| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Edward F Domino, Hideo Tsukad. Nicotine sensitization of monkey striatal dopamine release. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19232339. |
1) does acute nicotine preferentially release more dopamine in the striatum than in the prefrontal cortex? |
2009-07-07 |
2023-08-12 |
human |
| Edward F Domino, Hideo Tsukad. Nicotine sensitization of monkey striatal dopamine release. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19232339. |
2) do repeated doses of nicotine produce sensitization of striatal dopamine release? |
2009-07-07 |
2023-08-12 |
human |
| Edward F Domino, Hideo Tsukad. Nicotine sensitization of monkey striatal dopamine release. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19232339. |
dopamine release was measured after overnight nicotine abstinence using the i.v. |
2009-07-07 |
2023-08-12 |
human |
| Edward F Domino, Hideo Tsukad. Nicotine sensitization of monkey striatal dopamine release. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19232339. |
with a lowered baseline, a greater facilitation of dopamine release was produced by nicotine compared to that obtained under control conditions when the baseline was higher. |
2009-07-07 |
2023-08-12 |
human |
| Edward F Domino, Hideo Tsukad. Nicotine sensitization of monkey striatal dopamine release. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19232339. |
the impaired dopamine release with overnight nicotine abstinence was transiently enhanced in a dose dependent manner. |
2009-07-07 |
2023-08-12 |
human |
| Edward F Domino, Hideo Tsukad. Nicotine sensitization of monkey striatal dopamine release. European journal of pharmacology. vol 607. issue 1-3. 2009-07-07. PMID:19232339. |
these data regarding the striatum are consistent with previous findings in rodents of nicotine sensitization of dopamine release especially in nucleus accumbens following repeated administration. |
2009-07-07 |
2023-08-12 |
human |
| Nibedita Naha, Hae Young Lee, Jin Su Hwang, Jong Yoon Bahk, Moon Seok Park, Sang Yeol Lee, Sung Hoon Kim, Myeong Ok Ki. Nicotine tolerance to PC12 cell line: acute and chronic exposures modulate dopamine D2 receptor and tyrosine hydroxylase expression. Neurological research. vol 31. issue 3. 2009-07-07. PMID:19406037. |
nicotine tolerance to pc12 cell line: acute and chronic exposures modulate dopamine d2 receptor and tyrosine hydroxylase expression. |
2009-07-07 |
2023-08-12 |
rat |
| Nibedita Naha, Hae Young Lee, Jin Su Hwang, Jong Yoon Bahk, Moon Seok Park, Sang Yeol Lee, Sung Hoon Kim, Myeong Ok Ki. Nicotine tolerance to PC12 cell line: acute and chronic exposures modulate dopamine D2 receptor and tyrosine hydroxylase expression. Neurological research. vol 31. issue 3. 2009-07-07. PMID:19406037. |
pc12 is a clonal cell line from chromaffin tumor of rat adrenal pheochromocytoma that releases catecholamine including dopamine, which via interaction with its receptor (d(1) and d(2) receptor), is known to be involved in reward and reinforcement properties of many addictive drugs like nicotine. |
2009-07-07 |
2023-08-12 |
rat |
| Nibedita Naha, Hae Young Lee, Jin Su Hwang, Jong Yoon Bahk, Moon Seok Park, Sang Yeol Lee, Sung Hoon Kim, Myeong Ok Ki. Nicotine tolerance to PC12 cell line: acute and chronic exposures modulate dopamine D2 receptor and tyrosine hydroxylase expression. Neurological research. vol 31. issue 3. 2009-07-07. PMID:19406037. |
however, nicotine tolerance on dopamine receptors in pc12 cell line is poorly understood. |
2009-07-07 |
2023-08-12 |
rat |
| Nibedita Naha, Hae Young Lee, Jin Su Hwang, Jong Yoon Bahk, Moon Seok Park, Sang Yeol Lee, Sung Hoon Kim, Myeong Ok Ki. Nicotine tolerance to PC12 cell line: acute and chronic exposures modulate dopamine D2 receptor and tyrosine hydroxylase expression. Neurological research. vol 31. issue 3. 2009-07-07. PMID:19406037. |
in this paper, we have demonstrated the tolerance to acute and chronic nicotine administrations on pc12 cell line on the basis of the expressions of dopamine receptors and tyrosine hydroxylase, the rate-limiting enzyme of dopamine biosynthesis, by western blot, immunohistochemistry and in situ hybridization. |
2009-07-07 |
2023-08-12 |
rat |
| Nibedita Naha, Hae Young Lee, Jin Su Hwang, Jong Yoon Bahk, Moon Seok Park, Sang Yeol Lee, Sung Hoon Kim, Myeong Ok Ki. Nicotine tolerance to PC12 cell line: acute and chronic exposures modulate dopamine D2 receptor and tyrosine hydroxylase expression. Neurological research. vol 31. issue 3. 2009-07-07. PMID:19406037. |
in vitro treatment of nicotine resulted in similar expressional changes of dopamine d(2) receptor and tyrosine hydroxylase at protein and mrna levels in dose- and time-dependent manner, whereas dopamine d(1) receptor did not reveal any positive output. |
2009-07-07 |
2023-08-12 |
rat |
| Nibedita Naha, Hae Young Lee, Jin Su Hwang, Jong Yoon Bahk, Moon Seok Park, Sang Yeol Lee, Sung Hoon Kim, Myeong Ok Ki. Nicotine tolerance to PC12 cell line: acute and chronic exposures modulate dopamine D2 receptor and tyrosine hydroxylase expression. Neurological research. vol 31. issue 3. 2009-07-07. PMID:19406037. |
therefore, this study implied a new approach towards nicotine tolerance which is likely to be related to the modulation of dopamine d(2) receptor and tyrosine hydroxylase expressions by chronic and acute nicotine exposures in pc12 cell line. |
2009-07-07 |
2023-08-12 |
rat |
| C Wernicke, J Reese, A Kraschewski, G Winterer, H Rommelspacher, J Gallina. Distinct haplogenotypes of the dopamine D2 receptor gene are associated with non-smoking behaviour and daily cigarette consumption. Pharmacopsychiatry. vol 42. issue 2. 2009-06-25. PMID:19308877. |
dopamine systems in the cns are decisively implicated in the motivational and rewarding properties of nicotine. |
2009-06-25 |
2023-08-12 |
human |
| Xun Tang, Song Guo, Hongqiang Sun, Xuemei Song, Zuonin Jiang, Lixiang Sheng, Dongfeng Zhou, Yonghua Hu, Dafang Che. Gene-gene interactions of CYP2A6 and MAOA polymorphisms on smoking behavior in Chinese male population. Pharmacogenetics and genomics. vol 19. issue 5. 2009-06-17. PMID:19415821. |
consequently, genetic polymorphisms in both nicotine metabolism and dopamine catabolism genes may influence smoking behavior, and interact with each other resulting in risk modulation. |
2009-06-17 |
2023-08-12 |
Not clear |
| Pheona M Radcliffe, Carol R Sterling, A William Tan. Induction of tyrosine hydroxylase mRNA by nicotine in rat midbrain is inhibited by mifepristone. Journal of neurochemistry. vol 109. issue 5. 2009-06-15. PMID:19476543. |
our results are consistent with the hypothesis that nicotine induces th mrna in midbrain by elevating glucocorticoids, which then act on glucocorticoid receptors in dopamine neurons leading to transcriptional activation of the th gene. |
2009-06-15 |
2023-08-12 |
mouse |
| Phil D Livingstone, Jayaraman Srinivasan, James N C Kew, Lee A Dawson, Cecilia Gotti, Milena Moretti, Mohammed Shoaib, Susan Wonnacot. alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate dopamine release in vitro and in vivo in the rat prefrontal cortex. The European journal of neuroscience. vol 29. issue 3. 2009-06-12. PMID:19187266. |
nicotine enhances attentional and working memory aspects of executive function in the prefrontal cortex (pfc) where dopamine plays a major role. |
2009-06-12 |
2023-08-12 |
rat |
| Phil D Livingstone, Jayaraman Srinivasan, James N C Kew, Lee A Dawson, Cecilia Gotti, Milena Moretti, Mohammed Shoaib, Susan Wonnacot. alpha7 and non-alpha7 nicotinic acetylcholine receptors modulate dopamine release in vitro and in vivo in the rat prefrontal cortex. The European journal of neuroscience. vol 29. issue 3. 2009-06-12. PMID:19187266. |
nicotine and 5-iodo-a-85380 (beta2* selective) elicited [(3)h]dopamine release from both pfc and striatal prisms in vitro and dopamine overflow from medial pfc in vivo. |
2009-06-12 |
2023-08-12 |
rat |
| Luping Z Huang, Neeraja Parameswaran, Tanuja Bordia, J Michael McIntosh, Maryka Qui. Nicotine is neuroprotective when administered before but not after nigrostriatal damage in rats and monkeys. Journal of neurochemistry. vol 109. issue 3. 2009-06-09. PMID:19250334. |
nicotine pre-treatment attenuated behavioral deficits and lessened lesion-induced losses of the striatal dopamine transporter, and alpha6beta2* and alpha4beta2* nicotinic receptors (nachrs). |
2009-06-09 |
2023-08-12 |
rat |
| Weihua Huang, Ming D L. Differential allelic expression of dopamine D1 receptor gene (DRD1) is modulated by microRNA miR-504. Biological psychiatry. vol 65. issue 8. 2009-05-19. PMID:19135651. |
previously, we reported that dopamine d1 receptor gene (drd1) is associated with nicotine dependence (nd) and demonstrated that two alleles (a and g) of polymorphism rs686 in the 3'-untranslated region (3'utr) of drd1 are expressed differentially. |
2009-05-19 |
2023-08-12 |
Not clear |
| Elmar H Pinkhardt, Jan Kassubek, Dagmar Brummer, Michael Koelch, Albert C Ludolph, Joerg M Fegert, Andrea G Ludolp. Intensified testing for attention-deficit hyperactivity disorder (ADHD) in girls should reduce depression and smoking in adult females and the prevalence of ADHD in the longterm. Medical hypotheses. vol 72. issue 4. 2009-05-04. PMID:19128887. |
since nicotine indirectly enhances the intrasynaptic dopamine level which presumably is too low both in adhd and in depression, smoking might be used as a self-medication in women with untreated adhd and consecutive depression. |
2009-05-04 |
2023-08-12 |
human |