| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W Goutier, J P Lowry, A C McCreary, J J O'Conno. Frequency-Dependent Modulation of Dopamine Release by Nicotine and Dopamine D1 Receptor Ligands: An In Vitro Fast Cyclic Voltammetry Study in Rat Striatum. Neurochemical research. vol 41. issue 5. 2016-12-13. PMID:26975318. |
in this study we have demonstrated that the modulation of dopamine release by nicotine can be altered by d1r ligands, but only when evoked by single pulse stimulation, and are likely working via cholinergic interneuron driven dopamine release. |
2016-12-13 |
2023-08-13 |
rat |
| Philip A Adeniyi, Azeez O Ishola, Babafemi J Laoye, Babawale P Olatunji, Oluwamolakun O Bankole, Philemon D Shallie, Olalekan M Ogundel. Neural and behavioural changes in male periadolescent mice after prolonged nicotine-MDMA treatment. Metabolic brain disease. vol 31. issue 1. 2016-10-17. PMID:26088184. |
the interaction between mdma and nicotine affects multiple brain centres and neurotransmitter systems (serotonin, dopamine and glutamate) involved in motor coordination and cognition. |
2016-10-17 |
2023-08-13 |
mouse |
| Li Wen, Keran Jiang, Wenji Yuan, Wenyan Cui, Ming D L. Contribution of Variants in CHRNA5/A3/B4 Gene Cluster on Chromosome 15 to Tobacco Smoking: From Genetic Association to Mechanism. Molecular neurobiology. vol 53. issue 1. 2016-10-07. PMID:25471942. |
nicotine exerts its physiological and pharmacological roles in the brain through neuronal nicotinic acetylcholine receptors (nachrs), which are ligand-gated ion channels consisting of five membrane-spanning subunits that can modulate the release of neurotransmitters, such as dopamine, glutamate, and gaba and mediate fast signal transmission at synapses. |
2016-10-07 |
2023-08-13 |
Not clear |
| Hye Duck Choi, Wan Gyoon Shi. Association between catechol-O-methyltransferase (COMT) Val/Met genotype and smoking cessation treatment with nicotine: a meta-analysis. Pharmacogenomics. vol 16. issue 16. 2016-09-12. PMID:26555332. |
catechol-o-methyltransferase (comt) is one of the major degradative pathways of dopamine and comt val/met polymorphisms are associated with the enzyme activity, which is related to dopamine involvement in the nicotine addiction process. |
2016-09-12 |
2023-08-13 |
Not clear |
| Joshua S Beckmann, Andrew C Meyer, M Pivavarchyk, David B Horton, Guangrong Zheng, Andrew M Smith, Thomas E Wooters, J Michael McIntosh, Peter A Crooks, Michael T Bardo, Linda P Dwoski. r-bPiDI, an α6β2* Nicotinic Receptor Antagonist, Decreases Nicotine-Evoked Dopamine Release and Nicotine Reinforcement. Neurochemical research. vol 40. issue 10. 2016-09-02. PMID:26227997. |
r-bpidi, an α6β2* nicotinic receptor antagonist, decreases nicotine-evoked dopamine release and nicotine reinforcement. |
2016-09-02 |
2023-08-13 |
rat |
| Joshua S Beckmann, Andrew C Meyer, M Pivavarchyk, David B Horton, Guangrong Zheng, Andrew M Smith, Thomas E Wooters, J Michael McIntosh, Peter A Crooks, Michael T Bardo, Linda P Dwoski. r-bPiDI, an α6β2* Nicotinic Receptor Antagonist, Decreases Nicotine-Evoked Dopamine Release and Nicotine Reinforcement. Neurochemical research. vol 40. issue 10. 2016-09-02. PMID:26227997. |
α6β2* nicotinic acetylcholine receptors (nachrs) expressed by dopaminergic neurons mediate nicotine-evoked dopamine (da) release and nicotine reinforcement. |
2016-09-02 |
2023-08-13 |
rat |
| Brandon J Hall, Susan Slade, Cheyenne Allenby, Munir G Kutlu, Edward D Levi. Neuro-anatomic mapping of dopamine D1 receptor involvement in nicotine self-administration in rats. Neuropharmacology. vol 99. 2016-08-30. PMID:25797492. |
neuro-anatomic mapping of dopamine d1 receptor involvement in nicotine self-administration in rats. |
2016-08-30 |
2023-08-13 |
rat |
| H E AlQot, N A Elnozahi, M M Mohy El-Din, A E Bistawroos, M S Abou Zeit-Ha. Facilitatory effect of dopamine on neuromuscular transmission mediated via dopamine D1-like receptors and prospective interaction with nicotine. European journal of pharmacology. vol 765. 2016-08-01. PMID:26277323. |
facilitatory effect of dopamine on neuromuscular transmission mediated via dopamine d1-like receptors and prospective interaction with nicotine. |
2016-08-01 |
2023-08-13 |
rat |
| H E AlQot, N A Elnozahi, M M Mohy El-Din, A E Bistawroos, M S Abou Zeit-Ha. Facilitatory effect of dopamine on neuromuscular transmission mediated via dopamine D1-like receptors and prospective interaction with nicotine. European journal of pharmacology. vol 765. 2016-08-01. PMID:26277323. |
the objective of this study is to probe the effects of dopamine and potential interactions with nicotine at the motor end plate. |
2016-08-01 |
2023-08-13 |
rat |
| H E AlQot, N A Elnozahi, M M Mohy El-Din, A E Bistawroos, M S Abou Zeit-Ha. Facilitatory effect of dopamine on neuromuscular transmission mediated via dopamine D1-like receptors and prospective interaction with nicotine. European journal of pharmacology. vol 765. 2016-08-01. PMID:26277323. |
the facilitatory effect of dopamine was potentiated in nicotine treated rats. |
2016-08-01 |
2023-08-13 |
rat |
| H E AlQot, N A Elnozahi, M M Mohy El-Din, A E Bistawroos, M S Abou Zeit-Ha. Facilitatory effect of dopamine on neuromuscular transmission mediated via dopamine D1-like receptors and prospective interaction with nicotine. European journal of pharmacology. vol 765. 2016-08-01. PMID:26277323. |
in addition, it highlighted the possible dependency of dopamine effects on intracellular calcium and signified potential interaction among dopamine and nicotine. |
2016-08-01 |
2023-08-13 |
rat |
| Kate Cahill, Nicola Lindson-Hawley, Kyla H Thomas, Thomas R Fanshawe, Tim Lancaste. Nicotine receptor partial agonists for smoking cessation. The Cochrane database of systematic reviews. issue 5. 2016-07-28. PMID:27158893. |
nicotine receptor partial agonists may help people to stop smoking by a combination of maintaining moderate levels of dopamine to counteract withdrawal symptoms (acting as an agonist) and reducing smoking satisfaction (acting as an antagonist). |
2016-07-28 |
2023-08-13 |
Not clear |
| Edward D Levin, Corinne Wells, Joshua E Johnson, Amir H Rezvani, Frank P Bymaster, Jed E Ros. Amitifadine, a triple monoamine re-uptake inhibitor, reduces nicotine self-administration in female rats. European journal of pharmacology. vol 764. 2016-07-21. PMID:26101069. |
this study was conducted to determine whether amitifadine, which inhibits re-uptake of dopamine, norepinephrine and serotonin, would decrease nicotine self-administration at doses that do not cause adverse side effects. |
2016-07-21 |
2023-08-13 |
rat |
| Jin H Yoon, Scott D Lane, Michael F Weave. Opioid Analgesics and Nicotine: More Than Blowing Smoke. Journal of pain & palliative care pharmacotherapy. vol 29. issue 3. 2016-07-20. PMID:26375198. |
opioid and nicotinic-cholinergic neurotransmitter systems interact in important ways to modulate opioid and nicotine effects: dopamine release induced by nicotine is dependent on facilitation by the opioid system, and the nicotinic-acetylcholine system modulates self-administration of several classes of abused drugs-including opioids. |
2016-07-20 |
2023-08-13 |
Not clear |
| Brandon J Henderson, Teagan R Wall, Beverley M Henley, Charlene H Kim, Weston A Nichols, Ruin Moaddel, Cheng Xiao, Henry A Leste. Menthol Alone Upregulates Midbrain nAChRs, Alters nAChR Subtype Stoichiometry, Alters Dopamine Neuron Firing Frequency, and Prevents Nicotine Reward. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 10. 2016-07-19. PMID:26961950. |
menthol alone upregulates midbrain nachrs, alters nachr subtype stoichiometry, alters dopamine neuron firing frequency, and prevents nicotine reward. |
2016-07-19 |
2023-08-13 |
mouse |
| Matthew W Buczynski, Melissa A Herman, Ku-Lung Hsu, Luis A Natividad, Cristina Irimia, Ilham Y Polis, Holly Pugh, Jae Won Chang, Micah J Niphakis, Benjamin F Cravatt, Marisa Roberto, Loren H Parson. Diacylglycerol lipase disinhibits VTA dopamine neurons during chronic nicotine exposure. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 4. 2016-06-17. PMID:26755579. |
diacylglycerol lipase disinhibits vta dopamine neurons during chronic nicotine exposure. |
2016-06-17 |
2023-08-13 |
rat |
| Pamela Sabioni, Patricia Di Ciano, Bernard Le Fol. Effect of a D3 receptor antagonist on context-induced reinstatement of nicotine seeking. Progress in neuro-psychopharmacology & biological psychiatry. vol 64. 2016-05-31. PMID:26279138. |
we and others have proposed that targeting the dopamine d3 receptor (drd3) may be a good strategy for treatment of nicotine dependence. |
2016-05-31 |
2023-08-13 |
human |
| Aruna Prasopthum, Phisit Pouyfung, Songklod Sarapusit, Ekaruth Srisook, Pornpimol Rongnoparu. Inhibition effects of Vernonia cinerea active compounds against cytochrome P450 2A6 and human monoamine oxidases, possible targets for reduction of tobacco dependence. Drug metabolism and pharmacokinetics. vol 30. issue 2. 2016-05-23. PMID:25857233. |
the human cytochrome p450 2a6 (cyp2a6) and monoamine oxidases (mao-a and mao-b), catalyzing nicotine and dopamine metabolisms, respectively, are two therapeutic targets of nicotine dependence. |
2016-05-23 |
2023-08-13 |
human |
| C R Pinheiro, E Oliveira, A C Manhães, M C Fraga, S Claudio-Neto, V Younes-Rapozo, B M Lotufo, E G Moura, P C Lisbo. Exposure to nicotine increases dopamine receptor content in the mesocorticolimbic pathway of rat dams and offspring during lactation. Pharmacology, biochemistry, and behavior. vol 136. 2016-05-17. PMID:26219213. |
nicotine exposure causes the release of dopamine from the ventral tegmental area (vta) to the nucleus accumbens (nac). |
2016-05-17 |
2023-08-13 |
rat |
| C R Pinheiro, E Oliveira, A C Manhães, M C Fraga, S Claudio-Neto, V Younes-Rapozo, B M Lotufo, E G Moura, P C Lisbo. Exposure to nicotine increases dopamine receptor content in the mesocorticolimbic pathway of rat dams and offspring during lactation. Pharmacology, biochemistry, and behavior. vol 136. 2016-05-17. PMID:26219213. |
we have previously shown that maternal exposure to nicotine during lactation causes hyperleptinemia in dams and pups, and leptin is known to decrease dopamine release from the vta. |
2016-05-17 |
2023-08-13 |
rat |