| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Yuan Liu, Shuai Hao, Beibei Yang, Yi Fan, Xiaodong Qin, Yun Chen, Jun H. Wnt/β-catenin signaling plays an essential role in α7 nicotinic receptor-mediated neuroprotection of dopaminergic neurons in a mouse Parkinson's disease model. Biochemical pharmacology. vol 140. 2017-08-18. PMID:28551099. |
in the in vivo study, α7-nachr knockout (α7-ko) reversed the beneficial effects of nicotine on motor deficits, dopaminergic neuron loss, astrocyte and microglia activation, and reduced striatal dopamine release induced by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. |
2017-08-18 |
2023-08-13 |
mouse |
| Lena Rademacher, Susanne Prinz, Oliver Winz, Karsten Henkel, Claudia A Dietrich, Jörn Schmaljohann, Siamak Mohammadkhani Shali, Ina Schabram, Christian Stoppe, Paul Cumming, Ralf-Dieter Hilgers, Yoshitaka Kumakura, Mark Coburn, Felix M Mottaghy, Gerhard Gründer, Ingo Vernaleke. Effects of Smoking Cessation on Presynaptic Dopamine Function of Addicted Male Smokers. Biological psychiatry. vol 80. issue 3. 2017-08-07. PMID:26803340. |
there is evidence of abnormal cerebral dopamine transmission in nicotine-dependent smokers, but it is unclear whether dopaminergic abnormalities are due to acute nicotine abuse or whether they persist with abstinence. |
2017-08-07 |
2023-08-13 |
Not clear |
| Takuya Hikima, Marianela Garcia-Munoz, Gordon William Arbuthnot. Presynaptic D1 heteroreceptors and mGlu autoreceptors act at individual cortical release sites to modify glutamate release. Brain research. vol 1639. 2017-07-04. PMID:26944299. |
although most receptor agonizts (carbamylcholine, nicotine, dopamine d2, bdnf) did not affect electrically stimulated glu release, a significant increase was observed in the presence of metabotropic d1/d5 heteroreceptor agonist (skf38393 10µm) that was reversed by pka inhibitors. |
2017-07-04 |
2023-08-13 |
Not clear |
| Jessica L Koranda, Anne C Krok, Jian Xu, Anis Contractor, Daniel S McGehee, Jeff A Beeler, Xiaoxi Zhuan. Chronic Nicotine Mitigates Aberrant Inhibitory Motor Learning Induced by Motor Experience under Dopamine Deficiency. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 36. issue 19. 2017-06-26. PMID:27170121. |
chronic nicotine mitigates aberrant inhibitory motor learning induced by motor experience under dopamine deficiency. |
2017-06-26 |
2023-08-13 |
mouse |
| Pınar Kanlikilicer, Die Zhang, Andrei Dragomir, Yasemin M Akay, Metin Aka. Gene expression profiling of midbrain dopamine neurons upon gestational nicotine exposure. Medical & biological engineering & computing. vol 55. issue 3. 2017-06-05. PMID:27255453. |
gene expression profiling of midbrain dopamine neurons upon gestational nicotine exposure. |
2017-06-05 |
2023-08-13 |
Not clear |
| Pınar Kanlikilicer, Die Zhang, Andrei Dragomir, Yasemin M Akay, Metin Aka. Gene expression profiling of midbrain dopamine neurons upon gestational nicotine exposure. Medical & biological engineering & computing. vol 55. issue 3. 2017-06-05. PMID:27255453. |
ventral tegmental area dopamine (da) neurons in the mesocorticolimbic pathway were suggested to play a critical role in these pathological mechanisms induced by nicotine. |
2017-06-05 |
2023-08-13 |
Not clear |
| Robert L Haining, Travis M Jones, Aubrey Hernande. Saturation Binding of Nicotine to Synthetic Neuromelanin Demonstrated by Fluorescence Spectroscopy. Neurochemical research. vol 41. issue 12. 2017-03-15. PMID:27662849. |
using a uv/visible spectroscopic assay, we show that dopamine, 6-hydroxy dopamine, and nicotine bind to the synthetic neuromelanin, while caffeine did not. |
2017-03-15 |
2023-08-13 |
Not clear |
| Manoranjan S D'Souz. Neuroscience of nicotine for addiction medicine: novel targets for smoking cessation medications. Progress in brain research. vol 223. 2017-03-07. PMID:26806777. |
finally, the review will discuss the role of classical neurotransmitters (dopamine, serotonin, noradrenaline, glutamate, and γ-aminobutyric acid) as well as endogenous opioid and endocannabinoid signaling in nicotine dependence. |
2017-03-07 |
2023-08-13 |
Not clear |
| Masatoshi Inden, Kazuyuki Takata, Daijiro Yanagisawa, Eishi Ashihara, Ikuo Tooyama, Shun Shimohama, Yoshihisa Kitamur. α4 nicotinic acetylcholine receptor modulated by galantamine on nigrostriatal terminals regulates dopamine receptor-mediated rotational behavior. Neurochemistry international. vol 94. 2017-01-19. PMID:26911419. |
when 6-ohda-injected rats were co-treated with nomifensine, a dopamine transporter inhibitor, a more pronounced and a remarkable effect of nicotine and galantamine was observed. |
2017-01-19 |
2023-08-13 |
rat |
| Masatoshi Inden, Kazuyuki Takata, Daijiro Yanagisawa, Eishi Ashihara, Ikuo Tooyama, Shun Shimohama, Yoshihisa Kitamur. α4 nicotinic acetylcholine receptor modulated by galantamine on nigrostriatal terminals regulates dopamine receptor-mediated rotational behavior. Neurochemistry international. vol 94. 2017-01-19. PMID:26911419. |
under these conditions, the combination of nomifensine with nicotine or galantamine induced the ipsilateral rotation similar to the methamphetamine-induced rotational behavior, indicating that nicotine and galantamine also induce dopamine release from striatal terminals. |
2017-01-19 |
2023-08-13 |
rat |
| Judit Zsuga, Gabor Tajti, Csaba Papp, Bela Juhasz, Rudolf Gesztely. FNDC5/irisin, a molecular target for boosting reward-related learning and motivation. Medical hypotheses. vol 90. 2017-01-06. PMID:27063080. |
while nicotine and alcohol alter dopamine neuron function by influencing some receptors, mesocortico-limbic system dysfunction was associated with elevation of metabolic set-point leading to hedonic over-eating. |
2017-01-06 |
2023-08-13 |
Not clear |
| Eric A Engleman, Simon N Katner, Bethany S Neal-Belivea. Caenorhabditis elegans as a Model to Study the Molecular and Genetic Mechanisms of Drug Addiction. Progress in molecular biology and translational science. vol 137. 2016-12-30. PMID:26810004. |
c. elegans has also been shown to display dopamine and cholinergic system-dependent attraction to nicotine and demonstrate preference for cues previously associated with nicotine. |
2016-12-30 |
2023-08-13 |
human |
| Dawei Qi, Qian Zhang, Wanhong Zhou, Jingjing Zhao, Bo Zhang, Yunfei Sha, Zhiqing Pan. Quantification of Dopamine in Brain Microdialysates with High-Performance Liquid Chromatography-Tandem Mass Spectrometry. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. vol 32. issue 4. 2016-12-20. PMID:27063714. |
the dopamine level in the brain and the mesolimbick dopaminergic system are responsible for nicotine addiction. |
2016-12-20 |
2023-08-13 |
rat |
| Dawei Qi, Qian Zhang, Wanhong Zhou, Jingjing Zhao, Bo Zhang, Yunfei Sha, Zhiqing Pan. Quantification of Dopamine in Brain Microdialysates with High-Performance Liquid Chromatography-Tandem Mass Spectrometry. Analytical sciences : the international journal of the Japan Society for Analytical Chemistry. vol 32. issue 4. 2016-12-20. PMID:27063714. |
finally, the dopamine concentrations in the rat brain microdialysates were determined, and the pharmacokinetics of extracellular dopamine in the brain nucleus accumbens after an intravenous injection of nicotine was successfully evaluated. |
2016-12-20 |
2023-08-13 |
rat |
| W Goutier, J P Lowry, A C McCreary, J J O'Conno. Frequency-Dependent Modulation of Dopamine Release by Nicotine and Dopamine D1 Receptor Ligands: An In Vitro Fast Cyclic Voltammetry Study in Rat Striatum. Neurochemical research. vol 41. issue 5. 2016-12-13. PMID:26975318. |
frequency-dependent modulation of dopamine release by nicotine and dopamine d1 receptor ligands: an in vitro fast cyclic voltammetry study in rat striatum. |
2016-12-13 |
2023-08-13 |
rat |
| W Goutier, J P Lowry, A C McCreary, J J O'Conno. Frequency-Dependent Modulation of Dopamine Release by Nicotine and Dopamine D1 Receptor Ligands: An In Vitro Fast Cyclic Voltammetry Study in Rat Striatum. Neurochemical research. vol 41. issue 5. 2016-12-13. PMID:26975318. |
nicotine is a highly addictive drug and exerts this effect partially through the modulation of dopamine release and increasing extracellular dopamine in regions such as the brain reward systems. |
2016-12-13 |
2023-08-13 |
rat |
| W Goutier, J P Lowry, A C McCreary, J J O'Conno. Frequency-Dependent Modulation of Dopamine Release by Nicotine and Dopamine D1 Receptor Ligands: An In Vitro Fast Cyclic Voltammetry Study in Rat Striatum. Neurochemical research. vol 41. issue 5. 2016-12-13. PMID:26975318. |
the effect of nicotine on the frequency dependent modulation of dopamine release is well established and the purpose of this study was to investigate whether dopamine d1 receptor (d1r) ligands have an influence on this. |
2016-12-13 |
2023-08-13 |
rat |
| W Goutier, J P Lowry, A C McCreary, J J O'Conno. Frequency-Dependent Modulation of Dopamine Release by Nicotine and Dopamine D1 Receptor Ligands: An In Vitro Fast Cyclic Voltammetry Study in Rat Striatum. Neurochemical research. vol 41. issue 5. 2016-12-13. PMID:26975318. |
using fast cyclic voltammetry and rat corticostriatal slices, we show that d1r ligands are able to modulate the effect of nicotine on dopamine release. |
2016-12-13 |
2023-08-13 |
rat |
| W Goutier, J P Lowry, A C McCreary, J J O'Conno. Frequency-Dependent Modulation of Dopamine Release by Nicotine and Dopamine D1 Receptor Ligands: An In Vitro Fast Cyclic Voltammetry Study in Rat Striatum. Neurochemical research. vol 41. issue 5. 2016-12-13. PMID:26975318. |
nicotine (500 nm) induced a decrease in dopamine efflux at low frequency (single pulse or five pulses at 10 hz) and an increase at high frequency (100 hz) electrical field stimulation. |
2016-12-13 |
2023-08-13 |
rat |
| W Goutier, J P Lowry, A C McCreary, J J O'Conno. Frequency-Dependent Modulation of Dopamine Release by Nicotine and Dopamine D1 Receptor Ligands: An In Vitro Fast Cyclic Voltammetry Study in Rat Striatum. Neurochemical research. vol 41. issue 5. 2016-12-13. PMID:26975318. |
the d1r agonist skf-38393, whilst having no effect on dopamine release on its own or on the effect of nicotine upon multiple pulse evoked dopamine release, did significantly prevent and reverse the effect of nicotine on single pulse dopamine release. |
2016-12-13 |
2023-08-13 |
rat |