| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| V Bassareo, G Tanda, P Petromilli, C Giua, G Di Chiar. Non-psychostimulant drugs of abuse and anxiogenic drugs activate with differential selectivity dopamine transmission in the nucleus accumbens and in the medial prefrontal cortex of the rat. Psychopharmacology. vol 124. issue 4. 1996-11-25. PMID:8739543. |
systemic administration of low doses of the 5ht3 antagonist ics 205930, previously reported to prevent the increase of extracellular dopamine in the nucleus accumbens elicited by morphine, nicotine, ethanol and haloperidol (carboni et al. |
1996-11-25 |
2023-08-12 |
rat |
| F E Pontieri, G Tanda, F Orzi, G Di Chiar. Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs. Nature. vol 382. issue 6588. 1996-11-13. PMID:8717040. |
here we report that intravenous nicotine in the rat, at doses known to maintain self-administration, stimulates local energy metabolism, as measured by 2-deoxyglucose autoradiography, and dopamine transmission, as estimated by brain microdialysis, in the shell of the nucleus accumbens. |
1996-11-13 |
2023-08-12 |
rat |
| K Pietila, I Laakso, L Ahte. Chronic oral nicotine administration affects the circadian rhythm of dopamine and 5-hydroxytryptamine metabolism in the striata of mice. Naunyn-Schmiedeberg's archives of pharmacology. vol 353. issue 1. 1996-11-06. PMID:8750924. |
chronic oral nicotine administration affects the circadian rhythm of dopamine and 5-hydroxytryptamine metabolism in the striata of mice. |
1996-11-06 |
2023-08-12 |
mouse |
| K Pietila, I Laakso, L Ahte. Chronic oral nicotine administration affects the circadian rhythm of dopamine and 5-hydroxytryptamine metabolism in the striata of mice. Naunyn-Schmiedeberg's archives of pharmacology. vol 353. issue 1. 1996-11-06. PMID:8750924. |
the effect of chronic oral administration of nicotine on the circadian rhythm of striatal dopamine (da) and 5-hydroxytryptamine (5-ht) was studied in mice. |
1996-11-06 |
2023-08-12 |
mouse |
| M R Zarrindast, M Sadegh, B Shafagh. Effects of nicotine on memory retrieval in mice. European journal of pharmacology. vol 295. issue 1. 1996-10-29. PMID:8925865. |
pretreatment with the nicotinic receptor antagonist mecamylamine (0.5-1 mg/kg) decreased, whereas pretreatment with the dopamine d1 receptor antagonist sch 23390 (r-(+)-8-chloro-2,3,4,5-tetrahydro-3-methyl-5-phenyl-1h-3-benzazepine-7-ol maleate) (0.01, 0.05 and 0.1 mg/kg) and the beta-adrenoreceptor antagonist propranolol (10 mg/kg) increased the nicotine response. |
1996-10-29 |
2023-08-12 |
mouse |
| M R Zarrindast, M Sadegh, B Shafagh. Effects of nicotine on memory retrieval in mice. European journal of pharmacology. vol 295. issue 1. 1996-10-29. PMID:8925865. |
the dopamine receptor d2 receptor antagonist sulpiride (5-10 mg/kg), the anti-muscarinic agent atropine (2.5-10 mg/kg), the peripheral nicotinic receptor antagonist hexamethonium (0.01-0.5 mg/kg), the alpha-adrenoceptor antagonist phenoxybenzamine (1 and 10 mg/kg) and the peripheral dopamine d2 receptor antagonist domperidone (5 and 10 mg/kg) did not change the response induced by nicotine. |
1996-10-29 |
2023-08-12 |
mouse |
| M Blum, G Wu, G Mudó, N Belluardo, K Andersson, L F Agnati, K Fux. Chronic continuous infusion of (-)nicotine reduces basic fibroblast growth factor messenger RNA levels in the ventral midbrain of the intact but not of the 6-hydroxydopamine-lesioned rat. Neuroscience. vol 70. issue 1. 1996-10-24. PMID:8848122. |
there is evidence to suggest that this correlation appears to be associated with a neuroprotective role of nicotine for dopamine neurons at least in relation to mechanical injury. |
1996-10-24 |
2023-08-12 |
rat |
| M Blum, G Wu, G Mudó, N Belluardo, K Andersson, L F Agnati, K Fux. Chronic continuous infusion of (-)nicotine reduces basic fibroblast growth factor messenger RNA levels in the ventral midbrain of the intact but not of the 6-hydroxydopamine-lesioned rat. Neuroscience. vol 70. issue 1. 1996-10-24. PMID:8848122. |
however, 1-methyl-4-phenyl-1,2,3,6,-tetrahydropyridine (mptp) neurotoxicity to dopamine neurons is enhanced by chronic continuous (-)nicotine. |
1996-10-24 |
2023-08-12 |
rat |
| M Blum, G Wu, G Mudó, N Belluardo, K Andersson, L F Agnati, K Fux. Chronic continuous infusion of (-)nicotine reduces basic fibroblast growth factor messenger RNA levels in the ventral midbrain of the intact but not of the 6-hydroxydopamine-lesioned rat. Neuroscience. vol 70. issue 1. 1996-10-24. PMID:8848122. |
therefore, it is of interest to explore a possible effect of nicotine on basic fibroblast growth factor expression in the ventral midbrain of intact and 6-hydroxydopamine-lesioned rats and how treatment with nicotine can alter the 6-hydroxydopamine-induced injury of the nigral dopamine nerve cells as evaluated by dopamine biochemistry. |
1996-10-24 |
2023-08-12 |
rat |
| M Blum, G Wu, G Mudó, N Belluardo, K Andersson, L F Agnati, K Fux. Chronic continuous infusion of (-)nicotine reduces basic fibroblast growth factor messenger RNA levels in the ventral midbrain of the intact but not of the 6-hydroxydopamine-lesioned rat. Neuroscience. vol 70. issue 1. 1996-10-24. PMID:8848122. |
in agreement, the 6-hydroxydopamine-induced depletion of dopamine in the neostriatum was unaltered by the nicotine treatment (0.125 mg/kg per h). |
1996-10-24 |
2023-08-12 |
rat |
| K Rasmussen, J F Czachur. Nicotine withdrawal leads to increased firing rates of midbrain dopamine neurons. Neuroreport. vol 7. issue 1. 1996-10-17. PMID:8742482. |
nicotine withdrawal leads to increased firing rates of midbrain dopamine neurons. |
1996-10-17 |
2023-08-12 |
rat |
| K Rasmussen, J F Czachur. Nicotine withdrawal leads to increased firing rates of midbrain dopamine neurons. Neuroreport. vol 7. issue 1. 1996-10-17. PMID:8742482. |
in order to explore the neurophysiology of nicotine withdrawal, we examined the activity of substantia nigra (a9) and ventral tegmental area (a10) dopamine cells in rats undergoing withdrawal from chronic exposure to nicotine. |
1996-10-17 |
2023-08-12 |
rat |
| K Rasmussen, J F Czachur. Nicotine withdrawal leads to increased firing rates of midbrain dopamine neurons. Neuroreport. vol 7. issue 1. 1996-10-17. PMID:8742482. |
chronic administration of nicotine led to a decreased firing rate of a10, but not a9, dopamine cells. |
1996-10-17 |
2023-08-12 |
rat |
| K Rasmussen, J F Czachur. Nicotine withdrawal leads to increased firing rates of midbrain dopamine neurons. Neuroreport. vol 7. issue 1. 1996-10-17. PMID:8742482. |
upon withdrawal from the chronic exposure to nicotine, the firing rates of a10 dopamine cells returned to control levels, while the firing rate of a9 dopamine cells significantly increased above control levels. |
1996-10-17 |
2023-08-12 |
rat |
| K Rasmussen, J F Czachur. Nicotine withdrawal leads to increased firing rates of midbrain dopamine neurons. Neuroreport. vol 7. issue 1. 1996-10-17. PMID:8742482. |
this increased dopamine neuronal activity may play a role in some behavioural symptoms of nicotine withdrawal. |
1996-10-17 |
2023-08-12 |
rat |
| N R Mirza, Q Pei, I P Stolerman, T S Zetterströ. The nicotinic receptor agonists (-)-nicotine and isoarecolone differ in their effects on dopamine release in the nucleus accumbens. European journal of pharmacology. vol 295. issue 2-3. 1996-09-26. PMID:8720585. |
nicotine (0.4 mg/kg s.c.) significantly increased extracellular concentrations of dopamine and of dihydroxyphenylacetic acid (dopac) by 75-80% in nucleus accumbens of rats. |
1996-09-26 |
2023-08-12 |
rat |
| P B Clarke, M Reube. Release of [3H]-noradrenaline from rat hippocampal synaptosomes by nicotine: mediation by different nicotinic receptor subtypes from striatal [3H]-dopamine release. British journal of pharmacology. vol 117. issue 4. 1996-07-24. PMID:8646402. |
nicotine released striatal dopamine more potently than hippocampal na (ec50 0.16 microm vs. 6.5 microm). |
1996-07-24 |
2023-08-12 |
rat |
| P B Clarke, M Reube. Release of [3H]-noradrenaline from rat hippocampal synaptosomes by nicotine: mediation by different nicotinic receptor subtypes from striatal [3H]-dopamine release. British journal of pharmacology. vol 117. issue 4. 1996-07-24. PMID:8646402. |
(+)-anatoxin-a also increased dopamine more potently than na (ec50 0.05 microm vs. 0.39 microm), and maximal effects were similar to those of nicotine. |
1996-07-24 |
2023-08-12 |
rat |
| P B Clarke, M Reube. Release of [3H]-noradrenaline from rat hippocampal synaptosomes by nicotine: mediation by different nicotinic receptor subtypes from striatal [3H]-dopamine release. British journal of pharmacology. vol 117. issue 4. 1996-07-24. PMID:8646402. |
(-)-lobeline (10-320 microm) evoked dopamine release, but the effect was large and delayed with respect to nicotine; na release was not increased but rather depressed at high concentrations of lobeline. |
1996-07-24 |
2023-08-12 |
rat |
| P B Clarke, M Reube. Release of [3H]-noradrenaline from rat hippocampal synaptosomes by nicotine: mediation by different nicotinic receptor subtypes from striatal [3H]-dopamine release. British journal of pharmacology. vol 117. issue 4. 1996-07-24. PMID:8646402. |
the nicotinic antagonist, mecamylamine (10 microm), virtually abolished na and dopamine release evoked by high concentrations of nicotine, ach, cytisine, isoarecolone, and anatoxin-a. |
1996-07-24 |
2023-08-12 |
rat |