| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A R Artalejo, A G García, C Montiel, P Sánchez-Garcí. A dopaminergic receptor modulates catecholamine release from the cat adrenal gland. The Journal of physiology. vol 362. 1985-09-12. PMID:4020691. |
haloperidol itself increased the nicotinic secretory response during s2; so, while the ratio s2/s1 was 0.5 in control conditions, this ratio increased significantly to 0.95 if haloperidol (0.5 microm) was present during s2, suggesting that the presence of this dopaminergic antagonist removed a negative feed-back mechanism that inhibits nicotine-evoked catecholamine release. |
1985-09-12 |
2023-08-11 |
cat |
| D G Kirch, M R Palmer, M Egan, R Freedma. Electrophysiological interactions between haloperidol and reduced haloperidol, and dopamine, norepinephrine and phencyclidine in rat brain. Neuropharmacology. vol 24. issue 5. 1985-08-26. PMID:2862598. |
haloperidol antagonized dopaminergic inhibition of caudate neurons and inhibition of cerebellar purkinje neurons induced by noradrenaline, whereas reduced haloperidol was an ineffective antagonist. |
1985-08-26 |
2023-08-11 |
rat |
| R D Blitzer, R E Becke. Characterization of the bupropion cue in the rat: lack of evidence for a dopaminergic mechanism. Psychopharmacology. vol 85. issue 2. 1985-08-12. PMID:2861618. |
despite bupropion's established dopaminergic activity in vitro and in vivo, it was found that the bupropion cue was neither mimicked by the dopaminergic drugs l-dopa and bromocriptine nor blocked by a variety of neuroleptics (haloperidol, thioridazine, and thiothixene). |
1985-08-12 |
2023-08-11 |
rat |
| D Jezová, J Jurcovicová, M Vigas, K Murgas, F Labri. Increase in plasma ACTH after dopaminergic stimulation in rats. Psychopharmacology. vol 85. issue 2. 1985-08-12. PMID:2989967. |
the effects of a dopaminergic agonist, apomorphine, and a dopaminergic antagonist, haloperidol, on plasma acth, and corticosterone levels were evaluated in adult male rats. |
1985-08-12 |
2023-08-11 |
rat |
| W R Klem. Evidence for a cholinergic role in haloperidol-induced catalepsy. Psychopharmacology. vol 85. issue 2. 1985-08-12. PMID:3925479. |
low doses of pilocarpine caused a pronounced enhancement of the catalepsy that was induced by the dopaminergic blocker, haloperidol. |
1985-08-12 |
2023-08-11 |
mouse |
| C S Tsai, R F Ochill. Comparative studies of cardiovascular effects of a new dopamine agonist (SK&F 38393A) and dopamine. General pharmacology. vol 16. issue 2. 1985-07-22. PMID:3873379. |
haloperidol (10(-6) m), a dopaminergic receptor blocker, did not block the cardiovascular effects of daa and da. |
1985-07-22 |
2023-08-11 |
Not clear |
| M O Maĭmets, E E Vasar, A M Nurk, L Kh Allikmet. [Role of serotonin and dopamine receptors in the mechanism of action of haloperidol and pirenperone]. Farmakologiia i toksikologiia. vol 48. issue 2. 1985-07-18. PMID:3996566. |
acute administration of haloperidol had effects mainly in dopaminergic models, whereas pirenperone was active only in serotoninergic models. |
1985-07-18 |
2023-08-11 |
Not clear |
| J S Hong, K Yoshikawa, T Kanamatsu, S L Sabo. Modulation of striatal enkephalinergic neurons by antipsychotic drugs. Federation proceedings. vol 44. issue 9. 1985-07-17. PMID:3838946. |
several lines of evidence, which showed that striatal levels of [met5]enkephalin (me) increase after the nigrostriatal dopaminergic pathway was interrupted by hemitransection or direct administration of 6-hydroxydopamine to the substantia nigra, or after repeated injections of either reserpine or haloperidol, suggest that dopamine (da) plays an important role in regulating the metabolism of me-containing neurons in the striatum. |
1985-07-17 |
2023-08-11 |
rat |
| M Ikeda, H Miyazaki, A Matsushit. Simultaneous monitoring of electrochemical and unitary neuronal activities by a single carbon fiber microelectrode. Japanese journal of pharmacology. vol 37. issue 3. 1985-07-17. PMID:3999480. |
the effects of haloperidol on the level of catecholamines in extracellular spaces and on dopaminergic neuronal discharges were investigated. |
1985-07-17 |
2023-08-11 |
rat |
| P K Randall, J A Severson, S M Hurd, W O McClur. Effect of duration of haloperidol treatment on DA receptor supersensitization in aging C57BL/6J mice. Brain research. vol 333. issue 1. 1985-07-02. PMID:4039618. |
apomorphine-induced behavior, striatal [3h]spiperone binding, and striatal choline acetyltransferase (chat) activity were assessed in 6 1/2, 13, and 27-30 month-old male c57bl/6j mice following 0, 30, 60 or 90 days treatment with the dopaminergic (da) antagonist haloperidol. |
1985-07-02 |
2023-08-11 |
mouse |
| D Zhelyazkov, M Markov, A Maleeva, N Visheva, V Milko. Neuro-endocrine effects of isotheoline. Acta physiologica et pharmacologica Bulgarica. vol 10. issue 4. 1985-06-27. PMID:6535370. |
comparative experiments were carried out with bromocryptine and glaucine--1 mg/kg i.p., as well as experiments involving the administration of ist on the background of the dopaminergic antagonists haloperidol and pymoside--1 mg/kg i.p. |
1985-06-27 |
2023-08-12 |
rat |
| G Boschi, N Launa. Differential effects of neuroleptic and serotonergic drugs on amphetamine-induced hypothermia in mice. Neuropharmacology. vol 24. issue 2. 1985-06-19. PMID:2859540. |
pretreatment with the dopaminergic (da) receptor antagonist haloperidol reduced this response, whereas pretreatment with pimozide, sulpiride or cis-flupentixol did not. |
1985-06-19 |
2023-08-11 |
mouse |
| E Meller, K Bohmaker, M Goldstein, J W Schweitzer, A J Friedhof. Chronic haloperidol does not alter agonist affinity for dopamine receptors in vitro. European journal of pharmacology. vol 109. issue 3. 1985-06-19. PMID:3157587. |
although this agent only displays potent dopaminergic agonism in supersensitive animals, chronic treatment with haloperidol likewise did not alter the affinity of this drug for [3h]spiperone binding sites. |
1985-06-19 |
2023-08-11 |
rat |
| O Gaffori, J M Van Re. Serotonin and antidepressant drugs antagonize melatonin-induced behavioural changes after injection into the nucleus accumbens of rats. Neuropharmacology. vol 24. issue 3. 1985-06-18. PMID:2859542. |
the action of melatonin is apparently not mediated by dopaminergic systems, because the behavioural changes were not antagonized by local pretreatment with haloperidol or sulpiride. |
1985-06-18 |
2023-08-11 |
rat |
| G D Vogelsang, M F Pierce. The supersensitivity of dopaminergic neurons to apomorphine in rats following chronic haloperidol. European journal of pharmacology. vol 110. issue 2. 1985-06-18. PMID:3987817. |
the supersensitivity of dopaminergic neurons to apomorphine in rats following chronic haloperidol. |
1985-06-18 |
2023-08-11 |
rat |
| M Toru, M Takashim. Haloperidol in large doses reduces the cataleptic response and increases noradrenaline metabolism in the brain of the rat. Neuropharmacology. vol 24. issue 3. 1985-06-18. PMID:4039420. |
the result may indicate that the increased metabolism of noradrenaline by large doses of haloperidol was not secondary to the blocking of dopaminergic receptors. |
1985-06-18 |
2023-08-11 |
rat |
| T Nishikawa, B Scatto. Inhibitory influence of GABA on central serotonergic transmission. Involvement of the habenulo-raphé pathways in the GABAergic inhibition of ascending cerebral serotonergic neurons. Brain research. vol 331. issue 1. 1985-06-14. PMID:2985200. |
), or alteration of central dopaminergic transmission (by systemic administration of apomorphine or haloperidol) failed to modify the ability of progabide (400 mg/kg i.p.) |
1985-06-14 |
2023-08-11 |
rat |
| F G Gonon, M J Bud. Regulation of dopamine release by impulse flow and by autoreceptors as studied by in vivo voltammetry in the rat striatum. Neuroscience. vol 14. issue 3. 1985-06-14. PMID:2986044. |
administration of dopaminergic antagonists such as haloperidol (0.05 and 0.5 mg/kg) or metoclopramide (2 mg/kg) significantly increased the dopamine current up to 317, 340 and 215% of the respective control values. |
1985-06-14 |
2023-08-11 |
rat |
| F G Gonon, M J Bud. Regulation of dopamine release by impulse flow and by autoreceptors as studied by in vivo voltammetry in the rat striatum. Neuroscience. vol 14. issue 3. 1985-06-14. PMID:2986044. |
the effect of electrical stimulation of the dopaminergic pathway was potentiated by drugs such as amphetamine (2 mg/kg), nomifensine (4 mg/kg) or haloperidol (0.05 and 0.5 mg/kg) but was not altered by apomorphine (0.05 mg/kg). |
1985-06-14 |
2023-08-11 |
rat |
| J M Palacios, K H Wiederhol. Dopamine D2 receptor agents, but not dopamine D1, modify brain glucose metabolism. Brain research. vol 327. issue 1-2. 1985-06-10. PMID:3157422. |
the administration of ly-141865 or ym-09151-2, which behave as a specific d2 agonist and antagonist respectively, modified brain glucose metabolism in a manner similar to that previously described for more classical dopaminergic agents, such as apomorphine and haloperidol. |
1985-06-10 |
2023-08-11 |
Not clear |