| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tursun Alkam, Takayoshi Mamiya, Nami Kimura, Aya Yoshida, Daisuke Kihara, Yuki Tsunoda, Yuki Aoyama, Masayuki Hiramatsu, Hyoung-Chun Kim, Toshitaka Nabeshim. Prenatal nicotine exposure decreases the release of dopamine in the medial frontal cortex and induces atomoxetine-responsive neurobehavioral deficits in mice. Psychopharmacology. vol 234. issue 12. 2018-01-24. PMID:28332006. |
prenatal nicotine exposure decreases the release of dopamine in the medial frontal cortex and induces atomoxetine-responsive neurobehavioral deficits in mice. |
2018-01-24 |
2023-08-13 |
mouse |
| Emma Beard, Lion Shahab, Damian M Cummings, Susan Michie, Robert Wes. New Pharmacological Agents to Aid Smoking Cessation and Tobacco Harm Reduction: What Has Been Investigated, and What Is in the Pipeline? CNS drugs. vol 30. issue 10. 2018-01-17. PMID:27421270. |
st john's wort), silver acetate, nicobrevin, modafinil, venlafaxine, monoamine oxidase inhibitors (maois), opioid antagonists, nicotinic acetylcholine receptor (nachr) antagonists, glucose tablets, selective cannabinoid type 1 receptor antagonists, nicotine vaccines, drugs that affect gamma-aminobutyric acid (gaba) transmission, drugs that affect n-methyl-d-aspartate (nmda) receptors, dopamine agonists (e.g. |
2018-01-17 |
2023-08-13 |
Not clear |
| Kyoji Okita, Mark A Mandelkern, Edythe D Londo. Cigarette Use and Striatal Dopamine D2/3 Receptors: Possible Role in the Link between Smoking and Nicotine Dependence. The international journal of neuropsychopharmacology. vol 19. issue 11. 2018-01-08. PMID:27634830. |
cigarette use and striatal dopamine d2/3 receptors: possible role in the link between smoking and nicotine dependence. |
2018-01-08 |
2023-08-13 |
Not clear |
| Kyoji Okita, Mark A Mandelkern, Edythe D Londo. Cigarette Use and Striatal Dopamine D2/3 Receptors: Possible Role in the Link between Smoking and Nicotine Dependence. The international journal of neuropsychopharmacology. vol 19. issue 11. 2018-01-08. PMID:27634830. |
cigarette smoking induces dopamine release in the striatum, and smoking- or nicotine-induced ventral striatal dopamine release is correlated with nicotine dependence. |
2018-01-08 |
2023-08-13 |
Not clear |
| Kyoji Okita, Mark A Mandelkern, Edythe D Londo. Cigarette Use and Striatal Dopamine D2/3 Receptors: Possible Role in the Link between Smoking and Nicotine Dependence. The international journal of neuropsychopharmacology. vol 19. issue 11. 2018-01-08. PMID:27634830. |
negative correlations of striatal dopamine d2/3 receptor availability with smoking exposure and nicotine dependence, therefore, might be expected but have not been tested. |
2018-01-08 |
2023-08-13 |
Not clear |
| Joseph Kambeitz, Christian la Fougère, Natalie Werner, Oliver Pogarell, Michael Riedel, Peter Falkai, Ulrich Ettinge. Nicotine-dopamine-transporter interactions during reward-based decision making. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 26. issue 6. 2018-01-05. PMID:27112968. |
numerous studies point to a potential role of dopamine and nicotine in decision making but less is known about their interactions. |
2018-01-05 |
2023-08-13 |
human |
| Scott T Barrett, Trevor N Geary, Amy N Steiner, Rick A Bevin. Sex differences and the role of dopamine receptors in the reward-enhancing effects of nicotine and bupropion. Psychopharmacology. vol 234. issue 2. 2017-12-05. PMID:27695921. |
sex differences and the role of dopamine receptors in the reward-enhancing effects of nicotine and bupropion. |
2017-12-05 |
2023-08-13 |
Not clear |
| Branden L Eggan, Sarah E McCallu. 18-Methoxycoronaridine acts in the medial habenula to attenuate behavioral and neurochemical sensitization to nicotine. Behavioural brain research. vol 307. 2017-11-28. PMID:27059333. |
consistent with its effects on behavioral sensitization, intra-mhb treatment with 18-mc completely abolished sensitized dopamine responses in the nucleus accumbens in nicotine sensitized animals. |
2017-11-28 |
2023-08-13 |
Not clear |
| L Hondebrink, A H A Verboven, W S Drega, S Schmeink, M W G D M de Groot, R G D M van Kleef, F M J Wijnolts, A de Groot, J Meulenbelt, R H S Westerin. Neurotoxicity screening of (illicit) drugs using novel methods for analysis of microelectrode array (MEA) recordings. Neurotoxicology. vol 55. 2017-11-17. PMID:27149913. |
neuronal activity is concentration-dependently affected following exposure to six neurotransmitters (glutamate, gaba, serotonin, dopamine, acetylcholine and nicotine). |
2017-11-17 |
2023-08-13 |
Not clear |
| Kristen Criscitelli, Nicole M Aven. The neurobiological and behavioral overlaps of nicotine and food addiction. Preventive medicine. vol 92. 2017-11-16. PMID:27509870. |
indeed, nicotine and highly palatable foods are capable of altering dopamine release within this system, engendering addictive like responses in susceptible individuals. |
2017-11-16 |
2023-08-13 |
human |
| Michelle G Baladi, Shannon M Nielsen, J Michael McIntosh, Glen R Hanson, Annette E Fleckenstei. Prior nicotine self-administration attenuates subsequent dopaminergic deficits of methamphetamine in rats: role of nicotinic acetylcholine receptors. Behavioural pharmacology. vol 27. issue 5. 2017-11-08. PMID:26871405. |
the findings indicate that nicotine self-administration (0.032 mg/kg/infusion for 14 days) per se did not alter α4β2* and α6β2* nachr expression or dopamine transporter (dat) expression and function. |
2017-11-08 |
2023-08-13 |
rat |
| Oguz Gozen, Tanseli Nesil, Lutfiye Kanit, Ersin O Koylu, Sakire Pogu. Nicotinic cholinergic and dopaminergic receptor mRNA expression in male and female rats with high or low preference for nicotine. The American journal of drug and alcohol abuse. vol 42. issue 5. 2017-11-06. PMID:27428758. |
nicotine exerts its central actions through nicotinic acetylcholine receptors (nachrs), which in turn regulate major neurotransmitter systems including dopamine. |
2017-11-06 |
2023-08-13 |
rat |
| Andrei Dragomir, Yasemin M Akay, Die Zhang, Metin Aka. Ventral Tegmental Area Dopamine Neurons Firing Model Reveals Prenatal Nicotine Induced Alterations. IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society. vol 25. issue 9. 2017-10-27. PMID:28114025. |
ventral tegmental area dopamine neurons firing model reveals prenatal nicotine induced alterations. |
2017-10-27 |
2023-08-13 |
rat |
| Alexander Gomez-A, Amanda M Fiorenza, Suelen L Boschen, Adam H Sugi, Danielle Beckman, Sergio T Ferreira, Kendall Lee, Charles D Blaha, Claudio Da Cunh. Diazepam Inhibits Electrically Evoked and Tonic Dopamine Release in the Nucleus Accumbens and Reverses the Effect of Amphetamine. ACS chemical neuroscience. vol 8. issue 2. 2017-10-24. PMID:28038309. |
in addition, our findings challenge the classic view that all drugs of abuse cause dopamine release in the nucleus accumbens and suggest that benzodiazepines could be useful in the treatment of addiction to other drugs that increase the level of dopamine release, such as cocaine, amphetamines, and nicotine. |
2017-10-24 |
2023-08-13 |
mouse |
| Alicia R Locker, Michael J Marks, Helen M Kamens, Laura Cousino Klei. Exposure to nicotine increases nicotinic acetylcholine receptor density in the reward pathway and binge ethanol consumption in C57BL/6J adolescent female mice. Brain research bulletin. vol 123. 2017-10-20. PMID:26428091. |
past studies report that nicotine and ethanol activate dopamine neurons in the reward pathway and may increase synaptic levels of dopamine in the nucleus accumbens through nicotinic acetylcholine receptor (nachr) stimulation. |
2017-10-20 |
2023-08-13 |
mouse |
| Pauline W Ondachi, Ana H Castro, Charles W Luetje, Charles R Wageman, Michael J Marks, M Imad Damaj, S Wayne Mascarella, Hernán A Navarro, F Ivy Carrol. Synthesis, Nicotinic Acetylcholine Binding, and in Vitro and in Vivo Pharmacological Properties of 2'-Fluoro-(carbamoylpyridinyl)deschloroepibatidine Analogues. ACS chemical neuroscience. vol 7. issue 7. 2017-10-19. PMID:27166021. |
2'-fluoro-(4-carbamoyl-3-pyridinyl)deschloroepitabidine (6a) displayed an attractive combination of properties, including subnanomolar binding affinity (ki = 0.07 nm), submicromolar inhibition of α4β2-nachrs in the functional assay (ic50 = 0.46 μm) with a high degree of selectivity for α4β2- relative to the α3β4/α7-nachrs (54-/348-fold, respectively), potent inhibition of [(3)h]dopamine release mediated by α4β2*- and α6β2*-nachrs in a synaptosomal preparation (ic50 = 21 and 32 nm, respectively), and an ad50 of 0.007 μg/kg as an antagonist of nicotine induced antinociception in the mouse tail-flick test which is 64 250 times more potent than dhβe. |
2017-10-19 |
2023-08-13 |
mouse |
| Natalia Omelchenko, Priya Roy, Judith Joyce Balcita-Pedicino, Samuel Poloyac, Susan R Sesac. Impact of prenatal nicotine on the structure of midbrain dopamine regions in the rat. Brain structure & function. vol 221. issue 4. 2017-10-03. PMID:25716298. |
impact of prenatal nicotine on the structure of midbrain dopamine regions in the rat. |
2017-10-03 |
2023-08-13 |
human |
| E van de Giessen, J J Weinstein, C M Cassidy, M Haney, Z Dong, R Ghazzaoui, N Ojeil, L S Kegeles, X Xu, N P Vadhan, N D Volkow, M Slifstein, A Abi-Dargha. Deficits in striatal dopamine release in cannabis dependence. Molecular psychiatry. vol 22. issue 1. 2017-09-29. PMID:27001613. |
to test whether cannabis dependence is associated with a similar dopaminergic deficit, we examined striatal and extrastriatal dopamine release in severely cannabis-dependent participants (cd), free of any comorbid conditions, including nicotine use. |
2017-09-29 |
2023-08-13 |
human |
| Kyoji Okita, Nicole Petersen, Chelsea L Robertson, Andy C Dean, Mark A Mandelkern, Edythe D Londo. Sex Differences in Midbrain Dopamine D2-Type Receptor Availability and Association with Nicotine Dependence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 12. 2017-09-11. PMID:27329684. |
sex differences in midbrain dopamine d2-type receptor availability and association with nicotine dependence. |
2017-09-11 |
2023-08-13 |
Not clear |
| Kyoji Okita, Nicole Petersen, Chelsea L Robertson, Andy C Dean, Mark A Mandelkern, Edythe D Londo. Sex Differences in Midbrain Dopamine D2-Type Receptor Availability and Association with Nicotine Dependence. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 12. 2017-09-11. PMID:27329684. |
because dopamine d2-type autoreceptors in the midbrain influence striatal dopamine release, a function that has been linked to addiction, we tested for sex differences in midbrain dopamine d2-type receptor bpnd and in relationships between midbrain bpnd, nicotine dependence and striatal dopamine d2-type receptor bpnd. |
2017-09-11 |
2023-08-13 |
Not clear |