| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M Yamamoto, S Usuda, S Tachikawa, H Maen. Pharmacological studies on a new benzamide derivative, YM-09151-2, with potential neuroleptic properties. Neuropharmacology. vol 21. issue 10. 1983-01-19. PMID:6128690. |
however, ym-09151-2 was less effective than haloperidol and chlorpromazine in both augmenting the spindle bursts produced by electrical stimulation of the caudate nucleus and antagonizing the inhibitory effect of l-dopa on the caudate spindle, indicating a smaller effect of ym-09151-2 on the extrapyramidal dopaminergic system than that of the two neuroleptic drugs. |
1983-01-19 |
2023-08-12 |
cat |
| P Pollak, J M Gaio, M Hommel, J Pellat, J Perret, R Chatea. [Modification of extrapyramidal signs by apomorphine associated with various dopaminergic antagonists]. Revue neurologique. vol 138. issue 5. 1983-01-19. PMID:7146725. |
an acute administration of various doses of apomorphine, a dopaminergic agonist, and of dopaminergic receptor blockers (domperidone, sulpiride, haloperidol), was double-blindly achieved in a parkinsonian patient also suffering from dyskinesia. |
1983-01-19 |
2023-08-12 |
Not clear |
| A Kuruvilla, Y K Fung, N J Uretsk. BehavioraL and biochemical changes caused by muscimol in mice withdrawN from haloperidol administration. Neuropharmacology. vol 21. issue 9. 1983-01-07. PMID:6890637. |
these results indicate that after chronic haloperidol administration there is not only an enhanced response to dopaminergic agonists but also to gabaergic agonists. |
1983-01-07 |
2023-08-12 |
mouse |
| M C de Mello, A L Ventura, R Paes de Carvalho, W L Klein, F G de Mell. Regulation of dopamine- and adenosine-dependent adenylate cyclase systems of chicken embryo retina cells in culture. Proceedings of the National Academy of Sciences of the United States of America. vol 79. issue 18. 1982-12-21. PMID:6291061. |
this spontaneous desensitization appeared to be caused by functional dopaminergic transmission because it could be blocked by the dopamine antagonist haloperidol. |
1982-12-21 |
2023-08-12 |
chicken |
| S D Glic. Operant control of turning in circles: a new model of dopaminergic drug action. Brain research. vol 245. issue 2. 1982-12-21. PMID:6889903. |
the effects of d-amphetamine, apomorphine, haloperidol and methohexital could be readily dissociated indicating that the operant rotation paradigm could likely become a useful behavioral assay of dopaminergic drug action. |
1982-12-21 |
2023-08-12 |
rat |
| M A Cheĭdo, G V Idova, L V Devoĭn. [Distribution of functionally differing cells in immunocompetent organs on haloperidol administration]. Biulleten' eksperimental'noi biologii i meditsiny. vol 94. issue 8. 1982-12-21. PMID:6982083. |
haloperidol blockade of the dopaminergic system entails redistribution of functionally different cells. |
1982-12-21 |
2023-08-12 |
Not clear |
| Y Uchida, T Nomot. Effect of intracerebroventricular administration of chlorpromazine on the serum level of free fatty acids in rats. Japanese journal of pharmacology. vol 32. issue 4. 1982-12-18. PMID:6813546. |
the dopaminergic blocking agent haloperidol caused a rapid decrease in serum ffa. |
1982-12-18 |
2023-08-12 |
rat |
| N J Smatresk, S Lahir. Aortic body chemoreceptor responses to dopamine, haloperidol, and pargyline. Journal of applied physiology: respiratory, environmental and exercise physiology. vol 53. issue 3. 1982-12-18. PMID:7129979. |
aortic chemoreceptor activity, from single- or few-fiber afferent nerve preparations, was measured in response to dopamine and a dopaminergic blocker, haloperidol, in 18 anesthetized cats. |
1982-12-18 |
2023-08-12 |
Not clear |
| E Schrumpf, P Linnesta. Effect of cholinergic, adrenergic, and dopaminergic blockade on gastrin secretion in healthy subjects. Scandinavian journal of gastroenterology. vol 17. issue 1. 1982-12-16. PMID:6127788. |
it is suggested that this effect of haloperidol is mediated by blockade of dopaminergic receptors, supporting the idea that the dopaminergic nervous system may influence gastrin secretion. |
1982-12-16 |
2023-08-12 |
human |
| M Itoh, B L Furman, J E Geric. Dopaminergic suppression of pancreatic somatostatin secretion. Acta endocrinologica. vol 101. issue 1. 1982-12-03. PMID:6126981. |
maximum suppression of irs and iri release was evident at 20 micro m dopamine with half-maximal suppression occurring at 0.5-1 micro m. maximal stimulation of irg release was observed at 100 micro m dopamine with a half-maximal response occurring at 5-10 micro m. suppression of irs secretion by dopamine (20 micro m) was completely reversed by the dopaminergic antagonists haloperidol (5 micro m) and pimozide (5 micro m) but was only partially reversed by the alpha adrenergic antagonist phentolamine (2 micro m), and was further suppressed by the beta adrenergic antagonist phentolamine (2 micro m). |
1982-12-03 |
2023-08-12 |
rat |
| C X Poulos, R Hinso. Pavlovian conditional tolerance to haloperidol catalepsy: evidence of dynamic adaptation in the dopaminergic system. Science (New York, N.Y.). vol 218. issue 4571. 1982-12-03. PMID:6889765. |
pavlovian conditional tolerance to haloperidol catalepsy: evidence of dynamic adaptation in the dopaminergic system. |
1982-12-03 |
2023-08-12 |
rat |
| N Vaysse, J Laval, C Senarens, J P Esteve, A Ribe. Dopamine-stimulated cyclic AMP and binding of [3H] dopamine in acini from dog pancreas. Biochimica et biophysica acta. vol 720. issue 4. 1982-12-02. PMID:6180776. |
cyclic amp accumulation caused by dopamine was detected at 1.10(-8) m and was half-maximal at 7.9 +/- 3.4 10(-7) m. the increase at 1.10(-5) m, (7.5-fold) was equal to the half-maximal increase caused by secretin at 1.10(-9) m. haloperidol, a dopaminergic receptor antagonist inhibited cyclic amp accumulation caused by dopamine. |
1982-12-02 |
2023-08-12 |
dog |
| H Takeuchi, S J Young, P M Grove. Dopaminergic terminal excitability following arrival of the nerve impulse: the influence of amphetamine and haloperidol. Brain research. vol 245. issue 1. 1982-12-02. PMID:6288195. |
dopaminergic terminal excitability following arrival of the nerve impulse: the influence of amphetamine and haloperidol. |
1982-12-02 |
2023-08-12 |
rat |
| H Takeuchi, S J Young, P M Grove. Dopaminergic terminal excitability following arrival of the nerve impulse: the influence of amphetamine and haloperidol. Brain research. vol 245. issue 1. 1982-12-02. PMID:6288195. |
haloperidol, a dopamine antagonist, increased the excitability of dopaminergic terminal fields, an effect which was also more marked earlier in the phasic interval. |
1982-12-02 |
2023-08-12 |
rat |
| H Takeuchi, S J Young, P M Grove. Dopaminergic terminal excitability following arrival of the nerve impulse: the influence of amphetamine and haloperidol. Brain research. vol 245. issue 1. 1982-12-02. PMID:6288195. |
neither amphetamine nor haloperidol had a significant effect on the excitability of dopaminergic axons in the medial forebrain bundle. |
1982-12-02 |
2023-08-12 |
rat |
| H Takeuchi, S J Young, P M Grove. Dopaminergic terminal excitability following arrival of the nerve impulse: the influence of amphetamine and haloperidol. Brain research. vol 245. issue 1. 1982-12-02. PMID:6288195. |
variations in dopaminergic terminal excitability after impulse arrival, and the effects of amphetamine and haloperidol on this phenomenon suggest that terminal excitability is determined by events related to arrival of the nerve impulse including activation of presynaptic 'autoreceptors' by dopamine released from the synaptic ending. |
1982-12-02 |
2023-08-12 |
rat |
| F Malouin, P J Bédar. Head turning induced by unilateral intracaudate thyrotropin-releasing hormone (TRH) injection in the cat. European journal of pharmacology. vol 81. issue 4. 1982-12-02. PMID:6811294. |
haloperidol, but not cyproheptadine pretreatment, decreased the level of head motility providing evidence that postural symmetry is modulated within the striatum, whereas head motility is regulated by extrastriatal dopaminergic mechanisms. |
1982-12-02 |
2023-08-12 |
cat |
| J McCulloch, H E Savaki, L Sokolof. Distribution of effects of haloperidol on energy metabolism in the rat brain. Brain research. vol 243. issue 1. 1982-12-02. PMID:7116160. |
the effects of the putative dopaminergic antagonist, haloperidol (0.01-10 mg/kg, i.v. |
1982-12-02 |
2023-08-12 |
rat |
| J McCulloch, H E Savaki, L Sokolof. Distribution of effects of haloperidol on energy metabolism in the rat brain. Brain research. vol 243. issue 1. 1982-12-02. PMID:7116160. |
the distribution of alterations in glucose utilization following haloperidol administration are considered in relation to the overall functional consequences of dopaminergic receptor blockade. |
1982-12-02 |
2023-08-12 |
rat |
| A Reches, H R Wagner, D Jiang, V Jackson, S Fah. The effect of chronic L-dopa administration on supersensitive pre- and postsynaptic dopaminergic receptors in rat brain. Life sciences. vol 31. issue 1. 1982-10-29. PMID:7109853. |
chronic administration of haloperidol induced supersensitivity of the pre- and postsynaptic dopaminergic receptors in rat brain. |
1982-10-29 |
2023-08-12 |
rat |