| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| O Salminen, L Ahte. The effects of acute nicotine on the body temperature and striatal dopamine metabolism of mice during chronic nicotine infusion. Neuroscience letters. vol 284. issue 1-2. 2000-07-03. PMID:10771156. |
on the 7th day of nicotine infusion dopac and hva concentrations were similar to control; and acute nicotine did not increase them suggesting that nicotinic acetylcholine receptors (nachrs) regulating striatal dopamine metabolism were desensitized. |
2000-07-03 |
2023-08-12 |
mouse |
| O Salminen, L Ahte. The effects of acute nicotine on the body temperature and striatal dopamine metabolism of mice during chronic nicotine infusion. Neuroscience letters. vol 284. issue 1-2. 2000-07-03. PMID:10771156. |
the results suggest that the nachrs mediating nicotine's effects on thermoregulation and brain dopamine metabolism differ. |
2000-07-03 |
2023-08-12 |
mouse |
| A J Lança, K L Adamson, K M Coen, B L Chow, W A Corrigal. The pedunculopontine tegmental nucleus and the role of cholinergic neurons in nicotine self-administration in the rat: a correlative neuroanatomical and behavioral study. Neuroscience. vol 96. issue 4. 2000-05-31. PMID:10727791. |
the objective of this study was to determine whether the pedunculopontine tegmental nucleus plays a role in the maintenance of nicotine self-administration, and whether the ascending cholinergic projection from this nucleus to midbrain dopamine neurons in the ventral tegmental area might be involved. |
2000-05-31 |
2023-08-12 |
rat |
| R Yin, E D Frenc. A comparison of the effects of nicotine on dopamine and non-dopamine neurons in the rat ventral tegmental area: an in vitro electrophysiological study. Brain research bulletin. vol 51. issue 6. 2000-05-31. PMID:10758341. |
a comparison of the effects of nicotine on dopamine and non-dopamine neurons in the rat ventral tegmental area: an in vitro electrophysiological study. |
2000-05-31 |
2023-08-12 |
rat |
| R Yin, E D Frenc. A comparison of the effects of nicotine on dopamine and non-dopamine neurons in the rat ventral tegmental area: an in vitro electrophysiological study. Brain research bulletin. vol 51. issue 6. 2000-05-31. PMID:10758341. |
nicotinic acetylcholine receptors on dopamine containing neurons in the ventral tegmental area are thought to be a prime target for nicotine's stimulatory effects. |
2000-05-31 |
2023-08-12 |
rat |
| R Yin, E D Frenc. A comparison of the effects of nicotine on dopamine and non-dopamine neurons in the rat ventral tegmental area: an in vitro electrophysiological study. Brain research bulletin. vol 51. issue 6. 2000-05-31. PMID:10758341. |
however, there is no evidence regarding the actions of nicotine on ventral tegmental gabaergic interneurons which play an important modulatory role in mesolimbic dopamine neuronal excitability. |
2000-05-31 |
2023-08-12 |
rat |
| R Yin, E D Frenc. A comparison of the effects of nicotine on dopamine and non-dopamine neurons in the rat ventral tegmental area: an in vitro electrophysiological study. Brain research bulletin. vol 51. issue 6. 2000-05-31. PMID:10758341. |
in the present study we sought to characterize the effects of nicotine on the activity of both dopamine and non-dopamine neurons in the juvenile rat ventral tegmentum. |
2000-05-31 |
2023-08-12 |
rat |
| R Yin, E D Frenc. A comparison of the effects of nicotine on dopamine and non-dopamine neurons in the rat ventral tegmental area: an in vitro electrophysiological study. Brain research bulletin. vol 51. issue 6. 2000-05-31. PMID:10758341. |
nicotine was found to markedly increase the firing rate of both groups, although the dopamine neuronal response pattern was considerably different and more vigorous than that in the non-dopamine neurons. |
2000-05-31 |
2023-08-12 |
rat |
| R Yin, E D Frenc. A comparison of the effects of nicotine on dopamine and non-dopamine neurons in the rat ventral tegmental area: an in vitro electrophysiological study. Brain research bulletin. vol 51. issue 6. 2000-05-31. PMID:10758341. |
thus, the present results not only confirm that nicotine stimulates the firing rate of ventral tegmental area dopamine neurons, but also that gabaergic neurons may be an important target for nicotine's central nervous system effects. |
2000-05-31 |
2023-08-12 |
rat |
| R Yin, E D Frenc. A comparison of the effects of nicotine on dopamine and non-dopamine neurons in the rat ventral tegmental area: an in vitro electrophysiological study. Brain research bulletin. vol 51. issue 6. 2000-05-31. PMID:10758341. |
the less robust response in the non-dopamine presumptive gabaergic population and their more pronounced desensitization could lead to disinhibition of dopamine neurons thereby facilitating a more sustained increase in the response of mesolimbic dopamine neurons to nicotine. |
2000-05-31 |
2023-08-12 |
rat |
| R J Bainton, L T Tsai, C M Singh, M S Moore, W S Neckameyer, U Heberlei. Dopamine modulates acute responses to cocaine, nicotine and ethanol in Drosophila. Current biology : CB. vol 10. issue 4. 2000-04-25. PMID:10704411. |
dopamine modulates acute responses to cocaine, nicotine and ethanol in drosophila. |
2000-04-25 |
2023-08-12 |
drosophila_melanogaster |
| P Grillner, N Berretta, G Bernardi, T H Svensson, N B Mercur. Muscarinic receptors depress GABAergic synaptic transmission in rat midbrain dopamine neurons. Neuroscience. vol 96. issue 2. 2000-04-20. PMID:10683570. |
the effects of muscarine and nicotine on evoked and spontaneous release of gaba were studied using intracellular and whole-cell patch-clamp recordings from rat midbrain dopamine neurons in an in vitro slice preparation. |
2000-04-20 |
2023-08-12 |
rat |
| J H Johnson, C Zhao, J R James, J A Rosecran. Individual variability of dopamine release from nucleus accumbens induced by nicotine. Brain research bulletin. vol 51. issue 3. 2000-03-30. PMID:10718517. |
individual variability of dopamine release from nucleus accumbens induced by nicotine. |
2000-03-30 |
2023-08-12 |
rat |
| J H Johnson, C Zhao, J R James, J A Rosecran. Individual variability of dopamine release from nucleus accumbens induced by nicotine. Brain research bulletin. vol 51. issue 3. 2000-03-30. PMID:10718517. |
effects of subcutaneous administration of vehicle, amphetamine (1 mg/kg) or nicotine (0.4 mg/kg, injected twice, 90 min apart) on extracellular dopamine (da) concentration in the nucleus accumbens (acc) and ventral tegmental area (vta) of the sprague-dawley rat were studied using microdialysis. |
2000-03-30 |
2023-08-12 |
rat |
| R Pawlak, Y Takada, H Takahashi, T Urano, H Ihara, N Nagai, A Takad. Differential effects of nicotine against stress-induced changes in dopaminergic system in rat striatum and hippocampus. European journal of pharmacology. vol 387. issue 2. 2000-03-28. PMID:10650157. |
since it is well known that nicotine or stress alter the dopaminergic system, we examined the effect of chronic nicotine administration on the dopamine level and its metabolism in the striatum and the hippocampus during stressful conditions in rats. |
2000-03-28 |
2023-08-12 |
rat |
| R Pawlak, Y Takada, H Takahashi, T Urano, H Ihara, N Nagai, A Takad. Differential effects of nicotine against stress-induced changes in dopaminergic system in rat striatum and hippocampus. European journal of pharmacology. vol 387. issue 2. 2000-03-28. PMID:10650157. |
however, stress induced a decrease in dopamine turnover in the hippocampus (p<0.05) but not in the striatum, and nicotine failed to prevent this effect. |
2000-03-28 |
2023-08-12 |
rat |
| R Pawlak, Y Takada, H Takahashi, T Urano, H Ihara, N Nagai, A Takad. Differential effects of nicotine against stress-induced changes in dopaminergic system in rat striatum and hippocampus. European journal of pharmacology. vol 387. issue 2. 2000-03-28. PMID:10650157. |
thus, we demonstrated differential, region- and time-dependent protective effects of chronic nicotine administration against stress-induced changes in dopamine levels and release in brain regions critically affected by stress. |
2000-03-28 |
2023-08-12 |
rat |
| C Cadoni, G Di Chiar. Differential changes in accumbens shell and core dopamine in behavioral sensitization to nicotine. European journal of pharmacology. vol 387. issue 3. 2000-03-28. PMID:10650185. |
differential changes in accumbens shell and core dopamine in behavioral sensitization to nicotine. |
2000-03-28 |
2023-08-12 |
rat |
| C Cadoni, G Di Chiar. Differential changes in accumbens shell and core dopamine in behavioral sensitization to nicotine. European journal of pharmacology. vol 387. issue 3. 2000-03-28. PMID:10650185. |
repeated treatment with nicotine has been shown to sensitize rats to its locomotor stimulant effects and to its properties to stimulate mesolimbic dopamine transmission. |
2000-03-28 |
2023-08-12 |
rat |
| C Cadoni, G Di Chiar. Differential changes in accumbens shell and core dopamine in behavioral sensitization to nicotine. European journal of pharmacology. vol 387. issue 3. 2000-03-28. PMID:10650185. |
we investigated the relationship between sensitization of nicotine induced locomotor stimulation and activation of dopamine transmission in the nucleus accumbens shell and core. |
2000-03-28 |
2023-08-12 |
rat |