| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Michael Wolter, Thomas Lapointe, Nana Baidoo, Krista A Mitchnick, Cassidy Wideman, Boyer D Winters, Francesco Ler. Double dissociation of perirhinal nicotinic acetylcholine receptors and dopamine D2 receptors in modulation of object memory consolidation by nicotine, cocaine and their conditioned stimuli. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 72. 2023-04-22. PMID:37086715. |
double dissociation of perirhinal nicotinic acetylcholine receptors and dopamine d2 receptors in modulation of object memory consolidation by nicotine, cocaine and their conditioned stimuli. |
2023-04-22 |
2023-08-14 |
rat |
| Michael Wolter, Thomas Lapointe, Nana Baidoo, Krista A Mitchnick, Cassidy Wideman, Boyer D Winters, Francesco Ler. Double dissociation of perirhinal nicotinic acetylcholine receptors and dopamine D2 receptors in modulation of object memory consolidation by nicotine, cocaine and their conditioned stimuli. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology. vol 72. 2023-04-22. PMID:37086715. |
to directly test this hypothesis, a cholinergic nicotinic receptor antagonist (mecamylamine; mec: 0, 10 or 30 µg/side) and a dopamine d2 receptor antagonist (l-741,626: 0, 0.63, 2.5 µg/side) were infused in the perirhinal cortex (prh) to block modulation of object recognition memory consolidation induced by 0.4 mg/kg nicotine, 20 mg/kg cocaine, or their css. |
2023-04-22 |
2023-08-14 |
rat |
| ManHua Zhu, Neil G Rogers, Jasmine V Jahad, Melissa A Herma. Sex differences in the impact of electronic nicotine vapor on corticotropin-releasing factor receptor 1 neurons in the mouse ventral tegmental area. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-03-31. PMID:37001989. |
nicotine engages dopamine neurons in the ventral tegmental area (vta) to encode reward and drive the development of nicotine addiction, however how nicotine alters a stress associated vta population remains unclear. |
2023-03-31 |
2023-08-14 |
mouse |
| Lindsey D McGill, Naze G Avci, Tina Kazemi, Yoshinori Sunaga, Yasemin M Akay, Metin Aka. Prenatal nicotine exposure alters gene expression profiles of neurons in the sub-regions of the VTA during early postnatal development. Scientific reports. vol 13. issue 1. 2023-03-25. PMID:36966190. |
these results suggest that following perinatal nicotine exposure, vta dopamine neurons, especially within the pn sub-region, are significantly excited starting from birth. |
2023-03-25 |
2023-08-14 |
human |
| Xiaoying Tan, Elizabeth M Neslund, Zheng-Ming Din. The involvement of dopamine and D2 receptor-mediated transmission in effects of cotinine in male rats. Neuropharmacology. 2023-03-13. PMID:36914092. |
nac extracellular dopamine levels increased during active self-administration of cotinine and nicotine with less robust increase during cotinine self-administration. |
2023-03-13 |
2023-08-14 |
rat |
| Hillary A Wadsworth, Elizabeth Q Anderson, Benjamin M Williams, Joakim W Ronström, Janna K Moen, Anna M Lee, J Michael McIntosh, Jie Wu, Jordan T Yorgason, Scott C Steffense. Role of α6-Nicotinic Receptors in Alcohol-Induced GABAergic Synaptic Transmission and Plasticity to Cholinergic Interneurons in the Nucleus Accumbens. Molecular neurobiology. 2023-02-21. PMID:36802012. |
the prevailing view is that enhancement of dopamine (da) transmission in the mesolimbic system, consisting of da neurons in the ventral tegmental area (vta) that project to the nucleus accumbens (nac), underlies the reward properties of ethanol (etoh) and nicotine (nic). |
2023-02-21 |
2023-08-14 |
mouse |
| Fatimah Almahasneh, Romany Gerges, Ejlal Abu-El-Rub, Ramada Khasawne. Nicotine abuse and neurodegeneration: Novel pharmacogenetic targets to aid quitting and reduce the risk of dementia. CNS & neurological disorders drug targets. 2023-02-21. PMID:36803746. |
nicotine dependence involves the activation of pleasure response through the stimulation of dopamine release. |
2023-02-21 |
2023-08-14 |
Not clear |
| Brady M Thompson, Matthew E Tracy, Y Wendy Huynh, Linda P Dwoskin, Scott T Barrett, Rick A Bevin. Varenicline serves as the training stimulus in the drug-discriminated goal-tracking task with rats: initial evaluation of potential neuropharmacological processes. Behavioural pharmacology. 2023-02-02. PMID:36730812. |
these rats then received a series of tests with several doses of varenicline, nicotine, nornicotine (a metabolite of nicotine and tobacco alkaloid), sazetidine-a (a partial alpha4beta2 agonist), pha-543613 (an alpha7 agonist), and bupropion (a norepinephrine and dopamine reuptake inhibitor). |
2023-02-02 |
2023-08-14 |
rat |
| Ranjithkumar Chellian, Azin Behnood-Rod, Ryann Wilson, Karen Lin, Grace Wing-Yan King, Adriaan W Bruijnzee. The D1/D2-like receptor antagonist flupentixol and the D2-like receptor antagonist L-741626 decrease operant responding for nicotine and food and locomotor activity in male and female rats. Journal of psychopharmacology (Oxford, England). 2023-01-21. PMID:36680471. |
dopamine plays a role in the reinforcing properties of nicotine, but little is known about the role of dopamine d2-like receptors in nicotine intake and whether there are sex differences in the effects of dopaminergic drugs on nicotine intake. |
2023-01-21 |
2023-08-14 |
rat |
| Lei Fan, Huan Chen, Yong Liu, Hongwei Hou, Qingyuan H. ERK signaling is required for nicotine-induced conditional place preference by regulating neuroplasticity genes expression in male mice. Pharmacology, biochemistry, and behavior. 2022-12-24. PMID:36565790. |
nicotine is an addictive compound that interacts with nicotinic acetylcholine receptors (nachrs) in the ventral tegmental area (vta), inducing a release of dopamine in the nucleus accumbens (nac). |
2022-12-24 |
2023-08-14 |
mouse |
| Guanglin Liu, Ruiyan Wang, Huan Chen, Ping Wu, Yaning Fu, Kaixin Li, Mingda Liu, Zhihao Shi, Yuan Zhang, Yue Su, Lingxiao Song, Hongwei Hou, Qingyuan H. Non-nicotine constituents in cigarette smoke extract enhance nicotine addiction through monoamine oxidase A inhibition. Frontiers in neuroscience. vol 16. 2022-12-12. PMID:36507317. |
individually and in synergy with nicotine were determined by conditioned place preference (cpp), dopamine (da) level detection, the open field test (oft), and the elevated plus maze (epm). |
2022-12-12 |
2023-08-14 |
mouse |
| Brandon J Henderson, Montana R Richardson, Skylar Y Coope. A high-fat diet has sex-specific effects on nicotine vapor self-administration in mice. Drug and alcohol dependence. vol 241. 2022-11-19. PMID:36402049. |
our objective here was to examine if high-fat diet (hfd) impacted nicotine intake and in parallel examine potential changes in dopamine signaling. |
2022-11-19 |
2023-08-14 |
mouse |
| Alice Servonnet, Saleem M Nicol. Dips in dopamine say "no" to nicotine. Neuron. vol 110. issue 18. 2022-09-22. PMID:36137519. |
dips in dopamine say "no" to nicotine. |
2022-09-22 |
2023-08-14 |
Not clear |
| Alice Servonnet, Saleem M Nicol. Dips in dopamine say "no" to nicotine. Neuron. vol 110. issue 18. 2022-09-22. PMID:36137519. |
show that nicotine aversion depends on both desensitization of high-affinity nicotinic acetylcholine receptors (nachrs) that activate midbrain dopamine neurons and activation of low-affinity nachrs that inhibit dopamine neurons via the laterodorsal tegmental nucleus (ldt). |
2022-09-22 |
2023-08-14 |
Not clear |
| Donnie Eddins, Ann Petro, Edward D Levi. Impact of acute nicotine exposure on monoaminergic systems in adolescent and adult male and female rats. Neurotoxicology and teratology. 2022-09-18. PMID:36116700. |
we indexed the effects of acute nicotine ditartrate (0.4 mg/kg, salt weight) administration on dopamine (da) and serotonin (5ht) as well as the da metabolite 3,4-dihydroxyphenylacetic acid (dopac) in several brain regions (nucleus accumbens, striatum and frontal cortex) of 6-week old (adolescent) and 10-week old (young adult) sprague-dawley rats. |
2022-09-18 |
2023-08-14 |
rat |
| Ranjithkumar Chellian, Azin Behnood-Rod, Ryann Wilson, Karen Lin, Grace Wing-Yan King, Marcella Ruppert-Gomez, Alexandria Nicole Teter, Marcelo Febo, Adriaan W Bruijnzee. Dopamine D1-like receptor blockade and stimulation decreases operant responding for nicotine and food in male and female rats. Scientific reports. vol 12. issue 1. 2022-08-19. PMID:35986048. |
dopamine d1-like receptor blockade and stimulation decreases operant responding for nicotine and food in male and female rats. |
2022-08-19 |
2023-08-14 |
rat |
| Ranjithkumar Chellian, Azin Behnood-Rod, Ryann Wilson, Karen Lin, Grace Wing-Yan King, Marcella Ruppert-Gomez, Alexandria Nicole Teter, Marcelo Febo, Adriaan W Bruijnzee. Dopamine D1-like receptor blockade and stimulation decreases operant responding for nicotine and food in male and female rats. Scientific reports. vol 12. issue 1. 2022-08-19. PMID:35986048. |
however, there remains a need for a better understanding of the effects of dopamine d1-like receptor agonists on nicotine intake and the role of sex differences in the effects of dopaminergic drugs on behavior. |
2022-08-19 |
2023-08-14 |
rat |
| Christine Liu, Amanda J Tose, Jeroen P H Verharen, Yichen Zhu, Lilly W Tang, Johannes W de Jong, Jessica X Du, Kevin T Beier, Stephan Lamme. An inhibitory brainstem input to dopamine neurons encodes nicotine aversion. Neuron. 2022-08-03. PMID:35921846. |
an inhibitory brainstem input to dopamine neurons encodes nicotine aversion. |
2022-08-03 |
2023-08-14 |
mouse |
| Christine Liu, Amanda J Tose, Jeroen P H Verharen, Yichen Zhu, Lilly W Tang, Johannes W de Jong, Jessica X Du, Kevin T Beier, Stephan Lamme. An inhibitory brainstem input to dopamine neurons encodes nicotine aversion. Neuron. 2022-08-03. PMID:35921846. |
nicotine stimulates the dopamine (da) system, which is essential for its rewarding effect. |
2022-08-03 |
2023-08-14 |
mouse |
| Zheng Ding, Xiangyu Li, Huan Chen, Hongwei Hou, Qingyuan H. Harmane Potentiates Nicotine Reinforcement Through MAO-A Inhibition at the Dose Related to Cigarette Smoking. Frontiers in molecular neuroscience. vol 15. 2022-07-14. PMID:35832393. |
nicotine is the primary addictive component in cigarette smoke, and dopamine release induced by nicotine is considered a significant cause of persistent smoking and nicotine dependence. |
2022-07-14 |
2023-08-14 |
human |