| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Miriam Melis, Giuliano Pillolla, Antonio Luchicchi, Anna Lisa Muntoni, Sevil Yasar, Steven R Goldberg, Marco Pisti. Endogenous fatty acid ethanolamides suppress nicotine-induced activation of mesolimbic dopamine neurons through nuclear receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 51. 2009-01-12. PMID:19091987. |
nicotine stimulates the activity of mesolimbic dopamine neurons, which is believed to mediate the rewarding and addictive properties of tobacco use. |
2009-01-12 |
2023-08-12 |
Not clear |
| Miriam Melis, Giuliano Pillolla, Antonio Luchicchi, Anna Lisa Muntoni, Sevil Yasar, Steven R Goldberg, Marco Pisti. Endogenous fatty acid ethanolamides suppress nicotine-induced activation of mesolimbic dopamine neurons through nuclear receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 28. issue 51. 2009-01-12. PMID:19091987. |
here, we investigated the modulation of nicotine effects by the endocannabinoid system on dopamine neurons in the ventral tegmental area with electrophysiological techniques in vivo and in vitro. |
2009-01-12 |
2023-08-12 |
Not clear |
| Yanqi Liang, Mona Boules, Amanda M Shaw, Katrina Williams, Paul Fredrickson, Elliott Richelso. Effect of a novel neurotensin analog, NT69L, on nicotine-induced alterations in monoamine levels in rat brain. Brain research. vol 1231. 2009-01-07. PMID:18687313. |
acute or chronic (0.4 mg/kg, sc, once daily for 2 weeks) administration of nicotine elicited increases in extracellular levels of dopamine, dopamine metabolites, norepinephrine, or serotonin in medial prefrontal cortex, nucleus accumbens shell, and core of rats. |
2009-01-07 |
2023-08-12 |
rat |
| Yanqi Liang, Mona Boules, Amanda M Shaw, Katrina Williams, Paul Fredrickson, Elliott Richelso. Effect of a novel neurotensin analog, NT69L, on nicotine-induced alterations in monoamine levels in rat brain. Brain research. vol 1231. 2009-01-07. PMID:18687313. |
pretreatment with nt69l (1 mg/kg, intraperitoneally, ip) administered 40 min before nicotine injection significantly attenuated the acute nicotine-evoked increases in norepinephrine levels in medial prefrontal cortex, dopamine and serotonin in nucleus accumbens shell. |
2009-01-07 |
2023-08-12 |
rat |
| Yanqi Liang, Mona Boules, Amanda M Shaw, Katrina Williams, Paul Fredrickson, Elliott Richelso. Effect of a novel neurotensin analog, NT69L, on nicotine-induced alterations in monoamine levels in rat brain. Brain research. vol 1231. 2009-01-07. PMID:18687313. |
after chronic nicotine administration, pretreatment of nt69l markedly reversed the increase in dopamine levels in the nucleus accumbens core. |
2009-01-07 |
2023-08-12 |
rat |
| Kenneth A Perkins, Caryn Lerman, Sarah Coddington, Christopher Jetton, Joshua L Karelitz, Annette Wilson, J Richard Jennings, Robert Ferrell, Andrew W Bergen, Neal L Benowit. Gene and gene by sex associations with initial sensitivity to nicotine in nonsmokers. Behavioural pharmacology. vol 19. issue 5-6. 2008-12-31. PMID:18690117. |
for the dopamine d4 receptor [drd4 variable number of tandem repeats (vntr)], presence of the 7-repeat allele was associated with greater aversive responses to nicotine (decreases in 'vigor', positive affect, and rapid information processing; increased cortisol) and reduced nicotine choice. |
2008-12-31 |
2023-08-12 |
Not clear |
| Kenneth A Perkins, Caryn Lerman, Sarah Coddington, Christopher Jetton, Joshua L Karelitz, Annette Wilson, J Richard Jennings, Robert Ferrell, Andrew W Bergen, Neal L Benowit. Gene and gene by sex associations with initial sensitivity to nicotine in nonsmokers. Behavioural pharmacology. vol 19. issue 5-6. 2008-12-31. PMID:18690117. |
although these results are preliminary, this study is the first to suggest that genetic polymorphisms related to function in the dopamine d4, and perhaps d2, receptor may modulate initial sensitivity to nicotine before the onset of dependence and may do so differentially between men and women. |
2008-12-31 |
2023-08-12 |
Not clear |
| Kenneth A Perkins, Caryn Lerman, Amy Grottenthaler, Melinda M Ciccocioppo, Melissa Milanak, Cynthia A Conklin, Andrew W Bergen, Neal L Benowit. Dopamine and opioid gene variants are associated with increased smoking reward and reinforcement owing to negative mood. Behavioural pharmacology. vol 19. issue 5-6. 2008-12-31. PMID:18690118. |
we explored associations of gene variants in the dopamine, opioid, and serotonin pathways with smoking reward ('liking') and reinforcement (latency to first puff and total puffs) as a function of negative mood and expected versus actual nicotine content of the cigarette. |
2008-12-31 |
2023-08-12 |
Not clear |
| Kenneth A Perkins, Caryn Lerman, Amy Grottenthaler, Melinda M Ciccocioppo, Melissa Milanak, Cynthia A Conklin, Andrew W Bergen, Neal L Benowit. Dopamine and opioid gene variants are associated with increased smoking reward and reinforcement owing to negative mood. Behavioural pharmacology. vol 19. issue 5-6. 2008-12-31. PMID:18690118. |
the increase in smoking amount owing to negative mood was associated with: dopamine d2 receptor (drd2) c957t (cc>tt or ct), slc6a3 (presence of 9 repeat>absence of 9), and among those given a nicotine cigarette, drd4 (presence of 7 repeat>absence of 7) and drd2/ankk1 taqia (tt or ct>cc). |
2008-12-31 |
2023-08-12 |
Not clear |
| Tanja Vihavainen, Toni R A Relander, Riikka Leiviskä, Mikko Airavaara, Raimo K Tuominen, Liisa Ahtee, Timo Petteri Pieppone. Chronic nicotine modifies the effects of morphine on extracellular striatal dopamine and ventral tegmental GABA. Journal of neurochemistry. vol 107. issue 3. 2008-12-16. PMID:18786163. |
chronic nicotine modifies the effects of morphine on extracellular striatal dopamine and ventral tegmental gaba. |
2008-12-16 |
2023-08-12 |
mouse |
| Tanja Vihavainen, Toni R A Relander, Riikka Leiviskä, Mikko Airavaara, Raimo K Tuominen, Liisa Ahtee, Timo Petteri Pieppone. Chronic nicotine modifies the effects of morphine on extracellular striatal dopamine and ventral tegmental GABA. Journal of neurochemistry. vol 107. issue 3. 2008-12-16. PMID:18786163. |
chronic nicotine treatment did not change basal extracellular concentrations of dopamine and its metabolites in the caudate putamen and nucleus accumbens, nor did it affect the rate of dopamine synthesis, as assessed by 3-hydroxybenzylhydrazine dihydrochloride-induced dopa accumulation. |
2008-12-16 |
2023-08-12 |
mouse |
| Taro Kishi, Masashi Ikeda, Tsuyoshi Kitajima, Yoshio Yamanouchi, Yoko Kinoshita, Kunihiro Kawashima, Toshiya Inada, Mutsuo Harano, Tokutaro Komiyama, Toru Hori, Mitsuhiko Yamada, Masaomi Iyo, Ichiro Sora, Yoshimoto Sekine, Norio Ozaki, Hiroshi Ujike, Nakao Iwat. Alpha4 and beta2 subunits of neuronal nicotinic acetylcholine receptor genes are not associated with methamphetamine-use disorder in the Japanese population. Annals of the New York Academy of Sciences. vol 1139. 2008-12-09. PMID:18991851. |
the mesolimbic system is thought to be involved in the reinforcing action of many addictive drugs and the release of dopamine modulated by neuronal nicotine cholinergic receptors (nachrs). |
2008-12-09 |
2023-08-12 |
Not clear |
| Weihua Huang, Thomas J Payne, Jennie Z Ma, Ming D L. A functional polymorphism, rs6280, in DRD3 is significantly associated with nicotine dependence in European-American smokers. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. vol 147B. issue 7. 2008-11-17. PMID:18348205. |
the genes encoding dopamine receptors are thus plausible candidates for involvement in nicotine dependence (nd). |
2008-11-17 |
2023-08-12 |
human |
| Athina Marko. Review. Neurobiology of nicotine dependence. Philosophical transactions of the Royal Society of London. Series B, Biological sciences. vol 363. issue 1507. 2008-11-17. PMID:18640919. |
preclinical research in animal models of the various aspects of nicotine dependence suggests a critical role of glutamate, gamma-aminobutyric acid (gaba), cholinergic and dopamine neurotransmitter interactions in the ventral tegmental area and possibly other brain sites, such as the central nucleus of the amygdala and the prefrontal cortex, in the effects of nicotine. |
2008-11-17 |
2023-08-12 |
Not clear |
| Neal Innocent, Phil D Livingstone, Arik Hone, Atsuko Kimura, Tracey Young, Paul Whiteaker, J Michael McIntosh, Susan Wonnacot. Alpha-conotoxin Arenatus IB[V11L,V16D] [corrected] is a potent and selective antagonist at rat and human native alpha7 nicotinic acetylcholine receptors. The Journal of pharmacology and experimental therapeutics. vol 327. issue 2. 2008-11-13. PMID:18664588. |
rat brain alpha7 nachrs contribute to dopamine release from striatal minces; alpha-ctxarib[v11l,v16d] (300 nm) selectively inhibited choline-evoked dopamine release without affecting responses evoked by nicotine that activates heteromeric nachrs. |
2008-11-13 |
2023-08-12 |
human |
| Kelli R Rodvelt, Todd R Schachtman, George R Kracke, Dennis K Mille. NMDA receptor blockade augmented nicotine-evoked dopamine release from rat prefrontal cortex slices. Neuroscience letters. vol 440. issue 3. 2008-11-05. PMID:18579301. |
nicotine evokes dopamine release through activation of nicotinic acetylcholine receptors, and tobacco cigarette smoking is more prevalent among individuals diagnosed with schizophrenia. |
2008-11-05 |
2023-08-12 |
rat |
| Kelli R Rodvelt, Todd R Schachtman, George R Kracke, Dennis K Mille. NMDA receptor blockade augmented nicotine-evoked dopamine release from rat prefrontal cortex slices. Neuroscience letters. vol 440. issue 3. 2008-11-05. PMID:18579301. |
the effect of the nmda receptor antagonist, ketamine, on the effect of nicotine in rat prefrontal cortex was examined using a slice superfusion assay in which cortical slices were preloaded with [(3)h] dopamine. |
2008-11-05 |
2023-08-12 |
rat |
| Kelli R Rodvelt, Todd R Schachtman, George R Kracke, Dennis K Mille. NMDA receptor blockade augmented nicotine-evoked dopamine release from rat prefrontal cortex slices. Neuroscience letters. vol 440. issue 3. 2008-11-05. PMID:18579301. |
this indicates that nmda receptor blockade increased the potency and efficacy of nicotine to evoke dopamine release from prefrontal cortex slices, suggesting that ketamine induced hypersensitivity to nicotine. |
2008-11-05 |
2023-08-12 |
rat |
| D Parolaro, T Rubin. The role of the endogenous cannabinoid system in drug addiction. Drug news & perspectives. vol 21. issue 3. 2008-11-03. PMID:18560613. |
for a long time, dopamine has been consistently associated with the reinforcing effects of most drugs of abuse but, recently, pharmacological evidence points to the possibility that pharmacological management of the endocannabinoid system might not only block the direct reinforcing effect of cannabis, opioids, nicotine and ethanol, but also prevent the relapse to various drugs of abuse including opioids, cocaine, nicotine, alcohol and amphetamine. |
2008-11-03 |
2023-08-12 |
Not clear |
| J Andrés Abin-Carriquiry, Gustavo Costa, Jessika Urbanavicius, Bruce K Cassels, Marco Rebolledo-Fuentes, Susan Wonnacott, Federico Daja. In vivo modulation of dopaminergic nigrostriatal pathways by cytisine derivatives: implications for Parkinson's Disease. European journal of pharmacology. vol 589. issue 1-3. 2008-10-24. PMID:18589414. |
cytisine, 5-bromocytisine and nicotine were much more efficacious than 3-bromocytisine in eliciting dopamine release in response to their local application through the microdialysis probe. |
2008-10-24 |
2023-08-12 |
Not clear |