| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Pizzolato, T T Soncrant, S I Rapopor. Haloperidol and cerebral metabolism in the conscious rat: relation to pharmacokinetics. Journal of neurochemistry. vol 43. issue 3. 1984-09-13. PMID:6540296. |
these results show that haloperidol has an effect on cns metabolic activity that is more widespread than would be predicted from the topography of the dopaminergic system; this may be due to indirect propagation of the primary effects of haloperidol. |
1984-09-13 |
2023-08-12 |
rat |
| F W Foong, M Sato. Neurotransmitter-blocking agents influence antinociceptive effects of carbamazepine, baclofen, pentazocine and morphine on bradykinin-induced trigeminal pain. Neuropharmacology. vol 23. issue 6. 1984-09-07. PMID:6146940. |
the influence of naloxone (a narcotic antagonist), bicuculline (a gaba antagonist), phentolamine (an alpha-blocking agent), propranolol (a beta-adrenergic blocking agent), haloperidol (a dopaminergic blocking agent), methysergide (a serotonergic blocking agent) and atropine (a muscarinic blocking agent), on the antinociceptive effects induced by carbamazepine, baclofen, pentazocine and morphine, were investigated with a new antinociception test, using the trigeminal pain induced by application of bradykinin onto the tooth pulp of the rat. |
1984-09-07 |
2023-08-12 |
rat |
| G P Ryan, J C Hackman, C J Wohlberg, R A Davidof. Spontaneous dorsal root potentials arise from interneuronal activity in the isolated frog spinal cord. Brain research. vol 301. issue 2. 1984-08-17. PMID:6203611. |
moreover, because sdrps were increased by application of yohimbine, corynanthine and propanolol and reduced by haloperidol, such interneurons may be under descending control of adrenergic and dopaminergic fibers. |
1984-08-17 |
2023-08-12 |
Not clear |
| S Lahiri, N Smatresk, M Pokorski, P Barnard, A Mokashi, K H McGrego. Dopaminergic efferent inhibition of carotid body chemoreceptors in chronically hypoxic cats. The American journal of physiology. vol 247. issue 1 Pt 2. 1984-08-17. PMID:6742232. |
this study confirmed that the efferent inhibition significantly increased in the chronically hypoxic cats and demonstrated that haloperidol blocked the efferent inhibition, suggesting that the mechanism of the augmented inhibition is dopaminergic. |
1984-08-17 |
2023-08-12 |
Not clear |
| D G Morgan, Y N Sinha, C E Finc. Chronic domperidone fails to increase striatal spiperone binding sites despite hyperprolactinemia: comparison with chronic haloperidol. Neuroendocrinology. vol 38. issue 5. 1984-07-13. PMID:6728123. |
mice were administered the dopaminergic antagonists haloperidol or domperidone in their drinking water for 2 or 21 days. |
1984-07-13 |
2023-08-12 |
mouse |
| A Reches, V Jackson-Lewis, S Fah. Lithium does not interact with haloperidol in the dopaminergic pathways of the rat brain. Psychopharmacology. vol 82. issue 4. 1984-07-09. PMID:6427824. |
lithium does not interact with haloperidol in the dopaminergic pathways of the rat brain. |
1984-07-09 |
2023-08-12 |
rat |
| C Ferretti, F Benfenati, M Cimino, G Vantini, M Lipartiti, G Muccioli, R di Carlo, S Alger. Effects of systemic and intracerebroventricular domperidone treatment on striatal and hypothalamic dopaminergic neurons. Medical biology. vol 61. issue 6. 1984-07-09. PMID:6676604. |
in this study we compared the effects of systemic administration of haloperidol (hal), a typical dopaminergic antagonist and of domperidone (dom), a dopamine (da) receptor blocker which does not cross the blood brain barrier but has a potency similar to hal at da receptors, on hypothalamic and striatal da system turnover (evaluated by means of hva and dopac levels) and prolactin (prl) secretion in male rats. |
1984-07-09 |
2023-08-12 |
rat |
| K Reymann, W Pohle, P Müller-Welde, T Ot. Dopaminergic innervation of the hippocampus: evidence for midbrain raphe neurons as the site of origin. Biomedica biochimica acta. vol 42. issue 10. 1984-05-30. PMID:6202300. |
the haloperidol sensitivity of the early component of hippocampal responses is interpreted as support of the morphological data about an ascending dopaminergic input from the median raphe nucleus to the hippocampus. |
1984-05-30 |
2023-08-12 |
rat |
| M T Lin, C F Chen, K S Chuan. Both dopaminergic and adrenergic receptors in the brain are involved in the behavioural excitation induced by dibutyryl 3',5'-adenosine monophosphate and aminophylline in the rat. Neuropharmacology. vol 23. issue 2A. 1984-05-30. PMID:6325988. |
the behavioural excitation produced by either dibutyryl cyclic-amp or aminophylline was antagonized by pretreatment with intraventricular injection of either two alpha-adrenergic antagonists (phentolamine and yohimbine) or a dopaminergic antagonist (haloperidol), but not with either a beta-adrenergic antagonist (propranolol) or a narcotic antagonist (naloxone). |
1984-05-30 |
2023-08-12 |
rat |
| A Nieoullon, L Kerkerian, N Dusticie. Presynaptic dopaminergic control of high affinity glutamate uptake in the striatum. Neuroscience letters. vol 43. issue 2-3. 1984-05-11. PMID:6143287. |
the dopaminergic antagonist haloperidol was shown not to influence that basal glu uptake but this neuroleptic highly potentiates the excitatory effects of cortical stimulations. |
1984-05-11 |
2023-08-12 |
rat |
| W L Collier, C Cavallotti, M de Rossi, F Ament. Dopamine-sensitive adenylate cyclase in rabbit renal artery. Neuroscience letters. vol 43. issue 2-3. 1984-05-11. PMID:6324039. |
the stimulation of camp levels elicited by dopamine was remarkably reduced by the dopamine receptor antagonists fluphenazine and haloperidol, but it was unaffected by the ergot-like dopaminergic agonist bromocriptine. |
1984-05-11 |
2023-08-12 |
rabbit |
| D Becú de Villalobos, M I Vacas, D P Cardinali, C Libertu. A developmental study of adenohypophyseal dopaminergic receptors and of haloperidol-induced prolactin release in rats. Brain research. vol 314. issue 2. 1984-05-10. PMID:6423213. |
the ontogenesis of adenohypophyseal dopamine receptors, assessed by haloperidol-displaceable [3h]didydroergocryptine (dhe) binding of 1-, 12-, 20-, 28-day-old female rats was studied in correlation with the prolactin releasing effect of haloperidol (1 mg/kg), a dopaminergic antagonist. |
1984-05-10 |
2023-08-12 |
rat |
| D Becú de Villalobos, M I Vacas, D P Cardinali, C Libertu. A developmental study of adenohypophyseal dopaminergic receptors and of haloperidol-induced prolactin release in rats. Brain research. vol 314. issue 2. 1984-05-10. PMID:6423213. |
as sex differences in the dopaminergic modulation of prolactin release have been documented, the hyperprolactinemic effect of haloperidol in correlation with [3h]dhe binding in anterior pituitary of 28-day-old female and male rats was studied. |
1984-05-10 |
2023-08-12 |
rat |
| D Becú de Villalobos, M I Vacas, D P Cardinali, C Libertu. A developmental study of adenohypophyseal dopaminergic receptors and of haloperidol-induced prolactin release in rats. Brain research. vol 314. issue 2. 1984-05-10. PMID:6423213. |
from then onwards, a gradual but slight increment in both, bmax and kd for the dopaminergic agonist is observed until puberty; (b) at 28 days, no clear difference in bmax and kd is present in [3h]dhe binding between male and female rats; (c) by contrast, haloperidol shows a prolactin releasing effect that increases markedly with age in the female. |
1984-05-10 |
2023-08-12 |
rat |
| G C Chio. Ocular hypotensive actions of haloperidol, a dopaminergic antagonist. Archives of ophthalmology (Chicago, Ill. : 1960). vol 102. issue 1. 1984-04-24. PMID:6703959. |
ocular hypotensive actions of haloperidol, a dopaminergic antagonist. |
1984-04-24 |
2023-08-12 |
cat |
| G C Chio. Ocular hypotensive actions of haloperidol, a dopaminergic antagonist. Archives of ophthalmology (Chicago, Ill. : 1960). vol 102. issue 1. 1984-04-24. PMID:6703959. |
haloperidol, a dopaminergic antagonist, was found to be very effective in suppressing the intraocular pressure recovery curve of rabbits infused with 20% saline intravenously. |
1984-04-24 |
2023-08-12 |
cat |
| D L Keegan, J S Richardson, A R Kirb. A possible neurochemical basis for the neuropsychiatric aspects of baclofen therapy. The International journal of neuroscience. vol 20. issue 3-4. 1984-04-13. PMID:6321374. |
this case demonstrates the interactive effects of baclofen and haloperidol on central noradrenergic and dopaminergic systems and suggests a possible neurochemical basis for the difference between delusional and nondelusional depression that is consistent with the different therapeutic response to psychotropic drugs of patients with these illnesses. |
1984-04-13 |
2023-08-12 |
Not clear |
| C Le Douarin, D Fage, B Scatto. Effects of cyclo (Leu-Gly) on neurochemical indices of striatal dopaminergic supersensitivity induced by prolonged haloperidol treatment. Life sciences. vol 34. issue 4. 1984-03-19. PMID:6694528. |
effects of cyclo (leu-gly) on neurochemical indices of striatal dopaminergic supersensitivity induced by prolonged haloperidol treatment. |
1984-03-19 |
2023-08-12 |
rat |
| B Klusha, V Georgiev, V Petkov, V Markovsk. Effects of the tripeptides TRH, MIF and MAF on the cerebral dopaminergic system. Acta physiologica et pharmacologica Bulgarica. vol 9. issue 2. 1984-02-24. PMID:6140814. |
the results obtained characterize trh and mif as drugs which are capable of activating the cerebral dopaminergic receptors by antagonizing the effects of reserpine and haloperidol, maf--as a substance acting similar to the dopaminergic receptor blockers. |
1984-02-24 |
2023-08-12 |
mouse |
| C Jue. Pre- and postsynaptic effects of dopamine antagonists on dopaminergic synaptic transmission in Helix pomatia. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 76. issue 1. 1984-01-27. PMID:6139250. |
the rate of transmitter mobilization in identified dopaminergic synapses was decreased by the dopamine antagonists pimozide, chlorpromazine, haloperidol, cis-flupenthixol, curare, clozapine and high concentrations of ergometrine. |
1984-01-27 |
2023-08-12 |
Not clear |