| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Brigitte Schmid, Dorothea Blomeyer, Katja Becker, Jens Treutlein, Ulrich S Zimmermann, Arlette F Buchmann, Martin H Schmidt, Günter Esser, Tobias Banaschewski, Marcella Rietschel, Manfred Lauch. The interaction between the dopamine transporter gene and age at onset in relation to tobacco and alcohol use among 19-year-olds. Addiction biology. vol 14. issue 4. 2010-03-10. PMID:19740369. |
recent evidence suggests that heterogeneity in the age at onset could explain the inconsistent findings of association studies relating the dopamine transporter (dat1) gene with alcohol and nicotine consumption. |
2010-03-10 |
2023-08-12 |
Not clear |
| Luis A Natividad, Hugo A Tejeda, Oscar V Torres, Laura E O'Del. Nicotine withdrawal produces a decrease in extracellular levels of dopamine in the nucleus accumbens that is lower in adolescent versus adult male rats. Synapse (New York, N.Y.). vol 64. issue 2. 2010-03-01. PMID:19771590. |
nicotine withdrawal produces a decrease in extracellular levels of dopamine in the nucleus accumbens that is lower in adolescent versus adult male rats. |
2010-03-01 |
2023-08-12 |
rat |
| Luis A Natividad, Hugo A Tejeda, Oscar V Torres, Laura E O'Del. Nicotine withdrawal produces a decrease in extracellular levels of dopamine in the nucleus accumbens that is lower in adolescent versus adult male rats. Synapse (New York, N.Y.). vol 64. issue 2. 2010-03-01. PMID:19771590. |
this study compared dopamine levels in the nacc of male adolescent and adult rats experiencing nicotine withdrawal. |
2010-03-01 |
2023-08-12 |
rat |
| Luis A Natividad, Hugo A Tejeda, Oscar V Torres, Laura E O'Del. Nicotine withdrawal produces a decrease in extracellular levels of dopamine in the nucleus accumbens that is lower in adolescent versus adult male rats. Synapse (New York, N.Y.). vol 64. issue 2. 2010-03-01. PMID:19771590. |
these results provide a potential mechanism involving dopamine that mediates developmental differences in nicotine withdrawal. |
2010-03-01 |
2023-08-12 |
rat |
| P Vieyra-Reyes, A Venebra-Muñoz, B Rivas-Santiago, F García-Garcí. [Nicotine as an antidepressant and regulator of sleep in subjects with depression]. Revista de neurologia. vol 49. issue 12. 2010-02-05. PMID:20013719. |
taking into account these observations it will be explained how nicotine possibly acts in relation to two main neurotransmitters: serotonin and dopamine; and as a neuroprotective agent under a depressive condition. |
2010-02-05 |
2023-08-12 |
human |
| Kazuhiko Iwahashi, Jun Aok. A review of smoking behavior and smokers evidence (chemical modification, inducing nicotine metabolism, and individual variations by genotype: dopaminergic function and personality traits). Drug and chemical toxicology. vol 32. issue 4. 2010-01-15. PMID:19793020. |
the nicotine metabolism of cyp2a6 (cyp2a6*1a,*1b, and *1c), and the cholecystokinin (cck; which modulates the release of dopamine) and cck-a receptor gene and personality traits for neo-ffi, was investigated for the mechanism for elucidation of the smoking behavior in japanese populations. |
2010-01-15 |
2023-08-12 |
human |
| M L Gregório, E C Wietzikoski, M M Ferro, J L M Silveira, M A B F Vital, C Da Cunh. Nicotine induces sensitization of turning behavior in 6-hydroxydopamine lesioned rats. Neurotoxicity research. vol 15. issue 4. 2010-01-11. PMID:19384569. |
testing this hypothesis is important because nicotine has been shown to present neuroprotective and acute symptomatic effects on pd, but few studies have addressed the question of whether it may induce long-lasting effects on dopamine neurotransmission. |
2010-01-11 |
2023-08-12 |
rat |
| M L Gregório, E C Wietzikoski, M M Ferro, J L M Silveira, M A B F Vital, C Da Cunh. Nicotine induces sensitization of turning behavior in 6-hydroxydopamine lesioned rats. Neurotoxicity research. vol 15. issue 4. 2010-01-11. PMID:19384569. |
this result suggests that, like amphetamine, nicotine induces turning behavior by promoting release of dopamine in the non-lesioned striatum of the rats. |
2010-01-11 |
2023-08-12 |
rat |
| M L Gregório, E C Wietzikoski, M M Ferro, J L M Silveira, M A B F Vital, C Da Cunh. Nicotine induces sensitization of turning behavior in 6-hydroxydopamine lesioned rats. Neurotoxicity research. vol 15. issue 4. 2010-01-11. PMID:19384569. |
first, the dopamine amount that could be released in the lesioned hemi-striatum by the nicotine pretreatment was minimum-less than 3%, as detected by hplc-ec. |
2010-01-11 |
2023-08-12 |
rat |
| M L Gregório, E C Wietzikoski, M M Ferro, J L M Silveira, M A B F Vital, C Da Cunh. Nicotine induces sensitization of turning behavior in 6-hydroxydopamine lesioned rats. Neurotoxicity research. vol 15. issue 4. 2010-01-11. PMID:19384569. |
therefore, it is unlikely that the sensitization of the turning behavior induced by nicotine was consequent of the release of dopamine. |
2010-01-11 |
2023-08-12 |
rat |
| Christina Gianoulaki. Endogenous opioids and addiction to alcohol and other drugs of abuse. Current topics in medicinal chemistry. vol 9. issue 11. 2010-01-11. PMID:19747123. |
it has also been shown that regardless of their initial site of action many drugs of abuse, such as morphine, nicotine, cocaine, alcohol and amphetamines, induce an increase in the extracellular concentration of dopamine in the nucleus accumbens. |
2010-01-11 |
2023-08-12 |
Not clear |
| Ju Wang, Jong-Man Kim, David M Donovan, Kevin G Becker, Ming D L. Significant modulation of mitochondrial electron transport system by nicotine in various rat brain regions. Mitochondrion. vol 9. issue 3. 2010-01-07. PMID:19460297. |
in this study, using a microarray consisting of 4793 clones derived from a mouse dopamine cdna library, we profiled the gene expression patterns for six brain regions (amygdala, hippocampus, nucleus accumbens, prefrontal cortex, striatum and ventral tegmental area) of female sprague-dawley rats subjected to nicotine treatment for 7days through osmotic minipump infusion. |
2010-01-07 |
2023-08-12 |
mouse |
| F Ivy Carroll, Bruce E Blough, Philip Abraham, Andrew C Mills, J Ashley Holleman, Scott A Wolckenhauer, Ann M Decker, Antonio Landavazo, K Timothy McElroy, Hernán A Navarro, Michael B Gatch, Michael J Forste. Synthesis and biological evaluation of bupropion analogues as potential pharmacotherapies for cocaine addiction. Journal of medicinal chemistry. vol 52. issue 21. 2009-12-15. PMID:19821577. |
2-(n-cyclopropylamino)-3-chloropropiophenone (1x) had the most favorable in vitro efficacy and in vivo pharmacological profile for an indirect dopamine agonist pharmacotherapy for treating cocaine, methamphetamine, nicotine, and other drugs of abuse addiction. |
2009-12-15 |
2023-08-12 |
Not clear |
| Cristina Cadoni, Tiziana Muto, Gaetano Di Chiar. Nicotine differentially affects dopamine transmission in the nucleus accumbens shell and core of Lewis and Fischer 344 rats. Neuropharmacology. vol 57. issue 5-6. 2009-12-04. PMID:19647004. |
nicotine differentially affects dopamine transmission in the nucleus accumbens shell and core of lewis and fischer 344 rats. |
2009-12-04 |
2023-08-12 |
rat |
| Cristina Cadoni, Tiziana Muto, Gaetano Di Chiar. Nicotine differentially affects dopamine transmission in the nucleus accumbens shell and core of Lewis and Fischer 344 rats. Neuropharmacology. vol 57. issue 5-6. 2009-12-04. PMID:19647004. |
in order to clarify the mechanisms of these differences we investigated, by means of dual probe microdialysis, the effect of different doses of nicotine (0.05, 0.1, 0.2, 0.4 mg/kg s.c.) on dopamine transmission in the shell and in the core of nucleus accumbens. |
2009-12-04 |
2023-08-12 |
rat |
| Cristina Cadoni, Tiziana Muto, Gaetano Di Chiar. Nicotine differentially affects dopamine transmission in the nucleus accumbens shell and core of Lewis and Fischer 344 rats. Neuropharmacology. vol 57. issue 5-6. 2009-12-04. PMID:19647004. |
while no differences were observed between strains in dopamine basal values, lewis rats, compared to fischer 344 ones, showed in general a larger increase of da transmission following nicotine both in the shell and in the core of the nucleus accumbens. |
2009-12-04 |
2023-08-12 |
rat |
| Cristina Cadoni, Tiziana Muto, Gaetano Di Chiar. Nicotine differentially affects dopamine transmission in the nucleus accumbens shell and core of Lewis and Fischer 344 rats. Neuropharmacology. vol 57. issue 5-6. 2009-12-04. PMID:19647004. |
these results suggest that strain-related differences in the sensitivity of mesolimbic dopamine transmission to nicotine might be involved in the reported differences in the reinforcing effect of nicotine in lewis and fischer 344 rats. |
2009-12-04 |
2023-08-12 |
rat |
| Eszter Kótyuk, Réka Kovács-Nagy, Gabor Faludi, Róbert Urbán, Zsolt Rónai, Maria Sasvári-Székely, Anna Székel. [Association between nicotine dependence and the -521 promoter polymorfism of the dopamine D4 receptor in patients with major depression]. Neuropsychopharmacologia Hungarica : a Magyar Pszichofarmakologiai Egyesulet lapja = official journal of the Hungarian Association of Psychopharmacology. vol 11. issue 2. 2009-11-04. PMID:19827313. |
[association between nicotine dependence and the -521 promoter polymorfism of the dopamine d4 receptor in patients with major depression]. |
2009-11-04 |
2023-08-12 |
Not clear |
| Andrew W Bergen, David V Conti, David Van Den Berg, Wonho Lee, Jinghua Liu, Dalin Li, Nan Guo, Huaiyu Mi, Paul D Thomas, Christina N Lessov-Schlaggar, Ruth Krasnow, Yungang He, Denise Nishita, Ruhong Jiang, Jennifer B McClure, Elizabeth Tildesley, Hyman Hops, Rachel F Tyndale, Neal L Benowitz, Caryn Lerman, Gary E Swa. Dopamine genes and nicotine dependence in treatment-seeking and community smokers. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 34. issue 10. 2009-10-29. PMID:19494806. |
dopamine genes and nicotine dependence in treatment-seeking and community smokers. |
2009-10-29 |
2023-08-12 |
Not clear |
| N Naha, S P Li, B C Yang, T J Park, M O Ki. Time-dependent exposure of nicotine and smoke modulate ultrasubcellular organelle localization of dopamine D1 and D2 receptors in the rat caudate-putamen. Synapse (New York, N.Y.). vol 63. issue 10. 2009-10-26. PMID:19562699. |
time-dependent exposure of nicotine and smoke modulate ultrasubcellular organelle localization of dopamine d1 and d2 receptors in the rat caudate-putamen. |
2009-10-26 |
2023-08-12 |
rat |