| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Matthew I Palmatier, Marissa R Kellicut, A Brianna Sheppard, Russell W Brown, Donita L Robinso. The incentive amplifying effects of nicotine are reduced by selective and non-selective dopamine antagonists in rats. Pharmacology, biochemistry, and behavior. vol 126. 2015-11-09. PMID:25230311. |
incentive motivation and sign tracking are mediated by mesolimbic dopamine (da) transmission and nicotine facilitates mesolimbic da release. |
2015-11-09 |
2023-08-13 |
rat |
| Richard Exley, Michael A Clements, Henrike Hartung, J Michael McIntosh, Michael Franklin, Isabel Bermudez, Stephanie J Crag. Striatal dopamine transmission is reduced after chronic nicotine with a decrease in α6-nicotinic receptor control in nucleus accumbens. The European journal of neuroscience. vol 38. issue 7. 2015-10-30. PMID:23841846. |
striatal dopamine transmission is reduced after chronic nicotine with a decrease in α6-nicotinic receptor control in nucleus accumbens. |
2015-10-30 |
2023-08-12 |
mouse |
| Richard Exley, Michael A Clements, Henrike Hartung, J Michael McIntosh, Michael Franklin, Isabel Bermudez, Stephanie J Crag. Striatal dopamine transmission is reduced after chronic nicotine with a decrease in α6-nicotinic receptor control in nucleus accumbens. The European journal of neuroscience. vol 38. issue 7. 2015-10-30. PMID:23841846. |
nicotine directly regulates striatal dopamine (da) neurotransmission via presynaptic nicotinic acetylcholine receptors (nachrs) that are α6β2 and/or α4β2 subunit-containing, depending on region. |
2015-10-30 |
2023-08-12 |
mouse |
| Masanori Ohmoto, Tatsuo Takahashi, Yoko Kubota, Shinjiro Kobayashi, Yasuhide Mitsumot. Genetic influence of dopamine receptor, dopamine transporter, and nicotine metabolism on smoking cessation and nicotine dependence in a Japanese population. BMC genetics. vol 15. 2015-10-01. PMID:25526961. |
genetic influence of dopamine receptor, dopamine transporter, and nicotine metabolism on smoking cessation and nicotine dependence in a japanese population. |
2015-10-01 |
2023-08-13 |
human |
| Masanori Ohmoto, Tatsuo Takahashi, Yoko Kubota, Shinjiro Kobayashi, Yasuhide Mitsumot. Genetic influence of dopamine receptor, dopamine transporter, and nicotine metabolism on smoking cessation and nicotine dependence in a Japanese population. BMC genetics. vol 15. 2015-10-01. PMID:25526961. |
this study investigated whether polymorphisms of the ankyrin repeat and kinase domain containing 1 gene (ankk1), which is adjacent to the dopamine d2 receptor gene (drd2), and the dopamine transporter (slc6a3) and cytochrome p450 2a6 (cyp2a6) genes influence smoking cessation and nicotine dependence in a japanese population. |
2015-10-01 |
2023-08-13 |
human |
| Staci E Engle, J Michael McIntosh, Ryan M Drena. Nicotine and ethanol cooperate to enhance ventral tegmental area AMPA receptor function via α6-containing nicotinic receptors. Neuropharmacology. vol 91. 2015-09-28. PMID:25484253. |
nicotine + ethanol co-exposure results in additive and/or synergistic effects in the ventral tegmental area (vta) to nucleus accumbens (nac) dopamine (da) pathway, but the mechanisms supporting this are unclear. |
2015-09-28 |
2023-08-13 |
mouse |
| Oscar V Torres, Joseph A Pipkin, Patrick Ferree, Luis M Carcoba, Laura E O'Del. Nicotine withdrawal increases stress-associated genes in the nucleus accumbens of female rats in a hormone-dependent manner. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. vol 17. issue 4. 2015-09-10. PMID:25762751. |
previous work led to our hypothesis that sex differences produced by nicotine withdrawal are modulated by stress and dopamine systems in the nucleus accumbens (nacc). |
2015-09-10 |
2023-08-13 |
rat |
| Kelly P Cosgrove, Irina Esterlis, Christine Sandiego, Ryan Petrulli, Evan D Morri. Imaging Tobacco Smoking with PET and SPECT. Current topics in behavioral neurosciences. vol 24. 2015-09-08. PMID:25638332. |
nicotine, the primary addictive chemical in tobacco smoke, enters the brain, activates beta2-nicotinic acetylcholine receptors (β2*-nachrs) and, like most drugs of abuse, elicits dopamine (da) release in the ventral striatum. |
2015-09-08 |
2023-08-13 |
human |
| David J K Balfou. The role of mesoaccumbens dopamine in nicotine dependence. Current topics in behavioral neurosciences. vol 24. 2015-09-08. PMID:25638334. |
the role of mesoaccumbens dopamine in nicotine dependence. |
2015-09-08 |
2023-08-13 |
Not clear |
| Julie-Anne Tanner, Meghan J Chenoweth, Rachel F Tyndal. Pharmacogenetics of nicotine and associated smoking behaviors. Current topics in behavioral neurosciences. vol 23. 2015-09-08. PMID:25655887. |
binding of nicotine to neuronal nicotinic acetylcholine receptors (nachrs) mediates the release of several neurotransmitters including dopamine and serotonin. |
2015-09-08 |
2023-08-13 |
Not clear |
| Tanuja Bordia, J Michael McIntosh, Maryka Qui. The nicotine-mediated decline in l-dopa-induced dyskinesias is associated with a decrease in striatal dopamine release. Journal of neurochemistry. vol 125. issue 2. 2015-08-18. PMID:23373725. |
nicotine treatment led to declines in the striatal dopamine transporter, α6β2* nachrs and various components of α6β2* and α4β2* nachr-mediated release. |
2015-08-18 |
2023-08-12 |
rat |
| Manindra Nath Tiwari, Swati Agarwal, Priyanka Bhatnagar, Naveen Kumar Singhal, Shashi Kant Tiwari, Pradeep Kumar, Lalit Kumar Singh Chauhan, Devendra Kumar Patel, Rajnish Kumar Chaturvedi, Mahendra Pratap Singh, Kailash Chand Gupt. Nicotine-encapsulated poly(lactic-co-glycolic) acid nanoparticles improve neuroprotective efficacy against MPTP-induced parkinsonism. Free radical biology & medicine. vol 65. 2015-08-07. PMID:23933227. |
the levels of dopamine and its metabolites were measured in the striatum, nicotine and its metabolite in the nigrostriatal tissues while the immunoreactivities of tyrosine hydroxylase (th), metallothionein-iii (mt-iii), inducible nitric oxide synthase (inos) and microglial activation were checked in the substantia nigra of controls and treated mice. |
2015-08-07 |
2023-08-12 |
mouse |
| Laura E O'Dell, Luis A Natividad, Joseph A Pipkin, Francisco Roman, Ivan Torres, Jesus Jurado, Oscar V Torres, Theodore C Friedman, John M Tenayuca, Arbi Nazaria. Enhanced nicotine self-administration and suppressed dopaminergic systems in a rat model of diabetes. Addiction biology. vol 19. issue 6. 2015-07-20. PMID:23834715. |
in order to examine the contribution of dopamine to our behavioral effects, dopamine transporter (dat), d1 and d2 receptor levels were compared in the nucleus accumbens (nac) following 10 days of nicotine or saline ivsa. |
2015-07-20 |
2023-08-12 |
rat |
| Laura E O'Dell, Luis A Natividad, Joseph A Pipkin, Francisco Roman, Ivan Torres, Jesus Jurado, Oscar V Torres, Theodore C Friedman, John M Tenayuca, Arbi Nazaria. Enhanced nicotine self-administration and suppressed dopaminergic systems in a rat model of diabetes. Addiction biology. vol 19. issue 6. 2015-07-20. PMID:23834715. |
dopamine levels in the nac were also compared following nicotine administration. |
2015-07-20 |
2023-08-12 |
rat |
| Laura E O'Dell, Luis A Natividad, Joseph A Pipkin, Francisco Roman, Ivan Torres, Jesus Jurado, Oscar V Torres, Theodore C Friedman, John M Tenayuca, Arbi Nazaria. Enhanced nicotine self-administration and suppressed dopaminergic systems in a rat model of diabetes. Addiction biology. vol 19. issue 6. 2015-07-20. PMID:23834715. |
stz-treated rats also displayed suppressed nac dopamine levels during baseline and in response to nicotine. |
2015-07-20 |
2023-08-12 |
rat |
| Maram A T M Khaled, Abhiram Pushparaj, Patricia Di Ciano, Jorge Diaz, Bernard Le Fol. Dopamine D3 receptors in the basolateral amygdala and the lateral habenula modulate cue-induced reinstatement of nicotine seeking. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 13. 2015-07-07. PMID:24998621. |
dopamine d3 receptors in the basolateral amygdala and the lateral habenula modulate cue-induced reinstatement of nicotine seeking. |
2015-07-07 |
2023-08-13 |
rat |
| David J Nutt, Anne Lingford-Hughes, David Erritzoe, Paul R A Stoke. The dopamine theory of addiction: 40 years of highs and lows. Nature reviews. Neuroscience. vol 16. issue 5. 2015-06-22. PMID:25873042. |
moreover, there is good evidence that striatal dopamine receptor availability and dopamine release are diminished in individuals with stimulant or alcohol dependence but not in individuals with opiate, nicotine or cannabis dependence. |
2015-06-22 |
2023-08-13 |
human |
| C Morel, L Fattore, S Pons, Y A Hay, F Marti, B Lambolez, M De Biasi, M Lathrop, W Fratta, U Maskos, P Faur. Nicotine consumption is regulated by a human polymorphism in dopamine neurons. Molecular psychiatry. vol 19. issue 8. 2015-05-11. PMID:24296975. |
nicotine consumption is regulated by a human polymorphism in dopamine neurons. |
2015-05-11 |
2023-08-12 |
mouse |
| Xiaosi Gu, Terry Lohrenz, Ramiro Salas, Philip R Baldwin, Alireza Soltani, Ulrich Kirk, Paul M Cinciripini, P Read Montagu. Belief about nicotine selectively modulates value and reward prediction error signals in smokers. Proceedings of the National Academy of Sciences of the United States of America. vol 112. issue 8. 2015-05-01. PMID:25605923. |
using a model-based approach, we show that smokers' beliefs about nicotine specifically modulated learning signals (value and reward prediction error) defined by a computational model of mesolimbic dopamine systems. |
2015-05-01 |
2023-08-13 |
human |
| Elise M Weerts, Gary S Wand, Hiroto Kuwabara, Xiaoqiang Xu, J James Frost, Dean F Wong, Mary E McCau. Association of smoking with μ-opioid receptor availability before and during naltrexone blockade in alcohol-dependent subjects. Addiction biology. vol 19. issue 4. 2015-04-20. PMID:23252742. |
the high levels of comorbidity of nicotine and alcohol use and dependence are thought to be related to interactions between nicotinic, opioid and dopamine receptors in mesolimbic regions. |
2015-04-20 |
2023-08-12 |
human |