| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L Williams-Hemby, L J Porrin. II. Functional consequences of intragastrically administered ethanol in rats as measured by the 2-[14C]deoxyglucose method: the contribution of dopamine. Alcoholism, clinical and experimental research. vol 21. issue 9. 1998-02-13. PMID:9438516. |
as outlined in the companion paper, many of the changes in functional activity produced by acute intragastric ethanol administration as determined by the quantitative autoradiographic 2-[14c]deoxyglucose method occur in structures of the mesocorticolimbic and nigrostriatal dopamine circuits. |
1998-02-13 |
2023-08-12 |
rat |
| L Williams-Hemby, L J Porrin. II. Functional consequences of intragastrically administered ethanol in rats as measured by the 2-[14C]deoxyglucose method: the contribution of dopamine. Alcoholism, clinical and experimental research. vol 21. issue 9. 1998-02-13. PMID:9438516. |
these findings suggest that the contribution of dopamine to the increases in functional activity are more complex at higher doses of ethanol. |
1998-02-13 |
2023-08-12 |
rat |
| P Olausson, M Ericson, A Petersson, A Kosowski, B Söderpalm, J A Enge. Nefazodone attenuates the behavioral and neurochemical effects of ethanol. Alcohol (Fayetteville, N.Y.). vol 15. issue 1. 1998-02-02. PMID:9426841. |
increased extracellular accumbal dopamine levels by 36% (p = 0.0073) compared to baseline levels, and elevated the maximal dopac and hva levels by 26% (p = 0.0093) and 52% (p = 0.0010), respectively, nefazodone (50 mg/kg, s.c.) per se increased accumbal dopamine levels by 28% (p = 0.0199) but, when injected 40 min before ethanol, reduced the ethanol-induced elevation of accumbal dopamine overflow (p = 0.0132) and decreased the ethanol-induced hva levels (p = 0.0159). |
1998-02-02 |
2023-08-12 |
rat |
| P Olausson, M Ericson, A Petersson, A Kosowski, B Söderpalm, J A Enge. Nefazodone attenuates the behavioral and neurochemical effects of ethanol. Alcohol (Fayetteville, N.Y.). vol 15. issue 1. 1998-02-02. PMID:9426841. |
these results show that nefazodone modulates the mesolimbic dopamine system in a dopamine activity-dependent manner, and influences the neurochemical and behavioral effects of ethanol in the rat. |
1998-02-02 |
2023-08-12 |
rat |
| Y M Wang, R R Gainetdinov, F Fumagalli, F Xu, S R Jones, C B Bock, G W Miller, R M Wightman, M G Caro. Knockout of the vesicular monoamine transporter 2 gene results in neonatal death and supersensitivity to cocaine and amphetamine. Neuron. vol 19. issue 6. 1998-01-29. PMID:9427251. |
the observed changes in presynaptic homeostasis are accompanied by a pronounced supersensitivity of the mice to the locomotor effects of the dopamine agonist apomorphine, the psychostimulants cocaine and amphetamine, and ethanol. |
1998-01-29 |
2023-08-12 |
mouse |
| O Blomqvist, M Ericson, J A Engel, B Söderpal. Accumbal dopamine overflow after ethanol: localization of the antagonizing effect of mecamylamine. European journal of pharmacology. vol 334. issue 2-3. 1998-01-22. PMID:9369343. |
accumbal dopamine overflow after ethanol: localization of the antagonizing effect of mecamylamine. |
1998-01-22 |
2023-08-12 |
Not clear |
| O Blomqvist, M Ericson, J A Engel, B Söderpal. Accumbal dopamine overflow after ethanol: localization of the antagonizing effect of mecamylamine. European journal of pharmacology. vol 334. issue 2-3. 1998-01-22. PMID:9369343. |
it has been suggested that ethanol exerts its mesolimbic dopamine activating effects and its reinforcing effects via interaction with central nicotinic acetylcholine receptors, thus providing a basis for the often observed covariation between ethanol and nicotine consumption. |
1998-01-22 |
2023-08-12 |
Not clear |
| O Blomqvist, M Ericson, J A Engel, B Söderpal. Accumbal dopamine overflow after ethanol: localization of the antagonizing effect of mecamylamine. European journal of pharmacology. vol 334. issue 2-3. 1998-01-22. PMID:9369343. |
furthermore, the increase in accumbal dopamine overflow after systemic ethanol (2.5 g/kg, i.p.) |
1998-01-22 |
2023-08-12 |
Not clear |
| Y Wang, M R Palmer, E J Cline, G A Gerhard. Effects of ethanol on striatal dopamine overflow and clearance: an in vivo electrochemical study. Alcohol (Fayetteville, N.Y.). vol 14. issue 6. 1998-01-08. PMID:9401676. |
effects of ethanol on striatal dopamine overflow and clearance: an in vivo electrochemical study. |
1998-01-08 |
2023-08-12 |
rat |
| Y Wang, M R Palmer, E J Cline, G A Gerhard. Effects of ethanol on striatal dopamine overflow and clearance: an in vivo electrochemical study. Alcohol (Fayetteville, N.Y.). vol 14. issue 6. 1998-01-08. PMID:9401676. |
previous studies have shown that the neurotransmitter dopamine (da) is implicated in the reinforcing effects of ethanol and other abused drugs. |
1998-01-08 |
2023-08-12 |
rat |
| C Cohen, G Perrault, D J Sange. Evidence for the involvement of dopamine receptors in ethanol-induced hyperactivity in mice. Neuropharmacology. vol 36. issue 8. 1998-01-07. PMID:9294975. |
the mesolimbic dopamine (da) system, ethanol-induced hyperactivity might provide a screening model to investigate the effect of ethanol on reward pathways. |
1998-01-07 |
2023-08-12 |
mouse |
| P Nestby, L J Vanderschuren, T J De Vries, F Hogenboom, G Wardeh, A H Mulder, A N Schoffelmee. Ethanol, like psychostimulants and morphine, causes long-lasting hyperreactivity of dopamine and acetylcholine neurons of rat nucleus accumbens: possible role in behavioural sensitization. Psychopharmacology. vol 133. issue 1. 1997-11-14. PMID:9335083. |
ethanol, like psychostimulants and morphine, causes long-lasting hyperreactivity of dopamine and acetylcholine neurons of rat nucleus accumbens: possible role in behavioural sensitization. |
1997-11-14 |
2023-08-12 |
rat |
| H H Kerschbaum, A Herman. Ethanol suppresses neuronal Ca2+ currents by effects on intracellular signal transduction. Brain research. vol 765. issue 1. 1997-11-06. PMID:9310391. |
in the presence of dopamine, which is known to suppress ca2+ currents by g0-protein activation, ethanol application was ineffective. |
1997-11-06 |
2023-08-12 |
Not clear |
| S Ikemoto, W J McBride, J M Murphy, L Lumeng, T K L. 6-OHDA-lesions of the nucleus accumbens disrupt the acquisition but not the maintenance of ethanol consumption in the alcohol-preferring P line of rats. Alcoholism, clinical and experimental research. vol 21. issue 6. 1997-11-04. PMID:9309315. |
the aim of the present study was to determine whether reduction of dopamine (da) innervation to the nucleus accumbens (acb) alters the maintenance and/or acquisition of ethanol drinking in female alcohol-preferring p rats. |
1997-11-04 |
2023-08-12 |
rat |
| H H Samson, C W Hodge, H L Erickson, J S Niehus, G A Gerhardt, P W Kalivas, E A Floy. The effects of local application of ethanol in the n. accumbens on dopamine overflow and clearance. Alcohol (Fayetteville, N.Y.). vol 14. issue 5. 1997-10-31. PMID:9305464. |
the effects of local application of ethanol in the n. accumbens on dopamine overflow and clearance. |
1997-10-31 |
2023-08-12 |
rat |
| H H Samson, C W Hodge, H L Erickson, J S Niehus, G A Gerhardt, P W Kalivas, E A Floy. The effects of local application of ethanol in the n. accumbens on dopamine overflow and clearance. Alcohol (Fayetteville, N.Y.). vol 14. issue 5. 1997-10-31. PMID:9305464. |
the actions of ethanol on extracellular dopamine levels in the n. accumbens were examined in both anesthetized and unanesthetized rats using either in vivo voltammetry or microdialysis. |
1997-10-31 |
2023-08-12 |
rat |
| H H Samson, C W Hodge, H L Erickson, J S Niehus, G A Gerhardt, P W Kalivas, E A Floy. The effects of local application of ethanol in the n. accumbens on dopamine overflow and clearance. Alcohol (Fayetteville, N.Y.). vol 14. issue 5. 1997-10-31. PMID:9305464. |
the voltammetry studies failed to find any direct effect of local ethanol on extracellular dopamine levels. |
1997-10-31 |
2023-08-12 |
rat |
| H H Samson, C W Hodge, H L Erickson, J S Niehus, G A Gerhardt, P W Kalivas, E A Floy. The effects of local application of ethanol in the n. accumbens on dopamine overflow and clearance. Alcohol (Fayetteville, N.Y.). vol 14. issue 5. 1997-10-31. PMID:9305464. |
however, exposure to high ethanol concentrations directly injected into the n. accumbens showed the rise rate and the return to baseline rate to a n. accumbens kcl-stimulated dopamine release. |
1997-10-31 |
2023-08-12 |
rat |
| H H Samson, C W Hodge, H L Erickson, J S Niehus, G A Gerhardt, P W Kalivas, E A Floy. The effects of local application of ethanol in the n. accumbens on dopamine overflow and clearance. Alcohol (Fayetteville, N.Y.). vol 14. issue 5. 1997-10-31. PMID:9305464. |
however, in the anesthetized rats, the extracellular dopamine levels were not increased, even with similar local ethanol levels measured in the dialysate. |
1997-10-31 |
2023-08-12 |
rat |
| H H Samson, C W Hodge, H L Erickson, J S Niehus, G A Gerhardt, P W Kalivas, E A Floy. The effects of local application of ethanol in the n. accumbens on dopamine overflow and clearance. Alcohol (Fayetteville, N.Y.). vol 14. issue 5. 1997-10-31. PMID:9305464. |
taken together, the data suggest that the actions of ethanol to increase extracellular dopamine levels in the n. accumbens are most likely not an effect of ethanol at the level of the accumbens but rather an action which increases neural activity within the mesoaccumbens pathway, perhaps via actions at the ventral tegmental area. |
1997-10-31 |
2023-08-12 |
rat |