| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S K Sudakov, G A Nazarova, E V Alekseeva, A A Kolpako. Effect of activated peripheral κ-opioid receptors on the action of nicotine and its withdrawal in nicotine-dependent rats. Bulletin of experimental biology and medicine. vol 156. issue 5. 2014-12-10. PMID:24770739. |
it can be hypothesized that nicotine withdrawal syndrome is related to inhibition of dopamine release in the nucleus accumbens probably caused by enhanced κ-opioid activity in presynaptic terminals. |
2014-12-10 |
2023-08-13 |
human |
| Alessia Salamone, Stefania Zappettini, Massimo Grilli, Guendalina Olivero, Paula Agostinho, Angelo R Tomé, Jiayang Chen, Anna Pittaluga, Rodrigo A Cunha, Mario March. Prolonged nicotine exposure down-regulates presynaptic NMDA receptors in dopaminergic terminals of the rat nucleus accumbens. Neuropharmacology. vol 79. 2014-12-03. PMID:24373903. |
most nac dopaminergic terminals possessed the nachr α4 subunit and the pre-exposure of synaptosomes to nicotine (30 μm) or to the α4β2-containing nachr agonist 5ia85380 (10 nm) selectively inhibited the nmda (100 μm)-evoked, but not the 4-aminopyridine (10 μm)-evoked, [(3)h] dopamine outflow; this inhibition was blunted by mecamylamine (10 μm). |
2014-12-03 |
2023-08-12 |
rat |
| Tania Ávila-Ruiz, Vladimir Carranza, López-López Gustavo, Daniel I Limón, Isabel Martínez, Gonzalo Flores, Jorge Flores-Hernánde. Chronic administration of nicotine enhances NMDA-activated currents in the prefrontal cortex and core part of the nucleus accumbens of rats. Synapse (New York, N.Y.). vol 68. issue 6. 2014-11-28. PMID:24549882. |
it has been suggested that nicotine acts on glutamatergic (n-methyl-d-aspartate, nmda) neurotransmission affecting dopamine release in the mesocorticolimbic system. |
2014-11-28 |
2023-08-12 |
rat |
| Maria Pannell, Frank Szulzewsky, Vitali Matyash, Susanne A Wolf, Helmut Kettenman. The subpopulation of microglia sensitive to neurotransmitters/neurohormones is modulated by stimulation with LPS, interferon-γ, and IL-4. Glia. vol 62. issue 5. 2014-11-24. PMID:24504982. |
we freshly isolated microglia from healthy adult c57bl/6 mice and found that only a small fraction (1-20%) responded to the application of endothelin, histamine, substance p, serotonin, galanin, somatostatin, angiotensin ii, vasopressin, neurotensin, dopamine, or nicotine. |
2014-11-24 |
2023-08-12 |
mouse |
| Rebecca L Ashare, E Paul Wileyto, Kosha Ruparel, Patricia M Goelz, Ryan D Hopson, Jeffrey N Valdez, Ruben C Gur, James Loughead, Caryn Lerma. Effects of tolcapone on working memory and brain activity in abstinent smokers: a proof-of-concept study. Drug and alcohol dependence. vol 133. issue 3. 2014-11-14. PMID:24095246. |
dopamine levels in the prefrontal cortex (pfc) are thought to play an important role in cognitive function and nicotine dependence. |
2014-11-14 |
2023-08-12 |
Not clear |
| Peter A Crooks, Michael T Bardo, Linda P Dwoski. Nicotinic receptor antagonists as treatments for nicotine abuse. Advances in pharmacology (San Diego, Calif.). vol 69. 2014-11-06. PMID:24484986. |
the rewarding effects of nicotine are mediated, in part, by nicotine-evoked dopamine (da) release leading to sensitization, which is associated with repeated nicotine administration and nicotine addiction. |
2014-11-06 |
2023-08-12 |
rat |
| George A Buzzell, John R Fedota, Daniel M Roberts, Craig G McDonal. The N2 ERP component as an index of impaired cognitive control in smokers. Neuroscience letters. vol 563. 2014-10-24. PMID:24486891. |
impaired cognitive control has been proposed as a hallmark of nicotine dependence and is thought to arise, in part, from synaptic alterations in anterior cingulate cortex (acc), a primary component of the dopamine reward pathway. |
2014-10-24 |
2023-08-12 |
Not clear |
| Yan-You Huang, Amir Levine, Denise B Kandel, Deqi Yin, Luca Colnaghi, Bettina Drisaldi, Eric R Kande. D1/D5 receptors and histone deacetylation mediate the Gateway Effect of LTP in hippocampal dentate gyrus. Learning & memory (Cold Spring Harbor, N.Y.). vol 21. issue 3. 2014-10-12. PMID:24549570. |
the facilitation induced by nicotine and cocaine can be blocked by oral administration of the dopamine d1/d5 receptor antagonist (skf 83566) and enhanced by the d1/d5 agonist (skf 38393). |
2014-10-12 |
2023-08-12 |
mouse |
| Celina Y Mojica, Jasmin M Dao, Menglu Yuan, Sandra E Loughlin, Frances M Lesli. Nicotine modulation of adolescent dopamine receptor signaling and hypothalamic peptide response. Neuropharmacology. vol 77. 2014-08-26. PMID:24157491. |
these findings suggest that adolescent dopamine and crf systems are vulnerable to alteration by nicotine. |
2014-08-26 |
2023-08-12 |
rat |
| Die Zhang, Andrei Dragomir, Yasemin M Akay, Metin Aka. Nicotine exposure increases the complexity of dopamine neurons in the parainterfascicular nucleus (PIF) sub-region of VTA. Journal of neuroengineering and rehabilitation. vol 11. 2014-08-22. PMID:24920473. |
nicotine exposure increases the complexity of dopamine neurons in the parainterfascicular nucleus (pif) sub-region of vta. |
2014-08-22 |
2023-08-13 |
Not clear |
| Kirsty Danielson, Fraser Putt, Penelope Truman, Bronwyn M Kivel. The effects of nicotine and tobacco particulate matter on dopamine uptake in the rat brain. Synapse (New York, N.Y.). vol 68. issue 2. 2014-08-11. PMID:23999947. |
the effects of nicotine and tobacco particulate matter on dopamine uptake in the rat brain. |
2014-08-11 |
2023-08-12 |
rat |
| Kirsty Danielson, Fraser Putt, Penelope Truman, Bronwyn M Kivel. The effects of nicotine and tobacco particulate matter on dopamine uptake in the rat brain. Synapse (New York, N.Y.). vol 68. issue 2. 2014-08-11. PMID:23999947. |
nicotine is known to affect the uptake of dopamine in the brain of laboratory animals, but studies in the literature are often contradictory and little is known of the effects on non-nicotinic tobacco components on dopamine uptake. |
2014-08-11 |
2023-08-12 |
rat |
| Kirsty Danielson, Fraser Putt, Penelope Truman, Bronwyn M Kivel. The effects of nicotine and tobacco particulate matter on dopamine uptake in the rat brain. Synapse (New York, N.Y.). vol 68. issue 2. 2014-08-11. PMID:23999947. |
this study has examined the acute and chronic effects of nicotine and a tobacco extract (tpm) on dopamine uptake by the dopamine and norepinephrine transporters (dat and net) ex vivo using rotating disk electrode voltammetry, and quantified dat and net protein and mrna expression in key brain regions. |
2014-08-11 |
2023-08-12 |
rat |
| Jessica L Koranda, Jackson J Cone, Daniel S McGehee, Mitchell F Roitman, Jeff A Beeler, Xiaoxi Zhuan. Nicotinic receptors regulate the dynamic range of dopamine release in vivo. Journal of neurophysiology. vol 111. issue 1. 2014-08-11. PMID:24089398. |
deletion of β2*nachrs and chronic nicotine exposure greatly diminished dopamine release across the entire range of stimulation parameters. |
2014-08-11 |
2023-08-12 |
mouse |
| Jessica L Koranda, Jackson J Cone, Daniel S McGehee, Mitchell F Roitman, Jeff A Beeler, Xiaoxi Zhuan. Nicotinic receptors regulate the dynamic range of dopamine release in vivo. Journal of neurophysiology. vol 111. issue 1. 2014-08-11. PMID:24089398. |
in addition, we observed a facilitation of dopamine release at low frequency and pulse number in wild-type mice that is absent in the β2* knockout and chronic nicotine mice. |
2014-08-11 |
2023-08-12 |
mouse |
| Laura E O'Dell, Oscar V Torre. A mechanistic hypothesis of the factors that enhance vulnerability to nicotine use in females. Neuropharmacology. vol 76 Pt B. 2014-07-29. PMID:23684991. |
we also provide a neural framework whereby estrogen promotes greater rewarding effects of nicotine in females via enhanced dopamine release in the nucleus accumbens (nacc). |
2014-07-29 |
2023-08-12 |
rat |
| Tetsuya Matsuura, Hitoshi Miura, Asuka Nishin. Inhibition of gustatory plasticity due to acute nicotine exposure in the nematode Caenorhabditis elegans. Neuroscience research. vol 77. issue 3. 2014-07-29. PMID:24025430. |
inhibition of gustatory plasticity was observed when cat-2 mutants with a defect in dopamine biosynthesis were pre-exposed to nacl with 3.0mm nicotine. |
2014-07-29 |
2023-08-12 |
caenorhabditis_elegans |
| Tetsuya Matsuura, Hitoshi Miura, Asuka Nishin. Inhibition of gustatory plasticity due to acute nicotine exposure in the nematode Caenorhabditis elegans. Neuroscience research. vol 77. issue 3. 2014-07-29. PMID:24025430. |
acute nicotine exposure did not cause inhibition of gustatory plasticity in bas-1 mutants, which had defects in both serotonin and dopamine secretion, and tph-1 mutants, which had a defect in serotonin secretion only. |
2014-07-29 |
2023-08-12 |
caenorhabditis_elegans |
| Chao Wang, Wei Qian, Minming Zhan. [Advance in studies on dopamine system related genetic polymorphisms associated with nicotine dependence]. Zhonghua yi xue yi chuan xue za zhi = Zhonghua yixue yichuanxue zazhi = Chinese journal of medical genetics. vol 31. issue 3. 2014-07-29. PMID:24928014. |
release of dopamine has been considered the most important channel for nicotine dependence. |
2014-07-29 |
2023-08-13 |
Not clear |
| E M Hill-Burns, N Singh, P Ganguly, T H Hamza, J Montimurro, D M Kay, D Yearout, P Sheehan, K Frodey, J A McLear, M B Feany, S D Hanes, W J Wolfgang, C P Zabetian, S A Factor, H Payam. A genetic basis for the variable effect of smoking/nicotine on Parkinson's disease. The pharmacogenomics journal. vol 13. issue 6. 2014-07-14. PMID:23032990. |
sv2c is biologically plausible because nicotine enhances the release of dopamine through synaptic vesicles, and pd is caused by the depletion of dopamine. |
2014-07-14 |
2023-08-12 |
drosophila_melanogaster |