| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R M Threatte, M J Fregly, T M Connor, D C Kikt. L-5-Hydroxytryptophan-induced drinking in rats: possible mechanisms for induction. Pharmacology, biochemistry, and behavior. vol 14. issue 3. 1981-07-23. PMID:7015366. |
haloperidol (150 microgram/kg body weight, ip), a dopaminergic antagonist, also attenuated the dipsogenic response to administration of 5-htp. |
1981-07-23 |
2023-08-12 |
rat |
| A R Schonfeld, S D Glic. Handling-induced seizures and rotational behavior in th Mongolian gerbil. Pharmacology, biochemistry, and behavior. vol 14. issue 4. 1981-07-20. PMID:7195039. |
two dopaminergic agonists, amphetamine (4 mg/kg) and apomorphine (16 mg/kg) enhanced rotation at anticonvulsant doses while the dopaminergic antagonist haloperidol reduced rotational behavior at a dose (1 mg/kg) which exacerbate seizure severity. |
1981-07-20 |
2023-08-12 |
Not clear |
| M T Li. The catecholamine precursor L-3,4-dihydroxyphenylalanine inhibits both heat production and heat loss mechanisms in the rabbit. Canadian journal of physiology and pharmacology. vol 58. issue 8. 1981-07-20. PMID:7225933. |
further, the temperature effects induced by l-dopa were antagonized by pretreatment with 6-hydroxydopamine (a relative depletor of catecholaminergic nerve fibers) but not with haloperidol (a relative blocker of dopaminergic receptors). |
1981-07-20 |
2023-08-12 |
rabbit |
| C M Kuhn, S M Schanber. Maturation of central nervous system control of growth hormone secretion in rats. The Journal of pharmacology and experimental therapeutics. vol 217. issue 1. 1981-05-26. PMID:6970810. |
the 5-hydroxytryptophan-induced rise was prevented by the serotonergic antagonist cyproheptadine but not by the dopaminergic antagonist haloperidol. |
1981-05-26 |
2023-08-12 |
rat |
| U Halbreich, E J Sachar, R S Nathan, G M Asnis, F S Halper. The effect of benztropine mesylate on the prolactin response to haloperidol. Psychopharmacology. vol 72. issue 1. 1981-04-24. PMID:6781007. |
the interaction between cholinergic and dopaminergic systems in regulating prolactin responses was investigated in normal men by administration of haloperidol (0.5 mg im), with and without benztropine (1.0 and 2.0 mg im). |
1981-04-24 |
2023-08-12 |
human |
| V W Henderson, G F Woote. Neuroleptic malignant syndrome: a pathogenetic role for dopamine receptor blockade? Neurology. vol 31. issue 2. 1981-04-13. PMID:6110195. |
in a patient with parkinson disease and a chronic psychiatric disorder treated with haloperidol, typical features of nms appeared upon cessation of dopaminergic antiparkinsonian drugs. |
1981-04-13 |
2023-08-12 |
Not clear |
| G B Fregnan, T Chiel. Classical neuroleptics and deconditioning activity after single or repeated treatment. Role of different cerebral neurotransmitters. Arzneimittel-Forschung. vol 30. issue 11. 1981-03-27. PMID:6109537. |
the acute administration of some neuroleptics in combination with other centrally active drugs, endowed with different mechanism of action, yielded the following results on car: amphetamine (a dopaminergic stimulant) readily antagonized the effect of lr 511 and haloperidol; chlorpheniramine and diphenhydramine (antihistaminics) minimized the effect of small doses of lr 511 and haloperidol while they did not alter that of larger doses; atropine (an anti-cholinergic), metergoline (an anti-5-hydroxytryptaminic (5-ht) and cyproheptadine (an anti-5-ht possessing antihistaminic and anticholinergic properties) protentiated the effect of lr 511 while in part reduced that of haloperidol. |
1981-03-27 |
2023-08-12 |
rat |
| M Budek, A I Barkai, D L Brown, R R Fiev. Suppression of amphetamine-induced EEG arousal in the hippocampus of haloperidol-treated rabbits. Neuropsychobiology. vol 7. issue 2. 1981-03-27. PMID:7453955. |
it is suggested that the enhancement of hippocampal theta by d-amphetamine is mediated in part by dopaminergic mechanisms which are susceptible to the action of haloperidol. |
1981-03-27 |
2023-08-12 |
Not clear |
| A Fierro, M Sellini, L Marchesi, F Massimiani, C Giovannin. [Influence of haloperidol on blood cortisol response to lysine-8-vasopressin in normal subjects]. Bollettino della Societa italiana di biologia sperimentale. vol 55. issue 24. 1981-03-24. PMID:553571. |
the results show that haloperidol eliminates the cortisolemic response during stimulation with lvp; that is most likely, in relation to the specific blocking effect of this drug on dopaminergic receptors in the hypothalamus and on the hypothalamo-diencephalic pathways. |
1981-03-24 |
2023-08-11 |
human |
| S Govoni, J S Hong, H Y Yang, E Cost. Increase of neurotensin content elicited by neuroleptics in nucleus accumbens. The Journal of pharmacology and experimental therapeutics. vol 215. issue 2. 1981-02-26. PMID:6108359. |
the increase of neurotensin-ir content caused by haloperidol chloropromazine, trifluoroperazine and pimozide in accumbens and striatum suggests a modulation of neurotensin metabolism, synthesis or utilization directly or indirectly through dopaminergic synapses. |
1981-02-26 |
2023-08-12 |
rat |
| N J Dun, A G Karczma. A comparative study of the pharmacological properties of the positive potential recorded from the superior cervical ganglia of several species. The Journal of pharmacology and experimental therapeutics. vol 215. issue 2. 1981-02-26. PMID:6108360. |
dopaminergic receptor antagonists, haloperidol, chlorpromazine and metoclopramide, caused no significant depression of the p and ln responses in the rabbit scg. |
1981-02-26 |
2023-08-12 |
rat |
| I A Shalaby, L P Spea. Chronic administration of haloperidol during development: later psychopharmacological responses to apomorphine and arecoline. Pharmacology, biochemistry, and behavior. vol 13. issue 5. 1981-02-19. PMID:7192405. |
however, while control offspring exhibited a low dose (0.05 mg/kg apomorphine) suppression of matrix crossings and rearing behavior, haloperidol treated offspring did not, which may indicate a functional hyposensitivity of dopaminergic autoreceptors in these treated animals. |
1981-02-19 |
2023-08-12 |
rat |
| C F Saller, L A Chiod. Glucose suppresses basal firing and haloperidol-induced increases in the firing rate of central dopaminergic neurons. Science (New York, N.Y.). vol 210. issue 4475. 1981-01-29. PMID:6254155. |
glucose also prevents or reverses the increase in discharge rates of dopaminergic cells normally elicited by the antipsychotic agent haloperidol. |
1981-01-29 |
2023-08-12 |
rat |
| K Andreas, H D Fischer, E Rudolph, G Brösge. The influence of haloperidol pretreatment on the morphine toxicity. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement. vol 4. 1981-01-29. PMID:6933966. |
the influence of dopaminergic modifiers on morphine-induced analgesia and lethality was studied comparing both the effect of a single pre-dose of haloperidol and and continuous pretreatment for three weeks with haloperidol. |
1981-01-29 |
2023-08-12 |
Not clear |
| J Schmidt, K H Westerman. Effects of preceding sensibilization by reserpine and haloperidol on toxicity of dopaminergic agonists. Archives of toxicology. Supplement. = Archiv fur Toxikologie. Supplement. vol 4. 1981-01-29. PMID:6933968. |
effects of preceding sensibilization by reserpine and haloperidol on toxicity of dopaminergic agonists. |
1981-01-29 |
2023-08-12 |
mouse |
| M F Attie, E M Brown, D G Gardner, A M Spiegel, G D Aurbac. Characterization of the dopamine-responsive adenylate cyclase of bovine parathyroid cells and its relationship to parathyroid hormone secretion. Endocrinology. vol 107. issue 6. 1981-01-29. PMID:7428692. |
the dopaminergic antagonists chlorpromazine, fluphenazine, and haloperidol inhibited the da-stimulated adenylate cyclase. |
1981-01-29 |
2023-08-12 |
cattle |
| F Lechin, F Gômez, B van der Dijs, E Lechi. Distal colon motility in schizophrenic patients. Journal of clinical pharmacology. vol 20. issue 7. 1981-01-26. PMID:6107308. |
although the dopaminergic blocking agents (dba) haloperidol and sulpiride strongly inhibit distal colon motility in most nonpsychotic subjects (83 per cent), this effect was registered in only 10 per cent of the 30 schizophrenic patients investigated in the present study. |
1981-01-26 |
2023-08-12 |
human |
| G Delitala, T Yeo, A Grossman, N R Hathway, G M Besse. A comparison of the effects of four ergot derivatives on prolactin secretion by dispersed rat pituitary cells. The Journal of endocrinology. vol 87. issue 1. 1981-01-16. PMID:7430919. |
ther dopamine-receptor blocking drugs, metoclopramide and haloperidol, antagonized the prolactin release-inhibiting activity of the compounds; bromocriptine and lisuride showed the highest resistance to this dopaminergic blockade. |
1981-01-16 |
2023-08-12 |
rat |
| D E Casey, J Gerlach, E Christensso. Dopamine, acetylcholine, and GABA effects in acute dystonia in primates. Psychopharmacology. vol 70. issue 1. 1980-12-18. PMID:6775341. |
to clarify the etiology of neuroleptic-induced acute dystonic reactions, monkeys (cercopithecus aethiops) were treated with haloperidol at doses sufficient to evoke dystonia, and the effects of agents that influenced dopaminergic, cholinergic, or gabaergic neurotransmitters were evaluated. |
1980-12-18 |
2023-08-12 |
monkey |
| P Demenge, C Feuerstein, P Mouchet, B Gueri. Stereospecific binding of 3H-haloperidol in rat dorsal spinal cord. European journal of pharmacology. vol 66. issue 1. 1980-11-25. PMID:7408959. |
[3h]haloperidol as dopaminergic ligand used on pooled microdiscs punched from the rat dorsal spinal cord allowed detection of a stereospecific binding. |
1980-11-25 |
2023-08-12 |
rat |