| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Malou Dongelmans, Romain Durand-de Cuttoli, Claire Nguyen, Maxime Come, Etienne K Duranté, Damien Lemoine, Raphaël Brito, Tarek Ahmed Yahia, Sarah Mondoloni, Steve Didienne, Elise Bousseyrol, Bernadette Hannesse, Lauren M Reynolds, Nicolas Torquet, Deniz Dalkara, Fabio Marti, Alexandre Mourot, Jérémie Naudé, Philippe Faur. Chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice. Nature communications. vol 12. issue 1. 2021-11-29. PMID:34836948. |
chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice. |
2021-11-29 |
2023-08-13 |
mouse |
| Malou Dongelmans, Romain Durand-de Cuttoli, Claire Nguyen, Maxime Come, Etienne K Duranté, Damien Lemoine, Raphaël Brito, Tarek Ahmed Yahia, Sarah Mondoloni, Steve Didienne, Elise Bousseyrol, Bernadette Hannesse, Lauren M Reynolds, Nicolas Torquet, Deniz Dalkara, Fabio Marti, Alexandre Mourot, Jérémie Naudé, Philippe Faur. Chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice. Nature communications. vol 12. issue 1. 2021-11-29. PMID:34836948. |
using an intracranial self-stimulation reward-based foraging task, we investigated in mice the impact of chronic nicotine on midbrain dopamine neuron activity and its consequence on the trade-off between exploitation and exploration. |
2021-11-29 |
2023-08-13 |
mouse |
| Malou Dongelmans, Romain Durand-de Cuttoli, Claire Nguyen, Maxime Come, Etienne K Duranté, Damien Lemoine, Raphaël Brito, Tarek Ahmed Yahia, Sarah Mondoloni, Steve Didienne, Elise Bousseyrol, Bernadette Hannesse, Lauren M Reynolds, Nicolas Torquet, Deniz Dalkara, Fabio Marti, Alexandre Mourot, Jérémie Naudé, Philippe Faur. Chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice. Nature communications. vol 12. issue 1. 2021-11-29. PMID:34836948. |
we then mimicked the effect of chronic nicotine on the tonic activity of dopamine neurons using optogenetics, and found that photo-stimulated mice adopted a behavioral phenotype similar to that of mice exposed to chronic nicotine. |
2021-11-29 |
2023-08-13 |
mouse |
| Malou Dongelmans, Romain Durand-de Cuttoli, Claire Nguyen, Maxime Come, Etienne K Duranté, Damien Lemoine, Raphaël Brito, Tarek Ahmed Yahia, Sarah Mondoloni, Steve Didienne, Elise Bousseyrol, Bernadette Hannesse, Lauren M Reynolds, Nicolas Torquet, Deniz Dalkara, Fabio Marti, Alexandre Mourot, Jérémie Naudé, Philippe Faur. Chronic nicotine increases midbrain dopamine neuron activity and biases individual strategies towards reduced exploration in mice. Nature communications. vol 12. issue 1. 2021-11-29. PMID:34836948. |
our results reveal a key role of tonic midbrain dopamine in the exploration/exploitation trade-off and highlight a potential mechanism by which nicotine affects the exploration/exploitation balance and decision-making. |
2021-11-29 |
2023-08-13 |
mouse |
| P Berveiller, E Rault, P Guerb. [Physiological and Psychological Data influencing Pregnant Women Smoking Behavior - CNGOF-SFT Expert Report and Guidelines for Smoking Management during Pregnancy]. Gynecologie, obstetrique, fertilite & senologie. vol 48. issue 7-8. 2021-11-24. PMID:32247097. |
nicotine is the main addictive substance in tobacco and its addictive effects mainly involve dopamine. |
2021-11-24 |
2023-08-13 |
Not clear |
| Maryam Sardari, Masoud Seddighfar, Sara Sardar. Dopamine receptors in the anterior cingulate cortex implicate in nicotine enhanced morphine analgesia. Psychopharmacology. vol 238. issue 11. 2021-11-23. PMID:34383109. |
dopamine receptors in the anterior cingulate cortex implicate in nicotine enhanced morphine analgesia. |
2021-11-23 |
2023-08-13 |
Not clear |
| Wesley Drew Gill, Katherine C Burgess, Cynthia Vied, Russell W Brow. Transgenerational evidence of increases in dopamine D2 receptor sensitivity in rodents: Impact on sensorimotor gating, the behavioral response to nicotine and BDNF. Journal of psychopharmacology (Oxford, England). vol 35. issue 10. 2021-10-26. PMID:34291671. |
transgenerational evidence of increases in dopamine d2 receptor sensitivity in rodents: impact on sensorimotor gating, the behavioral response to nicotine and bdnf. |
2021-10-26 |
2023-08-13 |
rat |
| Steven R Laviolett. Molecular and neuronal mechanisms underlying the effects of adolescent nicotine exposure on anxiety and mood disorders. Neuropharmacology. vol 184. 2021-10-22. PMID:33245960. |
nicotine can potently regulate the transmission of various neurochemicals, including dopamine (da), γ-amino-butyric acid (gaba) and glutamate, within various mesocorticolimbic structures, such as the ventral tegmental area (vta), nucleus accumbens (nac) and prefrontal cortex (pfc), all of which show pathologies in these disorders. |
2021-10-22 |
2023-08-13 |
Not clear |
| Angel Carvajal-Oliveros, Carmen Domínguez-Baleón, Rafaella V Zárate, Jorge M Campusano, Verónica Narváez-Padilla, Enrique Reynau. Nicotine suppresses Parkinson's disease like phenotypes induced by Synphilin-1 overexpression in Drosophila melanogaster by increasing tyrosine hydroxylase and dopamine levels. Scientific reports. vol 11. issue 1. 2021-10-22. PMID:33953275. |
nicotine suppresses parkinson's disease like phenotypes induced by synphilin-1 overexpression in drosophila melanogaster by increasing tyrosine hydroxylase and dopamine levels. |
2021-10-22 |
2023-08-13 |
drosophila_melanogaster |
| Angel Carvajal-Oliveros, Carmen Domínguez-Baleón, Rafaella V Zárate, Jorge M Campusano, Verónica Narváez-Padilla, Enrique Reynau. Nicotine suppresses Parkinson's disease like phenotypes induced by Synphilin-1 overexpression in Drosophila melanogaster by increasing tyrosine hydroxylase and dopamine levels. Scientific reports. vol 11. issue 1. 2021-10-22. PMID:33953275. |
nicotine is beneficial on fly survival and motility increasing tyrosine hydroxylase and dopamine levels, suggesting that cholinergic agonists may promote survival and metabolic function of the dopaminergic neurons that express sph-1. |
2021-10-22 |
2023-08-13 |
drosophila_melanogaster |
| Andrew M Smith, Linda P Dwoskin, James R Paul. Early exposure to nicotine during critical periods of brain development: Mechanisms and consequences. Journal of pediatric biochemistry. vol 1. issue 2. 2021-10-21. PMID:24904708. |
the purpose of the current review is to provide an overview of the role that nicotinic achrs play in the developing cns and to describe the effects of nicotine exposure during early development on neuronal cell biology, nicotinic achr expression and neurotransmitter system (e.g., dopamine, norepinephrine, serotonin) function. |
2021-10-21 |
2023-08-13 |
Not clear |
| Katina C Calakos, Ansel T Hillmer, Gustavo A Angarita, Stephen R Baldassarri, Soheila Najafzadeh, Paul R Emery, David Matuskey, Yiyun Huang, Kelly P Cosgrov. Recently abstinent smokers exhibit mood-associated dopamine dysfunction in the ventral striatum compared to nonsmokers: a [11C]-(+)-PHNO PET study. Nicotine & tobacco research : official journal of the Society for Research on Nicotine and Tobacco. 2021-10-10. PMID:34628508. |
chronic nicotine exposure desensitizes dopamine responses in animals, but it is not known if this occurs in human tobacco smokers. |
2021-10-10 |
2023-08-13 |
human |
| Jing Luo, Li-Hua Bian, Zi-Wei Yao, Xiao-Mei Wang, Qiu-Yu Li, Jian-You Guo, Jin-Li Sh. Anthocyanins in Lycium ruthenicum Murray reduce nicotine withdrawal-induced anxiety and craving in mice. Neuroscience letters. vol 763. 2021-10-01. PMID:34384845. |
it was speculated that alrm was involved in the production and transmission of dopamine, choline, and other nervous system functions and exhibited a potential role in treating nicotine addiction. |
2021-10-01 |
2023-08-13 |
mouse |
| Michael Wolter, Thomas Lapointe, Brett Melanson, Nana Baidoo, Travis Francis, Boyer D Winters, Francesco Ler. Memory enhancing effects of nicotine, cocaine, and their conditioned stimuli; effects of beta-adrenergic and dopamine D2 receptor antagonists. Psychopharmacology. vol 238. issue 9. 2021-09-28. PMID:34175982. |
memory enhancing effects of nicotine, cocaine, and their conditioned stimuli; effects of beta-adrenergic and dopamine d2 receptor antagonists. |
2021-09-28 |
2023-08-13 |
rat |
| Claire Nguyen, Sarah Mondoloni, Tinaïg Le Borgne, Ines Centeno, Maxime Come, Joachim Jehl, Clément Solié, Lauren M Reynolds, Romain Durand-de Cuttoli, Stefania Tolu, Sébastien Valverde, Steve Didienne, Bernadette Hannesse, Jean-François Fiancette, Stéphanie Pons, Uwe Maskos, Véronique Deroche-Gamonet, Deniz Dalkara, Jean-Pierre Hardelin, Alexandre Mourot, Fabio Marti, Philippe Faur. Nicotine inhibits the VTA-to-amygdala dopamine pathway to promote anxiety. Neuron. vol 109. issue 16. 2021-09-02. PMID:34242565. |
nicotine stimulates dopamine (da) neurons of the ventral tegmental area (vta) to establish and maintain reinforcement. |
2021-09-02 |
2023-08-13 |
Not clear |
| Nii A Add. An ongoing saga of nicotine complexity and dopamine heterogeneity: Nicotine activation and inhibition mediating reward and anxiety. Neuron. vol 109. issue 16. 2021-08-25. PMID:34411537. |
an ongoing saga of nicotine complexity and dopamine heterogeneity: nicotine activation and inhibition mediating reward and anxiety. |
2021-08-25 |
2023-08-13 |
Not clear |
| Nii A Add. An ongoing saga of nicotine complexity and dopamine heterogeneity: Nicotine activation and inhibition mediating reward and anxiety. Neuron. vol 109. issue 16. 2021-08-25. PMID:34411537. |
in this issue of neuron, nguyen and colleagues (nguyen et al., 2021) investigate nicotine's effects on diverse midbrain dopamine neurons. |
2021-08-25 |
2023-08-13 |
Not clear |
| Nii A Add. An ongoing saga of nicotine complexity and dopamine heterogeneity: Nicotine activation and inhibition mediating reward and anxiety. Neuron. vol 109. issue 16. 2021-08-25. PMID:34411537. |
their findings provide new understanding of the functional role of ventral tegmental area (vta) dopamine neurons and reveal topographically distinct, pathway-specific, and opposite dopaminergic responses to nicotine that likely mediate reward and anxiety, respectively. |
2021-08-25 |
2023-08-13 |
Not clear |
| Molly A Kwiatkowski, Benjamin Z Roberts, Jordy van Enkhuizen, Baohu Ji, Xianjin Zhou, Jared W Youn. Chronic nicotine, but not suramin or resveratrol, partially remediates the mania-like profile of dopamine transporter knockdown mice. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 42. 2021-08-20. PMID:33191077. |
chronic nicotine, but not suramin or resveratrol, partially remediates the mania-like profile of dopamine transporter knockdown mice. |
2021-08-20 |
2023-08-13 |
mouse |
| Ruthie E Wittenberg, Shannon L Wolfman, Mariella De Biasi, John A Dan. Nicotinic acetylcholine receptors and nicotine addiction: A brief introduction. Neuropharmacology. vol 177. 2021-08-12. PMID:32738308. |
the nachrs that contain the α4 and β2 subunits, often in combination with the α6 subunit, are particularly important for nicotine's ability to increase midbrain dopamine neuron firing rates and phasic burst firing. |
2021-08-12 |
2023-08-13 |
Not clear |