |
2023-08-13 |
rat |
| Robert J Wickham, Eric J Nunes, Shannon Hughley, Phillip Silva, Sofia N Walton, Jinwoo Park, Nii A Add. Evaluating oral flavorant effects on nicotine self-administration behavior and phasic dopamine signaling. Neuropharmacology. vol 128. 2018-07-13. PMID:28943284. |
nicotine self-administration in adult, male rats, we examined whether flavors alter phasic dopamine (da) signaling and nicotine self-administration. |
2018-07-13 |
2023-08-13 |
rat |
| Eileen N Oni, Apoorva Halikere, Guohui Li, Alana J Toro-Ramos, Mavis R Swerdel, Jessica L Verpeut, Jennifer C Moore, Nicholas T Bello, Laura J Bierut, Alison Goate, Jay A Tischfield, Zhiping P Pang, Ronald P Har. Increased nicotine response in iPSC-derived human neurons carrying the CHRNA5 N398 allele. Scientific reports. vol 6. 2018-07-10. PMID:27698409. |
to understand the impact of these nicotinic receptor variants in humans, we differentiated these ipscs to dopamine (da) or glutamatergic neurons and then tested their functional properties and response to nicotine. |
2018-07-10 |
2023-08-13 |
human |
| Cody A Siciliano, J Michael McIntosh, Sara R Jones, Mark J Ferri. α6β2 subunit containing nicotinic acetylcholine receptors exert opposing actions on rapid dopamine signaling in the nucleus accumbens of rats with high-versus low-response to novelty. Neuropharmacology. vol 126. 2018-06-12. PMID:28666811. |
using voltammetry in the nucleus accumbens core of rats, we found that nicotine produced opposite effects in hr and lr animals on stimulation frequencies that model phasic dopamine release, whereby release magnitude was either augmented or attenuated, respectively. |
2018-06-12 |
2023-08-13 |
rat |
| Cody A Siciliano, J Michael McIntosh, Sara R Jones, Mark J Ferri. α6β2 subunit containing nicotinic acetylcholine receptors exert opposing actions on rapid dopamine signaling in the nucleus accumbens of rats with high-versus low-response to novelty. Neuropharmacology. vol 126. 2018-06-12. PMID:28666811. |
further, nicotine suppressed dopamine release elected by stimulation frequencies that model tonic release in lr animals, but had no effect in hr animals. |
2018-06-12 |
2023-08-13 |
rat |
| Jianxun Xia, Allison M Meyers, Jeff A Beele. Chronic Nicotine Alters Corticostriatal Plasticity in the Striatopallidal Pathway Mediated By NR2B-Containing Silent Synapses. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 12. 2018-06-04. PMID:28462940. |
we used whole-cell patch clamp recording to investigate the effect of chronic nicotine (cnic) on synaptic plasticity in dopamine d2 receptor-expressing medium-spiny neurons in the indirect, striatopallidal pathway in dorsolateral striatum. |
2018-06-04 |
2023-08-13 |
mouse |
| Julie A Marusich, Mahesh Darna, A George Wilson, Emily D Denehy, Amanda Ebben, Agripina G Deaciuc, Linda P Dwoskin, Michael T Bardo, Timothy W Lefever, Jenny L Wiley, Chad J Reissig, Kia J Jackso. Tobacco's minor alkaloids: Effects on place conditioning and nucleus accumbens dopamine release in adult and adolescent rats. European journal of pharmacology. vol 814. 2018-06-01. PMID:28844873. |
nicotine increased dopamine release at both ages, and anatabine and myosmine increased dopamine release in adults, but not adolescents. |
2018-06-01 |
2023-08-13 |
rat |
| Julie A Marusich, Mahesh Darna, A George Wilson, Emily D Denehy, Amanda Ebben, Agripina G Deaciuc, Linda P Dwoskin, Michael T Bardo, Timothy W Lefever, Jenny L Wiley, Chad J Reissig, Kia J Jackso. Tobacco's minor alkaloids: Effects on place conditioning and nucleus accumbens dopamine release in adult and adolescent rats. European journal of pharmacology. vol 814. 2018-06-01. PMID:28844873. |
the dopamine release results were not related to place conditioning, as nicotine and cotinine had no effect on place conditioning, whereas anatabine and myosmine produced aversion in both ages. |
2018-06-01 |
2023-08-13 |
rat |
| Marcela Waisman Campos, Debora Serebrisky, Joao Mauricio Castaldelli-Mai. Smoking and Cognition. Current drug abuse reviews. vol 9. issue 2. 2018-05-28. PMID:27492358. |
given the large availability of nicotinic acetylcholine receptors (nachrs) throughout the brain, and the wide range of neurotransmitter systems affected (norepinephrine, serotonin and dopamine), nicotine influences a wide variety of cognitive domains such as sensorial, motor, attention, executive function, learning and memory. |
2018-05-28 |
2023-08-13 |
Not clear |
| Amy R Dunn, Kristen A Stout, Minagi Ozawa, Kelly M Lohr, Carlie A Hoffman, Alison I Bernstein, Yingjie Li, Minzheng Wang, Carmelo Sgobio, Namratha Sastry, Huaibin Cai, W Michael Caudle, Gary W Mille. Synaptic vesicle glycoprotein 2C (SV2C) modulates dopamine release and is disrupted in Parkinson disease. Proceedings of the National Academy of Sciences of the United States of America. vol 114. issue 11. 2018-04-23. PMID:28246328. |
genetic deletion of sv2c leads to reduced dopamine release in the dorsal striatum as measured by fast-scan cyclic voltammetry, reduced striatal dopamine content, disrupted α-synuclein expression, deficits in motor function, and alterations in neurochemical effects of nicotine. |
2018-04-23 |
2023-08-13 |
mouse |
| Jennifer E Naylor, Takato Hiranita, Katelin S Matazel, Xuan Zhang, Merle G Paule, Amy K Goodwi. Positron emission tomography (PET) imaging of nicotine-induced dopamine release in squirrel monkeys using [ Drug and alcohol dependence. vol 179. 2018-04-17. PMID:28818716. |
positron emission tomography (pet) imaging of nicotine-induced dopamine release in squirrel monkeys using [ nicotine, the principal psychoactive tobacco constituent, is thought to produce its reinforcing effects via actions within the mesolimbic dopamine (da) system. |
2018-04-17 |
2023-08-13 |
monkey |
| Daniel G Ehlinger, Julian C Burke, Craig G McDonald, Robert F Smith, Hadley C Bergstro. Nicotine-induced and D1-receptor-dependent dendritic remodeling in a subset of dorsolateral striatum medium spiny neurons. Neuroscience. vol 356. 2018-04-12. PMID:28576726. |
co-administration of the dopamine d1 receptor (d1r) antagonist sch23390 completely reversed the selective effects of nicotine on dls msn dendrite morphology, supporting a causal role for dopamine signaling at d1 receptors in nicotine-induced dendrite restructuring. |
2018-04-12 |
2023-08-13 |
rat |
| Taryn E Grieder, Olivier George, Mandy Yee, Michael A Bergamini, Michal Chwalek, Geith Maal-Bared, Hector Vargas-Perez, Derek van der Koo. Deletion of α5 nicotine receptor subunits abolishes nicotinic aversive motivational effects in a manner that phenocopies dopamine receptor antagonism. The European journal of neuroscience. vol 46. issue 1. 2018-03-26. PMID:28498560. |
these effects phenocopy those observed after dopamine receptor antagonism, but are not additive, suggesting that α5 nachr subunits act in the same pathway as dopamine and are critical for the experience of nicotine's aversive, but not rewarding motivational effects in both a nondependent and nicotine-dependent and -withdrawn motivational state. |
2018-03-26 |
2023-08-13 |
mouse |
| Maria E Secci, Alessia Auber, Leigh V Panlilio, Godfrey H Redhi, Eric B Thorndike, Charles W Schindler, Robert Schwarcz, Steven R Goldberg, Zuzana Justinov. Attenuating Nicotine Reinforcement and Relapse by Enhancing Endogenous Brain Levels of Kynurenic Acid in Rats and Squirrel Monkeys. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 42. issue 8. 2018-03-23. PMID:28139681. |
in rats, ro 61-8048 reduced the ability of nicotine to induce dopamine release in the nucleus accumbens shell, a brain area believed to underlie nicotine reward. |
2018-03-23 |
2023-08-13 |
rat |
| Annabeth P Groenman, Corina U Greven, Marjolein M J van Donkelaar, Arnt Schellekens, Kimm J E van Hulzen, Nanda Rommelse, Catharina A Hartman, Pieter J Hoekstra, Marjolein Luman, Barbara Franke, Stephen V Faraone, Jaap Oosterlaan, Jan K Buitelaa. Dopamine and serotonin genetic risk scores predicting substance and nicotine use in attention deficit/hyperactivity disorder. Addiction biology. vol 21. issue 4. 2018-01-29. PMID:25752199. |
dopamine and serotonin genetic risk scores predicting substance and nicotine use in attention deficit/hyperactivity disorder. |
2018-01-29 |
2023-08-13 |
human |