Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
D L Keegan, J S Richardson, A R Kirb. A possible neurochemical basis for the neuropsychiatric aspects of baclofen therapy. The International journal of neuroscience. vol 20. issue 3-4. 1984-04-13. PMID:6321374. |
this case demonstrates the interactive effects of baclofen and haloperidol on central noradrenergic and dopaminergic systems and suggests a possible neurochemical basis for the difference between delusional and nondelusional depression that is consistent with the different therapeutic response to psychotropic drugs of patients with these illnesses. |
1984-04-13 |
2023-08-12 |
Not clear |
C Le Douarin, D Fage, B Scatto. Effects of cyclo (Leu-Gly) on neurochemical indices of striatal dopaminergic supersensitivity induced by prolonged haloperidol treatment. Life sciences. vol 34. issue 4. 1984-03-19. PMID:6694528. |
effects of cyclo (leu-gly) on neurochemical indices of striatal dopaminergic supersensitivity induced by prolonged haloperidol treatment. |
1984-03-19 |
2023-08-12 |
rat |
B Klusha, V Georgiev, V Petkov, V Markovsk. Effects of the tripeptides TRH, MIF and MAF on the cerebral dopaminergic system. Acta physiologica et pharmacologica Bulgarica. vol 9. issue 2. 1984-02-24. PMID:6140814. |
the results obtained characterize trh and mif as drugs which are capable of activating the cerebral dopaminergic receptors by antagonizing the effects of reserpine and haloperidol, maf--as a substance acting similar to the dopaminergic receptor blockers. |
1984-02-24 |
2023-08-12 |
mouse |
C Jue. Pre- and postsynaptic effects of dopamine antagonists on dopaminergic synaptic transmission in Helix pomatia. Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology. vol 76. issue 1. 1984-01-27. PMID:6139250. |
the rate of transmitter mobilization in identified dopaminergic synapses was decreased by the dopamine antagonists pimozide, chlorpromazine, haloperidol, cis-flupenthixol, curare, clozapine and high concentrations of ergometrine. |
1984-01-27 |
2023-08-12 |
Not clear |
E Arribas, S Vega, C Benito, M P Fernandez-Tome, J del Ri. Synthesis and pharmacological study of the thiophene analogue of taclamine, QM-7184, a new neuroleptic drug with potent alpha-adrenoceptor blocking activity. Arzneimittel-Forschung. vol 33. issue 10. 1984-01-27. PMID:6140017. |
like other neuroleptics, qm-7184 blocks striatal dopaminergic receptors and consequently increases the concentration of homovanillic acid and displaces [3h]spiperone binding, although it is a less potent displacer than haloperidol or butaclamol. |
1984-01-27 |
2023-08-12 |
Not clear |
D K Sarkar, P E Gottschall, J Meites, A Horn, R C Dow, G Fink, A C Cuell. Uptake and release of [3H]dopamine by the median eminence: evidence for presynaptic dopaminergic receptors and for dopaminergic feedback inhibition. Neuroscience. vol 10. issue 3. 1984-01-27. PMID:6646431. |
the response to electrical stimulation was increased by nomifensine and by a dopaminergic antagonist, haloperidol, and was reduced by dopamine and by a dopaminergic agonist, piribedil. |
1984-01-27 |
2023-08-12 |
Not clear |
R D Huffman, M K Tick. The effects of chronic haloperidol administration on GABA receptor binding. Pharmacology, biochemistry, and behavior. vol 19. issue 2. 1983-12-20. PMID:6314387. |
the increase in gaba binding sites in the substantia nigra was evident for at least 4 days following termination of haloperidol treatment; however, 8 days following withdrawal from haloperidol, when dopaminergic supersensitivity had become maximally expressed, the number of gaba binding sites in the substantia nigra had declined and was the same as that observed in the control rats. |
1983-12-20 |
2023-08-12 |
rat |
D C Kikta, C C Barney, R M Threatte, M J Fregly, N E Rowland, J E Greenlea. On the mechanism of serotonin-induced dipsogenesis in the rat. Pharmacology, biochemistry, and behavior. vol 19. issue 3. 1983-12-20. PMID:6356172. |
serotonin (2 mg/kg, sc)-induced drinking was inhibited by the dopaminergic antagonist, haloperidol (150 micrograms/kg, ip), which also inhibits angiotensin ii-induced drinking. |
1983-12-20 |
2023-08-12 |
rat |
J M Farah, K T Demarest, K E Moor. A comparison of domperidone and haloperidol effects on different dopaminergic neurons in the rat brain. Life sciences. vol 33. issue 16. 1983-12-17. PMID:6633157. |
a comparison of domperidone and haloperidol effects on different dopaminergic neurons in the rat brain. |
1983-12-17 |
2023-08-12 |
rat |
J M Farah, K T Demarest, K E Moor. A comparison of domperidone and haloperidol effects on different dopaminergic neurons in the rat brain. Life sciences. vol 33. issue 16. 1983-12-17. PMID:6633157. |
domperidone, a dopamine (da) receptor antagonist with reportedly preferential actions outside of the blood-brain barrier, and haloperidol, a centrally active da antagonist, were compared with respect to their abilities to increase the activity of dopaminergic neurons in the rat brain. |
1983-12-17 |
2023-08-12 |
rat |
K Andreas, H D Fischer, J Schmid. [Effect of central effective substances on alcohol preference]. Biomedica biochimica acta. vol 42. issue 4. 1983-11-23. PMID:6138034. |
a single injection of haloperidol increases the preference, apomorphine as well as a long term haloperidol administration producing a dopaminergic supersensitivity diminishes the preference. |
1983-11-23 |
2023-08-12 |
mouse |
A M Nielsen, G E Bisgar. Dopaminergic modulation of respiratory timing mechanisms in carotid body-denervated dogs. Respiration physiology. vol 53. issue 1. 1983-11-23. PMID:6622865. |
the dopaminergic antagonist haloperidol produced a frequency-dependent decrease in basal phrenic minute activity and reversed or abolished apo-induced changes in the phrenic profile. |
1983-11-23 |
2023-08-12 |
Not clear |
S K Rastogi, R B Rastogi, R L Singhal, Y D Lapierr. Behavioural and biochemical alterations following haloperidol treatment and withdrawal: the animal model of tardive dyskinesia reexamined. Progress in neuro-psychopharmacology & biological psychiatry. vol 7. issue 2-3. 1983-10-28. PMID:6137027. |
these data suggest that chronic haloperidol treatment and subsequent withdrawal results in the development of behavioural dopamine supersensitivity as well as biochemical alterations in dopaminergic and gabaergic system. |
1983-10-28 |
2023-08-12 |
rat |
K Negishi, T Teranishi, S Kat. A GABA antagonist, bicuculline, exerts its uncoupling action on external horizontal cells through dopamine cells in carp retina. Neuroscience letters. vol 37. issue 3. 1983-10-28. PMID:6310453. |
these uncoupling actions of bcc were similar to those of amphetamine (20 microm) or dopamine (10-20 microm) and were abolished by the presence of a dopaminergic blocker, haloperidol (20-40 microm). |
1983-10-28 |
2023-08-12 |
Not clear |
G Meco, M Casacchia, M Attenni, A Iafrate, F Castellana, U Ecar. Haloperidol decanoate in schizophreniform disorders. Clinical and neuroendocrine aspects. Acta psychiatrica Belgica. vol 83. issue 1. 1983-10-08. PMID:6613612. |
these data indicate a dissociation between the effect of haloperidol after hd injection on the limbic dopaminergic system and the effect at the level of the tubero-infundibular system. |
1983-10-08 |
2023-08-12 |
Not clear |
J Sawyno. Monoamines as mediators of the antinociceptive effect of baclofen. Naunyn-Schmiedeberg's archives of pharmacology. vol 323. issue 1. 1983-09-23. PMID:6877393. |
blockade of noradrenergic and dopaminergic receptors with phentolamine, chlorpromazine and haloperidol produced similar increases. |
1983-09-23 |
2023-08-12 |
rat |
M Arluison, M P Martres, P Sokolof. High-resolution radioautographic study of dopamine binding sites in the rat neostriatum using 3H-domperidone. Journal of neural transmission. Supplementum. vol 18. 1983-09-20. PMID:6576121. |
when the animals were pretreated with haloperidol in order to block the dopaminergic binding sites, we found a decrease in the total number of the number of silver grains. |
1983-09-20 |
2023-08-12 |
rat |
J Z Nowak, S Arbilla, A M Galzin, S Z Lange. Changes in sensitivity of release modulating dopamine autoreceptors after chronic treatment with haloperidol. The Journal of pharmacology and experimental therapeutics. vol 226. issue 2. 1983-09-20. PMID:6875865. |
in summary, our results indicate that chronic haloperidol administration induces changes in sensitivity of the da autoreceptors regulating dopaminergic neurotransmission but does not affect the sensitivity of da receptors modulating ne release in the central nervous system. |
1983-09-20 |
2023-08-12 |
rabbit |
R Scorza-Smeraldi, M G Sabbadini Villa, G Fabio, P Bonara, M Vanoli, L Resele, C Zanuss. HLA antigens and the reactivity of lymphocytes to some drugs and PHA. International journal of immunopharmacology. vol 5. issue 2. 1983-09-09. PMID:6603432. |
peripheral blood lymphocytes from 15 healthy subjects, selected on the basis of their hla types, were cultured in vitro in the presence of pha and of a number of drugs which bind adrenergic or dopaminergic receptors (dopamine, norepinephrine, chlorpromazine, haloperidol, propranolol and apomorphine). |
1983-09-09 |
2023-08-12 |
human |
P R Sanber. Dopaminergic and cholinergic influences on motor behavior in chickens. Journal of comparative psychology (Washington, D.C. : 1983). vol 97. issue 1. 1983-09-09. PMID:6872506. |
studies of the interaction of dopaminergic and cholinergic systems showed that haloperidol could attenuate the activity-stimulating effects of scopolamine whereas pilocarpine had a similar, but lesser, effect on apomorphine-induced activity. |
1983-09-09 |
2023-08-12 |
Not clear |