| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C Cadoni, G Di Chiar. Differential changes in accumbens shell and core dopamine in behavioral sensitization to nicotine. European journal of pharmacology. vol 387. issue 3. 2000-03-28. PMID:10650185. |
rats were administered daily for 5 days with 0.4 mg/kg s.c. of nicotine or with saline and 24 h later, dopamine was monitored by microdialysis in the shell and in the core of nucleus accumbens and behavioral activity was scored after challenge with nicotine (0. |
2000-03-28 |
2023-08-12 |
rat |
| C Cadoni, G Di Chiar. Differential changes in accumbens shell and core dopamine in behavioral sensitization to nicotine. European journal of pharmacology. vol 387. issue 3. 2000-03-28. PMID:10650185. |
behavioral sensitization to nicotine was associated with a reduced response of dopamine transmission in the shell and with an increased one in the core of nucleus accumbens. |
2000-03-28 |
2023-08-12 |
rat |
| E Carboni, L Bortone, C Giua, G Di Chiar. Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats. Drug and alcohol dependence. vol 58. issue 1-2. 2000-03-14. PMID:10669059. |
dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats. |
2000-03-14 |
2023-08-12 |
rat |
| E Carboni, L Bortone, C Giua, G Di Chiar. Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats. Drug and alcohol dependence. vol 58. issue 1-2. 2000-03-14. PMID:10669059. |
the aim of the present study was to investigate the relationship between physical abstinence and changes in dopamine release in the nucleus accumbens and in the medial prefrontal cortex induced by mecamylamine and naloxone in rats chronically exposed to nicotine. |
2000-03-14 |
2023-08-12 |
rat |
| E Carboni, L Bortone, C Giua, G Di Chiar. Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats. Drug and alcohol dependence. vol 58. issue 1-2. 2000-03-14. PMID:10669059. |
steady-state dopamine output from the nucleus accumbens of the rats implanted with nicotine minipumps was higher than that of sham implanted rats; no differences were observed in the prefrontal cortex. |
2000-03-14 |
2023-08-12 |
rat |
| E Carboni, L Bortone, C Giua, G Di Chiar. Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats. Drug and alcohol dependence. vol 58. issue 1-2. 2000-03-14. PMID:10669059. |
in nicotine but not in sham implanted rats mecamylamine (1 mg/kg s.c.) precipitated a physical abstinence syndrome and brought dopamine output back to control values in the nucleus accumbens. |
2000-03-14 |
2023-08-12 |
rat |
| E Carboni, L Bortone, C Giua, G Di Chiar. Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats. Drug and alcohol dependence. vol 58. issue 1-2. 2000-03-14. PMID:10669059. |
in contrast mecamylamine (1 mg/kg s.c.) increased dopamine output in the medial prefrontal cortex of nicotine but not sham-implanted rats. |
2000-03-14 |
2023-08-12 |
rat |
| E Carboni, L Bortone, C Giua, G Di Chiar. Dissociation of physical abstinence signs from changes in extracellular dopamine in the nucleus accumbens and in the prefrontal cortex of nicotine dependent rats. Drug and alcohol dependence. vol 58. issue 1-2. 2000-03-14. PMID:10669059. |
the results indicate that the mesolimbic and mesocortical dopamine system undergo opposite changes during mecamylamine-precipitated abstinence in rats chronically exposed to nicotine and that physical abstinence signs can be dissociated from changes in dopamine transmission. |
2000-03-14 |
2023-08-12 |
rat |
| D Lecca, I Shim, E Costa, J I Javai. Striatal application of nicotine, but not of lobeline, attenuates dopamine release in freely moving rats. Neuropharmacology. vol 39. issue 1. 2000-02-18. PMID:10665822. |
striatal application of nicotine, but not of lobeline, attenuates dopamine release in freely moving rats. |
2000-02-18 |
2023-08-12 |
rat |
| M S Reid, L Fox, L B Ho, S P Berge. Nicotine stimulation of extracellular glutamate levels in the nucleus accumbens: neuropharmacological characterization. Synapse (New York, N.Y.). vol 35. issue 2. 2000-02-17. PMID:10611638. |
in animals previously dopamine denervated by local injections of 6-hydroxydopamine (6-ohda) into the nucleus accumbens, nicotine (0.3 mg/kg, s.c.) stimulation of glutamate levels was enhanced vs. sham-lesioned animals. |
2000-02-17 |
2023-08-12 |
rat |
| J Chen, L He, B Dinger, S Fidon. Stimulus-specific signaling pathways in rabbit carotid body chemoreceptors. Neuroscience. vol 95. issue 1. 2000-01-31. PMID:10619485. |
furthermore, these data correlate with our previous findings which showed that hypoxia, on the one hand, and nicotine on the other, evoke the preferential release of either dopamine or norepinephrine, respectively, from carotid bodies incubated in vitro. |
2000-01-31 |
2023-08-12 |
rabbit |
| G Panagis, B E Hildebrand, T H Svensson, G G Nomiko. Selective c-fos induction and decreased dopamine release in the central nucleus of amygdala in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome. Synapse (New York, N.Y.). vol 35. issue 1. 2000-01-05. PMID:10579804. |
selective c-fos induction and decreased dopamine release in the central nucleus of amygdala in rats displaying a mecamylamine-precipitated nicotine withdrawal syndrome. |
2000-01-05 |
2023-08-12 |
rat |
| O Ghosheh, L P Dwoskin, W K Li, P A Crook. Residence times and half-lives of nicotine metabolites in rat brain after acute peripheral administration of [2'-(14)C]nicotine. Drug metabolism and disposition: the biological fate of chemicals. vol 27. issue 12. 2000-01-04. PMID:10570026. |
even with potential accumulation of cotinine in brain after chronic nicotine administration, it is likely that the brain concentration of cotinine will be insufficient to produce neuropharmacological effects resulting from activation of nicotinic receptors to induce dopamine release. |
2000-01-04 |
2023-08-12 |
rat |
| H S Oliff, K A Gallard. The effect of nicotine on developing brain catecholamine systems. Frontiers in bioscience : a journal and virtual library. vol 4. 1999-12-08. PMID:10577393. |
acute and chronic nicotine administered to pregnant dams causes alterations in dopamine and its metabolites in male and female rat fetuses. |
1999-12-08 |
2023-08-12 |
rat |
| L Serova, E Danailov, F Chamas, E L Sabba. Nicotine infusion modulates immobilization stress-triggered induction of gene expression of rat catecholamine biosynthetic enzymes. The Journal of pharmacology and experimental therapeutics. vol 291. issue 2. 1999-11-24. PMID:10525113. |
multiple injections of nicotine bitartrate (5 mg/kg) elevated mrna levels for the catecholamine biosynthetic enzymes, tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), and phenylethanolamine n-methyltransferase, and of preproneuropeptide y in rat adrenal medulla more than did 1 mg/kg of nicotine bitartrate. |
1999-11-24 |
2023-08-12 |
rat |
| I Sziráki, H Sershen, M Benuck, M Lipovac, A Hashim, T B Cooper, D Allen, A Lajth. The effect of cotinine on nicotine- and cocaine-induced dopamine release in the nucleus accumbens. Neurochemical research. vol 24. issue 11. 1999-11-24. PMID:10555788. |
in studies on conscious, freely-moving rats, intravenous administration of either nicotine or cocaine induced the release of dopamine in the nucleus accumbens, as assayed by microdialysis. |
1999-11-24 |
2023-08-12 |
rat |
| Z J Yang, V Blaha, M M Meguid, A Oler, G Miyat. Infusion of nicotine into the LHA enhances dopamine and 5-HT release and suppresses food intake. Pharmacology, biochemistry, and behavior. vol 64. issue 1. 1999-10-21. PMID:10495010. |
infusion of nicotine into the lha enhances dopamine and 5-ht release and suppresses food intake. |
1999-10-21 |
2023-08-12 |
rat |
| H S Kim, K S Ki. Inhibitory effects of ginseng total saponin on nicotine-induced hyperactivity, reverse tolerance and dopamine receptor supersensitivity. Behavioural brain research. vol 103. issue 1. 1999-10-19. PMID:10475164. |
a repeated administration of nicotine developed reverse tolerance to the ambulation-accelerating activity of nicotine and also developed postsynaptic dopamine (da) receptor supersensitivity. |
1999-10-19 |
2023-08-12 |
mouse |
| B E Hildebrand, G Panagis, T H Svensson, G G Nomiko. Behavioral and biochemical manifestations of mecamylamine-precipitated nicotine withdrawal in the rat: role of nicotinic receptors in the ventral tegmental area. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 21. issue 4. 1999-10-08. PMID:10481840. |
brain mesolimbic dopamine (da) neurons are considered critical for the dependence-producing action of nicotine, and its stimulatory effect on behavior and da neurotransmission appears largely mediated via nicotinic receptors (nachrs) in the ventral tegmental area (vta). |
1999-10-08 |
2023-08-12 |
rat |
| O Salminen, T Seppä, H Gäddnäs, L Ahte. The effects of acute nicotine on the metabolism of dopamine and the expression of Fos protein in striatal and limbic brain areas of rats during chronic nicotine infusion and its withdrawal. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 18. 1999-10-04. PMID:10479714. |
the effects of acute nicotine on the metabolism of dopamine and the expression of fos protein in striatal and limbic brain areas of rats during chronic nicotine infusion and its withdrawal. |
1999-10-04 |
2023-08-12 |
rat |