| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Gopalakrishnan, E J Molinari, J P Sulliva. Regulation of human alpha4beta2 neuronal nicotinic acetylcholine receptors by cholinergic channel ligands and second messenger pathways. Molecular pharmacology. vol 52. issue 3. 1997-10-02. PMID:9281615. |
the alpha4beta2 nicotinic acetylcholine receptors (nachrs), a major subtype in the brain, have been shown to be modulated by chronic treatment with nicotine. |
1997-10-02 |
2023-08-12 |
human |
| S L Chao, T J Dennehy, J E Casid. Whitefly (Hemiptera: Aleyrodidae) binding site for imidacloprid and related insecticides: a putative nicotinic acetylcholine receptor. Journal of economic entomology. vol 90. issue 4. 1997-09-12. PMID:9260539. |
the pharmacological profile of the binding site (examined with imidacloprid and the analogs listed above, and nicotine, alpha-bungarotoxin, carbachol, acetylcholine [with paraoxon], and atropine) is consistent with that anticipated for a nicotinic acetylcholine receptor and correlates well with binding results for house fly, musca domestica l., head membranes under the same conditions. |
1997-09-12 |
2023-08-12 |
Not clear |
| J Koley, A K Basak, M Das, S Sinha, B Kole. Rectal response of cardiac origin in the cat: involvement of nitric oxide and acetylcholine. European journal of pharmacology. vol 325. issue 2-3. 1997-08-04. PMID:9163565. |
from these observations it is clear that the relaxation phase of the rectal response to coronary occlusion or epicardial nicotine is mediated through neither cholinergic nor adrenergic pathways but through the release of nitric oxide whereas the contraction phase of such a cardio-rectal response is mediated through the release of the neurotransmitter, acetylcholine. |
1997-08-04 |
2023-08-12 |
cat |
| S J Heishman, D J Balfour, N L Benowitz, D K Hatsukami, J M Lindstrom, J K Ocken. Society for Research on Nicotine and Tobacco. Addiction (Abingdon, England). vol 92. issue 5. 1997-07-24. PMID:9219386. |
data were presented describing our current understanding of the structure and function of neuronal nicotinic acetylcholine receptors, by which nicotine exerts most, if not all, of its effects in the brain. |
1997-07-24 |
2023-08-12 |
Not clear |
| M Haass, W Küble. Nicotine and sympathetic neurotransmission. Cardiovascular drugs and therapy. vol 10. issue 6. 1997-07-02. PMID:9110108. |
these nicotine-induced cardiovascular effects are mainly due to stimulation of sympathetic neurotransmission, as nicotine stimulates catecholamine release by an activation of nicotine acetylcholine receptors localized on peripheral postganglionic sympathetic nerve endings and the adrenal medulla. |
1997-07-02 |
2023-08-12 |
human |
| H Laskowska-Bozek, U Bany, T Burakowski, R Janiak, B Lewartowski, J Ryzewsk. Effect of cholinergic stimulation on free intracellular Ca2+ concentration in human lymphocytes. Neuroimmunomodulation. vol 3. issue 4. 1997-06-27. PMID:9094447. |
the aim of this work was to measure changes in calcium concentration in cytosol of lymphocytes stimulated with acetylcholine agonists - carbachol (analogue of acetylcholine) or nicotine. |
1997-06-27 |
2023-08-12 |
human |
| W G Mayhan, K P Pate. Effect of nicotine on endothelium-dependent arteriolar dilatation in vivo. The American journal of physiology. vol 272. issue 5 Pt 2. 1997-06-27. PMID:9176303. |
we measured the diameter of resistance arterioles (approximately 50 microns in diameter) contained within the microcirculation of the hamster cheek pouch in response to endothelium-dependent (acetylcholine and adp) and -independent (nitroglycerin) agonists before and after an intravenous infusion of vehicle or two concentrations of nicotine. |
1997-06-27 |
2023-08-12 |
Not clear |
| X Peng, V Gerzanich, R Anand, F Wang, J Lindstro. Chronic nicotine treatment up-regulates alpha3 and alpha7 acetylcholine receptor subtypes expressed by the human neuroblastoma cell line SH-SY5Y. Molecular pharmacology. vol 51. issue 5. 1997-06-05. PMID:9145915. |
chronic exposure to nicotine has been reported to increase the number of nicotinic acetylcholine receptors (achrs) in brain. |
1997-06-05 |
2023-08-12 |
human |
| N M Grzywacz, J S Tootle, F R Amtho. Is the input to a GABAergic or cholinergic synapse the sole asymmetry in rabbit's retinal directional selectivity? Visual neuroscience. vol 14. issue 1. 1997-05-19. PMID:9057267. |
in a extension of a masland and ames (1976) experiment, saturating concentrations of antagonists blocked the effects of exogenous acetylcholine or nicotine applied during synaptic blockade. |
1997-05-19 |
2023-08-12 |
rabbit |
| R K Freund, M R Palme. Ethanol depression of cerebellar Purkinje neuron firing involves nicotinic acetylcholine receptors. Experimental neurology. vol 143. issue 2. 1997-04-07. PMID:9056394. |
since there is evidence from other studies indicating that nicotine may interact with etoh responses, in this study we investigated whether nicotinic acetylcholine receptors (nachr's) might be also involved in etoh-induced depressions of these neurons in urethane-anesthetized sprague-dawley rats. |
1997-04-07 |
2023-08-12 |
rat |
| W M Fu, J J Li. Regulation of acetylcholine release by presynaptic nicotinic receptors at developing neuromuscular synapses. Molecular pharmacology. vol 51. issue 3. 1997-03-28. PMID:9058593. |
however, nicotine markedly increased the ssc frequency in the presence of low concentrations of glutamate (2 microm) or atp (0.15 mm) or high k+ (8 mm), which only slightly increased the frequency of spontaneous acetylcholine (ach) secretion. |
1997-03-28 |
2023-08-12 |
xenopus_laevis |
| A Campos-Caro, J C Rovira, F Vicente-Agulló, J J Ballesta, S Sala, M Criado, F Sal. Role of the putative transmembrane segment M3 in gating of neuronal nicotinic receptors. Biochemistry. vol 36. issue 9. 1997-03-26. PMID:9054579. |
substitution of the m3 transmembrane segment in the alpha7 subunit modifies the kinetic properties of the chimeric achrs as follows: (a) a 6-fold reduction in the maximal current evoked by nicotinic agonists, (b) a 10-fold decrease in the macroscopic desensitization rate, (c) an increase of almost 1 order of magnitude in the apparent affinity for acetylcholine and nicotine, and (d) a decrease in the affinity for alpha-bungarotoxin. |
1997-03-26 |
2023-08-12 |
xenopus_laevis |
| M J Wayner, D L Armstrong, C F Pheli. Nicotine blocks angiotensin II inhibition of LTP in the dentate gyrus. Peptides. vol 17. issue 7. 1997-03-14. PMID:8959746. |
nicotine acetylcholine receptors are found in the hippocampus and nicotine is involved in the enhancement of complex and important psychological functions that are mediated by the hippocampus; therefore, the possibility that nicotine prevents the ang ii inhibition of dentate granule cell ltp was examined. |
1997-03-14 |
2023-08-12 |
Not clear |
| I Pintér, G B Makara, Z Ac. Acetylcholine stimulates growth hormone secretion in the neonatal rat pituitary. Journal of neuroendocrinology. vol 8. issue 12. 1997-03-07. PMID:8953472. |
m1 muscarinic agonist mcn a343 mimicked the gh releasing effect of acetylcholine, nicotine was ineffective. |
1997-03-07 |
2023-08-12 |
rat |
| T M Brotz, A Bors. Cholinergic and GABAergic receptors on fly tangential cells and their role in visual motion detection. Journal of neurophysiology. vol 76. issue 3. 1997-02-20. PMID:8890292. |
iontophoretic application of acetylcholine, carbachol, and nicotine depolarizes vs and hs cells. |
1997-02-20 |
2023-08-12 |
Not clear |
| L E Chavez-Noriega, J H Crona, M S Washburn, A Urrutia, K J Elliott, E C Johnso. Pharmacological characterization of recombinant human neuronal nicotinic acetylcholine receptors h alpha 2 beta 2, h alpha 2 beta 4, h alpha 3 beta 2, h alpha 3 beta 4, h alpha 4 beta 2, h alpha 4 beta 4 and h alpha 7 expressed in Xenopus oocytes. The Journal of pharmacology and experimental therapeutics. vol 280. issue 1. 1997-02-10. PMID:8996215. |
human neuronal nicotinic acetylcholine receptors (nachrs) h alpha 2 beta 2, h alpha 2 beta 4, h alpha 3 beta 2, h alpha 3 beta 4, h alpha 4 beta 2, h alpha 4 beta 4 and h alpha 7 were expressed in xenopus oocytes and tested for their sensitivities to the nicotinic agonists acetylcholine (ach), nicotine, cytisine (cyt) and 1,1-dimethyl-4-phenylpiperazinium (dmpp) and the nachr. |
1997-02-10 |
2023-08-12 |
human |
| A I Sacaan, R T Reid, E M Santori, P Adams, L D Correa, L S Mahaffy, L Bleicher, N D Cosford, K A Stauderman, I A McDonald, T S Rao, G K Lloy. Pharmacological characterization of SIB-1765F: a novel cholinergic ion channel agonist. The Journal of pharmacology and experimental therapeutics. vol 280. issue 1. 1997-02-10. PMID:8996218. |
nicotine, the prototypical agonist for neuronal nicotinic acetylcholine receptors (nachr), nonselectively activates nachr limiting its use in elucidating the function of nachr subtypes. |
1997-02-10 |
2023-08-12 |
human |
| B M Paddle, M H Dowlin. Blockade of cardiac nicotinic responses by anticholinesterases. General pharmacology. vol 27. issue 5. 1997-01-30. PMID:8842691. |
tacrine (10 microm) and physostigmine (10 microm) completely inhibited the positive chronotropic and inotropic actions of acetylcholine (ach) or nicotine in the atropinized guinea pig right atria. |
1997-01-30 |
2023-08-12 |
Not clear |
| P Jäkälä, M Björklund, P Riekkine. Suppression of neocortical high-voltage spindles by nicotinic acetylcholine and 5-HT2 receptor stimulation. European journal of pharmacology. vol 299. issue 1-3. 1997-01-23. PMID:8901007. |
the results suggest that nicotinic acetylcholine and 5-ht2 receptors may act in concert to suppress neocortical high-voltage spindling in rats, and that intact brain serotonergic systems may be important for some of the therapeutic effects of nicotine. |
1997-01-23 |
2023-08-12 |
rat |
| C Chen, C LeBlanc, R P Bobbi. Differences in cholinergic responses from outer hair cells of rat and guinea pig. Hearing research. vol 98. issue 1-2. 1997-01-21. PMID:8880176. |
a cholinergic receptor on outer hair cells (ohc) in guinea pig cochlea induces a k+ current when it is activated by acetylcholine and suberyldicholine but not by nicotine or muscarine (bobbin, 1995). |
1997-01-21 |
2023-08-12 |
rat |