| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M E Benwell, D J Balfou. The influence of lobeline on nucleus accumbens dopamine and locomotor responses to nicotine in nicotine-pretreated rats. British journal of pharmacology. vol 125. issue 6. 1999-03-25. PMID:9863636. |
the dopamine responses to nicotine (0.4 mg x kg(-1), s.c.), were abolished (p<0.01) if the nicotine challenge was administered 10 min but not 60 min, after lobeline doses of 4.0 and 10.0 mg kg(-1), i.p., but were unaffected following lobeline at the lowest dose tested (0.7 mg x kg(-1), i.p.) |
1999-03-25 |
2023-08-12 |
rat |
| M E Benwell, D J Balfou. The influence of lobeline on nucleus accumbens dopamine and locomotor responses to nicotine in nicotine-pretreated rats. British journal of pharmacology. vol 125. issue 6. 1999-03-25. PMID:9863636. |
the results suggest that lobeline is a short-acting antagonist of the nicotinic achrs which mediate the effects of nicotine on mesolimbic dopamine activity and locomotor stimulation. |
1999-03-25 |
2023-08-12 |
rat |
| M Louis, P B Clark. Effect of ventral tegmental 6-hydroxydopamine lesions on the locomotor stimulant action of nicotine in rats. Neuropharmacology. vol 37. issue 12. 1999-03-23. PMID:9886673. |
the present results provide further evidence that the locomotor stimulant effect of nicotine is dependent on the integrity of ascending dopamine neurons. |
1999-03-23 |
2023-08-12 |
rat |
| I Sziráki, H Sershen, M Benuck, A Hashim, A Lajth. Receptor systems participating in nicotine-specific effects. Neurochemistry international. vol 33. issue 5. 1999-03-18. PMID:9874095. |
in the present paper we compare the effects of receptor-specific antagonists on the increase of dopamine induced by nicotine with that induced by cocaine in the nucleus accumbens in conscious rats. |
1999-03-18 |
2023-08-12 |
rat |
| I Sziráki, H Sershen, M Benuck, A Hashim, A Lajth. Receptor systems participating in nicotine-specific effects. Neurochemistry international. vol 33. issue 5. 1999-03-18. PMID:9874095. |
when administered together the effect of nicotine and cocaine on the level of dopamine in the accumbens was additive. |
1999-03-18 |
2023-08-12 |
rat |
| I Sziráki, H Sershen, M Benuck, A Hashim, A Lajth. Receptor systems participating in nicotine-specific effects. Neurochemistry international. vol 33. issue 5. 1999-03-18. PMID:9874095. |
the results indicate that there are differences in some of the receptors mediating the central effects of the two compounds examined, nicotine and cocaine, although each influences dopamine levels, and that the two compounds interact. |
1999-03-18 |
2023-08-12 |
rat |
| M Nanri, N Kasahara, J Yamamoto, H Miyake, H Watanab. A comparative study on the effects of nicotine and GTS-21, a new nicotinic agonist, on the locomotor activity and brain monoamine level. Japanese journal of pharmacology. vol 78. issue 3. 1999-03-03. PMID:9869274. |
effects of gts-21 [3-(2,4-dimethoxybenzylidene)-anabaseine dihydrochloride], a selective nicotinic agonist, on locomotor activity and dopamine turnover were examined and compared to those of nicotine to test if gts-21 exhibits side effects similar to those of nicotine. |
1999-03-03 |
2023-08-12 |
mouse |
| C E Birrell, D J Balfou. The influence of nicotine pretreatment on mesoaccumbens dopamine overflow and locomotor responses to D-amphetamine. Psychopharmacology. vol 140. issue 2. 1999-02-25. PMID:9860104. |
the influence of nicotine pretreatment on mesoaccumbens dopamine overflow and locomotor responses to d-amphetamine. |
1999-02-25 |
2023-08-12 |
rat |
| E S Viz. Different temperature dependence of carrier-mediated (cytoplasmic) and stimulus-evoked (exocytotic) release of transmitter: a simple method to separate the two types of release. Neurochemistry international. vol 33. issue 4. 1999-02-10. PMID:9840227. |
the release of [3h]dopamine evoked by a ligand-gated mechanism (nicotine receptor stimulation) was potentiated at low temperature (12 degrees c). |
1999-02-10 |
2023-08-12 |
Not clear |
| R S Mansbach, C C Rovetti, C S Freedlan. The role of monoamine neurotransmitter systems in the nicotine discriminative stimulus. Drug and alcohol dependence. vol 52. issue 2. 1999-02-04. PMID:9800142. |
as a secondary effect of nicotinic stimulation, nicotine elicits an enhanced release of the biogenic amine neurotransmitters dopamine, norepinephrine and serotonin. |
1999-02-04 |
2023-08-12 |
rat |
| R S Mansbach, C C Rovetti, C S Freedlan. The role of monoamine neurotransmitter systems in the nicotine discriminative stimulus. Drug and alcohol dependence. vol 52. issue 2. 1999-02-04. PMID:9800142. |
the non-selective dopamine agonists amphetamine, cocaine and apomorphine produced partial substitution for nicotine, while the selective d2/d3 agonists bromocriptine and 7-oh-dpat and the dopamine autoreceptor antagonist (+)-aj-76 had little effect. |
1999-02-04 |
2023-08-12 |
rat |
| M Shoai. Is dopamine important in nicotine dependence? Journal of physiology, Paris. vol 92. issue 3-4. 1999-01-13. PMID:9789814. |
is dopamine important in nicotine dependence? |
1999-01-13 |
2023-08-12 |
Not clear |
| M Shoai. Is dopamine important in nicotine dependence? Journal of physiology, Paris. vol 92. issue 3-4. 1999-01-13. PMID:9789814. |
this review focuses on three stimulus properties of nicotine and examines the role of dopamine in mediating each effect with respect to d1 and d2 receptor subtypes. |
1999-01-13 |
2023-08-12 |
Not clear |
| M Shoai. Is dopamine important in nicotine dependence? Journal of physiology, Paris. vol 92. issue 3-4. 1999-01-13. PMID:9789814. |
dopamine appears to be critical in mediating the reinforcing effects of nicotine, which is in line with other commonly abused psychomotor stimulants. |
1999-01-13 |
2023-08-12 |
Not clear |
| S D Glick, I M Maisonneuve, K E Visker, K A Fritz, U K Bandarage, M E Kuehn. 18-Methoxycoronardine attenuates nicotine-induced dopamine release and nicotine preferences in rats. Psychopharmacology. vol 139. issue 3. 1998-12-28. PMID:9784085. |
18-methoxycoronardine attenuates nicotine-induced dopamine release and nicotine preferences in rats. |
1998-12-28 |
2023-08-12 |
rat |
| B Ferger, C Spratt, C D Earl, P Teismann, W H Oertel, K Kuschinsk. Effects of nicotine on hydroxyl free radical formation in vitro and on MPTP-induced neurotoxicity in vivo. Naunyn-Schmiedeberg's archives of pharmacology. vol 358. issue 3. 1998-12-22. PMID:9774223. |
high dosage nicotine treatment significantly increased the mptp-induced loss of body weight and resulted in a significantly decreased striatal dopamine content and an increased dopamine turnover in comparison with the mptp-treated controls at day 15. |
1998-12-22 |
2023-08-12 |
mouse |
| B Ferger, C Spratt, C D Earl, P Teismann, W H Oertel, K Kuschinsk. Effects of nicotine on hydroxyl free radical formation in vitro and on MPTP-induced neurotoxicity in vivo. Naunyn-Schmiedeberg's archives of pharmacology. vol 358. issue 3. 1998-12-22. PMID:9774223. |
in vivo experiments with nicotine, however, showed that a low dosage of nicotine did not alleviate the mptp-induced dopamine depletion, but a large dosage even enhanced it. |
1998-12-22 |
2023-08-12 |
mouse |
| Z G Gao, W Y Cui, H T Zhang, C G Li. Effects of nicotine on 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine-induced depression of striatal dopamine content and spontaneous locomotor activity in C57 black mice. Pharmacological research. vol 38. issue 2. 1998-11-20. PMID:9721596. |
effects of nicotine on 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine-induced depression of striatal dopamine content and spontaneous locomotor activity in c57 black mice. |
1998-11-20 |
2023-08-12 |
mouse |
| Z G Gao, W Y Cui, H T Zhang, C G Li. Effects of nicotine on 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine-induced depression of striatal dopamine content and spontaneous locomotor activity in C57 black mice. Pharmacological research. vol 38. issue 2. 1998-11-20. PMID:9721596. |
the present study examined the effects of nicotine on the levels of dopamine and its metabolite 3,4-dihydroxy-phenylacetic acid (dopac) in the striatum and on spontaneous locomotor activity of c57 black mice that had been treated with the neurotoxin 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine (mptp). |
1998-11-20 |
2023-08-12 |
mouse |
| Z G Gao, W Y Cui, H T Zhang, C G Li. Effects of nicotine on 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine-induced depression of striatal dopamine content and spontaneous locomotor activity in C57 black mice. Pharmacological research. vol 38. issue 2. 1998-11-20. PMID:9721596. |
chronic treatment of nicotine (2.0 mg kg-1, s.c., four injections per day) did not influence the striatal content of dopamine and dopac, but it significantly antagonised mptp-induced depression of dopamine. |
1998-11-20 |
2023-08-12 |
mouse |