| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Nisell, G G Nomikos, T H Svensso. Nicotine dependence, midbrain dopamine systems and psychiatric disorders. Pharmacology & toxicology. vol 76. issue 3. 1995-08-24. PMID:7617539. |
the stimulatory action of nicotine on mesolimbic dopamine neurones is exerted both at the somatodendritic and at the terminal levels. |
1995-08-24 |
2023-08-12 |
Not clear |
| M Nisell, G G Nomikos, T H Svensso. Nicotine dependence, midbrain dopamine systems and psychiatric disorders. Pharmacology & toxicology. vol 76. issue 3. 1995-08-24. PMID:7617539. |
yet, the release of dopamine in the nucleus accumbens induced by systemically administered nicotine is abolished by the nicotine receptor antagonist, mecamylamine when administered locally in the ventral tegmental area, but not in the nucleus accumbens. |
1995-08-24 |
2023-08-12 |
Not clear |
| M Nisell, G G Nomikos, T H Svensso. Nicotine dependence, midbrain dopamine systems and psychiatric disorders. Pharmacology & toxicology. vol 76. issue 3. 1995-08-24. PMID:7617539. |
whereas continuous infusion of nicotine into the ventral tegmental area produces a long-lasting increase in accumbal dopamine release, analogously to the effect of systemically administered nicotine, continuous infusion of nicotine into the nucleus accumbens produces a very short-lasting dopamine release. |
1995-08-24 |
2023-08-12 |
Not clear |
| M Nisell, G G Nomikos, T H Svensso. Nicotine dependence, midbrain dopamine systems and psychiatric disorders. Pharmacology & toxicology. vol 76. issue 3. 1995-08-24. PMID:7617539. |
thus, nicotinic receptors in the ventral tegmental area appear to be more significant than those located in the nucleus accumbens for mediating the stimulatory effect of nicotine on dopamine release in the nucleus accumbens. |
1995-08-24 |
2023-08-12 |
Not clear |
| M Nisell, G G Nomikos, T H Svensso. Nicotine dependence, midbrain dopamine systems and psychiatric disorders. Pharmacology & toxicology. vol 76. issue 3. 1995-08-24. PMID:7617539. |
the effect of nicotine on midbrain dopamine systems may help to explain the extremely high prevalence of tobacco-smoking in schizophrenics, who frequently display so-called hypofrontality, i.e. |
1995-08-24 |
2023-08-12 |
Not clear |
| E D Levin, J E Ros. Acute and chronic nicotinic interactions with dopamine systems and working memory performance. Annals of the New York Academy of Sciences. vol 757. 1995-08-15. PMID:7611680. |
nicotine also has significant interactions with dopamine drugs with regard to working memory performance in the radial-arm maze. |
1995-08-15 |
2023-08-12 |
rat |
| D H Johnson, A I Svensson, J A Engel, B Söderpal. Induction but not expression of behavioural sensitization to nicotine in the rat is dependent on glucocorticoids. European journal of pharmacology. vol 276. issue 1-2. 1995-07-18. PMID:7781685. |
provided that hva levels and the dopac/dopamine quotient relatively well reflect the presynaptic dopamine activating effect of nicotine, it may be suggested that corticosteroid-related mechanisms associated with behavioural sensitization to nicotine are post- rather than presynaptically located in relation to mesolimbic dopamine neurons. |
1995-07-18 |
2023-08-12 |
rat |
| J Koistinaho, S M Saga. Light-induced c-fos expression in amacrine cells in the rabbit retina. Brain research. Molecular brain research. vol 29. issue 1. 1995-07-06. PMID:7770001. |
nicotine, kainic acid, nmda and sch 38393, a dopamine d1 receptor agonist, induced fos immunostaining in the inner nuclear and ganglion cell layers, but administration of the corresponding receptor blockers mecamylamine, kynuretic acid, mk-801, haloperidol and sch 23990 did not prevent light-induced fos expression. |
1995-07-06 |
2023-08-12 |
rabbit |
| J F Flood, J F Scherrer, J E Morle. Localized injections of various compounds effecting neurotransmitter activity in the mammillary complex enhance (T-maze) avoidance retention. European journal of pharmacology. vol 275. issue 3. 1995-06-30. PMID:7768289. |
the results indicated that muscarine, nicotine, dopamine, glutamine and adrenoceptor agonists as well as gaba and 5-ht receptor antagonists and neuropeptide y improved retention test performance relative to the control. |
1995-06-30 |
2023-08-12 |
mouse |
| J A Rosecran. The psychopharmacological basis of nicotine's differential effects on behavior: individual subject variability in the rat. Behavior genetics. vol 25. issue 2. 1995-06-01. PMID:7733859. |
however, this does not rule out the role the importance that other biogenic amine systems (i.e., serotonin or dopamine) may have in the genetics of tobacco use or nicotine's variable effects on behavior. |
1995-06-01 |
2023-08-12 |
human |
| C Ksir, G Mellor, C Hart, G A Gerhard. Nicotine enhances dopamine clearance in rat nucleus accumbens. Progress in neuro-psychopharmacology & biological psychiatry. vol 19. issue 1. 1995-05-05. PMID:7708927. |
nicotine enhances dopamine clearance in rat nucleus accumbens. |
1995-05-05 |
2023-08-12 |
rat |
| C Ksir, G Mellor, C Hart, G A Gerhard. Nicotine enhances dopamine clearance in rat nucleus accumbens. Progress in neuro-psychopharmacology & biological psychiatry. vol 19. issue 1. 1995-05-05. PMID:7708927. |
dopamine peak amplitudes decreased following nicotine injection, presumably due to enhanced dopamine reuptake. |
1995-05-05 |
2023-08-12 |
rat |
| M Nisell, G G Nomikos, T H Svensso. Infusion of nicotine in the ventral tegmental area or the nucleus accumbens of the rat differentially affects accumbal dopamine release. Pharmacology & toxicology. vol 75. issue 6. 1995-04-27. PMID:7534921. |
infusion of nicotine in the ventral tegmental area or the nucleus accumbens of the rat differentially affects accumbal dopamine release. |
1995-04-27 |
2023-08-12 |
rat |
| M Nisell, G G Nomikos, T H Svensso. Infusion of nicotine in the ventral tegmental area or the nucleus accumbens of the rat differentially affects accumbal dopamine release. Pharmacology & toxicology. vol 75. issue 6. 1995-04-27. PMID:7534921. |
the present study examined the effects of acute, continuous infusion of nicotine in either the ventral tegmental area or the nucleus accumbens on extracellular concentrations of dopamine in the nucleus accumbens by applying in vivo microdialysis in freely moving rats. |
1995-04-27 |
2023-08-12 |
rat |
| M Nisell, G G Nomikos, T H Svensso. Infusion of nicotine in the ventral tegmental area or the nucleus accumbens of the rat differentially affects accumbal dopamine release. Pharmacology & toxicology. vol 75. issue 6. 1995-04-27. PMID:7534921. |
in the ventral tegmental area produced a long-lasting increase in accumbal dopamine, whereas similar nicotine infusion in the nucleus accumbens increased dopamine levels only within the first 20 min. |
1995-04-27 |
2023-08-12 |
rat |
| M Nisell, G G Nomikos, T H Svensso. Infusion of nicotine in the ventral tegmental area or the nucleus accumbens of the rat differentially affects accumbal dopamine release. Pharmacology & toxicology. vol 75. issue 6. 1995-04-27. PMID:7534921. |
in contrast to the effects of nicotine, n-methyl-d-aspartate infusion in the ventral tegmental area as well as in the nucleus accumbens produced a long-lasting increase in accumbal dopamine levels. |
1995-04-27 |
2023-08-12 |
rat |
| M Nisell, G G Nomikos, T H Svensso. Infusion of nicotine in the ventral tegmental area or the nucleus accumbens of the rat differentially affects accumbal dopamine release. Pharmacology & toxicology. vol 75. issue 6. 1995-04-27. PMID:7534921. |
the more procounced effect of infusion of nicotine in the ventral tegmental area as compared to the nucleus accumbens on accumbal dopamine release may be due to a lower rate or even lack of tolerance to nicotine's stimulatory action in the ventral tegmental area. |
1995-04-27 |
2023-08-12 |
rat |
| H Yamashita, S Kitayama, Y X Zhang, T Takahashi, T Dohi, S Nakamur. Effect of nicotine on dopamine uptake in COS cells possessing the rat dopamine transporter and in PC12 cells. Biochemical pharmacology. vol 49. issue 5. 1995-04-13. PMID:7887991. |
effect of nicotine on dopamine uptake in cos cells possessing the rat dopamine transporter and in pc12 cells. |
1995-04-13 |
2023-08-12 |
rat |
| H Yamashita, S Kitayama, Y X Zhang, T Takahashi, T Dohi, S Nakamur. Effect of nicotine on dopamine uptake in COS cells possessing the rat dopamine transporter and in PC12 cells. Biochemical pharmacology. vol 49. issue 5. 1995-04-13. PMID:7887991. |
the effect of nicotine on the uptake of dopamine (da) is not completely understood. |
1995-04-13 |
2023-08-12 |
rat |
| M E Benwell, D J Balfour, C E Birrel. Desensitization of the nicotine-induced mesolimbic dopamine responses during constant infusion with nicotine. British journal of pharmacology. vol 114. issue 2. 1995-04-10. PMID:7881744. |
desensitization of the nicotine-induced mesolimbic dopamine responses during constant infusion with nicotine. |
1995-04-10 |
2023-08-12 |
rat |