| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| D J Balfour, C E Birrell, R J Moran, M E Benwel. Effects of acute D-CPPene on mesoaccumbens dopamine responses to nicotine in the rat. European journal of pharmacology. vol 316. issue 2-3. 1997-06-12. PMID:8982681. |
acute administration of the nmda receptor antagonist, d-cppene (sdz eaa 494; 3-(2-carboxypiperazin-4-yl)-1-propenyl-1-phosphonic acid; 2 mg/kg), abolished (p < 0.01) the sensitised mesoaccumbens dopamine response to nicotine (0.4 mg/kg) measured using in vivo microdialysis, but not the increased locomotor activity, observed in rats pretreated with nicotine prior to the test day. |
1997-06-12 |
2023-08-12 |
rat |
| D J Balfour, C E Birrell, R J Moran, M E Benwel. Effects of acute D-CPPene on mesoaccumbens dopamine responses to nicotine in the rat. European journal of pharmacology. vol 316. issue 2-3. 1997-06-12. PMID:8982681. |
d-cppene enhanced (p < 0.01) the mesoaccumbens dopamine response, but not the locomotor response, to acute nicotine given to drug-naive rats. |
1997-06-12 |
2023-08-12 |
rat |
| D J Balfour, C E Birrell, R J Moran, M E Benwel. Effects of acute D-CPPene on mesoaccumbens dopamine responses to nicotine in the rat. European journal of pharmacology. vol 316. issue 2-3. 1997-06-12. PMID:8982681. |
the data suggest that sensitised mesoaccumbens dopamine responses to nicotine involve co-stimulation of nmda receptors but that this effect is not closely related to sensitisation of the locomotor response to the drug. |
1997-06-12 |
2023-08-12 |
rat |
| G Grigoryan, H Hodges, S Mitchell, J D Sinden, J A Gra. 6-OHDA lesions of the nucleus accumbens accentuate memory deficits in animals with lesions to the forebrain cholinergic projection system: effects of nicotine administration on learning and memory in the water maze. Neurobiology of learning and memory. vol 65. issue 2. 1997-05-30. PMID:8833103. |
effects of nicotine (0.1 mg/kg) were also examined in animals with fcps, n.acc, and combined lesions in order to determine whether facilatory effects of nicotine in fcps lesioned animals are mediated by dopamine release in the n.acc. |
1997-05-30 |
2023-08-12 |
Not clear |
| K Pietilä, O Salminen, T Leikola-Pelho, L Ahte. Tolerance to nicotine's effects on striatal dopamine metabolism in nicotine-withdrawn mice. European journal of pharmacology. vol 318. issue 1. 1997-05-15. PMID:9007507. |
tolerance to nicotine's effects on striatal dopamine metabolism in nicotine-withdrawn mice. |
1997-05-15 |
2023-08-12 |
mouse |
| K Pietilä, O Salminen, T Leikola-Pelho, L Ahte. Tolerance to nicotine's effects on striatal dopamine metabolism in nicotine-withdrawn mice. European journal of pharmacology. vol 318. issue 1. 1997-05-15. PMID:9007507. |
neither withdrawal nor the acute nicotine challenge altered the striatal dopamine concentration. |
1997-05-15 |
2023-08-12 |
mouse |
| K Pietilä, O Salminen, T Leikola-Pelho, L Ahte. Tolerance to nicotine's effects on striatal dopamine metabolism in nicotine-withdrawn mice. European journal of pharmacology. vol 318. issue 1. 1997-05-15. PMID:9007507. |
thus, our results show that tolerance to the acute effects of nicotine on striatal dopamine metabolism can be induced by administering nicotine to mice in the drinking water. |
1997-05-15 |
2023-08-12 |
mouse |
| K Pietilä, O Salminen, T Leikola-Pelho, L Ahte. Tolerance to nicotine's effects on striatal dopamine metabolism in nicotine-withdrawn mice. European journal of pharmacology. vol 318. issue 1. 1997-05-15. PMID:9007507. |
however, neither chronic nicotine treatment nor its withdrawal seem to affect dopamine d1 and d2 receptors in the striatum. |
1997-05-15 |
2023-08-12 |
mouse |
| D L Marshall, P H Redfern, S Wonnacot. Presynaptic nicotinic modulation of dopamine release in the three ascending pathways studied by in vivo microdialysis: comparison of naive and chronic nicotine-treated rats. Journal of neurochemistry. vol 68. issue 4. 1997-04-28. PMID:9084421. |
we have characterised the effect of nicotine, locally applied via a microdialysis probe, on dopamine release from the terminal regions of three ascending dopaminergic pathways in conscious, freely moving rats. |
1997-04-28 |
2023-08-12 |
rat |
| D L Marshall, P H Redfern, S Wonnacot. Presynaptic nicotinic modulation of dopamine release in the three ascending pathways studied by in vivo microdialysis: comparison of naive and chronic nicotine-treated rats. Journal of neurochemistry. vol 68. issue 4. 1997-04-28. PMID:9084421. |
nicotine caused a dose-dependent increase in dopamine release in the striatum, the nucleus accumbens, and, to a lesser extent, the frontal cortex. |
1997-04-28 |
2023-08-12 |
rat |
| M Shoaib, T S Shippenber. Adrenalectomy attenuates nicotine-induced dopamine release and locomotor activity in rats. Psychopharmacology. vol 128. issue 4. 1997-04-16. PMID:8986004. |
nicotine (0.4 mg/kg s.c.) increased extracellular levels of dopamine in the nucleus accumbens. |
1997-04-16 |
2023-08-12 |
mouse |
| M Shoaib, T S Shippenber. Adrenalectomy attenuates nicotine-induced dopamine release and locomotor activity in rats. Psychopharmacology. vol 128. issue 4. 1997-04-16. PMID:8986004. |
however, both adx groups of rats showed smaller increases in dopamine following administration of nicotine. |
1997-04-16 |
2023-08-12 |
mouse |
| L Teng, P A Crooks, P K Sonsalla, L P Dwoski. Lobeline and nicotine evoke [3H]overflow from rat striatal slices preloaded with [3H]dopamine: differential inhibition of synaptosomal and vesicular [3H]dopamine uptake. The Journal of pharmacology and experimental therapeutics. vol 280. issue 3. 1997-04-11. PMID:9067333. |
lobeline and nicotine evoke [3h]overflow from rat striatal slices preloaded with [3h]dopamine: differential inhibition of synaptosomal and vesicular [3h]dopamine uptake. |
1997-04-11 |
2023-08-12 |
rat |
| L Teng, P A Crooks, P K Sonsalla, L P Dwoski. Lobeline and nicotine evoke [3H]overflow from rat striatal slices preloaded with [3H]dopamine: differential inhibition of synaptosomal and vesicular [3H]dopamine uptake. The Journal of pharmacology and experimental therapeutics. vol 280. issue 3. 1997-04-11. PMID:9067333. |
activation of cns dopamine (da) systems results in the reinforcing properties of nicotine. |
1997-04-11 |
2023-08-12 |
rat |
| O Blomqvist, M Ericson, D H Johnson, J A Engel, B Söderpal. Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or subchronic nicotine treatment. European journal of pharmacology. vol 314. issue 3. 1997-04-03. PMID:8957244. |
dopamine release, as indicated by accumulation of 3-methoxytyramine after monoamine oxidase inhibition, was increased in the limbic forebrain (including the nucleus accumbens, the olfactory tubercles, the amygdala and the septum) after acute nicotine (0.35 mg/kg s.c.) or ethanol (2.5 g/kg i.p.) |
1997-04-03 |
2023-08-12 |
rat |
| O Blomqvist, M Ericson, D H Johnson, J A Engel, B Söderpal. Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or subchronic nicotine treatment. European journal of pharmacology. vol 314. issue 3. 1997-04-03. PMID:8957244. |
the present results further implicate central nicotinic receptors in the molecular events mediating the reinforcing properties of ethanol, and suggest that subchronic nicotine enhances the responsiveness of mesolimbic dopamine neurons both to nicotine and to ethanol. |
1997-04-03 |
2023-08-12 |
rat |
| M Riekkinen, L Aroviita, M Kivipelto, K Taskila, P Riekkine. Depletion of serotonin, dopamine and noradrenaline in aged rats decreases the therapeutic effect of nicotine, but not of tetrahydroaminoacridine. European journal of pharmacology. vol 308. issue 3. 1997-03-25. PMID:8858294. |
depletion of serotonin, dopamine and noradrenaline in aged rats decreases the therapeutic effect of nicotine, but not of tetrahydroaminoacridine. |
1997-03-25 |
2023-08-12 |
rat |
| M Riekkinen, L Aroviita, M Kivipelto, K Taskila, P Riekkine. Depletion of serotonin, dopamine and noradrenaline in aged rats decreases the therapeutic effect of nicotine, but not of tetrahydroaminoacridine. European journal of pharmacology. vol 308. issue 3. 1997-03-25. PMID:8858294. |
these results suggest that aged rats are neurochemically more sensitive to p-chlorophenylalanine treatment and that tetrahydroaminoacridine may more effectively than nicotine stimulate spatial learning if 5-ht, dopamine and noradrenaline systems are severely affected. |
1997-03-25 |
2023-08-12 |
rat |
| M Venihaki, A Gravanis, A N Margiori. Comparative study between normal rat chromaffin and PC12 rat pheochromocytoma cells: production and effects of corticotropin-releasing hormone. Endocrinology. vol 138. issue 2. 1997-02-18. PMID:9003004. |
our results are as follows: 1) both types of chromaffin cells contained and secreted comparable amounts of immunoreactive-crh under basal conditions and after k(+)-induced depolarization, nicotine, and interleukin-1 beta; 2) the physicochemical characteristics of the immunoreactive-crh in the cells and the media were identical to the putative crh peptide on both sieve chromatography and rp-hplc; 3) synthetic crh induced the production of catecholamines from both cell types in a dose- and time-dependent manner; this effect was abolished by the antagonist, alpha helical crh; 4) exposure of pc12 cells to ngf (for 1 week) resulted in their neuronal differentiation and the stimulation of their production of crh by 30 times and of dopamine by 10 times, compared with parallel controls; this effect of ngf was abolished by alpha helical crh. |
1997-02-18 |
2023-08-12 |
human |
| C L Martel, J B Mackic, J D Adams, J G McComb, M H Weiss, B V Zlokovi. Transport of dopamine at the blood-brain barrier of the guinea pig: inhibition by psychotropic drugs and nicotine. Pharmaceutical research. vol 13. issue 2. 1997-02-06. PMID:8932451. |
transport of dopamine at the blood-brain barrier of the guinea pig: inhibition by psychotropic drugs and nicotine. |
1997-02-06 |
2023-08-12 |
Not clear |