| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Laurie H L Sellings, Golriz Baharnouri, Lindsey E McQuade, Paul B S Clark. Rewarding and aversive effects of nicotine are segregated within the nucleus accumbens. The European journal of neuroscience. vol 28. issue 2. 2008-10-23. PMID:18702705. |
this controversy is particularly striking in the case of nicotine, with opposing claims that either the rewarding or the aversive effect of nicotine is critically dependent on mesolimbic dopamine transmission. |
2008-10-23 |
2023-08-12 |
rat |
| Kate Cahill, Lindsay F Stead, Tim Lancaste. Nicotine receptor partial agonists for smoking cessation. The Cochrane database of systematic reviews. issue 3. 2008-10-15. PMID:18646137. |
nicotine receptor partial agonists may help people to stop smoking by a combination of maintaining moderate levels of dopamine to counteract withdrawal symptoms (acting as an agonist) and reducing smoking satisfaction (acting as an antagonist). |
2008-10-15 |
2023-08-12 |
Not clear |
| Richard Exley, Michael A Clements, Henrike Hartung, J Michael McIntosh, Stephanie J Crag. Alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 9. 2008-10-08. PMID:18033235. |
alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens. |
2008-10-08 |
2023-08-12 |
mouse |
| Richard Exley, Michael A Clements, Henrike Hartung, J Michael McIntosh, Stephanie J Crag. Alpha6-containing nicotinic acetylcholine receptors dominate the nicotine control of dopamine neurotransmission in nucleus accumbens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 33. issue 9. 2008-10-08. PMID:18033235. |
modulation of striatal dopamine (da) neurotransmission plays a fundamental role in the reinforcing and ultimately addictive effects of nicotine. |
2008-10-08 |
2023-08-12 |
mouse |
| Ramiro Salas, Mariella De Bias. Opposing actions of chronic stress and chronic nicotine on striatal function in mice. Neuroscience letters. vol 440. issue 1. 2008-09-26. PMID:18539390. |
to gain an understanding of the interaction between stress and drug exposure, we studied the effects of concomitant chronic nicotine and chronic stress exposure on mouse striatal dopamine levels. |
2008-09-26 |
2023-08-12 |
mouse |
| Ramiro Salas, Mariella De Bias. Opposing actions of chronic stress and chronic nicotine on striatal function in mice. Neuroscience letters. vol 440. issue 1. 2008-09-26. PMID:18539390. |
therefore, microdialysis was used to measure extracellular dopamine levels in the dorsal striatum of mice chronically treated with nicotine, stress, or both. |
2008-09-26 |
2023-08-12 |
mouse |
| Ramiro Salas, Mariella De Bias. Opposing actions of chronic stress and chronic nicotine on striatal function in mice. Neuroscience letters. vol 440. issue 1. 2008-09-26. PMID:18539390. |
chronic nicotine enhanced nicotine-dependent dopamine release, while chronic stress blunted the response to cocaine. |
2008-09-26 |
2023-08-12 |
mouse |
| Ramiro Salas, Mariella De Bias. Opposing actions of chronic stress and chronic nicotine on striatal function in mice. Neuroscience letters. vol 440. issue 1. 2008-09-26. PMID:18539390. |
when mice were subjected to both chronic nicotine and chronic stress, nicotine- and cocaine-dependent dopamine release was undistinguishable from that of control animals. |
2008-09-26 |
2023-08-12 |
mouse |
| Ramiro Salas, Mariella De Bias. Opposing actions of chronic stress and chronic nicotine on striatal function in mice. Neuroscience letters. vol 440. issue 1. 2008-09-26. PMID:18539390. |
in conclusion, our data suggest that chronic stress and chronic nicotine counteract each other's effect on dopamine release in the striatum. |
2008-09-26 |
2023-08-12 |
mouse |
| Xiomara A Perez, Tanuja Bordia, J Michael McIntosh, Sharon R Grady, Maryka Qui. Long-term nicotine treatment differentially regulates striatal alpha6alpha4beta2* and alpha6(nonalpha4)beta2* nAChR expression and function. Molecular pharmacology. vol 74. issue 3. 2008-09-18. PMID:18583454. |
long-term nicotine treatment via drinking water enhanced nonburst and burst endogenous dopamine release from rat striatal slices. |
2008-09-18 |
2023-08-12 |
mouse |
| Steven R Laviolette, Nicole M Lauzon, Stephanie F Bishop, Ninglei Sun, Huibing Ta. Dopamine signaling through D1-like versus D2-like receptors in the nucleus accumbens core versus shell differentially modulates nicotine reward sensitivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 32. 2008-09-09. PMID:18685027. |
dopamine signaling through d1-like versus d2-like receptors in the nucleus accumbens core versus shell differentially modulates nicotine reward sensitivity. |
2008-09-09 |
2023-08-12 |
Not clear |
| Steven R Laviolette, Nicole M Lauzon, Stephanie F Bishop, Ninglei Sun, Huibing Ta. Dopamine signaling through D1-like versus D2-like receptors in the nucleus accumbens core versus shell differentially modulates nicotine reward sensitivity. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 32. 2008-09-09. PMID:18685027. |
considerable evidence implicates the mesolimbic dopamine (da) system in the processing of nicotine's reinforcing properties, specifically the ventral tegmental area (vta) and the terminal fields of vta daergic projections to the "core" (nacore) and "shell" (nashell) subdivisions of the nucleus accumbens (nac). |
2008-09-09 |
2023-08-12 |
Not clear |
| A H Rezvani, D Eddins, S Slade, D S Hampton, N C Christopher, A Petro, K Horton, M Johnson, E D Levi. Neonatal 6-hydroxydopamine lesions of the frontal cortex in rats: persisting effects on locomotor activity, learning and nicotine self-administration. Neuroscience. vol 154. issue 3. 2008-08-29. PMID:18511204. |
neurochemical studies in adult rats showed that frontal cortical dopamine and dopac levels significantly correlated with nicotine self-administration in the 6-ohda-lesioned animals but not in the controls. |
2008-08-29 |
2023-08-12 |
rat |
| Tanja Vihavainen, Marjo Piltonen, Raimo K Tuominen, Esa R Korpi, Liisa Ahte. Morphine-nicotine interaction in conditioned place preference in mice after chronic nicotine exposure. European journal of pharmacology. vol 587. issue 1-3. 2008-08-25. PMID:18466896. |
previously we found that morphine's effects on locomotor activity and brain dopamine metabolism were enhanced in mice after cessation of 7-week oral nicotine treatment. |
2008-08-25 |
2023-08-12 |
mouse |
| Ryan M Franke, Minjung Park, James D Belluzzi, Frances M Lesli. Prenatal nicotine exposure changes natural and drug-induced reinforcement in adolescent male rats. The European journal of neuroscience. vol 27. issue 11. 2008-08-20. PMID:18588535. |
although dopamine systems that mediate natural and drug-induced reinforcement have been shown in animal studies to be altered by gestational nicotine treatment, it is not clear whether there are concomitant changes in reinforcement sensitivity. |
2008-08-20 |
2023-08-12 |
rat |
| E Shearman, S Fallon, H Sershen, A Lajth. Nicotine-induced monoamine neurotransmitter changes in the brain of young rats. Brain research bulletin. vol 76. issue 6. 2008-08-19. PMID:18598854. |
the small increase of dopamine (da) and more significant increase of serotonin (5-ht) only in the naccs are of significance, and would indicate a more significant role of 5-ht than of da at least in the age difference in nicotine preference. |
2008-08-19 |
2023-08-12 |
rat |
| Linda P Dwoskin, Thomas E Wooters, Sangeetha P Sumithran, Kiran B Siripurapu, B Matthew Joyce, Paul R Lockman, Vamshi K Manda, Joshua T Ayers, Zhenfa Zhang, Agripina G Deaciuc, J Michael McIntosh, Peter A Crooks, Michael T Bard. N,N'-Alkane-diyl-bis-3-picoliniums as nicotinic receptor antagonists: inhibition of nicotine-evoked dopamine release and hyperactivity. The Journal of pharmacology and experimental therapeutics. vol 326. issue 2. 2008-08-12. PMID:18460644. |
the current study evaluated a new series of n,n'-alkane-diyl-bis-3-picolinium (bapi) analogs with c6-c12 methylene linkers as nicotinic acetylcholine receptor (nachr) antagonists, for nicotine-evoked [3h]dopamine (da) overflow, for blood-brain barrier choline transporter affinity, and for attenuation of discriminative stimulus and locomotor stimulant effects of nicotine. |
2008-08-12 |
2023-08-12 |
rat |
| Hidehiko Takahashi, Yota Fujimura, Mika Hayashi, Harumasa Takano, Motoichiro Kato, Yoshiro Okubo, Iwao Kanno, Hiroshi Ito, Tetsuya Suhar. Enhanced dopamine release by nicotine in cigarette smokers: a double-blind, randomized, placebo-controlled pilot study. The international journal of neuropsychopharmacology. vol 11. issue 3. 2008-08-06. PMID:17949514. |
enhanced dopamine release by nicotine in cigarette smokers: a double-blind, randomized, placebo-controlled pilot study. |
2008-08-06 |
2023-08-12 |
Not clear |
| Hidehiko Takahashi, Yota Fujimura, Mika Hayashi, Harumasa Takano, Motoichiro Kato, Yoshiro Okubo, Iwao Kanno, Hiroshi Ito, Tetsuya Suhar. Enhanced dopamine release by nicotine in cigarette smokers: a double-blind, randomized, placebo-controlled pilot study. The international journal of neuropsychopharmacology. vol 11. issue 3. 2008-08-06. PMID:17949514. |
using nicotine gum, we examined the effect of nicotine on dopamine release in smokers and non-smokers and its relation to the degree of nicotine dependence. |
2008-08-06 |
2023-08-12 |
Not clear |
| Hidehiko Takahashi, Yota Fujimura, Mika Hayashi, Harumasa Takano, Motoichiro Kato, Yoshiro Okubo, Iwao Kanno, Hiroshi Ito, Tetsuya Suhar. Enhanced dopamine release by nicotine in cigarette smokers: a double-blind, randomized, placebo-controlled pilot study. The international journal of neuropsychopharmacology. vol 11. issue 3. 2008-08-06. PMID:17949514. |
the bpnd difference might reflect enhanced dopamine release in smokers and the reinforced effect of nicotine. |
2008-08-06 |
2023-08-12 |
Not clear |